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EP1069895A4 - Compositions contenant des acides lysophosphatidiques qui inhibent l'apoptose et leurs utilisations - Google Patents

Compositions contenant des acides lysophosphatidiques qui inhibent l'apoptose et leurs utilisations

Info

Publication number
EP1069895A4
EP1069895A4 EP99913956A EP99913956A EP1069895A4 EP 1069895 A4 EP1069895 A4 EP 1069895A4 EP 99913956 A EP99913956 A EP 99913956A EP 99913956 A EP99913956 A EP 99913956A EP 1069895 A4 EP1069895 A4 EP 1069895A4
Authority
EP
European Patent Office
Prior art keywords
compositions containing
inhibit apoptosis
lysophosphatidic acids
containing lysophosphatidic
acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99913956A
Other languages
German (de)
English (en)
Other versions
EP1069895A2 (fr
Inventor
John G Goddard
Donald H Picker
Samuil R Umansky
Steven Price
Jacobus C H M Wijkmans
Edward Andrew Boyd
Anthony David Baxter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LXR Biotechnology Inc
Original Assignee
LXR Biotechnology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LXR Biotechnology Inc filed Critical LXR Biotechnology Inc
Publication of EP1069895A2 publication Critical patent/EP1069895A2/fr
Publication of EP1069895A4 publication Critical patent/EP1069895A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP99913956A 1998-03-18 1999-03-17 Compositions contenant des acides lysophosphatidiques qui inhibent l'apoptose et leurs utilisations Withdrawn EP1069895A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7837598P 1998-03-18 1998-03-18
US78375P 1998-03-18
PCT/US1999/005943 WO1999047101A2 (fr) 1998-03-18 1999-03-17 Compositions contenant des acides lysophosphatidiques qui inhibent l'apoptose et leurs utilisations

Publications (2)

Publication Number Publication Date
EP1069895A2 EP1069895A2 (fr) 2001-01-24
EP1069895A4 true EP1069895A4 (fr) 2002-07-31

Family

ID=22143648

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99913956A Withdrawn EP1069895A4 (fr) 1998-03-18 1999-03-17 Compositions contenant des acides lysophosphatidiques qui inhibent l'apoptose et leurs utilisations

Country Status (3)

Country Link
EP (1) EP1069895A4 (fr)
AU (1) AU3191599A (fr)
WO (1) WO1999047101A2 (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6495532B1 (en) 1997-03-19 2002-12-17 Sky High, Llc Compositions containing lysophosphotidic acids which inhibit apoptosis and uses thereof
US6380177B1 (en) 1999-06-25 2002-04-30 Atairgin Technologies, Inc. LPA analogs as agonists of the Edg2 LPA receptor
WO2001012838A2 (fr) * 1999-08-18 2001-02-22 Atairgin Technologies, Inc. Composes modulateurs de l'activite d'un recepteur d'acide lysophosphatidique (lpa)
AU6595900A (en) * 1999-08-18 2001-03-13 Kyowa Hakko Kogyo Co. Ltd. Hair growth stimulants
AU2580801A (en) * 1999-12-14 2001-06-25 Sky High, Llc Phospholipid compositions as anti-inflammation agents
US6492334B1 (en) 1999-12-30 2002-12-10 Robert James Generale Tri-compound analgesic for treating inflammation and pain
US20030130237A1 (en) * 2000-03-17 2003-07-10 Miller Duane D. LPA receptor agonists and antagonists and methods of use
WO2001071022A2 (fr) * 2000-03-17 2001-09-27 The University Of Tennessee Research Corporation Agonistes et antagonistes du recepteur lpa et procedes d'utilisation de ces derniers
CA2371398A1 (fr) * 2001-02-16 2002-08-16 Kyowa Hakko Kogyo Co., Ltd. Agent pour la pousse des cheveux
JP4815063B2 (ja) * 2001-04-13 2011-11-16 きみ子 室伏 環状ホスファチジン酸を含むグリア細胞の増殖、分化及び／又は生存の促進のための薬剤
JP4836345B2 (ja) * 2001-04-13 2011-12-14 きみ子 室伏 環状ホスファチジン酸誘導体を含む神経細胞の生存促進剤
JP4162927B2 (ja) 2002-06-11 2008-10-08 きみ子 室伏 カルバ環状ホスファチジン酸誘導体
DK1678096T3 (da) * 2003-10-09 2012-04-23 Univ Tennessee Res Foundation LPA-receptoragonister og -antagonister og anvendelsesfremgangsmåder
US7820703B2 (en) 2004-05-06 2010-10-26 University Of Virginia Patent Foundation Lysophosphatidic acid receptor selective antagonists
US20070078111A1 (en) * 2005-07-19 2007-04-05 Gabor Tigyi LPA2 receptor agonist inhibitors of CFTR
EP2183258A2 (fr) * 2007-08-01 2010-05-12 Centre National de la Recherche Scientifique (CNRS) Dérivés de l'acide thiophosphi(o)nique et leurs applications thérapeutiques

