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EP0972507A1 - Feuille de fermeture avec pistes conductrices - Google Patents

Feuille de fermeture avec pistes conductrices Download PDF

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Publication number
EP0972507A1
EP0972507A1 EP99810435A EP99810435A EP0972507A1 EP 0972507 A1 EP0972507 A1 EP 0972507A1 EP 99810435 A EP99810435 A EP 99810435A EP 99810435 A EP99810435 A EP 99810435A EP 0972507 A1 EP0972507 A1 EP 0972507A1
Authority
EP
European Patent Office
Prior art keywords
conductor tracks
ohms
computer
conductor
cover film
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99810435A
Other languages
German (de)
English (en)
Inventor
Christian Styger
Markus Lüthi
Thomas Linsi
Wolfgang Lohwasser
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
3A Composites International AG
Original Assignee
Alusuisse Lonza Services Ltd
Alusuisse Technology and Management Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alusuisse Lonza Services Ltd, Alusuisse Technology and Management Ltd filed Critical Alusuisse Lonza Services Ltd
Publication of EP0972507A1 publication Critical patent/EP0972507A1/fr
Withdrawn legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
    • A61J7/0409—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
    • A61J7/0481—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers working on a schedule basis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/03—Containers specially adapted for medical or pharmaceutical purposes for pills or tablets
    • A61J1/035—Blister-type containers

