EP0904271A4 - 5,6,7,8-tetrahydropyrido [2,3-d] PYRIMIDINE - Google Patents

5,6,7,8-tetrahydropyrido [2,3-d] PYRIMIDINE

Info

Publication number: EP0904271A4
Authority: EP; European Patent Office
Prior art keywords: tetrahydropyrido; pyrimidine
Prior art date: 1996-05-01
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP96931596A

Other languages

German (de)

French (fr)

Other versions

EP0904271A1 (en

Inventor

Edward C Taylor

Chuan Shih

Koo Lee

Lynn S Gossett

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Eli Lilly and Co

Princeton University

Original Assignee

Eli Lilly and Co

Princeton University

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-05-01

Filing date

1996-09-17

Publication date

2002-01-23

1996-09-17 Application filed by Eli Lilly and Co, Princeton University filed Critical Eli Lilly and Co

1999-03-31 Publication of EP0904271A1 publication Critical patent/EP0904271A1/en

2002-01-23 Publication of EP0904271A4 publication Critical patent/EP0904271A4/en

Status Withdrawn legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Genetics & Genomics (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

EP96931596A 1996-05-01 1996-09-17 5,6,7,8-tetrahydropyrido [2,3-d] PYRIMIDINE Withdrawn EP0904271A4 (en)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US64066996A	1996-05-01	1996-05-01
US2117496P	1996-05-01	1996-05-01
US21174P		1996-05-01
PCT/US1996/014822 WO1997041115A1 (en)	1996-05-01	1996-09-17	5,6,7,8-TETRAHYDROPYRIDO[2,3-d]PYRIMIDINES

Publications (2)

Publication Number	Publication Date
EP0904271A1 EP0904271A1 (en)	1999-03-31
EP0904271A4 true EP0904271A4 (en)	2002-01-23

Family

ID=26694360

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP96931596A Withdrawn EP0904271A4 (en)	1996-05-01	1996-09-17	5,6,7,8-tetrahydropyrido [2,3-d] PYRIMIDINE

Country Status (5)

Country	Link
EP (1)	EP0904271A4 (en)
JP (1)	JP2001524927A (en)
AU (1)	AU7073296A (en)
CA (1)	CA2251813A1 (en)
WO (1)	WO1997041115A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2004113337A1 (en) *	2003-06-25	2004-12-29	Pfizer Inc.	Convergent synthesis of a garft inhibitor containing a methyl substitute thiophene core and a tetrahydropyrido`2,3-d! pyrimidine ring system and intermediates therefor
AU2004312530A1 (en) *	2003-12-29	2005-07-21	Sepracor Inc.	Pyrrole and pyrazole DAAO inhibitors

Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0343801A2 (en) *	1988-05-25	1989-11-29	The Trustees Of Princeton University	N-(5,6,7,8-tetrahydropyrido(2,3-D)pyrimidin-6-yl-alkanoyl)-glutamic acid derivatives
US5354751A (en) *	1992-03-03	1994-10-11	Sri International	Heteroaroyl 10-deazaamino-pterine compounds and use for rheumatoid arthritis

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4895946A (en) *	1987-10-26	1990-01-23	The Trustees Of Princeton University	Process for the preparation of fused pyridine compounds
US5008391A (en) *	1989-07-07	1991-04-16	Eli Lilly And Company	Enantioselective synthesis of antifolates
US5508281A (en) *	1991-04-08	1996-04-16	Duquesne University Of The Holy Ghost	Derivatives of pyrido [2,3-d] and [3,2-d] pyrimidine and methods of using these derivatives
US5536724A (en) *	1992-03-03	1996-07-16	Sri International	Antiinflammatory and antineoplastic 5-deazaaminopterins and 5,10-dideazaaminopterins

1996
- 1996-09-17 JP JP53884097A patent/JP2001524927A/en not_active Ceased
- 1996-09-17 WO PCT/US1996/014822 patent/WO1997041115A1/en not_active Ceased
- 1996-09-17 EP EP96931596A patent/EP0904271A4/en not_active Withdrawn
- 1996-09-17 CA CA002251813A patent/CA2251813A1/en not_active Abandoned
- 1996-09-17 AU AU70732/96A patent/AU7073296A/en not_active Abandoned

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0343801A2 (en) *	1988-05-25	1989-11-29	The Trustees Of Princeton University	N-(5,6,7,8-tetrahydropyrido(2,3-D)pyrimidin-6-yl-alkanoyl)-glutamic acid derivatives
US5354751A (en) *	1992-03-03	1994-10-11	Sri International	Heteroaroyl 10-deazaamino-pterine compounds and use for rheumatoid arthritis

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO9741115A1 *

Also Published As

Publication number	Publication date
CA2251813A1 (en)	1997-11-06
WO1997041115A1 (en)	1997-11-06
AU7073296A (en)	1997-11-19
EP0904271A1 (en)	1999-03-31
JP2001524927A (en)	2001-12-04

Publication	Publication Date	Title
NO20021694D0 (en)	2002-04-10	Pyrazolo [4,3-d] pyrimidine
DK1087971T3 (en)	2004-10-11	Pyrrolo [2,3-d] pyrimidine compounds
NO20006453D0 (en)	2000-12-18	Pyrrolo (2,3-d) pyrimidine
DE69804273D1 (en)	2002-04-25	5h-thiazolo [3,2-a] pyrimidine derivatives
IS6383A (en)	2002-05-14	Pyrrolo [2,3-d] pyrimidine compounds
DK1210349T3 (en)	2003-05-19	Pyrazolo [4,3-d] pyrimidines
NO995033D0 (en)	1999-10-15	6,7-disubstituted-4-aminopyrido [2,3-D] pyrimidine
NO995035D0 (en)	1999-10-15	5,6,7-trisubstituted-4-aminopyrido [2,3-D] pyrimidine
EP0904271A4 (en)	2002-01-23	5,6,7,8-tetrahydropyrido [2,3-d] PYRIMIDINE
DE50106542D1 (en)	2005-07-21	SUBSTITUTED 3,4-DIHYDRO-PYRIDO [1,2-A] PYRIMIDINES
AU3500997A (en)	1998-01-14	5,6,7,8-tetrahydropyrido{2,3-d}pyrimidine derivatives
HK1019333A (en)	2000-02-03	5, 6, 7, 8-tetrahydropyrido[2, 3-d]pyrimidines

Legal Events

Date	Code	Title	Description
1999-02-12	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
1999-03-31	17P	Request for examination filed	Effective date: 19981026
1999-03-31	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
2002-01-23	A4	Supplementary search report drawn up and despatched	Effective date: 20011212
2002-01-23	AK	Designated contracting states	Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
2002-05-02	17Q	First examination report despatched	Effective date: 20020318
2004-03-27	GRAP	Despatch of communication of intention to grant a patent	Free format text: ORIGINAL CODE: EPIDOSNIGR1
2005-01-14	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2005-03-02	18D	Application deemed to be withdrawn	Effective date: 20040811
2006-04-28	REG	Reference to a national code	Ref country code: HK Ref legal event code: WD Ref document number: 1019333 Country of ref document: HK
2007-11-14	RTI1	Title (correction)	Free format text: 5,6,7,8-TETRAHYDROPYRIDO??2,3-D PYRIMIDINES