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EP0868712A1 - Appareil portatif de simulation d'examens aux ultrasons - Google Patents

Appareil portatif de simulation d'examens aux ultrasons

Info

Publication number
EP0868712A1
EP0868712A1 EP96944074A EP96944074A EP0868712A1 EP 0868712 A1 EP0868712 A1 EP 0868712A1 EP 96944074 A EP96944074 A EP 96944074A EP 96944074 A EP96944074 A EP 96944074A EP 0868712 A1 EP0868712 A1 EP 0868712A1
Authority
EP
European Patent Office
Prior art keywords
flow model
model according
portable flow
examination
portable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP96944074A
Other languages
German (de)
English (en)
Inventor
Jörg PETRICK
Michael STÄHLE
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Publication of EP0868712A1 publication Critical patent/EP0868712A1/fr
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G09—EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
    • G09B—EDUCATIONAL OR DEMONSTRATION APPLIANCES; APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND, DEAF OR MUTE; MODELS; PLANETARIA; GLOBES; MAPS; DIAGRAMS
    • G09B23/00—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes
    • G09B23/28—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes for medicine
    • G09B23/286—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes for medicine for scanning or photography techniques, e.g. X-rays, ultrasonics

Definitions

  • the invention relates to the subject matter characterized in the claims, that is to say a portable flow model for the simulation of ultrasound examinations, in particular for the simulation of contrast-enhanced ultrasound examinations.
  • Sonography is a valuable aid in examinations of the vascular system.
  • an echogenic substance is added to the system, the acoustic impedance of which is significantly higher than blood fluid. Since the impedance difference between gases and liquids is particularly large, suspensions containing fine gas bubbles are known to be very effective ultrasound contrast agents. The use of such contrast agents not only offers advantages in the B-picture, but also when working under unfavorable PA conditions in the color Doppler or spectral Doppler.
  • FIG. 1 shows the structure of the flow model in FIG. 1. The functions of the individual components are explained below.
  • Figure 2 shows the examination chamber (6) in a spatial representation and in side view.
  • the flow circuit contains an injection point (1) through which, if desired, the contrast medium can be injected into the circuit.
  • Suitable materials are e.g. Rubber septa, as they are widely used for storage bottles (vials) for liquid pharmaceuticals.
  • the contrast medium or the medium in circulation passes to a pump (2) which represents the heart.
  • Suitable pumps are centrifugal or diaphragm pumps etc. with controllable pumping capacity. Because such Pumps have a constant delivery, but in the present case a pulsative flow (as corresponds to the in vivo blood flow) is desired, it is necessary to influence the flow by a suitable device. This is done according to the invention by dividing the pump flow via a branch onto two hoses (branches) connected in parallel. A constant flow is regulated via one of the two branches via a throttle (3), which essentially corresponds to the diastolic flow velocity in the desired vessel to be examined.
  • the other branch contains a clocked valve (4) which alternately switches to passage or blocking, the switching clock (the switching frequency) corresponding to the natural pulse frequency.
  • the two branches then unite again, a pulsative flow behavior being achieved by the superimposition of both rivers.
  • valve control can be done with a simple clock. Elaborate electronics such as If comparable flow ratios were to be achieved by varying the pump speed, this can be avoided.
  • This structure (via the type of timing and the degree of throttling) also allows the flow conditions to be adapted to the in vivo conditions as they exist in different vessels.
  • FIG. 3 shows the flow conditions in the femoral artery under in vivo conditions (top) and simulated in the flow model (bottom).
  • FIG. 4 shows a comparison of the flow conditions in the carotid artery (in vivo / above; in vitro / below). In both cases, a good agreement between the curve profiles in vivo and in vitro is observed.
  • the core of the flow model is the examination chamber (6), which represents the body region to be examined and can be made of different materials. Transparent materials, such as plexiglass, are advantageously used to give the user an insight into the examination room. Since the chamber is filled with a liquid medium, it must be made in a watertight design. Water or sound-reducing fluids are suitable media.
