EP0210153A2 - Dispositif de transfert sans contact avec le milieu environnant d'une substance entre au moins deux récipients - Google Patents
Dispositif de transfert sans contact avec le milieu environnant d'une substance entre au moins deux récipients Download PDFInfo
- Publication number
- EP0210153A2 EP0210153A2 EP86850262A EP86850262A EP0210153A2 EP 0210153 A2 EP0210153 A2 EP 0210153A2 EP 86850262 A EP86850262 A EP 86850262A EP 86850262 A EP86850262 A EP 86850262A EP 0210153 A2 EP0210153 A2 EP 0210153A2
- Authority
- EP
- European Patent Office
- Prior art keywords
- collection container
- plunger
- cannula
- rod
- attached
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000000126 substance Substances 0.000 title description 7
- 239000007788 liquid Substances 0.000 claims abstract description 14
- 230000008878 coupling Effects 0.000 claims abstract description 5
- 238000010168 coupling process Methods 0.000 claims abstract description 5
- 238000005859 coupling reaction Methods 0.000 claims abstract description 5
- 230000000149 penetrating effect Effects 0.000 claims abstract description 5
- 239000008280 blood Substances 0.000 claims description 14
- 210000004369 blood Anatomy 0.000 claims description 14
- 239000003708 ampul Substances 0.000 claims description 13
- 238000007789 sealing Methods 0.000 claims description 8
- 238000006243 chemical reaction Methods 0.000 claims description 5
- 210000003462 vein Anatomy 0.000 claims description 5
- 239000012528 membrane Substances 0.000 claims description 4
- 210000004204 blood vessel Anatomy 0.000 claims description 3
- 238000001802 infusion Methods 0.000 claims description 2
- 238000012546 transfer Methods 0.000 description 9
- 239000000243 solution Substances 0.000 description 5
- 238000011109 contamination Methods 0.000 description 4
- 238000002347 injection Methods 0.000 description 4
- 239000007924 injection Substances 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- 238000000605 extraction Methods 0.000 description 3
- 231100000614 poison Toxicity 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 239000002574 poison Substances 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 208000030507 AIDS Diseases 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 238000002483 medication Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 230000007096 poisonous effect Effects 0.000 description 1
Images
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
- B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
- B01L2200/0657—Pipetting powder
Definitions
- the present invention relates to a device for transferring a liquid from a vessel e.g. a bloodvessel, a ampoule or the like to a collection container, both of which can be attached to each other via a connecting apparatus with a two sided cannula, where at least the collecting container is closed at one end by a sealing cap which can be penetrated by the cannula, the collection container being in the shape of a cylinder for a plunger equipped with consist of a transparent tube an axial penetrating canal.
- a vessel e.g. a bloodvessel, a ampoule or the like
- a collection container both of which can be attached to each other via a connecting apparatus with a two sided cannula, where at least the collecting container is closed at one end by a sealing cap which can be penetrated by the cannula, the collection container being in the shape of a cylinder for a plunger equipped with consist of a transparent tube an axial penetrating canal.
- the blood is mixed in a test tube with a citrate solution, after which the solution is transferred to a pipette up to a certain level.
- the pipette is placed in a holder with a length scale.
- US-4.037.464 an apparatus used as a plunger in the test tube
- the purpose of the present invention is to achieve an apparatus of the above mentioned type with which the substance can be transferred between different vessels, for example transfer of a blood sample from a blood vessel to a pipette, in a closed system without contamination risk, and which apparatus is simpleand inexpensive to produce. This has been achieved according to the invention
- FIGS 1-3 a conventional cannula set is shown which used for blood sample extracton according to the vacuum system.
- the set consists of a cannula case 1 one end of which is equipped with an attachment to a cannula with punctation points 3 and 4 at both ends.
- the cannula point 3 inside the case 1 is apporpriately surrounded by a self sealing membrane 5 in the form of a rubber cap which prevents blood leakage.
- a vein is punctured by the outer point 4 of the cannula 2, while the inner point 3 is used for puncturing the rubber stopper 7 to a collection container 6.
- the collection container 6 consists of a cylinder open at both ends, one end of which is sealed by a rubber stopper 7 intended to be punctured by the cannula 2.
- a plunger 8 is fitted, to which is attached a rod 9, e.g. a transparent pipette tube or the like both of which are provided with an axial penetrating canal 21.
- a rod 9 e.g. a transparent pipette tube or the like both of which are provided with an axial penetrating canal 21.
- the collection container 6 contains shoulders 10, which prevent the plunger 8 from being removed from the container 6.
- the free end of the pipette tube 9 away from the plunger 8 is closed with a stopper 11, for example a plug, and withit it a blood filter 12 is placed.
- a valve can be used which can open and close the passage in the pipette tube 9.
- Transfer of the blood-citrate mixture from the container 6 to the pipette 9 is accomplished by removing the stopper 11 and attaching the pipette 9 to a holder 13 (figure 4) by its upper part.
- the container 6 with blood-citrate solution is moved upward in the direction of the plunger 8, whereby a blood column is pressed up in the pipette 9.
