EP0675723A4 - Therapie utilisant des bisphosphonates et des strogenes en vue de traiter et de prevenir la resorption osseuse. - Google Patents

Therapie utilisant des bisphosphonates et des strogenes en vue de traiter et de prevenir la resorption osseuse.

Info

Publication number: EP0675723A4
Authority: EP; European Patent Office
Prior art keywords: biphosphonate; treating; bone loss; preventing bone; estrogen therapy
Prior art date: 1992-12-23
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Ceased

Application number

EP94905419A

Other languages

German (de)

English (en)

Other versions

EP0675723A1 (fr

Inventor

Donna T Whiteford

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Merck and Co Inc

Original Assignee

Merck and Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-12-23

Filing date

1993-12-17

Publication date

1998-08-05

1993-12-17 Application filed by Merck and Co Inc filed Critical Merck and Co Inc

1995-10-11 Publication of EP0675723A1 publication Critical patent/EP0675723A1/fr

1998-08-05 Publication of EP0675723A4 publication Critical patent/EP0675723A4/fr

Status Ceased legal-status Critical Current

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

EP94905419A 1992-12-23 1993-12-17 Therapie utilisant des bisphosphonates et des strogenes en vue de traiter et de prevenir la resorption osseuse. Ceased EP0675723A4 (fr)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US99641892A	1992-12-23	1992-12-23
US996418		1992-12-23
PCT/US1993/012302 WO1994014455A1 (fr)	1992-12-23	1993-12-17	Therapie utilisant des bisphosphonates et des ×strogenes en vue de traiter et de prevenir la resorption osseuse

Publications (2)

Publication Number	Publication Date
EP0675723A1 EP0675723A1 (fr)	1995-10-11
EP0675723A4 true EP0675723A4 (fr)	1998-08-05

Family

ID=25542895

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP94905419A Ceased EP0675723A4 (fr)	1992-12-23	1993-12-17	Therapie utilisant des bisphosphonates et des strogenes en vue de traiter et de prevenir la resorption osseuse.

Country Status (5)

