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EP0934025B1 - Detachable multidiameter vasoocclusive coil - Google Patents

Detachable multidiameter vasoocclusive coil Download PDF

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Publication number
EP0934025B1
EP0934025B1 EP97912966A EP97912966A EP0934025B1 EP 0934025 B1 EP0934025 B1 EP 0934025B1 EP 97912966 A EP97912966 A EP 97912966A EP 97912966 A EP97912966 A EP 97912966A EP 0934025 B1 EP0934025 B1 EP 0934025B1
Authority
EP
European Patent Office
Prior art keywords
coil
diameter
distal end
proximal end
vessel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
EP97912966A
Other languages
German (de)
French (fr)
Other versions
EP0934025A1 (en
Inventor
Christopher G. M. Ken
Abhijit Acharya
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boston Scientific Ltd Barbados
Original Assignee
Boston Scientific Ltd Barbados
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boston Scientific Ltd Barbados filed Critical Boston Scientific Ltd Barbados
Publication of EP0934025A1 publication Critical patent/EP0934025A1/en
Application granted granted Critical
Publication of EP0934025B1 publication Critical patent/EP0934025B1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12099—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
    • A61B17/12109—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12099—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
    • A61B17/12109—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel
    • A61B17/12113—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel within an aneurysm
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/1214—Coils or wires
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B2017/1205—Introduction devices

Definitions

  • This invention is in the field of vasoocclusion devices. More particularly it relates to a helical vasoocclusion coil one end of which is adapted to be detachably connected to a wire and in which the helix winding at that end has a smaller diameter than the adjacent windings.
  • Vasoocclusion devices are surgical instruments that are placed within vessels, typically via a catheter, to block the vessel or to fill a vascular cavity such as an aneurysm.
  • One type of vasoocclusion device is in the form of a helical wire coil. See US-A-4,994,069.
  • the coil may be placed at the desired site in several ways. One involves loading the coil into the lumen of a catheter whose distal end is located at the site. The coil is then advanced through the catheter lumen using a pusher and expelled from the distal end of the catheter. Another involves detachably coupling the coil to the distal end of a wire, advancing the assembly to the site using a catheter, and uncoupling the coil from the wire at the site.
  • US-A-5,234,437; 5,250,071; 5,261,916; 5,304,195; 5,312,415; and 5,350,397 describe coils that are detachably coupled to a wire.
  • Detachable coils carry a member on their proximal end that detachably engages or interlocks with a member on the distal end of the wire.
  • a problem experienced with such coils is that the member carried on the coil is oriented tangentially to the helical diameter of the coil. As such, when the coil is decoupled, the member extends tangentially outwardly from the helix diameter and may engage the vessel wall. (See Figure 1 of the drawings) Such engagement may injure or even perforate the vessel wall.
  • a principal object of this invention is to provide a detachable helical vasoocclusive coil in which the member that attaches to the wire is not oriented tangentially to the diameter of the coil. Accordingly, the coils of this invention are less likely to injure the vessel wall.
  • US-A-5,261 916 discloses a pusher-vasoocclusive coil assembly in which the coil has an enlarged member at its proximal end and the pusher has a keyway at its distal end that receives the enlarged member in interlocking engagement.
  • the precharacterising portions of claims 1 and 3 are based on the disclosure of this reference.
  • a soft flexible helical vasoocclusion coil for use with a wire having a distal end, said coil having:
  • Figures 2 and 3 depict an embodiment, generally designated 10, of the invention coil.
  • Embodiment 10 is shown in its relaxed, helical configuration.
  • helical vasoocclusive coils are typically made of materials that have shape memories and can be deformed into an expanded, essentially linear shape for loading and advancement through a catheter to the site to be occluded. Once they are deployed from the catheter they assume a relaxed helical configuration, such as shown in Figure 3.
  • Coil 10 is composed of a multiplicity of windings 11 and has a distal end 12 and a proximal end 13.
  • the windings of coil 10 will typically be made of a metal such as platinum, gold, rhodium, rhenium, palladium, tungsten and the like or alloys of such metals. These metals have significant radiopacity and their alloys may be tailored to provide desired degrees of stiffness and flexibility.
  • the windings may be made of other suitable biocompatible materials such as polymers or composites of metals and polymers.
  • the cross-section of the windings of the coil 10 is circular, windings having other cross-sectional shapes, e.g. elliptical, trapezoidal, rhombic, rectangular, and square, may be used.
  • Circular cross-sectional windings will typically have a diameter of about 0.01 to about 0.50 mm.
  • the diameter of the helix, D ( Figure 3) formed by the windings will normally be in the range of about 0.2 mm to about 30 mm.
  • the diameter of the helix will typically be in the range of 2.0 to 20 mm.
  • the pitch of the windings may be uniform, as shown in Figure 3, or may vary over a portion or the entire length of the coil.
  • the axial length of the coil will usually be in the range of 0.5 to 100 cm, more usually 2 to 40 cm.
  • the coil will usually have 10 to 75 windings per cm, more usually 10 to 40 windings per cm. It will be appreciated that the above-described dimensions are not critical and that dimensions that are suitable for occluding vascular sites within the human body are intended.
  • the windings of the main body 14 of the coil form a helix of diameter D, whereas the proximal-most and distal-most windings have a diameter d that is smaller than D.
  • the proximal and distal ends 12,13, respectively, of the coil are located radially inwardly of the helix of main body 14 ( Figure 2) rather than being located tangentially to that helix ( Figure 1). Such positioning of the ends make the ends less likely to injure the vessel wall.
  • the proximal end 13 of the coil has a slotted member that is adapted to detachably couple to a mating member on the distal end of an elongated wire (not shown).
  • Alternative mechanical coupling members are shown in US-A-5,234,437; 5,250,071; 5,261,916; 5,304,195; 5,312,415 and 5,350,397.
  • the coil may have fibers attached to it to facilitate embolization. See US-A-5,304,194; 5,476,472 and 5,382,259. Other modifications of the above described modes for carrying out the invention that are considered obvious or equivalent by those of skill in the medical device art and related arts are intended to be within the scope of the following claims.

