EP1079967A4 - Flüssige markierung mit fluorezierenden mikropartikeln - Google Patents
Flüssige markierung mit fluorezierenden mikropartikelnInfo
- Publication number
- EP1079967A4 EP1079967A4 EP99917429A EP99917429A EP1079967A4 EP 1079967 A4 EP1079967 A4 EP 1079967A4 EP 99917429 A EP99917429 A EP 99917429A EP 99917429 A EP99917429 A EP 99917429A EP 1079967 A4 EP1079967 A4 EP 1079967A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- fluorescent microparticles
- liquid labeling
- labeling
- liquid
- microparticles
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
-
- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06K—GRAPHICAL DATA READING; PRESENTATION OF DATA; RECORD CARRIERS; HANDLING RECORD CARRIERS
- G06K19/00—Record carriers for use with machines and with at least a part designed to carry digital markings
- G06K19/06—Record carriers for use with machines and with at least a part designed to carry digital markings characterised by the kind of the digital marking, e.g. shape, nature, code
- G06K19/06009—Record carriers for use with machines and with at least a part designed to carry digital markings characterised by the kind of the digital marking, e.g. shape, nature, code with optically detectable marking
-
- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06K—GRAPHICAL DATA READING; PRESENTATION OF DATA; RECORD CARRIERS; HANDLING RECORD CARRIERS
- G06K19/00—Record carriers for use with machines and with at least a part designed to carry digital markings
- G06K19/06—Record carriers for use with machines and with at least a part designed to carry digital markings characterised by the kind of the digital marking, e.g. shape, nature, code
- G06K2019/06215—Aspects not covered by other subgroups
- G06K2019/06234—Aspects not covered by other subgroups miniature-code
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- General Physics & Mathematics (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Theoretical Computer Science (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8148798P | 1998-04-13 | 1998-04-13 | |
| US81487P | 1998-04-13 | ||
| PCT/US1999/007993 WO1999052708A1 (en) | 1998-04-13 | 1999-04-13 | Liquid labeling with fluorescent microparticles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP1079967A1 EP1079967A1 (de) | 2001-03-07 |
| EP1079967A4 true EP1079967A4 (de) | 2003-07-23 |
Family
ID=22164502
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP99917429A Withdrawn EP1079967A4 (de) | 1998-04-13 | 1999-04-13 | Flüssige markierung mit fluorezierenden mikropartikeln |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP1079967A4 (de) |
| AU (1) | AU3555599A (de) |
| WO (1) | WO1999052708A1 (de) |
Families Citing this family (114)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6696304B1 (en) | 1999-02-24 | 2004-02-24 | Luminex Corporation | Particulate solid phase immobilized protein quantitation |
| US6759235B2 (en) | 2000-04-06 | 2004-07-06 | Quantum Dot Corporation | Two-dimensional spectral imaging system |
| FR2812300B1 (fr) * | 2000-07-28 | 2003-01-10 | Cypher Science | Encre liquide securisee revelable optiquement et procede de marquage de produits par une telle encre |
| US7465540B2 (en) | 2000-09-21 | 2008-12-16 | Luminex Corporation | Multiple reporter read-out for bioassays |
