EP0971592A1

EP0971592A1 - Synergetic fungicide composition

Info

Publication number: EP0971592A1
Application number: EP98917280A
Authority: EP
Inventors: Joelle Donnadieu; Patrice Duvert; Richard Mercer
Original assignee: Rhone Poulenc Agro SA; Rhone Poulenc Agrochimie SA
Current assignee: Bayer CropScience SA
Priority date: 1997-04-04
Filing date: 1998-04-01
Publication date: 2000-01-19
Also published as: ZA982863B; FR2761577A1; IL132157A0; HRP980178A2; KR100523200B1; CA2285649A1; WO1998044801A1; BR9815465A; AU7053798A; CO5040023A1; CA2285649C; KR20010005930A; FR2761577B1; US6358938B1

Abstract

Disclosed is a synergetic fungicide composition comprising propamocarbe and a derivative of phosphorous acid. The invention further proposes a process for the preventive or curative combat of phytopathogenic mushrooms which employs this composition.

Description

Synergistic fungicidal composition.

The subject of the present invention is a synergistic fungicidal composition comprising propamocarb and a phosphorous acid derivative and a process using said composition and intended to protect, for curative or preventive purposes, cultures against fungal attacks.

It is always desirable to improve the spectrum of activity and the effectiveness of such fungicidal compounds, or to reinforce them by combining them with other molecules in order to obtain a more effective product (association with a systemic fungicide, these fungicides being rather molecules of the "contact" type) or else to prevent the appearance of fungal strains resistant to these new fungicides.

It is also very desirable to have fungicidal products benefiting from an improved persistence of action, so as to space over time the number of phytosanitary treatments necessary for good pest control.

In all cases, it is particularly advantageous to be able to reduce the quantity of chemicals spread in the environment, while ensuring effective protection of crops against fungal attacks.

It has now been found that one (or more) of the foregoing objectives can be achieved with the fungicidal composition according to the present invention.

The present invention therefore relates primarily to a synergistic fungicidal composition comprising as compound A propamocarb, also called propyl 3- (dimethlylamino) propylcarbamate, and at least one fungicidal compound B chosen from the group comprising phosphorous acid derivatives such as metallic phosphites such as fosetyl-Al, and phosphorous acid itself and its alkali or alkaline earth salts. The fungicidal composition according to the invention advantageously comprises the components A and B in a weight ratio A / B of between 1/12 and 12/1, preferably between 1/3 and 3/1, and even more advantageously in a ratio equal to 1. It is understood that said fungicidal composition can contain a single compound B or more of such a compound, for example 1, 2 or 3 compounds B depending on the use for which it is intended.

Among the more especially preferred meanings of compound B defined above, more preferred is fosetyl Al. Preferably, the composition is not applied to turf. Unexpectedly, the composition according to the invention then significantly improves the action of the active ingredients taken separately for a number of mushrooms which are particularly harmful to crops, such as in particular the vine or solanaceae. This improvement is reflected in particular by a reduction in the doses of each of the constituents, which is particularly advantageous for the user and the environment. The fungicide product thus exhibits synergistic properties attested by the application of the method of Tammes, "Isoboles, a graphie representation of synergism in pesticides" Netherlands Journal of Plant Pathology, 70 (1964), p. 73-80.

Preferably, when component B is fosetyl-Al, the A / B ratio is between 1/3 and 3/1, and even more advantageously this ratio is equal to 1 for all of the cultures envisaged.

The structures corresponding to the common names of the active ingredients A and B are indicated in at least one of the following 2 works:

- "The pesticide manual" edited by Clive TOMLIN and published by the British Crop Protection Council, 10th edition (pages 843 and 530); - the 1994 Phytosanitary Index, published by the Association of

Agricultural Technical Coordination, 30th edition.

