[go: up one dir, main page]

EP0293411A1 - Dispositif d'osteosynthese - Google Patents

Dispositif d'osteosynthese

Info

Publication number
EP0293411A1
EP0293411A1 EP19870907409 EP87907409A EP0293411A1 EP 0293411 A1 EP0293411 A1 EP 0293411A1 EP 19870907409 EP19870907409 EP 19870907409 EP 87907409 A EP87907409 A EP 87907409A EP 0293411 A1 EP0293411 A1 EP 0293411A1
Authority
EP
European Patent Office
Prior art keywords
bone
screw
screw holes
head
screws
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP19870907409
Other languages
German (de)
English (en)
Inventor
Joram Raveh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AO Technology AG
Original Assignee
Synthes AG Chur
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH470786A external-priority patent/CH669105A5/de
Priority claimed from CH35387A external-priority patent/CH672245A5/de
Application filed by Synthes AG Chur filed Critical Synthes AG Chur
Publication of EP0293411A1 publication Critical patent/EP0293411A1/fr
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
    • A61B17/68Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/80Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates
    • A61B17/8033Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates having indirect contact with screw heads, or having contact with screw heads maintained with the aid of additional components, e.g. nuts, wedges or head covers
    • A61B17/8038Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates having indirect contact with screw heads, or having contact with screw heads maintained with the aid of additional components, e.g. nuts, wedges or head covers the additional component being inserted in the screw head
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
    • A61B17/68Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/80Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates
    • A61B17/8033Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates having indirect contact with screw heads, or having contact with screw heads maintained with the aid of additional components, e.g. nuts, wedges or head covers
    • A61B17/8047Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates having indirect contact with screw heads, or having contact with screw heads maintained with the aid of additional components, e.g. nuts, wedges or head covers wherein the additional element surrounds the screw head in the plate hole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
    • A61B17/68Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/84Fasteners therefor or fasteners being internal fixation devices
    • A61B17/86Pins or screws or threaded wires; nuts therefor
    • A61B17/8605Heads, i.e. proximal ends projecting from bone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
    • A61B17/68Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/70Spinal positioners or stabilisers, e.g. stabilisers comprising fluid filler in an implant
    • A61B17/7059Cortical plates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
    • A61B17/68Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/80Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates
    • A61B17/8061Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates specially adapted for particular bones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
    • A61B17/68Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/80Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates
    • A61B17/8061Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates specially adapted for particular bones
    • A61B17/8071Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates specially adapted for particular bones for the jaw
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
    • A61B17/68Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/84Fasteners therefor or fasteners being internal fixation devices
    • A61B17/86Pins or screws or threaded wires; nuts therefor
    • A61B17/8695Washers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30767Special external or bone-contacting surface, e.g. coating for improving bone ingrowth