  • the lines represent the vessels to be examined and can be changed artificially, for example by making constrictions that simulate a stenosis, for example. In this case, one tube contains the "pathological" change, whereas the other tube serves as a reference.
  • the tubes are made of thin-walled material that has an acoustic impedance that corresponds to the physiological conditions. Various plastics are suitable, such as polypropylene or silicone.
  • the chamber also contains an elastic examination window (8), which serves as a kind of skin replacement and against which the transducer of the respective ultrasound device can be placed.
  • the examination window is placed over the tubes (5) and made of a material that is permeable to ultrasound (such as silicone).
  • This structure allows any ultrasound device to be “connected” to the circuit, which makes it possible for the user to take advantage of the effect of a circuit Get to know contrast media on his own ultrasound machine.
  • a medium that has a damping for ultrasound that corresponds to that of body tissue can be introduced between the examination window and the pipelines.
  • Damping medium can e.g. Be polyurethane rubber, which is worked in a wedge shape.
  • This damping wedge (7) simulates different tissue layer thicknesses depending on the insertion depth. The wedge thus acts in depth (see also Figure 2).
  • This arrangement thus also allows the simulation of deep-lying vessels without having to change the geometry of the arrangement. This is an advantage because it enables a direct comparison of different examinations under otherwise identical conditions (such as angle of incidence and reflection).
  • Throttle (9) serves as an adjustable flow resistance, via which the flow velocity can also be regulated. With the help of the adjustable throttle, the flow profiles can also be influenced in order to achieve an even better adaptation to the physiological conditions.
  • This restrictor essentially serves to limit the upper limit of the pressure prevailing in the circuit to a value which corresponds to the systolic pressure.
  • the flow circuit is filled with a medium that serves as a blood substitute. Suitable are liquid media which have viscosities similar to blood, such as water-glycerol mixtures, which may optionally contain additives such as silver salts for disinfection in order to prevent algae formation in the circulation. Particulate components such as cellulose fibers or latex particles can also be added to the fluid in order to simulate flow properties which correspond to those of blood.
  • the liquid used in addition to the viscosity, also differs only slightly from blood liquid in its solution properties compared to the contrast medium used and in its acoustic properties.
  • the circuit can be filled or emptied via a filler neck (not shown in FIG. 1), which can be located at any point in the circuit. This ensures easy cleaning, which is required, for example, after a large number of contrast medium injections.
  • the water can also be drained off before the device is transported so as not to unnecessarily increase the weight of the model.
  • the chamber (6) is also provided with a separate filler neck, which can also be emptied before transport.
  • the model is carried in a portable case, e.g. in a briefcase.
  • the power supply of the system can be switched over via a mains connection or battery operation.
  • the model according to the invention enables the user to carry out a sonography examination in a realistic manner. Its compact and lightweight design enables it to be used widely in "workshops” and “in-house” training. This makes it possible for the later user of contrast media to demonstrate the advantages of the same directly using his own ultrasound scanner. The simple design allows almost maintenance-free use.
  • FIG. 1 + 2 An exemplary embodiment of the invention is illustrated by the schematic representation of the circulatory model (FIGS. 1 + 2). It means:

Landscapes

  • Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Computational Mathematics (AREA)
  • Mathematical Optimization (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Algebra (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mathematical Analysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Mathematical Physics (AREA)
  • Pure & Applied Mathematics (AREA)
  • Business, Economics & Management (AREA)
  • Educational Administration (AREA)
  • Educational Technology (AREA)
  • Theoretical Computer Science (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Instructional Devices (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