The fungicidal composition according to the invention comprises, as active material, a compound A and at least one compound B in admixture with solid or liquid carriers, acceptable in agriculture and or surfactants also acceptable in agriculture. In particular, the usual inert supports and the usual surfactants can be used. These compositions cover not only the compositions ready to be applied to the culture to be treated by means of a suitable device, such as a spraying device, but also the concentrated commercial compositions which must be diluted before application on culture. The term active ingredient denotes the combination of at least one compound A with at least one compound B.

These compositions can also contain all kinds of other ingredients such as, for example, protective colloids, adhesives, thickeners, thixotropic agents, penetration agents, stabilizers, sequestrants, etc. More generally compounds A and B can be combined with any solid or liquid additive corresponding to the usual techniques of formulation.

In general, the compositions according to the invention usually contain from 0.05 to 95% (by weight) of active material, one or more solid or liquid supports and, optionally, one or more surfactants.

By the term "support", in the present description, is meant an organic or mineral, natural or synthetic material, with which the active material is combined to facilitate its application to the aerial parts of the plant. This support is therefore generally inert and it must be acceptable in agriculture, in particular on the treated plant. The support can be solid (clays, natural or synthetic silicates, silica, resins, waxes, solid fertilizers, etc.) or liquid (water, alcohols, in particular butanol etc.). The surfactant can be an emulsifying, dispersing or wetting agent of ionic or nonionic type or a mixture of such surfactants. Mention may be made, for example, of salts of polyacrylic acids, salts of lignosulfonic acids, salts of phenolsulfonic or naphthalene sulfonic acids, polycondensates of ethylene oxide on fatty alcohols or on fatty acids or on fatty amines , substituted phenols

(in particular alkylphenols or arylphenols), salts of sulfosuccinic acid esters, taurine derivatives (in particular alkyltaurates), phosphoric esters of polyoxyethylated alcohols or phenols, esters of fatty acids and polyols , sulphate, sulphonate and phosphate derivatives of the above compounds. The presence of at least one surfactant is generally essential when the active material and / or the inert support are not soluble in water and the vector agent for the application is water.

Thus, the compositions for agricultural use according to the invention can contain the active material within very wide limits, ranging from 0.05% to 95% (by weight). Their content of surfactant is advantageously between 5% and 40% by weight. Unless otherwise indicated the percentages given in this description, including the claims, are by weight.

These compositions according to the invention are themselves in fairly diverse forms, solid or liquid. As forms of solid compositions, mention may be made of powders for dusting (with an active material content of up to 100%) and granules, in particular those obtained by extrusion, by compacting, by impregnation of a granulated support, by granulation. from a powder (the active ingredient content in these granules being between 0.5 and 80% for the latter cases), the effervescent tablets or tablets.

The fungicidal composition according to the invention can also be used in the form of powders for dusting; one can also use a composition comprising 50 g of active material and 950 g of talc; one can also use a composition comprising 20 g of active material, 10 g of finely divided silica and 970 g of talc; these constituents are mixed and ground and the mixture is applied by dusting.

As forms of liquid compositions or intended to constitute liquid compositions during application, mention may be made of solutions, in particular water-soluble concentrates, emulsions, concentrated suspensions, aerosols, wettable powders (or powder to spray), pasta, gels.

The concentrated suspensions, applicable in spraying, are prepared so as to obtain a stable fluid product which does not deposit and they usually contain from 10 to 75% of active material, from 0.5 to 15% of surfactants, from 0, 1 to 10% of thixotropic agents, from 0 to 10% of suitable additives, such as defoamers, corrosion inhibitors, stabilizers, penetrating agents and adhesives and, as support, water or an organic liquid in which the active ingredient is sparingly or not very soluble: certain organic solids or mineral salts can be dissolved in the support to help prevent sedimentation or as antifreeze for water.