Definitions

  • the invention relates to an osteosynthetic device, in particular an internal fixator, consisting of an osteosynthesis plate with at least two screw holes and bone screws that can be inserted therein.
  • Fixation devices for osteosynthesis have been known for a long time. Most systems, however, do not allow a rigid, functionally stable fixation between the head of the bone screw and the osteosynthesis plate, which often results in bone resorption at the contact surface between the osteosynthesis plate and bone, with subsequent instability and loosening. With other rigid systems, the relative position of the plate and screws cannot be varied.
  • the invention seeks to remedy this.
  • the invention has for its object to combine the advantages of an external fixator with those of the internal plate osteosynthesis and to achieve long-term functionally stable anchoring of the implant, wherein the axial position of the bone screws relative to the osteosynthesis plate can be variable over a wide range.
  • the invention achieves the stated object with a device which has the features of claim 1.
  • the advantages achieved by the invention are essentially to be seen in the fact that, thanks to the device according to the invention, firstly, the stability of the implant increases with the length of time and the load, and secondly, the stability of the osteosynthesis no longer by pressing the plate against the bone, but by rigid fixation of the screw to the plate can be achieved. Additional advantages result from the rotatability of the screw head, which reduces the requirements for the directional accuracy of the holes for the bone screws. An additional advantage results if the bone contact surfaces of the device according to the invention are provided with a bio-inert, porous layer, because then a direct, interface-free bond is formed on the contact surface between the bone and the implant surface.
  • Fig. 1 shows a longitudinal section through an inventive
  • Fig. 2 shows a cross section along the line II-II in Figure 1;
  • FIG. 3 shows a side view of the osteosynthesis plate of the device according to the invention
  • Figure 4 illustrates a top view of the osteosynthesis plate
  • FIG. 5 shows a section parallel to FIG. 2, but at the level of a bone screw
  • FIG. 6 shows the screw head from FIG. 5, with the preferred, continuously decreasing cross section, on an enlarged scale
  • FIG. 7 shows a top view of the screw head from FIG. 6;
  • FIG. 8 shows a cross section through the bio-inert porous surface of the osteosynthesis plate or the hollow bone screw intended for bone contact
  • Figure 9 represents the equilibrium diagram for the binary mixture
  • Figure 10 represents the equilibrium diagram for the binary mixture
  • FIG. 11 shows a perspective view of two devices connected to an osteosynthetic device according to the invention
  • FIG. 12 shows a longitudinal section through the osteosynthesis plate according to FIG. 11;
  • FIG. 13 illustrates a perspective view of the slotted hollow cylinder serving as an insert
  • FIG. 14 shows a cross section analogous to FIG. 5 with a
  • Fig. 16 shows a cross section through an inventive
  • Fig. 17 shows a cross section through an inventive
  • Expansion screw with smooth outer cone shows a partial cross section through a device according to the invention with an additional, non-expandable bone screw
  • FIG. 19 shows the device according to the invention according to FIG. 18, the head of the additional, non-spreadable
  • Bone screw is shown in cross section
  • FIG. 20 shows a partial cross section through a device according to the invention with a slotted ball screw head
  • FIG. 21 shows further details of the expansion screw according to FIG. 20 in cross section
  • Fig. 26 shows a cross section through an inventive
  • FIG. 28 shows a partial cross section through a device according to the invention with a conical plate hole and a spherical-layer-shaped screw head;
  • FIG. 29 shows the device according to the invention according to FIG. 28 with a screw axis inclined with respect to the vertical.
  • FIG. 1 shows various aspects of an internal fixator according to the invention.
  • the bone screws 3, as shown in the second screw hole from the left, are inserted into the screw holes 2 of the osteosynthesis plate 1 with their shaft 9 in screwed in the bone 4.
  • the screw head 7 is provided with longitudinal slots 10 and a bore 25, so that the insert 11, which is designed as an expansion screw with an external thread 14, can be screwed into the bore 25 provided with an internal thread 13 while the screw head 7 is widened.
  • the screwing in is expediently carried out by means of an instrument which engages in the longitudinal slots 12 of the insert 11.
  • the convex lateral surface 18 of the screw head 7 is wedged with the concave drilling wall 8 of the screw hole 2, which results in an extremely rigid connection between the osteosynthesis plate 1 and screw 3.
  • the osteosynthesis plate 1 has essentially no planar surface areas.
  • the profile 17 lying between the screw holes 2 is tapered on all sides and thus allows a simpler deformation of the osteosynthesis plate on the occasion of its adaptation to the bone surface 4.
  • the bending moment is preferably the between the screw holes 2 lying profile 17 smaller or the same size as that of the profile running through the screw holes 2.