| US20020142345A1 (en) * | 2000-12-22 | 2002-10-03 | Nelsen Anita J. | Methods for encoding and decoding complex mixtures in arrayed assays |
| US7473767B2 (en) | 2001-07-03 | 2009-01-06 | The Institute For Systems Biology | Methods for detection and quantification of analytes in complex mixtures |
| EP2196544A1 (de) | 2001-11-21 | 2010-06-16 | Applied Biosystems, LLC | Kit für Ligationsdetektionsreaktionen unter Verwendung von kodierten Markern |
| EP1900827A3 (de) | 2002-05-21 | 2008-04-16 | Bayer HealthCare AG | Verfahren und Zusammensetzungen zur Vorhersage, Diagnose, Prognose, Verhinderung und Behandlung maligner Neoplasien |
| GB0222728D0 (en) * | 2002-10-01 | 2002-11-06 | Shell Int Research | System for identifying lubricating oils |
| US7312257B2 (en) | 2003-01-23 | 2007-12-25 | General Electric Company | Polymer encapsulation of high aspect ratio materials and methods of making same |
| US7323696B2 (en) | 2004-01-09 | 2008-01-29 | Applera Corporation | Phosphor particle coded beads |
| US20050277710A1 (en) * | 2004-06-14 | 2005-12-15 | Joyce Richard P | Tagged resin, method of making a tagged resin, and articles made therefrom |
| CA2583531A1 (en) | 2004-10-12 | 2006-04-27 | Luminex Corporation | Methods for forming dyed microspheres and populations of dyed microspheres |
| US7470731B2 (en) | 2005-06-24 | 2008-12-30 | Pitney Bowes Inc. | Fluorescent ink |
| DE102005062027A1 (de) | 2005-12-22 | 2007-06-28 | Basf Ag | Wässrige Dispersionen von Polymeren, die einen Fluoreszenzfarbstoff enthalten, Verfahren zu ihrer Herstellung und ihre Verwendung zum Markieren von Materialien |
| WO2007076129A2 (en) | 2005-12-23 | 2007-07-05 | Nanostring Technologies, Inc. | Nanoreporters and methods of manufacturing and use thereof |
| WO2008109176A2 (en) | 2007-03-07 | 2008-09-12 | President And Fellows Of Harvard College | Assays and other reactions involving droplets |
| CN101946010B (zh) | 2007-12-21 | 2014-08-20 | 哈佛大学 | 用于核酸测序的系统和方法 |
| GB0725153D0 (en) * | 2007-12-21 | 2008-01-30 | Medinnova As | Protein analysis |
| US20110218123A1 (en) | 2008-09-19 | 2011-09-08 | President And Fellows Of Harvard College | Creation of libraries of droplets and related species |
| EP3290531B1 (de) | 2008-12-19 | 2019-07-24 | President and Fellows of Harvard College | Partikelunterstützte nukleinsäuresequenzierung |
| CA2778816C (en) | 2009-10-27 | 2018-07-31 | President And Fellows Of Harvard College | Droplet creation techniques |
| EP2513015B1 (de) | 2009-12-18 | 2019-03-13 | Construction Research & Technology GmbH | Verfahren zur qualitativen und quantitativen identifizierung von massengütern |
| EP4361608A3 (de) | 2012-02-03 | 2024-07-24 | California Institute of Technology | Signalkodierung und -dekodierung in multiplexierten biochemischen assays |
| EP3901243A1 (de) | 2012-08-03 | 2021-10-27 | California Institute of Technology | Multiplexing und quantifizierung in pcr mit reduzierter hardware und reduzierten anforderungen |
| US10221442B2 (en) | 2012-08-14 | 2019-03-05 | 10X Genomics, Inc. | Compositions and methods for sample processing |
| US10584381B2 (en) | 2012-08-14 | 2020-03-10 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| US11591637B2 (en) | 2012-08-14 | 2023-02-28 | 10X Genomics, Inc. | Compositions and methods for sample processing |
