EP0341304A4 - Improved ricin molecules and ricin toxin conjugates - Google Patents

Improved ricin molecules and ricin toxin conjugates

Info

Publication number: EP0341304A4
Authority: EP; European Patent Office
Prior art keywords: ricin; improved; molecules; toxin conjugates; ricin toxin
Prior art date: 1987-11-24
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP19890900542

Other versions

EP0341304A1 (en

Inventor

Eugene L. Brown

Simon Jones

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Genetics Institute LLC

Original Assignee

Genetics Institute LLC

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-11-24

Filing date

1988-11-23

Publication date

1991-01-30

1988-11-23 Application filed by Genetics Institute LLC filed Critical Genetics Institute LLC

1989-11-15 Publication of EP0341304A1 publication Critical patent/EP0341304A1/en

1991-01-30 Publication of EP0341304A4 publication Critical patent/EP0341304A4/en

Status Withdrawn legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
- C07K14/42—Lectins, e.g. concanavalin, phytohaemagglutinin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Botany (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

EP19890900542 1987-11-24 1988-11-23 Improved ricin molecules and ricin toxin conjugates Withdrawn EP0341304A4 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US12473587A	1987-11-24	1987-11-24
US124735		1993-09-21

Publications (2)

Publication Number	Publication Date
EP0341304A1 EP0341304A1 (en)	1989-11-15
EP0341304A4 true EP0341304A4 (en)	1991-01-30

Family

ID=22416566

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP19890900542 Withdrawn EP0341304A4 (en)	1987-11-24	1988-11-23	Improved ricin molecules and ricin toxin conjugates

Country Status (3)

Country	Link
EP (1)	EP0341304A4 (en)
JP (1)	JPH02502287A (en)
WO (1)	WO1989004839A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IE912716A1 (en)	1990-08-14	1992-02-26	Res Dev Foundation	Protein Structure of the Plant Toxin Gelonin
AU5003597A (en) *	1996-10-28	1998-05-22	Medical University Of South Carolina	Methods and compositions for ricin fusion protein immunotoxins to treat cancer and autoimmune disease
US7247715B2 (en)	1997-04-30	2007-07-24	Twinstrand Therapeutics Inc.	Ricin-like toxin variants for treatment of cancer, viral or parasitic infections
AU7636800A (en)	1999-10-04	2001-05-10	Twinstrand Therapeutics Inc.	Improved ricin-like toxins for treatment of cancer
GB0022556D0 (en)	2000-09-14	2000-11-01	Oxoid Ltd	Improvements in or relating to selective agents for biological cultures
CA2601592A1 (en) *	2005-03-15	2006-09-28	Allergan, Inc.	Modified clostridial toxins with enhanced targeting capabilities for endogenous clostridial toxin receptor systems

Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1988007081A1 (en) *	1987-03-12	1988-09-22	Cetus Corporation	Recombinant ricin toxin fragments

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US1984260A (en) *	1930-11-10	1934-12-11	Allen & Hanburys Ltd	Process for preparing liquids containing active principles or hormones from parathyroid glands
US4689401A (en) *	1986-03-06	1987-08-25	Cetus Corporation	Method of recovering microbially produced recombinant ricin toxin a chain
EP0866128A3 (en) *	1986-03-07	1998-12-16	Chiron Corporation	Recombinant ricin toxin

1988
- 1988-11-23 WO PCT/US1988/004238 patent/WO1989004839A1/en not_active Ceased
- 1988-11-23 JP JP1500239A patent/JPH02502287A/en active Pending
- 1988-11-23 EP EP19890900542 patent/EP0341304A4/en not_active Withdrawn

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1988007081A1 (en) *	1987-03-12	1988-09-22	Cetus Corporation	Recombinant ricin toxin fragments

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO8904839A1 *

Also Published As

Publication number	Publication date
JPH02502287A (en)	1990-07-26
EP0341304A1 (en)	1989-11-15
WO1989004839A1 (en)	1989-06-01

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Legal Events

Date	Code	Title	Description
1989-09-30	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
1989-11-15	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE CH DE FR GB IT LI LU NL SE
1990-01-17	17P	Request for examination filed	Effective date: 19891120
1991-01-30	A4	Supplementary search report drawn up and despatched	Effective date: 19901212
1991-01-30	AK	Designated contracting states	Kind code of ref document: A4 Designated state(s): AT BE CH DE FR GB IT LI LU NL SE
1991-06-26	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
1991-08-14	18D	Application deemed to be withdrawn	Effective date: 19910130