Definitions

  • Cover film with conductor tracks for connectable to a computer
  • the pharmaceutical packaging comprising a plurality of Contains depressions that are filled with filling material and at least one conductor track every depression lies.
  • This well-known drug container represents a drug packaging that the professional also known as a blister pack.
  • the conductor tracks are in the cover film of such pharmaceutical containers as impulse lines appropriate.
  • Pharmaceutical packaging of this type i.e. Blister packs in general continuously produced in large numbers on packaging machines. It is in the Rule a plastic monofilm or plastic composite film through depths with depressions or well.
  • the content to be packaged such as coated tablets or tablets, Capsules, ampoules and the like are filled into the wells and the cover film is then sealed.
  • the blister packs are usually produced continuously from ribbon-shaped foils and only after filling the content and covers, cut to size and, if necessary, in one Bottled packaging.
  • EP-B 0 129 785 or EP-A 0 796 605 it is a device for Storage and to remind a patient of the need to take medication, consisting of a pharmaceutical packaging and a signal transmitter, known.
  • the signal generator is switched on via an impulse line Start pulse supplied.
  • the impulse line is cast in a push-through second film and the dragees in the drug packaging are in one with troughs provided first film and the push-through second film or the Conductor tracks are applied to a label, which in turn covers the packaging.
  • the object of the present invention is to propose a cover film with conductor tracks, which does not have the disadvantages described and to describe conductor tracks which convey a reliably recognizable signal to the computer.
  • this is achieved in that the total electrical resistance at one or more intact conductor tracks, from 100 to 100,000 ⁇ (ohms) between the measuring points defined by the sampling points of the computer.
  • the minimum total electrical resistance is expediently 200 ⁇ (ohms), preferably 2000 ⁇ (ohms), particularly preferably 10,000 ⁇ (ohms) and in particular 20,000 ⁇ (ohms).
  • the maximum total electrical resistance is expediently 80,000 ⁇ (ohms), preferably 70,000 ⁇ (ohms), particularly preferably 60,000 ⁇ (ohms) and in particular 50,000 ⁇ (Ohm).
  • the total electrical resistance can be caused by the conductor track alone or by the Conductor and at least one additional resistance can be achieved.
  • the scanning points on the computer represent the interface between the cover film and the conductor tracks and the contacts of the computer that act on the conductor tracks.
  • the conductor tracks are applied to a carrier material.
  • the carrier material can Cover film for closing the bottom part or a label to fix on the Be lid material.
  • a carrier film for example, can be used as the carrier material for the label a plastic film of high brittleness, such as a polyolefin film, a polyethylene film or a polyvinyl chloride film can be used.
  • brittleness by adding fillers, e.g. Talk, mica, etc. can be achieved.
  • Other Plastic films can be films containing acrylonitrile styrene.
  • papers or semi-cardboard can also be used as carrier materials.
  • carrier materials are metal foils or metal foils that are on one or both sides further layers, such as layers of lacquer or plastic films and the like, are coated.
  • the substrates mentioned can be used Foils and papers are used. These protective materials can be used on the Base material covering the conductor tracks can be defined. They are advantageous Labels, for reasons of variety, from the same materials for each Carrier material and protective material built up.
  • the material for protecting the conductor tracks can also be sprayed on in the form of a protective lacquer, sprayed, rolled or painted protective layer or it can be vapor-deposited, vacuum-vapor-deposited or sputtered layers.
  • the conductor tracks can be made from an electrically conductive film or from wires or a electrically conductive paint or powder coating or a vapor-deposited or in Vacuum evaporated electrically conductive layer.
  • the electrically conductive paint can contain electrically conductive substances and paint carriers, solvents, etc.
  • the Electrically conductive lacquer can also be solvent-free.
  • the electrical conductivity in Varnishing can be achieved by inorganic compounds such as metals or semimetals, e.g. Metal powder or dust, especially platelet-shaped nickel, silver-coated platelet-shaped nickel, nickel, iron, copper, silver powder, etc. or by Carbon, for example in the form of carbon black, coke and preferably graphite or through Oxide mixtures can be achieved.
  • Preferred as conductor tracks in the context of the present invention are conductor tracks containing an SnO 2 / Sb 2 O 3 hydroxide mixture on a mica substrate.
  • the SnO 2 / Sb 2 O 3 hydroxide mixture advantageously has a layer thickness on the mica particles of 8 to 20, advantageously 16 to 20 nanometers.
  • the SnO 2 / Sb 2 O 3 hydroxide mixture on the mica particles is a conductive pigment.
  • the ratio Sn / Sb is expediently 95: 5 to 75:25, a ratio of 85:15 being preferred.
  • the grain size of the mica can be, for example, from 10 to 100 ⁇ m and the grain size of the mica is expediently less than 15 ⁇ m.
  • a lacquer can contain the electrically conductive pigment, for example the SnO 2 / Sb 2 O 3 hydroxide mixture on the mica substrate, and a binder.
  • Melamine resins, acrylic melamine resins, polyurethane paints, nitrocellulose paints, acrylic nitrocellulose paints, etc. are used as binders in such paints.
  • the proportion of binder in the lacquer can be, for example, from 10 to 60% by weight and advantageously from 10 to 25% by weight.
  • the proportion of electrically conductive pigment can be 40 to 90% by weight and advantageously 75 to 90% by weight in the lacquer.
  • a filler such as TiO 2 can be used , for example, in a grain size equal to or smaller than 15 ⁇ m and in a ratio of electrically conductive pigment to filler of 1: 1, or fillers in the form of porous spherical particles a grain size of greater than 30 ⁇ m and known under the brand name LiChrospher from Merck, in a ratio of 1: 1 of electrically conductive pigment to filler.
  • Varnishes for producing conductor tracks can be brushed onto the substrate by brush on, spray on, etc., if necessary with a template or by printing on Offset, gravure, letterpress or screen printing etc. take place.
  • Further methods for generating Conductor tracks on the carrier material are electrostatic processes, processes according to Decal principle, photochemical reproduction processes or photochemical printing processes, such as by applying a full-surface lacquer film, fixing the conductor pattern and remove the paint surfaces that are not required.