| US10323279B2 (en) | 2012-08-14 | 2019-06-18 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| US9701998B2 (en) | 2012-12-14 | 2017-07-11 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| US10752949B2 (en) | 2012-08-14 | 2020-08-25 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| US10273541B2 (en) | 2012-08-14 | 2019-04-30 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| US9951386B2 (en) | 2014-06-26 | 2018-04-24 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| EP4397767A3 (de) | 2012-08-14 | 2024-07-31 | 10X Genomics, Inc. | Mikrokapselzusammensetzungen und verfahren |
| WO2014093676A1 (en) | 2012-12-14 | 2014-06-19 | 10X Technologies, Inc. | Methods and systems for processing polynucleotides |
| US10533221B2 (en) | 2012-12-14 | 2020-01-14 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| CN108753766A (zh) | 2013-02-08 | 2018-11-06 | 10X基因组学有限公司 | 多核苷酸条形码生成 |
| US10395758B2 (en) | 2013-08-30 | 2019-08-27 | 10X Genomics, Inc. | Sequencing methods |
| US20160279068A1 (en) | 2013-11-08 | 2016-09-29 | President And Fellows Of Harvard College | Microparticles, methods for their preparation and use |
| FR3013846A1 (fr) | 2013-11-22 | 2015-05-29 | Jacques Degroote | Methode de marquage chimique de lots de dioxyde de carbone en vue d'en assurer la tracabilite |
| US9824068B2 (en) | 2013-12-16 | 2017-11-21 | 10X Genomics, Inc. | Methods and apparatus for sorting data |
| CA2943624A1 (en) | 2014-04-10 | 2015-10-15 | 10X Genomics, Inc. | Fluidic devices, systems, and methods for encapsulating and partitioning reagents, and applications of same |
| US12312640B2 (en) | 2014-06-26 | 2025-05-27 | 10X Genomics, Inc. | Analysis of nucleic acid sequences |
| AU2015279617A1 (en) | 2014-06-26 | 2017-01-12 | 10X Genomics, Inc. | Analysis of nucleic acid sequences |
| EP3161160B1 (de) | 2014-06-26 | 2021-10-13 | 10X Genomics, Inc. | Verfahren zur analyse von nukleinsäuren aus einzelzellen oder zellpopulationen |
| EP3161700B1 (de) | 2014-06-26 | 2023-03-29 | 10X Genomics, Inc. | Verfahren und systeme zur nukleinsäuresequenzanordnung |
| MX2017005267A (es) | 2014-10-29 | 2017-07-26 | 10X Genomics Inc | Metodos y composiciones para la secuenciacion de acidos nucleicos seleccionados como diana. |
| US9975122B2 (en) | 2014-11-05 | 2018-05-22 | 10X Genomics, Inc. | Instrument systems for integrated sample processing |
| CN107427808B (zh) | 2015-01-12 | 2020-10-23 | 10X基因组学有限公司 | 用于制备核酸测序文库的方法和系统以及用其制备的文库 |
| KR20170106979A (ko) | 2015-01-13 | 2017-09-22 | 10엑스 제노믹스, 인크. | 구조 변이 및 위상 조정 정보를 시각화하기 위한 시스템 및 방법 |
| EP3256606B1 (de) | 2015-02-09 | 2019-05-22 | 10X Genomics, Inc. | Systeme und verfahren zur bestimmung struktureller varianten |
| AU2016222719B2 (en) | 2015-02-24 | 2022-03-31 | 10X Genomics, Inc. | Methods for targeted nucleic acid sequence coverage |
| US10697000B2 (en) | 2015-02-24 | 2020-06-30 | 10X Genomics, Inc. | Partition processing methods and systems |
| US20160371704A1 (en) * | 2015-06-18 | 2016-12-22 | Kuantag Nanoteknolojiler Gelistirme Ve Uretim A.S. | Integrated fuel tracking system |
| CA3001679A1 (en) | 2015-10-13 | 2017-04-20 | President And Fellows Of Harvard College | Systems and methods for making and using gel microspheres |
| US11371094B2 (en) | 2015-11-19 | 2022-06-28 | 10X Genomics, Inc. | Systems and methods for nucleic acid processing using degenerate nucleotides |
| KR20240161696A (ko) | 2015-12-04 | 2024-11-12 | 10엑스 제노믹스, 인크. | 핵산 분석을 위한 방법 및 조성물 |