- the pipette is fixed in the lower part of the holder 13 the pipette is fixed in the lower part of the holder in attachments 14 for that purpose, between which the pipette tube is gripped so that the tube is closed.
- both the pipette tube 9 and the collection container 6 can be discarded as a unit.
- FIG. 5-7 The exemplification shown in figures 5-7 is designed primarily for transfer of a liquid enclosed in an ampule 14 to the collection container 6 and thereafter fruther to its intended use, for example injection into a patient.
- the outer part of the cannula 2 equipped with a point 4 contains a self sealing membrane 15 in the form of a rubber cap, which seals the cannula point 4 after it has penetrated the ampule's 14 rubber stopper 16.
- the tube has a coupling member 17 on its end away from the plunger 8, to which a multi-ported valve is 18 is attachable.
- a flexible pressure equalization chamber 19 is attached to one of the valve's 18 connectors for equalization of the pressure in the ampule 14, when liquid is sucked up from it to the collection container 6.
- a non-wettable filter can be arranged in front of the pressure equalization chamber 19.
- the plunger 8 In use the plunger 8 is moved toward the rubber stopper 7, whereby teh valve 18 is adjusted to allow air from the collection container 6 to be transferred to the pressure equalization chamber 19. The valve 18 is then closed.
- the collection container 6 can now be attached to the ampule 14 via the cannula set 1, 2 and liquid can be transferred to the collection container 6 by moving the plunger 8 downwards away from the rubber stopper 7.
- the reduced pressure in the ampule 14 is so large that the pressure equalization chamber 19 is attached to the tube 9. Air can now rise up in the container 6, and be pressed by the plunger 8 up into the ampule 14 and achieve a pressure equalization in it. This procedure can be repeated when necessary.
- the collection container 6 can be designed as a delivery container for certain medications in powder form, for example freeze dried cell poisons, which are dissolved by teh liquid which is taken from the ampule 14.
- teh liquid which is taken from the ampule 14.
- a liquid or air pereable filter (not shown) can be placed in teh tube or attached to it.
- type teh valve 18 is appropriately permanently attached to the tube 9, as well as the pressure equalization chamber 19 to the valve.
Landscapes
- Health & Medical Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Sampling And Sample Adjustment (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- External Artificial Organs (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8503583A SE8503583L (sv) | 1985-07-24 | 1985-07-24 | Anordning for att i ett slutet system overfora en substans mellan atminstone tva kerl |
| SE8503583 | 1985-07-24 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP0210153A2 true EP0210153A2 (fr) | 1987-01-28 |
| EP0210153A3 EP0210153A3 (fr) | 1988-06-08 |
Family
ID=20360960
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP86850262A Withdrawn EP0210153A3 (fr) | 1985-07-24 | 1986-07-18 | Dispositif de transfert sans contact avec le milieu environnant d'une substance entre au moins deux récipients |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP0210153A3 (fr) |
| JP (1) | JPS6331671A (fr) |
| SE (1) | SE8503583L (fr) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0732766B2 (ja) * | 1990-09-26 | 1995-04-12 | テルモ株式会社 | 採血針 |
| JPH08126630A (ja) * | 1994-11-01 | 1996-05-21 | Terumo Corp | 採血器具および採血針 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE381577B (sv) * | 1974-06-24 | 1975-12-15 | Mediplast Ab | Anordning for overforing av en vetska, sasom blod fran en cylindrisk behallare till en pipett |
| US4192320A (en) * | 1977-07-28 | 1980-03-11 | Becton, Dickinson And Company | Adapter for syringe |
| US4266559A (en) * | 1979-04-02 | 1981-05-12 | American Hospital Supply Corporation | Blood sampler |
| DE3025800A1 (de) * | 1980-07-08 | 1982-02-04 | Helga 4130 Moers Ufermann | Vorrichtung zur blutentnahme und zur blutsenkung |
| US4392497A (en) * | 1980-12-02 | 1983-07-12 | Ghaussy Rahmat U | Erythrocyte sedimentation rate apparatus and method |
| SE8400288L (sv) * | 1984-01-20 | 1985-07-21 | Anders Edvard Trell | Anordning for tagning och settning av blodsenkeprov |
-
1985
- 1985-07-24 SE SE8503583A patent/SE8503583L/xx not_active Application Discontinuation
-
1986
- 1986-07-18 EP EP86850262A patent/EP0210153A3/fr not_active Withdrawn
- 1986-07-24 JP JP61174694A patent/JPS6331671A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6331671A (ja) | 1988-02-10 |
| SE8503583L (sv) | 1987-01-25 |
| EP0210153A3 (fr) | 1988-06-08 |
| SE8503583D0 (sv) | 1985-07-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): DE FR GB IT SE |
|
| PUAL | Search report despatched |
Free format text: ORIGINAL CODE: 0009013 |
|
| AK | Designated contracting states |
Kind code of ref document: A3 Designated state(s): DE FR GB IT SE |
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| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
| 18D | Application deemed to be withdrawn |
Effective date: 19881209 |
|
| RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: EKHOLMER, ERIK |