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  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Reproductive Health (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Surgical Instruments (AREA)

Abstract

A vasoocclusive helical coil having a proximal end that carries a coupling member for attaching the coil to the distal end of a wire and a proximal winding that has a smaller diameter than adjacent windings whereby the proximal end of the coil is positioned radially inwardly of the main body of the coil.

Description

  • This invention is in the field of vasoocclusion devices. More particularly it relates to a helical vasoocclusion coil one end of which is adapted to be detachably connected to a wire and in which the helix winding at that end has a smaller diameter than the adjacent windings.
  • Vasoocclusion devices are surgical instruments that are placed within vessels, typically via a catheter, to block the vessel or to fill a vascular cavity such as an aneurysm. One type of vasoocclusion device is in the form of a helical wire coil. See US-A-4,994,069. The coil may be placed at the desired site in several ways. One involves loading the coil into the lumen of a catheter whose distal end is located at the site. The coil is then advanced through the catheter lumen using a pusher and expelled from the distal end of the catheter. Another involves detachably coupling the coil to the distal end of a wire, advancing the assembly to the site using a catheter, and uncoupling the coil from the wire at the site. US-A-5,234,437; 5,250,071; 5,261,916; 5,304,195; 5,312,415; and 5,350,397 describe coils that are detachably coupled to a wire.
  • Detachable coils carry a member on their proximal end that detachably engages or interlocks with a member on the distal end of the wire. A problem experienced with such coils is that the member carried on the coil is oriented tangentially to the helical diameter of the coil. As such, when the coil is decoupled, the member extends tangentially outwardly from the helix diameter and may engage the vessel wall. (See Figure 1 of the drawings) Such engagement may injure or even perforate the vessel wall.
  • A principal object of this invention is to provide a detachable helical vasoocclusive coil in which the member that attaches to the wire is not oriented tangentially to the diameter of the coil. Accordingly, the coils of this invention are less likely to injure the vessel wall.
  • US-A-5,261 916 discloses a pusher-vasoocclusive coil assembly in which the coil has an enlarged member at its proximal end and the pusher has a keyway at its distal end that receives the enlarged member in interlocking engagement. The precharacterising portions of claims 1 and 3 are based on the disclosure of this reference.
  • According to a first aspect of the present invention there is provided a soft flexible helical vasoocclusion coil for use with a wire having a distal end, said coil having:
  • a proximal end adapted to detachably couple to the distal end of the wire; and
  • a distal end;
  • said helical vasoocclusion coil being for occluding a vessel or a cavity when placed within said vessel or cavity and comprising a multiplicity of windings having a first diameter immediately adjacent said distal end and said proximal end;
    •    characterised in that said coil is further wound into a second diameter, smaller than said first diameter, at said proximal end whereby said proximal end is positioned radially inwardly of said immediately adjacent first diameter.
       According to a second aspect of the present invention there is provided an assembly for use in occluding a vessel or a cavity within a vessel, comprising:
    • (a) an elongated wire having a distal end that carries a first coupling member; and
    • (b) a soft flexible helical vasoocclusion coil having:
    • a proximal end that carries a second coupling member that is detachably coupled to the first coupling member, and
    • a distal end;