| CN108779491B (zh) | 2016-02-11 | 2021-03-09 | 10X基因组学有限公司 | 用于全基因组序列数据的从头组装的系统、方法和介质 |
| WO2017197343A2 (en) | 2016-05-12 | 2017-11-16 | 10X Genomics, Inc. | Microfluidic on-chip filters |
| WO2017197338A1 (en) | 2016-05-13 | 2017-11-16 | 10X Genomics, Inc. | Microfluidic systems and methods of use |
| WO2017218777A1 (en) | 2016-06-17 | 2017-12-21 | California Institute Of Technology | Nucleic acid reactions and related methods and compositions |
| US10815525B2 (en) | 2016-12-22 | 2020-10-27 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| US10550429B2 (en) | 2016-12-22 | 2020-02-04 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| US10011872B1 (en) | 2016-12-22 | 2018-07-03 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| EP4029939B1 (de) | 2017-01-30 | 2023-06-28 | 10X Genomics, Inc. | Verfahren und systeme für eine einzelzellbarcodierung auf tröpfchenbasis |
| US12264411B2 (en) | 2017-01-30 | 2025-04-01 | 10X Genomics, Inc. | Methods and systems for analysis |
| US10995333B2 (en) | 2017-02-06 | 2021-05-04 | 10X Genomics, Inc. | Systems and methods for nucleic acid preparation |
| WO2018213774A1 (en) | 2017-05-19 | 2018-11-22 | 10X Genomics, Inc. | Systems and methods for analyzing datasets |
| US10844372B2 (en) | 2017-05-26 | 2020-11-24 | 10X Genomics, Inc. | Single cell analysis of transposase accessible chromatin |
| EP3445876B1 (de) | 2017-05-26 | 2023-07-05 | 10X Genomics, Inc. | Einzelzellenanalyse von transposasezugänglichem chromatin |
| US10590244B2 (en) | 2017-10-04 | 2020-03-17 | 10X Genomics, Inc. | Compositions, methods, and systems for bead formation using improved polymers |
| US10837047B2 (en) | 2017-10-04 | 2020-11-17 | 10X Genomics, Inc. | Compositions, methods, and systems for bead formation using improved polymers |
| WO2019084043A1 (en) | 2017-10-26 | 2019-05-02 | 10X Genomics, Inc. | METHODS AND SYSTEMS FOR NUCLEIC ACID PREPARATION AND CHROMATIN ANALYSIS |
| WO2019084165A1 (en) | 2017-10-27 | 2019-05-02 | 10X Genomics, Inc. | METHODS AND SYSTEMS FOR SAMPLE PREPARATION AND ANALYSIS |
| SG11201913654QA (en) | 2017-11-15 | 2020-01-30 | 10X Genomics Inc | Functionalized gel beads |
| US10829815B2 (en) | 2017-11-17 | 2020-11-10 | 10X Genomics, Inc. | Methods and systems for associating physical and genetic properties of biological particles |
| WO2019108851A1 (en) | 2017-11-30 | 2019-06-06 | 10X Genomics, Inc. | Systems and methods for nucleic acid preparation and analysis |
| WO2019118355A1 (en) | 2017-12-12 | 2019-06-20 | 10X Genomics, Inc. | Systems and methods for single cell processing |
| CN111712579B (zh) | 2017-12-22 | 2024-10-15 | 10X基因组学有限公司 | 用于处理来自一个或多个细胞的核酸分子的系统和方法 |
| EP3752832A1 (de) | 2018-02-12 | 2020-12-23 | 10X Genomics, Inc. | Verfahren zur charakterisierung mehrerer analyten aus einzelnen zellen oder zellpopulationen |
| US11639928B2 (en) | 2018-02-22 | 2023-05-02 | 10X Genomics, Inc. | Methods and systems for characterizing analytes from individual cells or cell populations |
| WO2019169028A1 (en) | 2018-02-28 | 2019-09-06 | 10X Genomics, Inc. | Transcriptome sequencing through random ligation |
| SG11202009889VA (en) | 2018-04-06 | 2020-11-27 | 10X Genomics Inc | Systems and methods for quality control in single cell processing |
| US12454720B2 (en) | 2018-04-17 | 2025-10-28 | ChromaCode, Inc. | Methods and systems for multiplex analysis |