Country	Link
EP (1)	EP0675723A4 (fr)
JP (1)	JPH08505142A (fr)
AU (1)	AU5953894A (fr)
CA (1)	CA2151240A1 (fr)
WO (1)	WO1994014455A1 (fr)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK0625355T5 (da) *	1993-05-15	2003-12-01	Roche Diagnostics Gmbh	Tablet med forbedret biotilgængelighed indeholdende dichlormethylendiphosphonsyre som virksomt stof
US5646134A (en) *	1994-04-21	1997-07-08	Merck & Co., Inc.	Alendronate therapy to prevent loosening of, or pain associated with, orthopedic implant devices
TW398975B (en) *	1994-07-22	2000-07-21	Lilly Co Eli	Pharmaceutical composition for inhibiting bone loss
US5780455A (en) *	1994-08-24	1998-07-14	Merck & Co., Inc.	Intravenous alendronate formulations
JPH10506638A (ja) *	1995-05-12	1998-06-30	メルクエンドカンパニーインコーポレーテッド	アレンドロネート又はその塩の投与による歯喪失の予防
US5545635A (en) *	1995-05-23	1996-08-13	Eli Lilly And Company	Inhibiting bone loss with equilenin
US5616571A (en) *	1995-06-06	1997-04-01	Merck & Co., Inc.	Bisphosphonates prevent bone loss associated with immunosuppressive therapy
IL120270A0 (en) *	1996-02-28	1997-06-10	Pfizer	Combination therapy to treat osteoporosis
IL120265A0 (en) *	1996-02-28	1997-06-10	Pfizer	Combination therapy to treat osteoporosis - polyphosphonates or progestins and estrogen agonists
US5853759A (en) *	1996-05-17	1998-12-29	Merck & Co.. Inc.	Effervescent alendronate formulation
EP1378234A1 (fr) *	1996-05-17	2004-01-07	MERCK & CO. INC.	Formulation de bisphosphonate effervescente
ATE256456T1 (de) *	1996-05-17	2004-01-15	Merck & Co Inc	Biphosphonat-formulierung mit brausewirkung
US6376477B2 (en)	1996-11-25	2002-04-23	Merck & Co., Inc.	Combination of an agent that binds to the androgen receptor and a bisphosphonic acid in the prevention and/or treatment of diseases involving calcium or phosphate metabolism
WO1998023274A1 (fr) *	1996-11-25	1998-06-04	Merck & Co., Inc.	Agents androgene et bisphosphonique coadministres pour traiter des maladies
DE19719680A1 (de) *	1997-05-09	1998-11-19	Boehringer Mannheim Gmbh	Verwendung von Diphosphonsäuren zur präventiven Behandlung von Spätfolgen bei Harnblasenerweiterung oder Harnblasenersatz
EP0998934A4 (fr) *	1997-12-25	2005-09-14	Toray Industries	Remedes contre les maladies intramedullaires
TR200101546T2 (tr) *	1998-12-04	2001-11-21	Roche Diagnostics Gmbh	İç-protezlerde kemik entegrasyonunu iyileştirmek üzere ibandronat kullanılması.
CA2370769A1 (fr) *	1999-04-22	2000-11-02	Hydromed Sciences A Division Of Gp Strategies Corporation	Administration regulee de bisphosphonates
AUPQ232599A0 (en) *	1999-08-19	1999-09-09	Royal Alexandra Hospital For Children, The	Drug for treating fractures
FR2803521B1 (fr)	2000-01-12	2002-10-25	Ceva Sante Animale	Utilisation de l'acide tiludronique et de ses derives chez la volaille pour la preparation d'un medicament destine a prevenir et a traiter l'osteoporose
MXPA03007029A (es) *	2001-02-06	2004-10-15	Royal Alexandra Hosp Children	Un farmaco para el tratamiento de osteonecrosis y para el manejo de pacientes en riesgo de desarrollar osteonecrosis.
US20040157798A1 (en) *	2001-04-03	2004-08-12	Little David Graham	Drug for use in bone grafting
AUPR553701A0 (en) *	2001-06-07	2001-07-12	Royal Alexandra Hospital For Children, The	A device for the delivery of a drug to a fractured bone
TWI315982B (en)	2001-07-19	2009-10-21	Novartis Ag	Combinations comprising epothilones and pharmaceutical uses thereof
WO2003057136A2 (fr)	2001-12-24	2003-07-17	Teva Pharmaceutical Industries Ltd.	Forme posologique avec pastille noyau de principe actif enrobee dans un corps annulaire comprime de poudre ou de substance granulaire, et procede et outils pour la production de cette forme posologique
US7488496B2 (en)	2002-03-06	2009-02-10	Christer Rosen	Effervescent compositions comprising bisphosphonates and methods related thereto
ES2561463T3 (es) *	2003-08-21	2016-02-26	Addbio Ab	Dispositivo de implante recubierto con bisfosfonato y método para el mismo
ES2379485T3 (es) *	2005-10-27	2012-04-26	Thommen Medical Ag	Implante dental y procedimiento para su fabricación
US8882740B2 (en)	2009-12-23	2014-11-11	Stryker Trauma Gmbh	Method of delivering a biphosphonate and/or strontium ranelate below the surface of a bone

Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1992005187A1 (fr) *	1990-09-18	1992-04-02	Boehringer Mannheim Gmbh	NOUVEAUX DERIVES DE 17-β-OESTRADIOL, LEUR PROCEDE DE PRODUCTION ET MEDICAMENTS CONTENANT CES COMPOSES
EP0496520A1 (fr) *	1991-01-22	1992-07-29	Merck & Co. Inc.	Agents actifs sur les os
WO1992014474A1 (fr) *	1991-02-26	1992-09-03	Norwich Eaton Pharmaceuticals, Inc.	Procede de traitement de l'osteoporose

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3623397A1 (de) *	1986-07-11	1988-01-14	Boehringer Mannheim Gmbh	Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel

1993
- 1993-12-17 CA CA002151240A patent/CA2151240A1/fr not_active Abandoned
- 1993-12-17 EP EP94905419A patent/EP0675723A4/fr not_active Ceased
- 1993-12-17 WO PCT/US1993/012302 patent/WO1994014455A1/fr not_active Ceased
- 1993-12-17 JP JP6515312A patent/JPH08505142A/ja active Pending
- 1993-12-17 AU AU59538/94A patent/AU5953894A/en not_active Abandoned