As an example, here is a concentrated suspension composition: Example SC 1:

- active ingredient 500 g

- polyethoxylated tristyrylphenol phosphate 50 g

- polyethoxylated alkylphenol 50 g

- sodium polycarboxylate 20 g

- ethylene glycol 50 g

- organopolysiloxane oil (antifoam) 1 g

- polysaccharide 1.5 g - water 316.5 g

Wettable powders (or spray powder) are usually prepared so that they contain 20 to 95% of active ingredient, and they usually contain, in addition to the solid support, 0 to 30% of a wetting agent, 3 20% of a dispersing agent, and, when necessary, 0.1 to 10% of one or more stabilizers and / or other additives, such as penetrating agents, adhesives, or anti-caking agents, dyes, etc.

To obtain the sprayable powders or wettable powders, the active ingredients are intimately mixed in the appropriate mixers with the additional substances and ground with mills or other suitable grinders. This gives sprayable powders whose wettability and suspension are advantageous; they can be suspended with water at any desired concentration and these suspensions can be used very advantageously in particular for application to the leaves of plants.

Instead of wettable powders, pasta can be made. The conditions and methods of making and using these pastes are similar to those of wettable powders or spraying powders.

As an example, here are various compositions of wettable powders (or spraying powders):

Example PM 1

- active ingredient 50%

- ethoxylated fatty alcohol (wetting agent) 2.5%

- ethoxylated phenylethylphenol (dispersing agent) 5%

- chalk (inert support) 42.5% Example PM 2:

- active ingredient 10%

- branched type oxo synthetic alcohol, C13 ethoxylated with 8 to 10 ethylene oxide (wetting agent) 0.75%

- neutral calcium lignosulfonate (dispersing agent) 12%

- calcium carbonate (inert filler) q.s.p. 100%

Example PM 3:

This wettable powder contains the same ingredients as in the previous example, in the proportions below:

- active ingredient 75%

- wetting agent 1.50% - dispersing agent 8%

- calcium carbonate (inert filler) q.s.p. 100%

Example PM 4:

- active ingredient 90% - ethoxylated fatty alcohol (wetting agent) 4%

- ethoxylated phenylethylphenol (dispersing agent) 6%

Example PM 5:

- active material 50% - mixture of anionic and nonionic surfactants (wetting agent) 2.5%

- sodium lignosulfonate (dispersing agent) 5%

- kaolin clay (inert support) 42.5%

The aqueous dispersions and emulsions, for example the compositions obtained by diluting with water a wettable powder or an emulsifiable concentrate according to the invention, are included in the general scope of the present invention. The emulsions can be of the water-in-oil or oil-in-water type and they can have a thick consistency like that of a "mayonnaise". The fungicidal compositions according to the invention can be formulated in the form of water-dispersible granules also included within the scope of the invention.

These dispersible granules, of apparent density generally comprised between approximately 0.3 and 0.6 have a particle size generally comprised between approximately 150 and 2000 and preferably between 300 and 1500 microns.

The active material content of these granules is generally between approximately 1% and 90%, and preferably between 25% and 90%.

The rest of the granule is essentially composed of a solid filler and optionally surfactant additives giving the granule properties of dispersibility in water. These granules can be essentially of two distinct types depending on whether the selected filler is soluble or not in water. When the filler is water-soluble, it can be mineral or, preferably, organic. Excellent results have been obtained with urea. In the case of an insoluble filler, it is preferably mineral, such as for example kaolin or bentonite. It is then advantageously accompanied by surfactants (at a rate of 2 to 20% by weight of the granule) of which more than half is, for example, constituted by at least one dispersing agent, essentially anionic, such as a polynaphthalene alkaline or alkaline earth sulfonate or an alkaline or alkaline earth lignosulfonate, the remainder being nonionic or anionic wetting agents such as an alkali or alkaline earth alkyl naphthalene sulfonate.

Furthermore, although this is not essential, other adjuvants can be added such as anti-foaming agents.