  • Other methods of generation of conductor tracks is the generation of layers by vapor deposition, for example in vacuum (chemical vapor deposition, physical vapor deposition, sputtering).
  • the structuring of vapor-deposited electrically conductive layers can, for example, by a Local application of a layer prior to the vapor deposition process, either prevents the adhesion of the electrically conductive layer or the condensation of the steam.
  • liable or anti-condensation layers are e.g. Silicone oils in Vacuum applied.
  • a vapor-deposited layer can also be masked after vapor deposition and then structured using etching processes. Structuring is also through local evaporation of the layer possible using laser or electron beams.
  • a Another form of structuring of the vapor-deposited electrically conductive layer lies in one Process according to which a solvent-soluble lacquer before the vapor deposition process applied to the carrier by, for example, a gravure, screen or high-pressure process becomes. After the coated support has been evaporated, the paint is removed by a solvent replaced again. Inevitably, the varnish also evaporates Layers replaced. The evaporated remains on the unpainted areas of the carrier surface Layer and thus the desired conductor pattern back.
  • the conductor tracks can be run in series or in parallel over the depressions and Correspondingly, a conductor track can be placed over all depressions or one conductor track can be created over one of several series of wells or each well can be covered by a single conductor track and each conductor track has its own Connection to the computer. These conductor tracks can receive their information via a connection to the computer.
  • the computer can a due to the information of an interrupted trace Time interval program specified by the computer or triggered by a circuit on the label start by showing the correct time to take the next tablet and show the taking times according to the program. It can also Withdrawal time can be registered by the computer and based on this the Calculator determine the next due time and via a signal generator specify.
  • the time of withdrawal can be specified by various control commands, like a display with time indication, by colored light-emitting diodes, acoustically by one Warning tone and the like. Or by a combination of the control commands.
  • the computer can determine whether the package is still unopened or due to being partially interrupted by medication Conductor tracks calculate the medication level and with the appropriate intake interval Continue.
  • the conductor tracks can be brought together in at least one place on the pharmaceutical packaging, i.e. bundled, and arranged so that the computer there on the drug packaging get in touch with the computer connections. This place can also be called the sampling point of the computer.
  • the conductor tracks can also be used with the Seal the pharmaceutical packaging flush on at least one side or can protrude at least one side of the pharmaceutical packaging and on this side the Conductors merged, i.e. bundled, and arranged so that the Computer there to be fixed on the pharmaceutical packaging and / or on the label can and the conductor tracks and the computer connections can come into contact.
  • Existing conductor tracks can also be used on cover material for closing or covering a bottom part can be used for the packaging of small parts.
  • Small parts of a technical nature can be accommodated in blister packs and the Blister packs can be covered by a cover material with conductor tracks.
  • the track in the label is interrupted and it can e.g. a security system against unauthorized removal can be activated or the impulse can be fed to a computer for inventory control or the like.
  • FIGS. 1 and 2 explain the present invention in more detail by way of example.
  • Figure 1 shows a Top view of a pharmaceutical packaging.
  • Figure 2 shows the top view of a further arrangement of conductor tracks on a cover film.
  • FIG. 1 shows the top view of a pharmaceutical packaging, such as a blister pack 1, with its depressions 2.
  • a computer 5 is by means of a slide-in connection or by means of a clamp, snap, snap or other contact connection with the blister pack 1 connected.
  • the clamp connection are activated and the conductor tracks 3 ending on the side edge 9 of the blister pack 1 are connected to mating contacts on the computer.
  • the resistance of everyone Conductor according to the present invention is measured between the measuring points that are defined by the sampling points of a computer. The sampling points are therefore included In the present example on the side edge 9.
  • the computer 5 contains a clock function and represents a memory for the ongoing changes in the measured total resistance.
  • the computer 5 has, for example, a time display 6 and - as a signal generator - e.g. a Display of the time of the next medication intake and / or a sound generator on.
  • the reminder process for the patient can be recognized by light-emitting diodes 7 made or visually enhanced.
  • the computer and therefore the signal generator is reusable and can be reset to zero, for example, by pressing 8 become.
  • the conductor tracks 3 are applied to the cover material 10. On the side edge 9 the connections to the computer 5 are available.
  • the computer 5 can each due to emitted pulses one, several or all conductor tracks at the same time recognize that the Drug withdrawal has occurred or is due or overdue.
  • the computer 5 is like this designed that the contacts along the side edge
  • FIG. 2 shows the top view of a blister pack 1 connectable computers not shown.
  • the blister pack 1 is closed with a cover film 10.
  • the depressions 2 are indicated in a circle.
  • Conductor 3 arranged.
  • the connections are on a side edge 9 of the cover material 10 11 available for the sampling points of the computer.
  • the conductor track 3 can for example be applied by a printing technique. Therefore, the conductor track 3 can the entire cover film 10 have the same thickness.
  • the conductor tracks 3 are bundled into common wide sections 13 and split into narrow conductor sections 14.
  • the narrow ones Conductor sections 14 cover the depressions 2 as the conductor track 3.
  • the resistance in the wide conductor sections 13 is measured by the resistance of a narrow conductor section 14 small.
  • the narrow conductor section 14 can be extended by a loop shape.
  • the narrow conductor sections 14 have a high resistance and when Breaking through a narrow conductor section 14 when removing a tablet a recess 2, by piercing the cover film 10, there is a high Change in resistance, respectively.

