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EP0551400A4 - Method for treating inflammation using anti-idiotypic antibodies - Google Patents

Method for treating inflammation using anti-idiotypic antibodies

Info

Publication number
EP0551400A4
EP0551400A4 EP19910918758 EP91918758A EP0551400A4 EP 0551400 A4 EP0551400 A4 EP 0551400A4 EP 19910918758 EP19910918758 EP 19910918758 EP 91918758 A EP91918758 A EP 91918758A EP 0551400 A4 EP0551400 A4 EP 0551400A4
Authority
EP
European Patent Office
Prior art keywords
idiotypic antibodies
treating inflammation
inflammation
treating
idiotypic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19910918758
Other languages
English (en)
Other versions
EP0551400A1 (fr
Inventor
Randall Barton
Michele 55 Wildman Street Czajkowski
Charles Kennedy
Robert Rothlein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharmaceuticals Inc
Original Assignee
Boehringer Ingelheim Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharmaceuticals Inc filed Critical Boehringer Ingelheim Pharmaceuticals Inc
Publication of EP0551400A1 publication Critical patent/EP0551400A1/fr
Publication of EP0551400A4 publication Critical patent/EP0551400A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2821Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against ICAM molecules, e.g. CD50, CD54, CD102
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4208Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
    • C07K16/4241Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig
    • C07K16/4258Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig against anti-receptor Ig
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
EP19910918758 1990-10-03 1991-10-02 Method for treating inflammation using anti-idiotypic antibodies Withdrawn EP0551400A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59214790A 1990-10-03 1990-10-03
US592147 1996-01-26

Publications (2)

Publication Number Publication Date
EP0551400A1 EP0551400A1 (fr) 1993-07-21
EP0551400A4 true EP0551400A4 (en) 1993-10-13

Family

ID=24369494

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19910918758 Withdrawn EP0551400A4 (en) 1990-10-03 1991-10-02 Method for treating inflammation using anti-idiotypic antibodies

Country Status (5)

Country Link
EP (1) EP0551400A4 (fr)
JP (1) JPH06504426A (fr)
AU (1) AU8765391A (fr)
CA (1) CA2092801A1 (fr)
WO (1) WO1992006119A1 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0362531B1 (fr) 1988-09-01 1999-11-10 Bayer Corporation Protéine du récepteur du rhinovirus humain, qui inhibe le caractère infectieux du virus
US6130202A (en) * 1990-07-20 2000-10-10 Bayer Corporation Antiviral methods
US6107461A (en) * 1990-07-20 2000-08-22 Bayer Corporation Multimeric forms of human rhinovirus receptor and fragments thereof, and method of use
US5891841A (en) * 1991-06-11 1999-04-06 The Center For Blood Research, Inc. Methods of using intercellular adhesion molecule-3 (ICAM-3), antibodies thereto, and soluble fragments thereof
WO1993014776A1 (fr) * 1992-01-27 1993-08-05 Icos Corporation Proteine apparentee a icam
US5837822A (en) * 1992-01-27 1998-11-17 Icos Corporation Humanized antibodies specific for ICAM related protein
US5811517A (en) * 1992-01-27 1998-09-22 Icos Corporation ICAM-related protein variants
US6818743B1 (en) 1992-01-27 2004-11-16 Icos Corporation I-CAM related protein
US6153395A (en) * 1992-01-27 2000-11-28 Icos Corporation ICAM-related protein
US6100383A (en) * 1992-01-27 2000-08-08 Icos Corporation Fusion proteins comprising ICAM-R polypeptides and immunoglobulin constant regions
US5532127A (en) * 1992-01-27 1996-07-02 Icos Corporation Assay for 1-CAM related protein expression
US5989843A (en) * 1992-01-27 1999-11-23 Icos Corporation Methods for identifying modulators of protein kinase C phosphorylation of ICAM-related protein
US5525487A (en) * 1992-01-27 1996-06-11 Icos Corporation DNA encoding I-CAM related protein
FR2858326A1 (fr) * 2003-08-01 2005-02-04 Abtech Procede de preparation d'anticorps mimetiques d'une substance et les anticorps ainsi obtenus

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4918164A (en) * 1987-09-10 1990-04-17 Oncogen Tumor immunotherapy using anti-idiotypic antibodies
ATE79270T1 (de) * 1989-03-09 1992-08-15 Boehringer Ingelheim Pharma Verwendung von interzellularen adhaesionsmolek¨len und deren bindungsliganden bei der behandlung von asthma.

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
IMMUNOLOGY vol. 67, no. 4, August 1989, OXFORD, GB pages 525 - 530 E. AUSTIN ET AL. 'Human monoclonal anti-idiotypic antibody to the tumour-associated antibody 791T/36.' *
JOURNAL OF IMMUNOLOGY, vol. 143, no. 4, 15 August 1989; BARTON et al., pp. 1278-1282/ *
MOLECULAR IMMUNOLOGY vol. 26, no. 12, 1989, OXFORD, GB pages 1155 - 1167 J. HILDRETH ET AL. 'Production and characterization of monoclonal anti-CD18 anti-idiotype antibodies.' *
SCIENCE, vol. 247, 26 January 1990; WEGNER et al., pp. 456-459/ *
See also references of WO9206119A1 *

Also Published As

Publication number Publication date
AU8765391A (en) 1992-04-28
EP0551400A1 (fr) 1993-07-21
JPH06504426A (ja) 1994-05-26
WO1992006119A1 (fr) 1992-04-16
CA2092801A1 (fr) 1992-04-04

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Legal Events

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