EP0722330A4 - Methode d'analyse des cellules-souches humaines - Google Patents

Methode d'analyse des cellules-souches humaines

Info

Publication number: EP0722330A4
Authority: EP; European Patent Office
Prior art keywords: analysis; methods; stem cells; human stem; human
Prior art date: 1993-10-07
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP94931328A

Other languages

German (de)

English (en)

Other versions

EP0722330A1 (fr

Inventor

Mark Phillip Backer

Judy Carol Young

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Systemix Inc

Original Assignee

Systemix Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-10-07

Filing date

1994-10-07

Publication date

1997-09-10

1994-10-07 Application filed by Systemix Inc filed Critical Systemix Inc

1996-07-24 Publication of EP0722330A1 publication Critical patent/EP0722330A1/fr

1997-09-10 Publication of EP0722330A4 publication Critical patent/EP0722330A4/fr

Status Withdrawn legal-status Critical Current

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5094—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/125—Stem cell factor [SCF], c-kit ligand [KL]
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/2303—Interleukin-3 (IL-3)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/2306—Interleukin-6 (IL-6)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/235—Leukemia inhibitory factor [LIF]
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
- C12N2502/1394—Bone marrow stromal cells; whole marrow

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Chemical & Material Sciences (AREA)
Hematology (AREA)
Immunology (AREA)
Cell Biology (AREA)
Biotechnology (AREA)
Molecular Biology (AREA)
Bioinformatics & Cheminformatics (AREA)
Genetics & Genomics (AREA)
Microbiology (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Biochemistry (AREA)
Urology & Nephrology (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
General Engineering & Computer Science (AREA)
Tropical Medicine & Parasitology (AREA)
Ecology (AREA)
Developmental Biology & Embryology (AREA)
Food Science & Technology (AREA)
Medicinal Chemistry (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Investigating Or Analysing Biological Materials (AREA)

EP94931328A 1993-10-07 1994-10-07 Methode d'analyse des cellules-souches humaines Withdrawn EP0722330A4 (fr)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US13280993A	1993-10-07	1993-10-07
US132809		1993-10-07
PCT/US1994/011456 WO1995009640A1 (fr)	1993-10-07	1994-10-07	Methode d'analyse des cellules-souches humaines

Publications (2)

Publication Number	Publication Date
EP0722330A1 EP0722330A1 (fr)	1996-07-24
EP0722330A4 true EP0722330A4 (fr)	1997-09-10

Family

ID=22455702

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP94931328A Withdrawn EP0722330A4 (fr)	1993-10-07	1994-10-07	Methode d'analyse des cellules-souches humaines

Country Status (4)

Country	Link
EP (1)	EP0722330A4 (fr)
AU (1)	AU8014694A (fr)
CA (1)	CA2173726A1 (fr)
WO (1)	WO1995009640A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5670347A (en)	1994-05-11	1997-09-23	Amba Biosciences Llc	Peptide-mediated gene transfer
US5811297A (en) *	1996-03-07	1998-09-22	Amba Biosciences, Llc	Immortalized hematopoietic cell lines, cell system thereof with stromal cells, in vitro, ex vivo and in vivo uses, & in vitro generation of dendritic cells and macrophages
DE69733694T2 (de) *	1996-07-10	2006-07-06	Muramatsu, Takashi, Nagoya	Verwendung von proteinen aus der mk familie als hämatopoietischer faktor
WO2000011476A1 (fr) *	1998-08-25	2000-03-02	The Immune Response Corporation	Procedes d'evaluation de la fonction immunitaire
GR1003638B (el) *	2000-07-13	2001-08-02	Μπουζιανασαγεωργιουαδημητριοσα	Μεθοδοσακυτταροκαλλιεργειασαγιαατηαμελετηατωνααρχεγονωνααιμοποιητικωνακυτταρωνατουαανθρωπουα
US20060166305A1 (en) *	2005-01-27	2006-07-27	Genetix Limited	Animal cell confluence detection method and apparatus
EP2746769A1 (fr) *	2012-12-21	2014-06-25	Stembios Technologies, Inc.	Procédé pour évaluer l'effet d'action sur un sujet basé sur des dynamiques cellulaires de tiges

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5199942A (en) *	1991-06-07	1993-04-06	Immunex Corporation	Method for improving autologous transplantation

