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EP0584212A4 - Vaccins comprenant un polysaccharide encapsule dans un liposome. - Google Patents

Vaccins comprenant un polysaccharide encapsule dans un liposome.

Info

Publication number
EP0584212A4
EP0584212A4 EP19920911814 EP92911814A EP0584212A4 EP 0584212 A4 EP0584212 A4 EP 0584212A4 EP 19920911814 EP19920911814 EP 19920911814 EP 92911814 A EP92911814 A EP 92911814A EP 0584212 A4 EP0584212 A4 EP 0584212A4
Authority
EP
European Patent Office
Prior art keywords
polysaccharid
liposomal
vaccine
polysaccharid vaccine
liposomal polysaccharid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19920911814
Other languages
German (de)
English (en)
Other versions
EP0584212A1 (fr
Inventor
Edward Abraham
Yi-Han Chang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California Berkeley
University of California San Diego UCSD
Original Assignee
University of California Berkeley
University of California San Diego UCSD
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of California Berkeley, University of California San Diego UCSD filed Critical University of California Berkeley
Publication of EP0584212A1 publication Critical patent/EP0584212A1/fr
Publication of EP0584212A4 publication Critical patent/EP0584212A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/09Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092Streptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/104Pseudomonadales, e.g. Pseudomonas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • A61K2039/543Mucosal route intranasal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55522Cytokines; Lymphokines; Interferons
    • A61K2039/55527Interleukins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55555Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
EP19920911814 1991-05-13 1992-05-13 Vaccins comprenant un polysaccharide encapsule dans un liposome. Withdrawn EP0584212A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69914491A 1991-05-13 1991-05-13
US699144 1991-05-13

Publications (2)

Publication Number Publication Date
EP0584212A1 EP0584212A1 (fr) 1994-03-02
EP0584212A4 true EP0584212A4 (fr) 1994-11-30

Family

ID=24808131

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19920911814 Withdrawn EP0584212A4 (fr) 1991-05-13 1992-05-13 Vaccins comprenant un polysaccharide encapsule dans un liposome.

Country Status (8)

Country Link
EP (1) EP0584212A4 (fr)
JP (1) JPH07500813A (fr)
AU (1) AU665762B2 (fr)
CA (1) CA2109316A1 (fr)
FI (1) FI934866L (fr)
HU (1) HUT67159A (fr)
NO (1) NO934106L (fr)
WO (1) WO1992020370A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0708656B1 (fr) * 1993-04-27 2002-07-31 United Biomedical, Inc. Peptides immunogenes de la lhrh et stimulators d'immunite universelle de synthese pour vaccins
FR2716373B1 (fr) * 1994-02-23 1996-05-03 Pasteur Institut Liposomes, et leur utilisation pour l'obtention de vaccins.
WO1998040062A1 (fr) * 1997-03-11 1998-09-17 Stichting Dienst Landbouwkundig Onderzoek Utilisation de liposomes contenant un agent chelateur, un fongicide ou un secropine pour ameliorer la vaccination muqueuse
US6749831B1 (en) 1997-05-16 2004-06-15 Medical Defense Technology, Llc Vaccine against lipopolysaccharide core
US7534442B2 (en) 2001-08-21 2009-05-19 The Brigham And Women's Hospital, Inc. Immunogenic compositions comprising covalently bound polysaccharides, antigen, and bacterial toxoid
EP1928418B1 (fr) 2005-09-30 2011-12-21 Lipoxen Technologies Limited Compositions vaccinales liposomales comprenant un antigene polysaccharide et un adjuvant proteique
GB2548848A (en) * 2016-03-30 2017-10-04 The Inst Of Food Res Levan polysaccharide to modulate cell function

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0017557A2 (fr) * 1979-03-26 1980-10-15 Merck & Co. Inc. Particule de liposome contenant des sous-unités virales ou bactériennes antigéniques et procédé de préparation
WO1991001143A1 (fr) * 1989-07-14 1991-02-07 Praxis Biologics, Inc. Compositions de vaccin stable contenant des interleukines

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0017557A2 (fr) * 1979-03-26 1980-10-15 Merck & Co. Inc. Particule de liposome contenant des sous-unités virales ou bactériennes antigéniques et procédé de préparation
WO1991001143A1 (fr) * 1989-07-14 1991-02-07 Praxis Biologics, Inc. Compositions de vaccin stable contenant des interleukines

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
ABRAHAM I. ET AL.: "Oral immunization with bacterial polysaccharide and adjuvant enhances antigen-specific pulmonary secretory antibody response and resistance to pneumonia", VACCINE, vol. 9, no. 10, October 1991 (1991-10-01), GUILDFORD GB, pages 757 - 764 *
MBAWUIKE I.N. ET AL.: "Enhancement of the protective efficacity of inactivated influenza A virus vaccine in aged mice by IL-2 liposomes", VACCINE, vol. 8, no. 4, August 1990 (1990-08-01), GUILDFORD GB, pages 347 - 352 *
See also references of WO9220370A1 *

Also Published As

Publication number Publication date
NO934106L (no) 1994-01-12
WO1992020370A1 (fr) 1992-11-26
NO934106D0 (no) 1993-11-12
HU9303207D0 (en) 1994-03-28
FI934866A7 (fi) 1993-11-12
FI934866L (fi) 1993-11-12
AU1902992A (en) 1992-12-30
HUT67159A (en) 1995-02-28
CA2109316A1 (fr) 1992-11-14
FI934866A0 (fi) 1993-11-03
AU665762B2 (en) 1996-01-18
JPH07500813A (ja) 1995-01-26
EP0584212A1 (fr) 1994-03-02

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 19931213

AK Designated contracting states

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A4 Supplementary search report drawn up and despatched

Effective date: 19941013

AK Designated contracting states

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17Q First examination report despatched

Effective date: 19970924

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 19980205