| WO2019217758A1 (en) | 2018-05-10 | 2019-11-14 | 10X Genomics, Inc. | Methods and systems for molecular library generation |
| US11932899B2 (en) | 2018-06-07 | 2024-03-19 | 10X Genomics, Inc. | Methods and systems for characterizing nucleic acid molecules |
| US11703427B2 (en) | 2018-06-25 | 2023-07-18 | 10X Genomics, Inc. | Methods and systems for cell and bead processing |
| US12203129B2 (en) | 2018-07-03 | 2025-01-21 | ChromaCode, Inc. | Formulations and signal encoding and decoding methods for massively multiplexed biochemical assays |
| US12188014B1 (en) | 2018-07-25 | 2025-01-07 | 10X Genomics, Inc. | Compositions and methods for nucleic acid processing using blocking agents |
| US20200032335A1 (en) | 2018-07-27 | 2020-01-30 | 10X Genomics, Inc. | Systems and methods for metabolome analysis |
| EP3830289A1 (de) | 2018-08-03 | 2021-06-09 | 10X Genomics, Inc. | Verfahren und systeme zur minimierung von strichcodeaustausch |
| WO2020041148A1 (en) | 2018-08-20 | 2020-02-27 | 10X Genomics, Inc. | Methods and systems for detection of protein-dna interactions using proximity ligation |
| US12065688B2 (en) | 2018-08-20 | 2024-08-20 | 10X Genomics, Inc. | Compositions and methods for cellular processing |
| US11459607B1 (en) | 2018-12-10 | 2022-10-04 | 10X Genomics, Inc. | Systems and methods for processing-nucleic acid molecules from a single cell using sequential co-partitioning and composite barcodes |
| US12169198B2 (en) | 2019-01-08 | 2024-12-17 | 10X Genomics, Inc. | Systems and methods for sample analysis |
| US11845983B1 (en) | 2019-01-09 | 2023-12-19 | 10X Genomics, Inc. | Methods and systems for multiplexing of droplet based assays |
| SG11202108788TA (en) | 2019-02-12 | 2021-09-29 | 10X Genomics Inc | Methods for processing nucleic acid molecules |
| US11467153B2 (en) | 2019-02-12 | 2022-10-11 | 10X Genomics, Inc. | Methods for processing nucleic acid molecules |
| WO2020167866A1 (en) | 2019-02-12 | 2020-08-20 | 10X Genomics, Inc. | Systems and methods for transposon loading |
| US11851683B1 (en) | 2019-02-12 | 2023-12-26 | 10X Genomics, Inc. | Methods and systems for selective analysis of cellular samples |
| US12275993B2 (en) | 2019-02-12 | 2025-04-15 | 10X Genomics, Inc. | Analysis of nucleic acid sequences |
| US12305239B2 (en) | 2019-02-12 | 2025-05-20 | 10X Genomics, Inc. | Analysis of nucleic acid sequences |
| WO2020167862A1 (en) | 2019-02-12 | 2020-08-20 | 10X Genomics, Inc. | Systems and methods for transfer of reagents between droplets |
| US11655499B1 (en) | 2019-02-25 | 2023-05-23 | 10X Genomics, Inc. | Detection of sequence elements in nucleic acid molecules |
| WO2020185791A1 (en) | 2019-03-11 | 2020-09-17 | 10X Genomics, Inc. | Systems and methods for processing optically tagged beads |
| US12235262B1 (en) | 2019-09-09 | 2025-02-25 | 10X Genomics, Inc. | Methods and systems for single cell protein analysis |
| US12449419B1 (en) | 2020-02-12 | 2025-10-21 | 10X Genomics, Inc. | Methods for detecting binding of peptide-MHC monomers to T cells |
| EP4104179A1 (de) | 2020-02-13 | 2022-12-21 | 10X Genomics, Inc. | Systeme und verfahren zur gemeinsamen interaktiven visualisierung von gen-expression und dna-chromatin-zugänglichkeit |
| US11851700B1 (en) | 2020-05-13 | 2023-12-26 | 10X Genomics, Inc. | Methods, kits, and compositions for processing extracellular molecules |
