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EP0998280A4 - Composes de glucide presentant une structure d'echafaudage et banques les contenant - Google Patents

Composes de glucide presentant une structure d'echafaudage et banques les contenant

Info

Publication number
EP0998280A4
EP0998280A4 EP19980924946 EP98924946A EP0998280A4 EP 0998280 A4 EP0998280 A4 EP 0998280A4 EP 19980924946 EP19980924946 EP 19980924946 EP 98924946 A EP98924946 A EP 98924946A EP 0998280 A4 EP0998280 A4 EP 0998280A4
Authority
EP
European Patent Office
Prior art keywords
libraries
scaffold compounds
carbohydrate scaffold
carbohydrate
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19980924946
Other languages
German (de)
English (en)
Other versions
EP0998280A1 (fr
Inventor
Tin Yau Chan
Michael J Sofia
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aeolus Pharmaceuticals Inc
Original Assignee
Incara Pharmaceuticals Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incara Pharmaceuticals Corp filed Critical Incara Pharmaceuticals Corp
Publication of EP0998280A1 publication Critical patent/EP0998280A1/fr
Publication of EP0998280A4 publication Critical patent/EP0998280A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Saccharide Compounds (AREA)
  • Furan Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP19980924946 1997-05-29 1998-05-28 Composes de glucide presentant une structure d'echafaudage et banques les contenant Withdrawn EP0998280A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4794697P 1997-05-29 1997-05-29
US47946P 1997-05-29
PCT/US1998/010867 WO1998053813A1 (fr) 1997-05-29 1998-05-28 Composes de glucide presentant une structure d'echafaudage et banques les contenant

Publications (2)

Publication Number Publication Date
EP0998280A1 EP0998280A1 (fr) 2000-05-10
EP0998280A4 true EP0998280A4 (fr) 2002-11-06

Family

ID=21951894

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19980924946 Withdrawn EP0998280A4 (fr) 1997-05-29 1998-05-28 Composes de glucide presentant une structure d'echafaudage et banques les contenant

Country Status (4)

Country Link
EP (1) EP0998280A4 (fr)
JP (1) JP2002502393A (fr)
AU (1) AU7700098A (fr)
WO (1) WO1998053813A1 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60044846D1 (de) 1999-03-05 2010-09-30 Massachusetts Inst Technology Linker zur synthese von oligosacchariden auf festträgern
AUPS143402A0 (en) * 2002-03-28 2002-05-09 Alchemia Pty Ltd Anomeric derivatives of monosaccharides
AUPS213802A0 (en) 2002-05-03 2002-06-06 Alchemia Pty Ltd Disaccharides for drug discovery
AU2003266863B2 (en) * 2002-10-17 2007-03-08 Vast Bioscience Pty Ltd Carbohydrate based anti-bacterials
AU2002952121A0 (en) 2002-10-17 2002-10-31 Alchemia Limited Novel carbohydrate based anti-bacterials
US7951789B2 (en) 2006-12-28 2011-05-31 Idenix Pharmaceuticals, Inc. Compounds and pharmaceutical compositions for the treatment of viral infections
EP2552203B1 (fr) 2010-04-01 2017-03-22 Idenix Pharmaceuticals LLC. Composés et compositions pharmaceutiques pour le traitement d'infections virales
US9243025B2 (en) 2011-03-31 2016-01-26 Idenix Pharmaceuticals, Llc Compounds and pharmaceutical compositions for the treatment of viral infections

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07242684A (ja) * 1994-03-02 1995-09-19 Japan Tobacco Inc 新規なグルクロン酸化合物
US5556836A (en) * 1993-11-08 1996-09-17 Asta Medica Aktiengesellschaft Use of D-glucopyranuronic acids and their derivatives for incorporation in pharmacologically active peptides and their salts

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5221754A (en) * 1989-06-09 1993-06-22 Research Corporation Technologies, Inc. Reagents for rapid peptide synthesis
RU2134693C1 (ru) * 1993-02-23 1999-08-20 Зе Трастис оф Принстон Юниверсити Способы формирования гликозидных связей, химическая композиция, гликозид и гликозидная библиотека
US5773512A (en) * 1994-12-15 1998-06-30 Smithkline Beecham Corp. Compounds and methods
AU697920B2 (en) * 1994-07-26 1998-10-22 Scripps Research Institute, The Soluble combinatorial libraries
US5756712A (en) * 1997-01-23 1998-05-26 E. I. Du Pont De Nemours And Company Peptidodisaccharides as oligosaccharide mimetics

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5556836A (en) * 1993-11-08 1996-09-17 Asta Medica Aktiengesellschaft Use of D-glucopyranuronic acids and their derivatives for incorporation in pharmacologically active peptides and their salts
JPH07242684A (ja) * 1994-03-02 1995-09-19 Japan Tobacco Inc 新規なグルクロン酸化合物

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, vol. 111, no. 15, 1989, Columbus, Ohio, US; abstract no. 134731, page 818; column left; XP002217788 *
GOEBEL M ET AL: "Beyond Peptide and Nucleic Acid Combinatorial Libraries-Applying Unions of Multicomponent Reactions towards the Generation of Carbohydrate Combinatorial Libraries", TETRAHEDRON LETTERS, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 36, no. 34, 1 August 1995 (1995-08-01), pages 6043 - 6046, XP004027444, ISSN: 0040-4039 *
HECKER, J.S. AND MINICH, M.L.: "Synthesis of C(6)-carboxylate analogues of N-acetylmuramic acid", J. ORG. CHEM., vol. 55, no. 24, 1990, pages 6051 - 4, XP001117552 *
KAHNE D: "COMBINATORIAL APPROACHES TO CARBOHYDRATES", CURRENT OPINION IN CHEMICAL BIOLOGY, CURRENT BIOLOGY LTD, LONDON, GB, vol. 1, 1997, pages 130 - 135, XP000884351, ISSN: 1367-5931 *
KHIM. PRIR. SOEDIN., vol. 6, 1988, pages 850 - 5 *
KISS, J. AND BURKHARDT, F.: "Ungesättigte Zucker. Eine milde Sulfonat-beta-Eliminierung bei Aminohexopyranosiduronat-Derivaten", HELV. CHIM. ACTA, vol. 52, no. 8, 1969, pages 2622 - 36, XP001117785 *
PATENT ABSTRACTS OF JAPAN *
PAULSEN, H. AND LORENTZEN, J.P.: "Darstellung von beta-glycosidisch verknüpften Sacchariden der 2-Amino-2-desoxy-D-mannose", CARBOHYDR. RES., vol. 133, 1984, pages C1 - C4, XP001118179 *
See also references of WO9853813A1 *

Also Published As

Publication number Publication date
AU7700098A (en) 1998-12-30
WO1998053813A1 (fr) 1998-12-03
JP2002502393A (ja) 2002-01-22
EP0998280A1 (fr) 2000-05-10

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