EP0830367A4 - Ligands de cytokines a acide nucleique et d'une affinite elevee - Google Patents

Ligands de cytokines a acide nucleique et d'une affinite elevee

Info

Publication number: EP0830367A4
Authority: EP; European Patent Office
Prior art keywords: cytokines; nucleic acid; acid ligands; affinity nucleic; affinity
Prior art date: 1995-06-07
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP96919214A

Other languages

German (de)

English (en)

Other versions

EP0830367A1 (fr

Inventor

Diane Tasset

Nikos Pagratis

Sumedha Jayasena

Larry Gold

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Gilead Sciences Inc

Original Assignee

Nexstar Pharmaceuticals Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-06-07

Filing date

1996-06-04

Publication date

2003-03-05

1995-06-07 Priority claimed from US08/477,527 external-priority patent/US5972599A/en

1995-06-07 Priority claimed from US08/481,710 external-priority patent/US6028186A/en

1996-06-04 Application filed by Nexstar Pharmaceuticals Inc filed Critical Nexstar Pharmaceuticals Inc

1996-06-04 Priority to EP08010881A priority Critical patent/EP2011503A3/fr

1998-03-25 Publication of EP0830367A1 publication Critical patent/EP0830367A1/fr

2003-03-05 Publication of EP0830367A4 publication Critical patent/EP0830367A4/fr

Status Withdrawn legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/16—Aptamers
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/32—Chemical structure of the sugar
- C12N2310/322—2'-R Modification

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Biomedical Technology (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Molecular Biology (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
Zoology (AREA)
Bioinformatics & Cheminformatics (AREA)
Wood Science & Technology (AREA)
Microbiology (AREA)
Plant Pathology (AREA)
Biophysics (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Physics & Mathematics (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

EP96919214A 1995-06-07 1996-06-04 Ligands de cytokines a acide nucleique et d'une affinite elevee Withdrawn EP0830367A4 (fr)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
EP08010881A EP2011503A3 (fr)	1995-06-07	1996-06-04	Ligands d'acide nucléique à haute affinité de cytokines

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US481710		1995-06-07
US08/477,527 US5972599A (en)	1990-06-11	1995-06-07	High affinity nucleic acid ligands of cytokines
US08/481,710 US6028186A (en)	1991-06-10	1995-06-07	High affinity nucleic acid ligands of cytokines
US477527		1995-06-07
PCT/US1996/009537 WO1996040717A1 (fr)	1995-06-07	1996-06-04	Ligands de cytokines a acide nucleique et d'une affinite elevee

Related Child Applications (1)

Application Number	Title	Priority Date	Filing Date
EP08010881A Division EP2011503A3 (fr)	1995-06-07	1996-06-04	Ligands d'acide nucléique à haute affinité de cytokines

Publications (2)

Publication Number	Publication Date
EP0830367A1 EP0830367A1 (fr)	1998-03-25
EP0830367A4 true EP0830367A4 (fr)	2003-03-05

Family

ID=27045583

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP96919214A Withdrawn EP0830367A4 (fr)	1995-06-07	1996-06-04	Ligands de cytokines a acide nucleique et d'une affinite elevee

Country Status (4)

Country	Link
EP (1)	EP0830367A4 (fr)
JP (1)	JPH11507529A (fr)
CA (1)	CA2223003A1 (fr)
WO (1)	WO1996040717A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1999033479A1 (fr) *	1997-12-31	1999-07-08	University Of Iowa Research Foundation	Utilisation d'agents biologiques parasitaires permettant de prevenir et de lutter contre les maladies auto-immunes
US6171795B1 (en) *	1999-07-29	2001-01-09	Nexstar Pharmaceuticals, Inc.	Nucleic acid ligands to CD40ligand
EP1489171B1 (fr)	2002-03-19	2012-10-31	Fujitsu Limited	Molecule fonctionnelle et son procede de production
US9303262B2 (en) *	2002-09-17	2016-04-05	Archemix Llc	Methods for identifying aptamer regulators
RU2006135119A (ru) *	2004-03-05	2008-04-10	Аркемикс Корп. (Us)	Аптамеры к семейству цитокинов il-12 человека и их применение в качестве лекарственных средств для аутоиммунных заболеваний
JP2019535249A (ja) *	2016-10-24	2019-12-12	バイオイズカンパニーリミテッド	ＴＮＦ−α結合アプタマー及びその治療的用途
EP3781688A4 (fr) *	2018-04-20	2021-06-23	Academia Sinica	Aptamères ciblant le facteur tnf et leurs utilisations pour le traitement ou le diagnostic de maladies inflammatoires associées au tnf

Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1995007364A1 (fr) *	1993-09-08	1995-03-16	Nexstar Pharmaceuticals, Inc.	Acides nucleiques servant de ligands et procedes de production ameliores

