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EP0463004A4 - Metabolic effects of leukaemia inhibitory factor on bone - Google Patents

Metabolic effects of leukaemia inhibitory factor on bone

Info

Publication number
EP0463004A4
EP0463004A4 EP19900904185 EP90904185A EP0463004A4 EP 0463004 A4 EP0463004 A4 EP 0463004A4 EP 19900904185 EP19900904185 EP 19900904185 EP 90904185 A EP90904185 A EP 90904185A EP 0463004 A4 EP0463004 A4 EP 0463004A4
Authority
EP
European Patent Office
Prior art keywords
bone
inhibitory factor
metabolic effects
leukaemia inhibitory
leukaemia
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19900904185
Other versions
EP0463004A1 (en
Inventor
Donald Metcalf
Ian Reginald Reid
Thomas John Martin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CSL Innovation Pty Ltd
Original Assignee
Amrad Corp Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amrad Corp Ltd filed Critical Amrad Corp Ltd
Publication of EP0463004A1 publication Critical patent/EP0463004A1/en
Publication of EP0463004A4 publication Critical patent/EP0463004A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/20Interleukins [IL]
    • A61K38/2093Leukaemia inhibitory factor [LIF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP19900904185 1989-03-07 1990-03-06 Metabolic effects of leukaemia inhibitory factor on bone Withdrawn EP0463004A4 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
AU3091/89 1989-03-07
AUPJ309189 1989-03-07
AU4742/89 1989-06-15
AUPJ474289 1989-06-15

Publications (2)

Publication Number Publication Date
EP0463004A1 EP0463004A1 (en) 1992-01-02
EP0463004A4 true EP0463004A4 (en) 1992-04-01

Family

ID=25643646

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19900904185 Withdrawn EP0463004A4 (en) 1989-03-07 1990-03-06 Metabolic effects of leukaemia inhibitory factor on bone

Country Status (5)

Country Link
EP (1) EP0463004A4 (en)
JP (1) JP3055802B2 (en)
CA (1) CA2048673A1 (en)
NZ (1) NZ232826A (en)
WO (1) WO1990010454A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL97779A (en) * 1990-04-10 2000-01-31 Genentech Inc Compositions for cytoprotection against radiation and chemotherapy injury or risk thereof
WO1994021272A1 (en) * 1993-03-17 1994-09-29 Amrad Corporation Limited A method for treating microbial infection in an animal by administering a composition comprising lif and a cytokine
ATE262918T1 (en) * 1999-09-30 2004-04-15 Kaken Pharma Co Ltd PRODUCTION OF A MEDICATION FOR IMPROVED HEALING OF THE STERNUM AFTER A STERNOTOMY
WO2014138628A1 (en) 2013-03-07 2014-09-12 Case Western Reserve University Bioadhesive hydrogel
US11273236B2 (en) 2016-09-07 2022-03-15 Case Western Reserve University Engineered tissue constructs
EP3551199A4 (en) * 2016-12-11 2020-07-22 Case Western Reserve University COMPOSITIONS AND METHODS FOR MODULATING ENDOCHONDRAL OSSIFICATION AND BONE FORMATION
EP3672650A4 (en) 2017-08-21 2021-05-26 Case Western Reserve University HYDROGEL FOR TISSUE ENGINEERING AND BIO-PRINTING
US11191871B2 (en) 2018-03-30 2021-12-07 Case Western Reserve University Particulate coated hydrogel microparticles

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4438032A (en) * 1981-01-30 1984-03-20 The Regents Of The University Of California Unique T-lymphocyte line and products derived therefrom
US4675295A (en) * 1981-10-28 1987-06-23 Denki Kagaku Kogyo Kabushiki Kaisha Process for producing subculturable lymphokine-producing human T cell hybridomas
AU609128B2 (en) * 1987-04-02 1991-04-26 Amrad Operations Pty. Limited Leukaemia-inhibitory factor

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JOURNAL OF BONE AND MINERAL RESEARCH, vol. 3, no. 6, December 1988, pages 635-645, Mary Ann Liebert, Inc., New York, US; E. ABE et al.: "A differentiation-inducing factor produced by the osteoblastic cell line MC3T3-E1 stimulates bone resorption by promoting osteoclast formation" *
See also references of WO9010454A1 *

Also Published As

Publication number Publication date
JPH04503958A (en) 1992-07-16
WO1990010454A1 (en) 1990-09-20
JP3055802B2 (en) 2000-06-26
NZ232826A (en) 1992-09-25
EP0463004A1 (en) 1992-01-02
CA2048673A1 (en) 1990-09-08

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

AK Designated contracting states

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Designated state(s): AT BE CH DE DK ES FR GB IT LI LU NL SE

17P Request for examination filed

Effective date: 19911204

A4 Supplementary search report drawn up and despatched

Effective date: 19920207

AK Designated contracting states

Kind code of ref document: A4

Designated state(s): AT BE CH DE DK ES FR GB IT LI LU NL SE

17Q First examination report despatched

Effective date: 19940126

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 19940607