The granule according to the invention can be prepared by mixing the necessary ingredients and then granulation according to several techniques known per se (bezel, fluid bed, atomizer, extrusion, etc.). It generally ends with a crushing followed by sieving to the particle size chosen within the limits mentioned above. It is also possible to use granules obtained as above and then impregnated with a composition containing the active material. Preferably, it is obtained by extrusion, operating as indicated in the examples below.

Example GD 1: Dispersible granules

In a mixer, 90% by weight of active material and 10% urea pearls are mixed. The mixture is then ground in a pin mill. A powder is obtained which is moistened with approximately 8% by weight of water. The wet powder is extruded in a perforated roller extruder. A granule is obtained which is dried, then crushed and sieved, so as to keep respectively only the granules of a size between 150 and 2000 microns.

Example GD2: Dispersible granules

In a mixer, the following constituents are mixed:

- active ingredient 75%

- wetting agent (sodium alkylnaphthalene sulfonate) 2% - dispersing agent (sodium polynaphthalene sulfonate) 8%

- inert filler insoluble in water (kaolin) 15%

This mixture is granulated in a fluid bed, in the presence of water, then dried, crushed and sieved so as to obtain granules of size between 0.15 and 0.80 mm.

These granules can be used alone, in solution or dispersion in water so as to obtain the desired dose. They can also be used to prepare combinations with other active materials, in particular fungicides, the latter being in the form of wettable powders, or aqueous granules or suspensions.

As regards the compositions suitable for storage and transport, they more advantageously contain from 0.5 to 95% (by weight) of active material.

Another subject of the invention is a method of combating, for curative or preventive purposes, against phytopathogenic fungi of cultures, characterized in that an effective and non-phytotoxic amount of is applied to the aerial parts of the plants or to the soil. a combination of compound A and at least one compound B, for example in a fungicidal composition according to the invention.

The phytopathogenic fungi of cultures which can be combated by this process are in particular those:

- from the oomycetes group:

- of the genus Phytophthora such as Phytophthora phaseoli, Phytophthora citrophthora, Phytophthora capsici, Phytophthora cactorum, Phytophthora palmivora, Phytophthora cinnamoni, Phytophthora megasperma, Phytophthora parasitica, Phytophthora fragariae, Phytophthora cryptogea, Phytophthora porri, Phytophthora nicotianae, Phytophthora infestons;

- from the Peronosporaceae family, in particular Plasmopara viticola (downy mildew), Plasmopara halstedei (sunflower downy mildew), Pseudoperonospora sp (especially downy mildew of cucurbits)

(Pseudoperonospora cubensis) and hops (Pseudoperonospora humili)), Bremia lactucae (lettuce downy mildew), Peronospora tabacinae (tobacco late blight), Peronospora destructor (cruciferous late blight), Peronospora parasitica (cabbage late blight), Peronospora farinosa endives and downy beet).

The crops envisaged in the context of the present invention are preferably vegetable crops (beans, onions, cucurbits, cabbage, potatoes, tomatoes, peppers, spinach, peas, lettuce, endives), fruit crops (strawberries, raspberries) , tree crops (apple, pear, ginseng, lemon, coconut, cocoa, rubber, banana), vines, sunflowers, beets, tobacco and ornamental crops.

The fungicidal composition which is the subject of the invention is applied by means of various treatment methods such as:

- spraying the aerial parts of the cultures to be treated with a liquid comprising said composition,

- dusting, incorporating granules or powders into the soil, watering, injecting into trees or painting. Spraying a liquid on the aerial parts of the crops to be treated is the preferred treatment method.

By "effective and non-phytotoxic amount" means an amount of composition according to the invention sufficient to allow the control or destruction of the fungi present or likely to appear on the cultures, and not causing for said cultures any significant symptom of phytotoxicity.