  • the concave configuration of the drilling wall 8 can either be realized, as shown in FIGS. 1, 5 and 15, by appropriate shaping of the screw holes 2 or, as shown in FIGS. 13 and 14, by inserting a correspondingly designed hollow cylinder 19 into the cylindrical bore 20 of the osteosynthesis plate 1, the axial insertion of the hollow cylinder 19 being limited and secured by an edge 21 which is oversized in relation to the diameter of the bore 20.
  • the hollow cylinder 19 can either be made of metal, for example titanium, or can also consist of a deformable material, for example a plastic such as polyethylene (HMPE), under the action of the head 7 of the bone screw 3 screwed and spread into the screw hole 2.
  • HMPE polyethylene
  • the outer surface 22 of the hollow cylinder 19, as shown in FIG. 13, has one or more slots 23 in the lower zone adjacent to the bone contact surface 4 and is slightly undersized in diameter compared to the cylindrical bore 20 of the osteosynthesis plate 1.
  • the slots 23 can also be made in the upper zone adjacent to the edge 21.
  • the two parts 4a, 4b are through an osteosynthesis plate 1 connected to each other, which can be screwed with a solid core shaft 9 having bone screws 3 through the screw holes 2 to the bone 4, the pure titanium osteosynthesis plate 1 being bent manually with the usual surgical instruments and adapted to the bone relief 4.
  • the osteosynthesis plate 1 has essentially no planar surface parts and the profile 17 lying between the screw holes 2 is tapered on all sides.
  • the holes in the bone 4 for the bone screws 3 are made in accordance with the usual surgical technique, expediently using a drilling jig.
  • the screw hole 2 has a cross-sectional constriction 5 in the direction of the bone contact surface 4, which is designed as a stop 6 for the bone screw 3 and allows exact axial positioning and securing.
  • the screwing in of the bone screws 3 can take place by means of an instrument which engages in the longitudinal slots 10 and bore 25 of the screw head 7.
  • the conical threaded expansion bolts 11 are screwed in, which have longitudinal slots 12 on the outer, larger end, which serve to receive the screwing instrument (screwdriver).
  • the preferably conical internal thread 13 of the screw head 7 corresponds to the external thread 14 of the insert 11.
  • the osteosynthesis plate 1 can be removed again, the inserts 11 being unscrewed first and then the bone screws 3.
  • an implant in particular a joint endoprosthesis, for example a temporomandibular joint prosthesis, the bone screws 3 and the osteosynthesis plate 1, to which the implant is then connected, remain permanently in the body of the implant
  • the bone screws 3 can be designed as hollow screws in order to promote the ingrowth of bone tissue.
  • Those surfaces of the bone screws 3 which are intended for contact with the bone 4 have a bio-inert, porous layer 16.
  • This porous layer can either consist, as shown in FIG. 8, of titanium or its alloys, which is applied using a plasma spray or similar process, or else be produced by sandblasting, for example with aluminum oxide particles. Electrolytic surface processes or coating with ceramic (apatite) are also suitable means of making the surface bone-friendly.
  • Achieving a porous titanium layer with an adhesive strength of at least 9.5 kp / mm 2 , preferably of at least 12.0 kp / mm 2, has proven to be important for the desired success proven on the preferably metallic substrate.
  • adhesive strengths of at least 20 kp / mm 2 , preferably at least 40 kp / mm 2 can be achieved.
  • a suitable method for achieving such adhesive strengths is the plasma flame method, but other chemical methods are also suitable.
  • the coating of the internal fixator according to the invention with the bio-inert, porous layer can be done, for example, by spraying on titanium powder with a grain size distribution of approximately 0.05-0.1 mm in a gas mixture of nitrogen and hydrogen flowing out under high pressure in an electric arc at a temperature of 15 ' 000 to 20,000 ° C take place.
  • the titanium hydride particles supplied in an inert gas carrier for example argon, reach a speed of about 600 m / s within the 15 to 20 cm long acceleration distance at which they hit the metal surface to be coated and there a 0.01 depending on the duration of the process - Form 0.50 mm, preferably 0.03 - 0.06 mm thick, bio-inert, porous layer.
  • the coating is expediently carried out in such a way that the resulting pores have a diameter of approximately 30-200 ⁇ m, preferably approximately 40-70 ⁇ m.
  • the chemical composition of the coating is also important for the bio-inert properties.
  • Porous surface layers have proven to be advantageous which, in addition to the base material (titanium, Ti-6Al-4V etc.), have a carbon content of less than 0.5% (preferably less than 0.3%) and a nitrogen content of less than 4% ( preferably less than 3%) and have an oxygen content between 8-10% (all figures are in% by weight).
  • the titanium in the titanium plasma layer is expediently at least in the form of the hexagonally coordinated ⁇ -Ti and the cubically coordinated 6-TiO and 5-TiN, preferably in a proportion of 76-87% by weight of the hexagonally coordinated ⁇ -Ti.
  • the corresponding phases are from the two equilibrium diagrams shown in FIGS. 9 and 10 for the binary alloys O-Ti (FIG. 9; source: THSchofield and AEBacon, J. Inst. Metals, 1955/6. 84.47) and N- Ti (Fig. 10; source: AE Pally et al. Trans.Amer -Soc.Met., 1954, 46, 312).
  • the preferred material titanium alloys, zirconium, Siobium, tantalum or platinum.