1994
- 1994-10-07 EP EP94931328A patent/EP0722330A4/fr not_active Withdrawn
- 1994-10-07 WO PCT/US1994/011456 patent/WO1995009640A1/fr not_active Ceased
- 1994-10-07 AU AU80146/94A patent/AU8014694A/en not_active Abandoned
- 1994-10-07 CA CA002173726A patent/CA2173726A1/fr not_active Abandoned

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
See also references of WO9509640A1 *
SROUR E.F. ET AL.: "Long-Term Generation and Expansion of Human Primitive Hematopoietic Progenitor Cells in Vitro", BLOOD, vol. 81, no. 3, 1 February 1993 (1993-02-01), pages 661 - 669, XP002035018 *
WOLF N S ET AL: "IN VIVO AND IN VITRO CHARACTERIZATION OF LONG-TERM REPOPULATING PRIMITIVE HEMATOPOIETIC CELLS ISOLATED BY SEQUENTIAL HOECHST 33342-RHODAMINE 123 FACS SELECTION", EXPERIMENTAL HEMATOLOGY, vol. 21, no. 5, May 1993 (1993-05-01), pages 614 - 622, XP000604780 *
XIAO M. ET AL.: "Extensive Proliferation Capacity of Single Isolated CD34+++ Human Cord Blood Cells in Suspension Culture", BLOOD CELLS, vol. 20, no. 2-3, 1994, pages 455 - 466, XP002035019 *

Also Published As

Publication number	Publication date
CA2173726A1 (fr)	1995-04-13
WO1995009640A1 (fr)	1995-04-13
EP0722330A1 (fr)	1996-07-24
AU8014694A (en)	1995-05-01

Publication	Publication Date	Title
US4714680B1 (en)	1995-06-27	Human stem cells
US5035994B1 (en)	1995-02-14	Human stem cells and monoclonal antibodies
US5130144B1 (en)	1995-08-15	Human stem cells and monoclonal antibodies
AU6223296A (en)	1996-12-30	Methods for obtaining compositions enriched for hematopoieti c stem cells and antibodies for use therein
IL109008A0 (en)	1994-06-24	Immunoassy for determination of cells
EP0732931A4 (fr)	1998-08-05	Procedes pour l'incorporation et la mise en culture de tissus
PL327827A1 (en)	1999-01-04	Method of retarding the skin photoageing process
DE69637669D1 (de)	2008-10-16	Myogene differenzierung menschlicher mesenchymaler stammzellen
EP0652703A4 (fr)	1996-05-29	Methodes d'immunoselection positive de cellules souches.
GB9310604D0 (en)	1993-07-07	Analysis of heart waveforms
EP0662512A3 (fr)	1997-01-15	Cellules souches hématopoiétiques humaines.
EP0722330A4 (fr)	1997-09-10	Methode d'analyse des cellules-souches humaines
ZA968896B (en)	1997-04-24	Method of mobilizing hematopoietic stem cells
GB9215710D0 (en)	1992-09-09	Analysis of cells
GB8809419D0 (en)	1988-05-25	Stem cell inhibitors
IL109795A0 (en)	1994-08-26	Method for the quantitative determination of human thyroid peroxidase and kit for carrying out the method
AU4594696A (en)	1997-06-05	Human stem cell antigen 2
AU2281395A (en)	1995-11-10	Method of hair analysis
PL317372A1 (en)	1997-04-01	Method of measuring electrochemical activity
IL107212A0 (en)	1994-01-25	Method and device for the cultivation of cells
AUPN115095A0 (en)	1995-03-09	Analysis of and compositions and methods for the treatment of disease
EP0692969A4 (fr)	1997-08-20	Procede de traitement d'une maladie par la suppression des lymphocytes t
EP0787795A4 (fr)	1998-11-25	Proteine variante de l'adn topoisomerase i humaine
PL297500A1 (en)	1994-07-25	Method of obtaining 4-phenyl-benzophenone
IL113347A (en)	1999-11-30	Brain endothelial cell protein and methods for its use

Legal Events

Date	Code	Title	Description
1996-06-07	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
1996-07-24	17P	Request for examination filed	Effective date: 19960429
1996-07-24	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
1997-09-10	A4	Supplementary search report drawn up and despatched	Effective date: 19970723
1997-09-10	AK	Designated contracting states	Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
1999-01-29	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
1999-03-17	18D	Application deemed to be withdrawn	Effective date: 19980504