Such an amount is likely to vary within wide limits depending on the fungus to be combated, the type of crop, the climatic conditions, and the compounds included in the fungicidal composition according to the invention. This quantity can be determined by systematic field tests, within the reach of those skilled in the art. The doses of use during the implementation of the process according to the invention will generally then be on vines, vegetable crops, arboriculture, citrus fruits, etc.: by foliar treatment:

500 to 6000 g / ha of compound B, e.g. fosetyl-Al, + 500 to 6000 g / ha of compound A and more precisely 1000 to 3000 g / ha + 1000 to 3000 g / ha, or a total dose of composition according to the invention of between 1000 and 12000 g / ha, preferably between 2000 and 6000 g / ha. Preferably, a total dose of composition according to the invention is used equal to 3000 g / ha, or 1500 g / ha of compound A

+ 1500 g / ha of compound B.

by ground treatment (watering):

25 to 300 kg / ha of compound B, e.g. fosetyl-Al, + 25 to 300 kg / ha of compound A and more specifically 50 to 150 kg / ha + 50 to 150 kg / ha, or a total dose of composition according to the invention of between 50 and 600 kg / ha, preferably between 100 and 300 kg / ha. Preferably, a total dose of composition according to the invention is used equal to 200 kg / ha, ie 100 kg / ha of compound A + 100 kg / ha of compound B.

The following examples are given purely by way of illustration of the invention, which they in no way limit.

Example 1: Vine trial.

The fungicides tested are:

Aliette WP: formulation P containing 80% fosetyl- Ai / kg, Prévicur N: formulation SL containing 722g of propamocarb / 1.

The fungicidal compositions tested are as follows:

Aliette at doses of 62, 125, 250, 500, 1000, 2000 and 4000 ppm of active ingredient (a.i.). Prévicur N at doses of 62, 125, 250, 500, 1000, 2000 and 4000 ppm of a.m.

Aliette + Prévicur at doses of 125 + 62, 250 + 125, 500 + 250, 1000 + 500,

2000 + 1000 and 4000 + 2000 ppm ai (2/1 ratio) Aliette + Prévicur at doses of 125 + 125, 250 + 250, 500 + 500, 1000 + 1000,

2000 + 2000 and 4000 + 4000 ppm of m.a. (ratio 1/1)

Vine plants (var. Chardonnay) 8 weeks old are treated with the fungicidal compositions at the doses mentioned above (3 repetitions / dose). One day after treatment, the plants are contaminated with an aqueous suspension containing 100,000 spores of Plasmopara viticola / ml of inoculum. The plants are then placed in a climate cell at 20 ° C, 100% RH (relative humidity) for 9 days.

A notation is then carried out. This consists of estimating the proportion of sick plant for each test factor and, by comparison with an untreated-contaminated control, defining the percentage of effectiveness according to the following formula:

% practical efficiency = 100 x (% control contamination -% contamination

Test) /% contamination Control

The theoretical efficiency according to Colby's formula is calculated according to the following formula:

% theoretical efficiency A + B =% eff. practical A +% eff. practice B - (% eff. practice A x% eff. practice B / 100)

Practical effectiveness (observed):

Prévicur (ppm)

0 62 125 250 500 1000 2000 4000

0 0 0 12 5 12 21 39

62 0

Aliette 125 0 0 0

(ppm) 250 9 12 4

500 18 21 29

1000 54 54 70

2000 68 79 100

4000 91 96 100

Theoretical efficiency (according to Colby):

Prévicur (ppm)

0 62 125 250 500 1000 2000 4000

0 0 0 12 5 12 21 39

62 0

Aliette 125 0 0 0

(ppm) 250 9 9 20

500 18 28 22

1000 54 56 60

2000 68 72 75

4000 91 93 95 Synergy values:

Prévicur (ppm)

0 62 125 250 500 1000 2000 4000

0 0 0 12 5 12 21 39

62 0

Aliette 125 0 0 0

(ppm) 250 9 +3 -16

500 18 -7 +7

1000 54 -2 +10

2000 68 +7 +25

4000 91 +3 +5

A good relationship: synergistic is noted.