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4504409A (en) * 1981-12-16 1985-03-12 Kao Corporation Emulsifying composition
JPH05311200A (ja) * 1992-05-13 1993-11-22 Sanyo Chem Ind Ltd アルカリ性洗浄剤
WO1995020967A1 (fr) * 1994-02-04 1995-08-10 Cell Therapeutics, Inc. Composition de cicatrisation, de croissance des neurones et de vascularisation
US5624672A (en) * 1993-11-30 1997-04-29 Lxr Biotechnology Inc. Compositions which inhibit apoptosis, methods of purifying the compositions and uses thereof
WO1998041213A1 (fr) * 1997-03-19 1998-09-24 Lxr Biotechnology Inc. Compositions contenant des acides lysophosphotidiques inhibant l'apoptose, et leurs utilisations
WO1999008514A1 (fr) * 1997-08-20 1999-02-25 Lxr Biotechnology, Inc. Compositions contenant du polyethylene glycol et leurs utilisations

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS492266B1 (fr) * 1970-06-06 1974-01-19
JPS57167364A (en) * 1981-04-07 1982-10-15 Sankin Kogyo Kk Adhesive for hard tissue of human body
JPS5810559A (ja) * 1981-07-10 1983-01-21 Ajinomoto Co Inc α−クロル−β−チオスルフオ−プロピオン酸エステル塩の製造法
JPS63265972A (ja) * 1987-04-24 1988-11-02 Denki Kagaku Kogyo Kk 変性塩化ビニル樹脂溶液
US4938961A (en) 1989-04-28 1990-07-03 Geoffrey Collins Organ preservation solution containing pokyethylene gycol and method of performing cardioplegia
US6071528A (en) * 1997-02-19 2000-06-06 Ultradent Products, Inc. Adhesive antimicrobial and/or reparative dentin stimulating dental compositions and methods for forming and using such compositions

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4504409A (en) * 1981-12-16 1985-03-12 Kao Corporation Emulsifying composition
JPH05311200A (ja) * 1992-05-13 1993-11-22 Sanyo Chem Ind Ltd アルカリ性洗浄剤
US5624672A (en) * 1993-11-30 1997-04-29 Lxr Biotechnology Inc. Compositions which inhibit apoptosis, methods of purifying the compositions and uses thereof
US5635187A (en) * 1993-11-30 1997-06-03 Lxr Biotechnology Inc. Compositions which inhibit apoptosis, methods of purifying the compositions and uses thereof
WO1995020967A1 (fr) * 1994-02-04 1995-08-10 Cell Therapeutics, Inc. Composition de cicatrisation, de croissance des neurones et de vascularisation
WO1998041213A1 (fr) * 1997-03-19 1998-09-24 Lxr Biotechnology Inc. Compositions contenant des acides lysophosphotidiques inhibant l'apoptose, et leurs utilisations
WO1999008514A1 (fr) * 1997-08-20 1999-02-25 Lxr Biotechnology, Inc. Compositions contenant du polyethylene glycol et leurs utilisations

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
DANG QUOC QUAN ET AL: "Synthesis and identification of bis (diacylglycero) phosphoric acid and bis (monoacylglycero) phosphoric acid", LIPIDS (1982), 17(11), 798-802, XP001022836 *
HOLBROOK, P. G. ET AL: "Bis(monoacylglycero)phosphate from PC12 cells, a phospholipid that can comigrate with phosphatidic acid: molecular species analysis by fast atom bombardment mass spectrometry", BIOCHIM. BIOPHYS. ACTA (1992), 1125(3), 330-4, XP001022857 *
PATENT ABSTRACTS OF JAPAN vol. 018, no. 128 (C - 1174) 2 March 1994 (1994-03-02) *
QUOC QUAN DANG ET AL: "Synthesis and stereochemical study of some biologically relevant phosphoglycerides: dicarboxylic phosphatidylcholines and bis(diacylglycero)phosphoric acids", PHOSPHORUS SULFUR (1983), 18(1-2-3), 377-80, XP001022829 *
QUOC QUAN DANG ET AL: "Synthesis of labeled stereoisomers of bis(diacylglycero)phosphates and lyso derivatives", BIOCHIM. BIOPHYS. ACTA (1985), 834(1), 124-9, XP001022491 *
See also references of WO9947101A2 *

Also Published As

Publication number Publication date
WO1999047101A2 (fr) 1999-09-23
WO1999047101A3 (fr) 1999-11-25
AU3191599A (en) 1999-10-11
EP1069895A2 (fr) 2001-01-24

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