  • the osteosynthesis plate 1 can be removed again, the inserts 11 being unscrewed first and then the bone screws 3.
  • the internal fixator according to the invention is used to fix an implant, in particular a joint endoprosthesis, for example a temporomandibular joint prosthesis, the bone screws 3 and that remain Osteosynthesis plate 1 to which the implant then connects continuously in the patient's body.
  • Bio-inert, preferably reinforced plastic materials can also be used as the osteosynthesis plate 1 for the internal fixator according to the invention, for example in the form of deformable, polymerizable composite structures as described in Swiss patent application No. 03 428 / 86-1.
  • the internal fixator according to the invention is particularly suitable in maxillofacial surgery and for the fixation of endogenous prostheses and vertebral plates.
  • osteosynthesis plates with the usual dimensions have proven to be unsuitable.
  • Osteosynthesis plates 1 which have the following dimensions, have proven to be particularly advantageous for these purposes:
  • the screw head 7 of the bone screws 3 to be used is also very small, the two threads 13, 14 are designed to be continuous at least in the upper part facing away from the bone contact surface 4, so that when the insert 11 is screwed in, it expands the head 7 takes place.
  • a shape of the screw head 7 according to FIG. 6 has proven to be particularly expedient.
  • the lateral surface 18 of the head 7 is increasingly convex only in the lower zone adjacent to the bone contact surface 4, while the upper part practically ends in a cylindrical shape.
  • an appropriately designed drilling wall 8 of the very dovetail hole 2 there is an optimal, rigid and functionally stable connection between the osteosynthesis plate 1 and the bone screw 3.
  • FIG. 16 Another variant of the screw head 7 is shown in FIG. 16.
  • the cylindrical screw head 7 fits into the corresponding cylindrical part of the drilling wall 8 of the screw hole 2.
  • the power transmission takes place between the screw head 7 and the axial stop 6 designed as a taper in the bore 2 of the osteosynthesis plate 1.
  • FIGS. 22-24 Further variants of this print run are shown in FIGS. 22-24.
  • the advantage of these variants is the maximum lateral and axial load capacity.
  • the insert 11 is designed as a conical expansion screw with an external thread 14 which fits the internal thread 13 of the screw head 7 provided with longitudinal slots 10.
  • the variant of the screw head 7 shown in FIG. 17 largely corresponds to the embodiment according to FIG. 16 with the exception of the insert 11, which is designed here as a cone with a smooth outer surface 27, which by means of the cylindrical screw attachment 28 with the likewise smooth outer shell 26 of the conical bore 25 in Screw head 7 can be jammed.
  • FIGS. 20 and 21 The variant of a slotted ball screw head 7 shown in FIGS. 20 and 21 has a further significant advantage, which consists in that, in addition to the rigid and releasable connection between the bone screw 3 and the osteosynthesis plate 1, the screw axis 30 is inclined by the angle ⁇ up to 30 ° to the screw hole axis 24 is possible.
  • the spherical bonnet head 7 provided with longitudinal slots 10 can be expanded and rigidly fixed by means of the insert 11 designed as an expanding screw.
  • FIGS. 22 to 25 show variants of the screw hole bores 2 according to the invention with various embodiments of the annular tapered part 6. In FIG.
  • FIG. 22 shows a variant of the embodiment according to FIG. 22, which consists in the step-shaped taper 6 being inclined downwards.
  • FIG. 24 shows a screw hole 2 which is analogous to FIG. 5, but which widens again in the lower part facing the bone.
  • FIG. 25 shows a spherically formed borehole wall 8 which is particularly suitable for ball screw heads 7 according to FIGS. 26 and 27.
  • FIGS. 25 and 27 correspond essentially to the embodiment shown in FIG. 21, but with a screw hole 2 according to FIG. 24 or 25 and an insert 11 designed as a conical screw bolt.
  • the slots 10 of the screw ball head 7 are slotted crosswise and milled so deep that there is sufficient mechanical strength, but the screw ball head 7 can be easily pressed into one of the various screw holes 2 according to FIGS. 22 to 25.
  • an axial deviation of the screw axis of up to 30 ° is possible.
  • a further advantage is the possibility of an inevitable forward and backward movement of the screw-plate connection.
  • FIGS. 25 and 27 correspond essentially to the embodiment shown in FIG. 21, but with a screw hole 2 according to FIG. 24 or 25 and an insert 11 designed as a conical screw bolt.
  • the slots 10 of the screw ball head 7 are slotted crosswise and milled so deep that there is sufficient mechanical strength, but the screw ball head 7 can be easily pressed into one of the various screw holes 2 according to FIGS. 22 to 25.
  • FIG. 27 and 28 shows an osteosynthetic plate 1 with a borehole wall 8 of the hole 2 designed as a cone, the cone angle ⁇ being between 2-6 °, preferably between 3 and 5 ° and being, for example, 4 °.
  • the screw 3 provided for this hole 2 has a head 7 which is essentially designed as a spherical layer with slots 10 and into which an expansion screw 7 can be screwed. Due to the inner shape of the borehole wall 8 and the outer shape of the screw head 7, a deviation of the screw axis 30 by the angle .alpha. Compared to the hole axis 24 is possible with a consistently good mounting, which considerably extends the application range of the device according to the invention.