| US12480158B1 (en) | 2020-11-05 | 2025-11-25 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| US12084715B1 (en) | 2020-11-05 | 2024-09-10 | 10X Genomics, Inc. | Methods and systems for reducing artifactual antisense products |
| US12398262B1 (en) | 2021-01-22 | 2025-08-26 | 10X Genomics, Inc. | Triblock copolymer-based cell stabilization and fixation system and methods of use thereof |
| EP4298244A1 (de) | 2021-02-23 | 2024-01-03 | 10X Genomics, Inc. | Sonden-basierte analyse von nukleinsäuren und proteinen |
| DE102023119364A1 (de) | 2023-07-21 | 2025-01-23 | Giesecke+Devrient Currency Technology Gmbh | Sicherheitsmerkmal, Druckfarbe, Wertdokument und Wertdokumentsystem |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4552812A (en) * | 1981-07-01 | 1985-11-12 | Yeda Research And Development Company | Process for the production of polyacrolein microspheres and grafted microspheres |
| EP0230768A1 (de) * | 1985-12-20 | 1987-08-05 | Syntex (U.S.A.) Inc. | Teilchentrennungsverfahren |
| US5525516A (en) * | 1994-09-30 | 1996-06-11 | Eastman Chemical Company | Method for tagging petroleum products |
| US5573909A (en) * | 1992-05-13 | 1996-11-12 | Molecular Probes, Inc. | Fluorescent labeling using microparticles with controllable stokes shift |
| WO1997014028A2 (en) * | 1995-10-11 | 1997-04-17 | Luminex Corporation | Multiplexed analysis of clinical specimens apparatus and method |
| US5656750A (en) * | 1991-11-20 | 1997-08-12 | Polaroid Corporation | Processes for the preparation of squarylium dyes |
| US5723218A (en) * | 1990-04-16 | 1998-03-03 | Molecular Probes, Inc. | Dipyrrometheneboron difluoride labeled flourescent microparticles |
| WO1999019515A1 (en) * | 1997-10-14 | 1999-04-22 | Luminex Corporation | Precision fluorescently dyed particles and methods of making and using same |
| WO1999037814A1 (en) * | 1998-01-22 | 1999-07-29 | Luminex Corporation | Microparticles with multiple fluorescent signals |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4267234A (en) | 1978-03-17 | 1981-05-12 | California Institute Of Technology | Polyglutaraldehyde synthesis and protein bonding substrates |
| US4267235A (en) | 1979-03-19 | 1981-05-12 | California Institute Of Technology | Polyglutaraldehyde microspheres |
| US4530840A (en) | 1982-07-29 | 1985-07-23 | The Stolle Research And Development Corporation | Injectable, long-acting microparticle formulation for the delivery of anti-inflammatory agents |
| US4677138A (en) | 1983-10-19 | 1987-06-30 | Yeda Research And Development Co., Ltd. | High yield process for producing polyaldehyde microspheres |
| US5417986A (en) | 1984-03-16 | 1995-05-23 | The United States Of America As Represented By The Secretary Of The Army | Vaccines against diseases caused by enteropathogenic organisms using antigens encapsulated within biodegradable-biocompatible microspheres |
| US4677045A (en) | 1984-07-27 | 1987-06-30 | International Business Machines Corporation | Squarylium charge generating dye and electrophotographic photoconductor |
| US4665024A (en) | 1984-10-01 | 1987-05-12 | Becton, Dickinson And Company | Fluorescent gram stain |
| US5102872A (en) | 1985-09-20 | 1992-04-07 | Cetus Corporation | Controlled-release formulations of interleukin-2 |