Ce modèle portatif d'écoulement sert à simuler des examens aux ultrasons et comprend un point d'injection (1), une pompe (2), un clapet d'étranglement (3), une soupape (4), une chambre d'examen (6) pourvue d'une fenêtre d'examen (8) et un autre clapet d'étranglement (9) qui sert de résistance. Ces composants individuels sont mutuellement reliés par un système de tuyauteries.
EP96944074A 1995-12-21 1996-12-19 Appareil portatif de simulation d'examens aux ultrasons Ceased EP0868712A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19549240A DE19549240A1 (de) 1995-12-21 1995-12-21 Tragbares Gerät zur Simulation von Ultraschalluntersuchungen
DE19549240 1995-12-21
PCT/EP1996/005855 WO1997023855A1 (fr) 1995-12-21 1996-12-19 Appareil portatif de simulation d'examens aux ultrasons

Publications (1)

Publication Number Publication Date
EP0868712A1 true EP0868712A1 (fr) 1998-10-07

Family

ID=7781707

Family Applications (1)

Application Number Title Priority Date Filing Date
EP96944074A Ceased EP0868712A1 (fr) 1995-12-21 1996-12-19 Appareil portatif de simulation d'examens aux ultrasons

Country Status (6)

Country Link
US (1) US6039573A (fr)
EP (1) EP0868712A1 (fr)
JP (1) JP2000503127A (fr)
AU (1) AU1379397A (fr)
DE (1) DE19549240A1 (fr)
WO (1) WO1997023855A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6264917B1 (en) 1996-10-28 2001-07-24 Nycomed Imaging As Targeted ultrasound contrast agents
US6331289B1 (en) 1996-10-28 2001-12-18 Nycomed Imaging As Targeted diagnostic/therapeutic agents having more than one different vectors
US6261537B1 (en) 1996-10-28 2001-07-17 Nycomed Imaging As Diagnostic/therapeutic agents having microbubbles coupled to one or more vectors
EP1171780A1 (fr) * 1999-04-20 2002-01-16 Synthes Ag Chur Dispositif permettant d'obtenir par voie percutanee des coordonnees tridimensionnelles a la surface d'un organe d'humain ou d'animal
US6629469B2 (en) * 2000-06-05 2003-10-07 Data Spectrum Corporation Cardiac phantom
WO2006086115A1 (fr) * 2005-02-10 2006-08-17 Wilkins Jason D Mannequin d’apprentissage ultrasonique
JP2009122130A (ja) * 2006-03-03 2009-06-04 Univ Waseda 冠動脈バイパス手術用の訓練評価システム
US8926333B2 (en) * 2013-03-15 2015-01-06 Simnext, Llc Device, system, and method for simulating blood flow
JP6343762B2 (ja) * 2013-11-28 2018-06-20 国立大学法人 筑波大学 医療用超音波診断訓練システム及び医療用超音波診断訓練方法
RU2611905C2 (ru) * 2015-04-29 2017-03-01 Государственное бюджетное образовательное учреждение высшего профессионального образования "Смоленский государственный медицинский университет" Министерства здравоохранения Российской Федерации Устройство для обучения диагностике патологии внутренних органов методом эхоконтрастирования

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4894013A (en) * 1988-10-13 1990-01-16 The United States Of America As Represented By The Department Of Health And Human Services Anthropomorphic cardiac ultrasound phantom
US5052934A (en) * 1990-04-20 1991-10-01 The United States Of America As Represented By The Department Of Health And Human Services Phantom for evaluation of prosthetic valves and cardiac ultrasound procedures
DE4035452A1 (de) * 1990-11-08 1992-06-04 Walter Rebsch Pulsflusskurvenmodulator
GB9104097D0 (en) * 1991-02-27 1991-04-17 Univ Hospital London Dev Corp Computer controlled positive displacement pump for physiological flow stimulation

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO9723855A1 *

Also Published As

Publication number Publication date
US6039573A (en) 2000-03-21
DE19549240A1 (de) 1997-07-10
AU1379397A (en) 1997-07-17
JP2000503127A (ja) 2000-03-14
WO1997023855A1 (fr) 1997-07-03

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