    • said coil being for occluding a vessel or cavity within a vessel when placed within said vessel or cavity and comprising a multiplicity of windings having a first diameter immediately adjacent said proximal end and said distal end;
       characterised in that said coil is further wound into a second diameter, smaller than said first diameter, at said proximal end whereby the second coupling member is positioned radially inwardly of said immediately adjacent first diameter.
  • An embodiment of a preferred device in accordance with the present invention will now be described, by way of example only, with reference to the following drawings, described below.
  • Figure 1 is an elevational view of a prior art coil.
  • Figure 2 is an elevational end view of one embodiment of the invention.
  • Figure 3 is an elevational partial side view of the coil of Figure 2.
  • Figures 2 and 3 depict an embodiment, generally designated 10, of the invention coil. Embodiment 10 is shown in its relaxed, helical configuration. As described in the art discussed in the Background section above, helical vasoocclusive coils are typically made of materials that have shape memories and can be deformed into an expanded, essentially linear shape for loading and advancement through a catheter to the site to be occluded. Once they are deployed from the catheter they assume a relaxed helical configuration, such as shown in Figure 3.
  • Coil 10 is composed of a multiplicity of windings 11 and has a distal end 12 and a proximal end 13. The windings of coil 10 will typically be made of a metal such as platinum, gold, rhodium, rhenium, palladium, tungsten and the like or alloys of such metals. These metals have significant radiopacity and their alloys may be tailored to provide desired degrees of stiffness and flexibility. The windings may be made of other suitable biocompatible materials such as polymers or composites of metals and polymers.
  • While the cross-section of the windings of the coil 10 is circular, windings having other cross-sectional shapes, e.g. elliptical, trapezoidal, rhombic, rectangular, and square, may be used. Circular cross-sectional windings will typically have a diameter of about 0.01 to about 0.50 mm. Correspondingly, the diameter of the helix, D (Figure 3), formed by the windings will normally be in the range of about 0.2 mm to about 30 mm. For neurovascular use the diameter of the helix will typically be in the range of 2.0 to 20 mm. The pitch of the windings may be uniform, as shown in Figure 3, or may vary over a portion or the entire length of the coil. The axial length of the coil will usually be in the range of 0.5 to 100 cm, more usually 2 to 40 cm. The coil will usually have 10 to 75 windings per cm, more usually 10 to 40 windings per cm. It will be appreciated that the above-described dimensions are not critical and that dimensions that are suitable for occluding vascular sites within the human body are intended.
  • As shown in Figure 3, the windings of the main body 14 of the coil form a helix of diameter D, whereas the proximal-most and distal-most windings have a diameter d that is smaller than D. As a result, the proximal and distal ends 12,13, respectively, of the coil are located radially inwardly of the helix of main body 14 (Figure 2) rather than being located tangentially to that helix (Figure 1). Such positioning of the ends make the ends less likely to injure the vessel wall. As seen in Figures 2 and 3, the proximal end 13 of the coil has a slotted member that is adapted to detachably couple to a mating member on the distal end of an elongated wire (not shown). Alternative mechanical coupling members are shown in US-A-5,234,437; 5,250,071; 5,261,916; 5,304,195; 5,312,415 and 5,350,397.
  • While not shown in the drawings, the coil may have fibers attached to it to facilitate embolization. See US-A-5,304,194; 5,476,472 and 5,382,259. Other modifications of the above described modes for carrying out the invention that are considered obvious or equivalent by those of skill in the medical device art and related arts are intended to be within the scope of the following claims.