| GB8601100D0 (en) | 1986-01-17 | 1986-02-19 | Cosmas Damian Ltd | Drug delivery system |
| EP0248531A3 (de) | 1986-05-02 | 1988-09-28 | Southern Research Institute | Verkapselte Nukleinsäuren |
| DE3784594T2 (de) | 1986-08-11 | 1994-01-05 | Innovata Biomed Ltd | Mikrokapseln enthaltende pharmazeutische Zusammensetzungen. |
| US5075109A (en) | 1986-10-24 | 1991-12-24 | Southern Research Institute | Method of potentiating an immune response |
| US4897268A (en) | 1987-08-03 | 1990-01-30 | Southern Research Institute | Drug delivery system and method of making the same |
| US4981625A (en) * | 1988-03-14 | 1991-01-01 | California Institute Of Technology | Monodisperse, polymeric microspheres produced by irradiation of slowly thawing frozen drops |
| US5237498A (en) | 1988-07-08 | 1993-08-17 | Hitachi, Ltd. | System and method for computing profits for individual entities of an entity group via use of means to retrieve and process data for specific entities |
| WO1991017772A1 (en) | 1990-05-16 | 1991-11-28 | Southern Research Institute | Controlled release dopamine and its use to stimulate nerve fiber growth |
| GB9016885D0 (en) | 1990-08-01 | 1990-09-12 | Scras | Sustained release pharmaceutical compositions |
| US5149543A (en) | 1990-10-05 | 1992-09-22 | Massachusetts Institute Of Technology | Ionically cross-linked polymeric microcapsules |
| US5293050A (en) | 1993-03-25 | 1994-03-08 | International Business Machines Corporation | Semiconductor quantum dot light emitting/detecting devices |
| US5565554A (en) | 1994-07-29 | 1996-10-15 | The Regents Of The University Of California | Dimeric fluorescent energy transfer dyes comprising asymmetric cyanine azole-indolenine chromophores |
| US5736330A (en) | 1995-10-11 | 1998-04-07 | Luminex Corporation | Method and compositions for flow cytometric determination of DNA sequences |
-
1999
- 1999-04-13 AU AU35555/99A patent/AU3555599A/en not_active Abandoned
- 1999-04-13 WO PCT/US1999/007993 patent/WO1999052708A1/en not_active Ceased
- 1999-04-13 EP EP99917429A patent/EP1079967A4/de not_active Withdrawn
Patent Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4552812A (en) * | 1981-07-01 | 1985-11-12 | Yeda Research And Development Company | Process for the production of polyacrolein microspheres and grafted microspheres |
| EP0230768A1 (de) * | 1985-12-20 | 1987-08-05 | Syntex (U.S.A.) Inc. | Teilchentrennungsverfahren |
| US5723218A (en) * | 1990-04-16 | 1998-03-03 | Molecular Probes, Inc. | Dipyrrometheneboron difluoride labeled flourescent microparticles |
| US5656750A (en) * | 1991-11-20 | 1997-08-12 | Polaroid Corporation | Processes for the preparation of squarylium dyes |
| US5573909A (en) * | 1992-05-13 | 1996-11-12 | Molecular Probes, Inc. | Fluorescent labeling using microparticles with controllable stokes shift |
| US5525516A (en) * | 1994-09-30 | 1996-06-11 | Eastman Chemical Company | Method for tagging petroleum products |
| US5525516B1 (en) * | 1994-09-30 | 1999-11-09 | Eastman Chem Co | Method for tagging petroleum products |
| WO1997014028A2 (en) * | 1995-10-11 | 1997-04-17 | Luminex Corporation | Multiplexed analysis of clinical specimens apparatus and method |
| WO1999019515A1 (en) * | 1997-10-14 | 1999-04-22 | Luminex Corporation | Precision fluorescently dyed particles and methods of making and using same |