Landscapes

  • Health & Medical Sciences (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Surgical Instruments (AREA)
  • Prostheses (AREA)

Abstract

Dans ce fixateur interne pour l'ostéosynthèse, les vis (3) peuvent être fixées de façon rigide et stable à une plaque de titane pur (1). Les parois d'alésage (8) des trous de vis (2) présentent dans au moins une zone voisine de la surface de contact (4) avec l'os une diminution (5) de la section, qui sert de butée (6) à la tête (7) de la vis (3). Cette tête (7) pourvue d'une fente longitudinale (10) et d'un alésage (25) peut être amenée en contact intime avec la plaque d'ostéosynthèse (1) en vissant un écarteur (11) dans la tête (7). La surface sphérique de la tête (7) et de l'alésage (8) permet un certain ajustement axial des vis (3) de façon que les exigences quant à la précision de l'alésage soient moins élevées. Les surfaces du fixateur interne, qui entrent en contact avec l'os (4), sont pourvues, de préférence, d'une couche poreuse (16) pour favoriser la croissance de l'os. Application de ce fixateur interne, outre pour l'ostéosynthèse proprement dite, pour la fixation d'implants, notamment d'endoprothèses articulatoires, par exemple de la mâchoire, de la hanche ou des vertèbres.
EP19870907409 1986-11-25 1987-11-25 Dispositif d'osteosynthese Ceased EP0293411A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CH470786A CH669105A5 (de) 1986-11-25 1986-11-25 Interne fixationsvorrichtung fuer die osteosynthese.
CH4707/86 1986-11-25
CH35387A CH672245A5 (en) 1987-02-02 1987-02-02 Inner osteosynthesis fastener with bone screws
CH353/87 1987-02-02

Publications (1)

Publication Number Publication Date
EP0293411A1 true EP0293411A1 (fr) 1988-12-07

Family

ID=25684311

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19870907409 Ceased EP0293411A1 (fr) 1986-11-25 1987-11-25 Dispositif d'osteosynthese

Country Status (3)

Country Link
EP (1) EP0293411A1 (fr)
JP (1) JPH02500490A (fr)
WO (1) WO1988003781A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USD734853S1 (en) 2009-10-14 2015-07-21 Nuvasive, Inc. Bone plate
US9615866B1 (en) 2004-10-18 2017-04-11 Nuvasive, Inc. Surgical fixation system and related methods