Claims (3)

  1. A soft flexible helical vasoocclusion coil (10) for use with a wire having a distal end, said coil having:
    a proximal end (13) adapted to detachably couple to the distal end of the wire; and
    a distal end (12);
    said helical vasoocclusion coil (10) being for occluding a vessel or a cavity when placed within said vessel or cavity and comprising a multiplicity of windings (11) having a first diameter (D) immediately adjacent said distal end (12) and said proximal end (13);
       characterised in that said coil is further wound into a second diameter (d), smaller than said first diameter, at said proximal end (13) whereby said proximal end is positioned radially inwardly of said immediately adjacent first diameter.
  2. The coil of claim 1, wherein said proximal end (13) has a coupling member that detachably interlocks with the distal end of the wire.
  3. An assembly for use in occluding a vessel or a cavity within a vessel, comprising:
    (a) an elongated wire having a distal end that carries a first coupling member; and
    (b) a soft flexible helical vasoocclusion coil (10) having:
    a proximal end (13) that carries a second coupling member that is detachably coupled to the first coupling member, and
    a distal end (12);
    said coil (10) being for occluding a vessel or cavity within a vessel when placed within said vessel or cavity and comprising a multiplicity of windings (11) having a first diameter (D) immediately adjacent said proximal end (13) and said distal end (12);
       characterised in that said coil (10) is further wound into a second diameter (d), smaller than said first diameter, at said proximal end (13) whereby the second coupling member is positioned radially inwardly of said immediately adjacent first diameter.
EP97912966A 1996-10-25 1997-10-24 Detachable multidiameter vasoocclusive coil Expired - Lifetime EP0934025B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/736,896 US6984240B1 (en) 1996-10-25 1996-10-25 Detachable multidiameter vasoocclusive coil
PCT/US1997/019517 WO1998017183A1 (en) 1996-10-25 1997-10-24 Detachable multidiameter vasoocclusive coil
US736896 2000-12-14

Publications (2)

Publication Number Publication Date
EP0934025A1 EP0934025A1 (en) 1999-08-11
EP0934025B1 true EP0934025B1 (en) 2004-06-16

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EP97912966A Expired - Lifetime EP0934025B1 (en) 1996-10-25 1997-10-24 Detachable multidiameter vasoocclusive coil

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US (2) US6984240B1 (en)
EP (1) EP0934025B1 (en)
JP (1) JP2001502221A (en)
AU (1) AU5002597A (en)
DE (1) DE69729572T2 (en)
WO (1) WO1998017183A1 (en)

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Also Published As

Publication number Publication date
EP0934025A1 (en) 1999-08-11
US6984240B1 (en) 2006-01-10
DE69729572D1 (en) 2004-07-22
DE69729572T2 (en) 2005-06-09
US20050033350A1 (en) 2005-02-10
AU5002597A (en) 1998-05-15
JP2001502221A (en) 2001-02-20
WO1998017183A1 (en) 1998-04-30

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