| WO1999037814A1 (en) * | 1998-01-22 | 1999-07-29 | Luminex Corporation | Microparticles with multiple fluorescent signals |
Non-Patent Citations (6)
| Title |
|---|
| BIOTECHNOL BIOENG;BIOTECHNOLOGY AND BIOENGINEERING MAR 5 1997 JOHN WILEY & SONS INC, NEW YORK, NY, USA, vol. 53, no. 5, 5 March 1997 (1997-03-05), pages 459 - 469 * |
| DATABASE COMPENDEX [online] ENGINEERING INFORMATION, INC., NEW YORK, NY, US; BHATTACHARYYA BHUPATI R ET AL: "APPLICATION OF MONODISPERSE FUNCTIONAL AND FLUORESCENT LATEX PARTICLES", XP002232532, Database accession no. EIX78040005441 * |
| DATABASE COMPENDEX [online] ENGINEERING INFORMATION, INC., NEW YORK, NY, US; OKABE SATOSHI ET AL: "Uptake and release of inert fluorescence particles by mixed population biofilms", XP002232531, Database accession no. EIX97223597218 * |
| POLYM NEWS 1977, vol. 4, no. 3, 1977, pages 107 - 114 * |
| SCHARF R E ET AL: "PLATELET STORAGE LESIONS: ANALYSIS OF PLATELET MEMBRANE GLYCOPROTEINS AND PLATELET-DERIVED MICROPARTICLES BY FLUORESCENCE-ACTIVATED FLOW CYTOMETRY", TRANSFUSION SCIENCE, PERGAMON PRESS, OXFORD, GB, vol. 14, no. 2, 1993, pages 189 - 194, XP000998137, ISSN: 0955-3886 * |
| See also references of WO9952708A1 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO1999052708A1 (en) | 1999-10-21 |
| EP1079967A1 (de) | 2001-03-07 |
| AU3555599A (en) | 1999-11-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP1079967A4 (de) | Flüssige markierung mit fluorezierenden mikropartikeln | |
| AU138447S (en) | Adhesive-backed label | |
| PL325393A1 (en) | Label | |
| IL141759A0 (en) | Multihued labels | |
| PL342348A1 (en) | Label dispenser | |
| CA87769S (en) | Tag | |
| AU137192S (en) | Fluorescent lamp | |
| GB2355431B (en) | Label | |
| GB9822470D0 (en) | An improved liquid carrier | |
| EP1063680A4 (de) | Leuchtstofflampe | |
| GB2326866B (en) | Advertising label | |
| GB9822590D0 (en) | Self-adhesive labels | |
| HK1032770A (en) | Liquid labeling with fluorescent microparticles | |
| GB9909684D0 (en) | Labels and labelled containers | |
| GB9810969D0 (en) | Fluorescent lamps | |
| GB9901666D0 (en) | Intelligent adverts | |
| GB2356626B (en) | Label Support | |
| TW405605U (en) | Fluorescent self-adhered label | |
| CA84223S (en) | Signboard | |
| GB9815463D0 (en) | Labelling | |
| GB9802856D0 (en) | Adhesive-backed labels | |
| TW459493U (en) | Assembly illuminating label | |
| TW362805U (en) | Improved structure for illuminous labeling sign | |
| GB9818662D0 (en) | Signs | |
| CA81370S (en) | Label |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| 17P | Request for examination filed |
Effective date: 20001110 |
|
| AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
| AX | Request for extension of the european patent |
Free format text: AL PAYMENT 20001110;LT PAYMENT 20001110;LV PAYMENT 20001110;MK PAYMENT 20001110;RO PAYMENT 20001110;SI PAYMENT 20001110 |
|
| RIC1 | Information provided on ipc code assigned before grant |
Ipc: 7G 01N 33/28 B Ipc: 7G 01N 33/18 B Ipc: 7C 09K 11/06 A |
|
| A4 | Supplementary search report drawn up and despatched |
Effective date: 20030610 |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
| 18D | Application deemed to be withdrawn |
Effective date: 20030920 |
|
| REG | Reference to a national code |
Ref country code: HK Ref legal event code: WD Ref document number: 1032770 Country of ref document: HK |