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1992005187A1 (fr) *	1990-09-18	1992-04-02	Boehringer Mannheim Gmbh	NOUVEAUX DERIVES DE 17-β-OESTRADIOL, LEUR PROCEDE DE PRODUCTION ET MEDICAMENTS CONTENANT CES COMPOSES
EP0496520A1 (fr) *	1991-01-22	1992-07-29	Merck & Co. Inc.	Agents actifs sur les os
WO1992014474A1 (fr) *	1991-02-26	1992-09-03	Norwich Eaton Pharmaceuticals, Inc.	Procede de traitement de l'osteoporose

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CIMINERA N. ET AL: "Studio Comparativo degli effeti di estrogeni e difosfonati sulla perdita ossea postmenopausale", ANN. OSTET. GINECOL. MED. PERINAT., vol. 113, no. 5, 1992, pages 232 - 237, XP002064831 *
See also references of WO9414455A1 *

Also Published As

Publication number	Publication date
JPH08505142A (ja)	1996-06-04
AU5953894A (en)	1994-07-19
CA2151240A1 (fr)	1994-07-07
EP0675723A1 (fr)	1995-10-11
WO1994014455A1 (fr)	1994-07-07

Publication	Publication Date	Title
EP0675723A4 (fr)	1998-08-05	Therapie utilisant des bisphosphonates et des strogenes en vue de traiter et de prevenir la resorption osseuse.
DE69739758D1 (de)	2010-03-25	Vakzine zur behandlung von lymphomen und leukämie
EP1079741A4 (fr)	2004-12-08	Attache pour tissu implantable et systeme permettant de traiter les affections de reflux gastro-oesophagien
DE69312624D1 (de)	1997-09-04	Vorrichtung zur unterscheidung von tachykardien und fibrillationen und zur entsprechenden behandlung
ATA11989A (de)	1990-12-15	Mittel zur vorbeugung gegen und behandlung von parodontopathien
DE69525473D1 (de)	2002-03-21	Vorrichtung zur behandlung von blutgefässen
DE69730604D1 (de)	2004-10-14	Oxadisäuren und verwandte verbindungen zur behandlung von hautstörungen
DE59410094D1 (de)	2002-05-08	Vorrichtung zur behandlung von biologischem gewebe und körperkonkrementen
DE69018457D1 (de)	1995-05-11	Gegenstände zur behandlung von periodontitis und knochendefekten.
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EP0709090A3 (fr)	1996-08-28	Compositions pour le traitement de tumeurs résistantes
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DE69318693D1 (de)	1998-06-25	Magnetischer Konditionierer zur Behandlung von Flüssigkeiten
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DE69817862D1 (de)	2003-10-09	Naringin und naringenin als mittel zur vorbeugung oder behandlung von leber-erkrankungen
DE69806801D1 (de)	2002-08-29	Galenische präparation zur prävention und behandlung von hepatokarzinomen
DE69729817D1 (de)	2004-08-19	Behandlung von Aldehyd-fixierten Geweben
DE69421196D1 (de)	1999-11-18	Vorrichtung zur behandlung von überbiss
DE69527140D1 (de)	2002-07-25	Wirkstoff zur prävention oder behandlung von osteoporose
DE69506019D1 (de)	1998-12-24	Vorrichtung zur Behandlung von Schmerz
DE69729004D1 (de)	2004-06-09	Photodynamische therapie zur behandlung von osteosrthritis
DE69727240D1 (de)	2004-02-19	Kombinationen enthaltend vx478, zidovudin und 3tc zur behandlung von hiv
DE59501606D1 (de)	1998-04-16	Vorrichtung zur behandlung von leiterplatten
DE69825319D1 (de)	2004-09-02	Präparat zur vorbeugung und behandlung von entzündungen
DE69721756D1 (de)	2003-06-12	Paroxetine zur behandlung von depression

Legal Events

Date	Code	Title	Description
1995-08-25	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
1995-10-11	17P	Request for examination filed	Effective date: 19950724
1995-10-11	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE
1998-08-05	A4	Supplementary search report drawn up and despatched	Effective date: 19980619
1998-08-05	AK	Designated contracting states	Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE
1998-11-25	17Q	First examination report despatched	Effective date: 19981008
2004-02-06	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION HAS BEEN REFUSED
2004-03-24	18R	Application refused	Effective date: 20031106
2006-07-28	REG	Reference to a national code	Ref country code: HK Ref legal event code: WD Ref document number: 1009249 Country of ref document: HK