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5270163A (en) *	1990-06-11	1993-12-14	University Research Corporation	Methods for identifying nucleic acid ligands
IE920562A1 (en) *	1991-02-21	1992-08-26	Gilead Sciences	Aptamer specific for biomolecules and method of making

1996
- 1996-06-04 JP JP9501840A patent/JPH11507529A/ja active Pending
- 1996-06-04 CA CA002223003A patent/CA2223003A1/fr not_active Abandoned
- 1996-06-04 EP EP96919214A patent/EP0830367A4/fr not_active Withdrawn
- 1996-06-04 WO PCT/US1996/009537 patent/WO1996040717A1/fr not_active Ceased

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1995007364A1 (fr) *	1993-09-08	1995-03-16	Nexstar Pharmaceuticals, Inc.	Acides nucleiques servant de ligands et procedes de production ameliores

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BUDINGER T F ET AL: "New approaches to targeting arthritis with radiopharmaceuticals.", THE JOURNAL OF RHEUMATOLOGY. SUPPLEMENT. CANADA FEB 1995, vol. 43, February 1995 (1995-02-01), pages 62 - 67, XP001098388, ISSN: 0380-0903 *
JELLINEK D ET AL: "INHIBITION OF RECEPTOR BINDING BY HIGH-AFFINITY RNA LIGANDS TO VASCULAR ENDOTHELIAL GROWTH FACTOR", BIOCHEMISTRY, AMERICAN CHEMICAL SOCIETY. EASTON, PA, US, vol. 34, no. 33, 30 August 1994 (1994-08-30), pages 10450 - 10456, XP001084739, ISSN: 0006-2960 *
See also references of WO9640717A1 *

Also Published As

Publication number	Publication date
JPH11507529A (ja)	1999-07-06
WO1996040717A1 (fr)	1996-12-19
CA2223003A1 (fr)	1996-12-19
EP0830367A1 (fr)	1998-03-25

Publication	Publication Date	Title
AU4068393A (en)	1993-12-13	Method of sequencing dna
GB9210273D0 (en)	1992-07-01	Dna
GB9212164D0 (en)	1992-07-22	Preparation of nucleic acids
GR3031775T3 (en)	2000-02-29	Interferon solution
PL315687A1 (en)	1996-11-25	Comparative analysis of gene transcript
AU6042396A (en)	1996-12-24	Amplification of nucleic acid sequences
IL122528A0 (en)	1998-06-15	Catalytic dna
AP9300538A0 (en)	1993-07-31	New dna sequences
IL121090A0 (en)	1997-11-20	Aryl and heteroaryl purine compounds
AU8260491A (en)	1992-02-27	Dna sequencing
EP0517515A3 (en)	1993-06-16	Method of purifying dna
IL118306A0 (en)	1996-09-12	Ataxia-telangiectasia gene
GB9502468D0 (en)	1995-03-29	DNA Sequence
EP0830367A4 (fr)	2003-03-05	Ligands de cytokines a acide nucleique et d'une affinite elevee
GB9526218D0 (en)	1996-02-21	DNA Sequences
AU3004695A (en)	1996-02-09	Nucleic acid filters
GB9410170D0 (en)	1994-07-06	Nucleic acid
GB9207598D0 (en)	1992-05-20	Method of sequencing double stranded dna
IL118493A0 (en)	1996-09-12	Delta P62 its variants nucleic acid sequences and their uses
EP0801526A4 (fr)	1999-12-01	Systeme de transduction de genes
AU5539096A (en)	1996-11-07	Nucleic acid sequencing
AU6486796A (en)	1997-02-10	Intracellular action of nucleic acid ligands
IL112141A0 (en)	1995-03-15	Nucleic acid ligands
GB9224386D0 (en)	1993-01-13	Nucleic acid sequence
GB9226165D0 (en)	1993-02-10	Nucleic acid sequence

Legal Events

Date	Code	Title	Description
1998-02-06	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
1998-03-25	17P	Request for examination filed	Effective date: 19971202
1998-03-25	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
2002-12-04	RIC1	Information provided on ipc code assigned before grant	Free format text: 7C 07H 21/02 A, 7C 07H 21/04 B, 7C 12P 19/34 B, 7C 12Q 1/68 B, 7C 12N 15/10 B, 7C 07H 21/00 B
2003-03-05	A4	Supplementary search report drawn up and despatched	Effective date: 20030121
2003-05-28	17Q	First examination report despatched	Effective date: 20030414
2003-11-19	RAP1	Party data changed (applicant data changed or rights of an application transferred)	Owner name: GILEAD SCIENCES, INC.
2007-01-03	17Q	First examination report despatched	Effective date: 20030414
2008-02-14	GRAP	Despatch of communication of intention to grant a patent	Free format text: ORIGINAL CODE: EPIDOSNIGR1
2008-11-21	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2008-12-24	18D	Application deemed to be withdrawn	Effective date: 20080703