Example 2: Cabbage test

The fungicides tested are:

Aliette WP: WP formulation containing 80% fosetyl- Ai / kg, Prévicur N: SL formulation containing 722g of propamocarb / 1.

The fungicidal compositions tested are as follows:

Aliette at doses of 125, 250, 500, 1000, 2000, 4000 and 8000 ppm of active ingredient (a.i.).

Prévicur N at doses of 125, 250, 500, 1000 and 2000 ppm of a.m.

Aliette + Prévicur at doses of 500 + 125, 1000 + 250, 2000 + 500, 4000 + 1000 and 8000 + 2000 ppm of m.a. (ratio 4/1) Aliette + Prévicur at doses of 250 + 125, 500 + 250, 1000 + 500, 2000 + 1000 and 4000 + 2000 ppm of a.m. (2/1 ratio)

Aliette + Prévicur at doses of 125 + 125, 250 + 250, 500 + 500, 1000 + 1000 and

2000 + 2000 ppm of m.a. (ratio 1/1)

Cabbage plants (var. Brunswick Cabus) 10 days old are treated with the fungicidal compositions at the doses mentioned above (3 repetitions / dose). One day after treatment, the plants are contaminated with an aqueous suspension containing 50,000 spores of Peronospora by inoculum asiticalirλ. The plants are then placed in a climate cell at 15 ° C, 100% RH (relative humidity) for 6 days.

A notation is then carried out. This consists of estimating the proportion of sick plant for each test factor and, by comparison with an untreated-contaminated control, defining the percentage of effectiveness according to the following formula:% practical efficiency = 100 x (% contamination Control -% contamination Test) /% contamination Control The theoretical efficiency according to Colby's formula is calculated according to the following formula:

Practical effectiveness (observed):

Prévicur (ppm)

0 125 250 500 1000 2000

0 0 7 17 73 94

Aliette 125 0 0

(ppm) 250 0 0 60

500 0 3 20 87

1000 0 53 73 97

2000 20 87 95 100

4000 47 98 99

8000 83 100

Theoretical efficiency (according to Colby):

Prévicur (ppm)

0 125 250 500 1000 2000

0 0 7 17 73 94

Aliette 125 0 0

(ppm) 250 0 0 7

500 0 0 7 17

1000 0 7 17 73

2000 20 34 78 95

4000 47 89 97

8000 83 99

Synergy values

Prévicur (ppm)

0 125 250 500 1000 2000

0 0 7 17 73 94

Aliette 125 0 0

(ppm) 250 0 0 +53

500 0 +3 +13 +70

1000 0 +46 +56 +24

2000 20 +53 +17 +5

4000 47 +12 +2

8000 83 +1

A good synergistic relationship is noted. Example 3: Test on potato.

The fungicides tested are:

Aliette WP: WP formulation containing 80% fosetyl-Al / kg,

Prévicur N: SL formulation containing 722g of propamocarb / 1.

The fungicidal compositions tested are as follows:

Aliette at doses of 500, 1000, 2000, 4000 and 8000 ppm of active ingredient (a.i.).

Prévicur N at doses of 62, 125, 250, 500, 1000, 2000 and 4000 ppm of a.m.

Aliette + Prévicur at doses of 500 + 125, 1000 + 250, 2000 + 500, 4000 + 1000 and 8000 + 2000 ppm of m.a. (ratio 4/1) Aliette + Prévicur at doses of 500 + 250, 1000 + 500, 2000 + 1000,

4000 + 2000 and 8000 + 4000 ppm of m.a. (2/1 ratio)

Aliette + Prévicur at doses of 500 + 500, 1000 + 1000, 2000 + 2000 and

4000 + 4000 ppm of m.a. (ratio 1/1)

Potato plants (var. Bintge) aged 3 weeks are treated with the fungicidal compositions at the doses mentioned above (2 repetitions / dose). One day after treatment, the plants are contaminated with an aqueous suspension containing 30,000 spores of Phytophtora infestons (strain F4.95) / ml of inoculum. The plants are then placed in a climate cell at 10 ° C, 100% RH (relative humidity) for 5 days. They are then transferred to 15 ° C for 4 additional days and are finally placed in a greenhouse at 20 ° C, 100% RH for 2 more days.