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Packages (AREA)
EP99810435A 1998-05-29 1999-05-19 Feuille de fermeture avec pistes conductrices Withdrawn EP0972507A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH118198 1998-05-29
CH118198 1998-05-29

Publications (1)

Publication Number Publication Date
EP0972507A1 true EP0972507A1 (fr) 2000-01-19

Family

ID=4204400

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99810435A Withdrawn EP0972507A1 (fr) 1998-05-29 1999-05-19 Feuille de fermeture avec pistes conductrices

Country Status (2)

Country Link
EP (1) EP0972507A1 (fr)
CA (1) CA2272017A1 (fr)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004028438A3 (fr) * 2002-09-24 2004-06-24 Intelligent Devices Inc Dispositif d'emballage analogique et systeme de controle de l'utilisation du contenu
DE10335284A1 (de) * 2003-07-28 2005-02-24 Infineon Technologies Ag Vorrichtung zur Aufbewahrung von festen und/oder flüssigen und/oder gasförmigen Gegenständen
WO2006002667A1 (fr) * 2004-06-30 2006-01-12 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Emballage-blister
EP2113236A1 (fr) 2008-04-28 2009-11-04 Alcan Technology & Management Ltd. Feuille de couverture et/ou de fermeture pour un emballage ainsi que procédé et système de détermination de l'état de l'ouverture d'un emballage
EP2113235A1 (fr) 2008-04-28 2009-11-04 Alcan Technology & Management AG Feuille de couverture et de fermeture pour un emballage et procédé de détermination de l'état de l'ouverture d'un emballage
EP2826456A1 (fr) * 2013-06-28 2015-01-21 Commissariat à l'Énergie Atomique et aux Énergies Alternatives Membrane et système de contrôle d'une ouverture de la membrane
DE102017214267A1 (de) * 2017-08-16 2019-02-21 Mahle International Gmbh Kühlvorrichtung und Verfahren zum Herstellen der Kühlvorrichtung
US11185468B2 (en) 2014-04-28 2021-11-30 The Regents Of The University Of California Unobtrusive wireless electronic systems for monitoring and facilitating patient compliance
US12494277B2 (en) 2020-11-20 2025-12-09 Michael K. Steinhauser Medication adherence system

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10479007B2 (en) 2017-03-17 2019-11-19 Rehrig Pacific Company Injection molded component and method of injection molding

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0129785A2 (fr) 1983-06-25 1985-01-02 Udo Simon Conteneur pour médicaments
US4616316A (en) * 1982-07-01 1986-10-07 The United States Of America As Represented By The Administrator Of Veterans Affairs Medication compliance monitoring device having conductive traces upon a frangible backing of a medication compartment
US5313439A (en) * 1992-07-17 1994-05-17 Dan Albeck Timer device for medications
EP0796605A1 (fr) 1996-03-21 1997-09-24 Alusuisse Technology & Management AG Feuille de fermeture avec pistes conductrices

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4616316A (en) * 1982-07-01 1986-10-07 The United States Of America As Represented By The Administrator Of Veterans Affairs Medication compliance monitoring device having conductive traces upon a frangible backing of a medication compartment
EP0129785A2 (fr) 1983-06-25 1985-01-02 Udo Simon Conteneur pour médicaments
US5313439A (en) * 1992-07-17 1994-05-17 Dan Albeck Timer device for medications
EP0796605A1 (fr) 1996-03-21 1997-09-24 Alusuisse Technology & Management AG Feuille de fermeture avec pistes conductrices

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004028438A3 (fr) * 2002-09-24 2004-06-24 Intelligent Devices Inc Dispositif d'emballage analogique et systeme de controle de l'utilisation du contenu
DE10335284A1 (de) * 2003-07-28 2005-02-24 Infineon Technologies Ag Vorrichtung zur Aufbewahrung von festen und/oder flüssigen und/oder gasförmigen Gegenständen
US7466230B2 (en) 2003-07-28 2008-12-16 Hueck Folien Gesellschaft M.B.H. Device for the storage of solid and/or liquid and/or gaseous objects
DE10335284B4 (de) * 2003-07-28 2009-09-10 Hueck Folien Gesellschaft M.B.H. Vorrichtung zur Aufbewahrung von festen und/oder flüssigen und/oder gasförmigen Gegenständen
WO2006002667A1 (fr) * 2004-06-30 2006-01-12 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Emballage-blister
EP2113236A1 (fr) 2008-04-28 2009-11-04 Alcan Technology & Management Ltd. Feuille de couverture et/ou de fermeture pour un emballage ainsi que procédé et système de détermination de l'état de l'ouverture d'un emballage
EP2113235A1 (fr) 2008-04-28 2009-11-04 Alcan Technology & Management AG Feuille de couverture et de fermeture pour un emballage et procédé de détermination de l'état de l'ouverture d'un emballage
EP2826456A1 (fr) * 2013-06-28 2015-01-21 Commissariat à l'Énergie Atomique et aux Énergies Alternatives Membrane et système de contrôle d'une ouverture de la membrane
US11185468B2 (en) 2014-04-28 2021-11-30 The Regents Of The University Of California Unobtrusive wireless electronic systems for monitoring and facilitating patient compliance
DE102017214267A1 (de) * 2017-08-16 2019-02-21 Mahle International Gmbh Kühlvorrichtung und Verfahren zum Herstellen der Kühlvorrichtung
DE102017214267B4 (de) 2017-08-16 2025-02-20 Mahle International Gmbh Kühlvorrichtung und Verfahren zum Herstellen der Kühlvorrichtung
US12494277B2 (en) 2020-11-20 2025-12-09 Michael K. Steinhauser Medication adherence system

Also Published As

Publication number Publication date
CA2272017A1 (fr) 1999-11-29

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