% practical efficiency = 100 x (% control contamination -% test contamination) /% control contamination

Results.

Practical effectiveness (observed):

Prévicur (ppm) 0 62 125 250 500 1000 2000 4000

0 0 0 0 0 20 20 45

500 0 10 0 0

Aliette 1000 0 10 0 10

(ppm) 2000 0 15 5 30

4000 0 15 25 60

8000 15 25 40

Theoretical efficiency (according to Colby):

Prévicur (ppm)

0 62 125 250 500 1000 2000 4000

0 0 0 0 0 20 20 45

500 0 0 0 0

Aliette 1000 0 0 0 20

(ppm) 2000 0 0 20 20

4000 0 20 20 45

8000 15 32 53

Synergy values

Prévicur (ppm)

0 62 125 250 500 1000 2000 4000

0 0 0 0 0 20 20 45

500 0 +10 0 0

Aliette 1000 0 +10 0 -10

(ppm) 2000 0 +15 -15 +10

4000 0 -5 +5 +15

8000 15 +7 -13

A synergistic relationship is noted.

Claims

1. Synergistic fungicidal composition comprising as compound A propamocarb and at least one fungicidal compound B chosen from the group comprising phosphorous acid derivatives such as metal phosphites such as fosetyl-Al, and phosphorous acid itself and its alkali or alkaline earth salts; said composition comprising components A and B in an A / B weight ratio of between 1/12 and 12/1, preferably between 1/3 and 3/1.

2. Fungicidal composition according to claim 1 characterized in that the compound B is fosetyl Al.

3. fungicidal composition according to one of claims 1 to 2, characterized in that the composition is preferably not applied to turf.

4. fungicidal composition according to any one of claims 2 or 3, characterized in that the A / B ratio is between 1/3 and 3/1, and even more advantageously this ratio is equal to 1 for the all the crops envisaged.

6. fungicidal composition according to any one of claims 1 to 5, characterized in that it comprises compounds A and B in admixture with solid or liquid carriers acceptable in agriculture and / or surfactants also acceptable in agriculture .

7. fungicidal composition according to any one of claims 1 to 6, characterized in that it comprises from 0.05 to 95% (by weight) of active material.

8. Method for controlling phytopathogenic fungi in a medium, characterized in that a compound A and at least one compound B are applied to said medium, these compounds being as defined in claim 1, and the combination of these compounds being in a total effective and non-phytotoxic amount

9. A method of combating, for curative or preventive purposes, against phytopathogenic fungi of cultures, characterized in that an effective and non-phytotoxic amount of a fungicidal composition is applied to the aerial parts of the plants or to the soil. 'any of claims 1 to 7.

10. Control method according to claim 9 characterized in that a liquid is sprayed comprising the fungicidal composition according to any one of claims 1 to 7 on the aerial parts of the crops to be treated

11. Method for combating phytopathogenic fungi of crops according to claim 10, characterized in that a total dose of composition of between 1000 and 12,000 g / ha, preferably between 2000 and 6000 g / ha, is applied by foliar treatment .

12. Control method according to claim 11 characterized in that one applies a total dose of composition equal to 3000 g / ha.

13. Process for combating phytopathogenic fungi in crops according to claim 9, characterized in that a total dose of composition of between 50 and 600 kg / ha, preferably between 100 and 300 kg / ha, is applied to the soil.

14. Control method according to claim 13 characterized in that one applies a total dose of composition equal to 200 kg / ha.

15. A product comprising at least one compound A and at least one compound B for the control of phytopathogenic fungi in a medium by simultaneous, sequential or separate application.