Families Citing this family (138)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7452359B1 (en) 1988-06-13 2008-11-18 Warsaw Orthopedic, Inc. Apparatus for inserting spinal implants
SE466936B (sv) * 1989-04-25 1992-05-04 Branemark Per Ingvar Foerankringselement foer uppbaerande av proteser
US5275601A (en) * 1991-09-03 1994-01-04 Synthes (U.S.A) Self-locking resorbable screws and plates for internal fixation of bone fractures and tendon-to-bone attachment
IT228979Y1 (it) * 1992-03-09 1998-06-05 Giannini Sandro Protesi biodegradabile per correzione retropiede pronato.
IT227861Y1 (it) * 1992-05-15 1998-01-21 Citieffe Srl Fiche per fissatori esterni
JP3308271B2 (ja) 1992-06-25 2002-07-29 ジンテーズ アクチエンゲゼルシャフト,クール 骨接合用固定装置
FR2695026B1 (fr) * 1992-08-25 1994-10-28 Alexandre Worcel Dispositif pour le maintien en compression d'un os fracturé.
ES2048671B1 (es) * 1992-09-07 1994-10-01 Alacreu Jose Vicente Barbera Sistema de fusion vertebral cervical.
DE69320593T2 (de) * 1992-11-25 1999-03-04 Codman & Shurtleff, Inc., Randolph, Mass. Knochenplattensystem
US5534027A (en) * 1993-06-21 1996-07-09 Zimmer, Inc. Method for providing a barrier to the advancement of wear debris in an orthopaedic implant assembly
SE9402130D0 (sv) * 1994-06-17 1994-06-17 Sven Olerud Anordning samt förfarande för plattfixation av ben
US5681311A (en) * 1994-09-15 1997-10-28 Smith & Nephew, Inc. Osteosynthesis apparatus
JPH11504227A (ja) * 1994-09-15 1999-04-20 スミス アンド ネフュー インコーポレーテッド 骨接合装置
CA2199637C (fr) 1994-09-15 2007-05-01 Paul W. Pavlov Cage de fusion anterieure de forme conique et procede d'implantation
FR2726171B1 (fr) * 1994-10-28 1997-01-24 Jbs Sa Dispositif de vis de liaison rehabitable pour articulation osseuse, destine notamment a la stabilisation d'au moins deux vertebres
SE509703C2 (sv) * 1995-02-07 1999-03-01 Sven Olerud Två anordningar för låsning av två implantatelement till varandra
EP0760632B1 (fr) * 1995-03-27 2000-09-13 Synthes AG, Chur Plaque pour osteosynthese
US5520690A (en) * 1995-04-13 1996-05-28 Errico; Joseph P. Anterior spinal polyaxial locking screw plate assembly
AU6459496A (en) * 1995-07-13 1997-02-10 Fastenetix, L.L.C. A polyaxial locking mechanism
DE29521456U1 (de) * 1995-12-07 1997-05-07 Aesculap Ag, 78532 Tuttlingen Orthopädisches Haltesystem
AU1997797A (en) * 1996-05-31 1997-12-04 Acromed Corporation An apparatus comprising a plate and a fastener for connecting the plate to a bone portion
FR2753368B1 (fr) 1996-09-13 1999-01-08 Chauvin Jean Luc Cage d'osteosynthese expansive
DE69838856T2 (de) * 1997-02-11 2008-12-11 Warsaw Orthopedic, Inc., Warsaw Platte für die vordere Halswirbelsäule mit Fixierungssystem für eine Schraube
AU6145998A (en) 1997-02-11 1998-08-26 Gary Karlin Michelson Skeletal plating system
US6641614B1 (en) 1997-05-01 2003-11-04 Spinal Concepts, Inc. Multi-variable-height fusion device
US5954722A (en) * 1997-07-29 1999-09-21 Depuy Acromed, Inc. Polyaxial locking plate
US6454769B2 (en) 1997-08-04 2002-09-24 Spinal Concepts, Inc. System and method for stabilizing the human spine with a bone plate
WO1999059492A1 (fr) 1998-05-19 1999-11-25 Synthes Ag Chur Implant osteosynthetique dote d'un assemblage articule encastre
JP2002523129A (ja) * 1998-08-21 2002-07-30 ジンテーズ アクチエンゲゼルシャフト クール スナップ嵌め可能な球形頭部を有する骨固定要素
ATE219646T1 (de) 1998-08-21 2002-07-15 Synthes Ag Selbstschneidendes hohlzylindrisches knochenverankerungselement
US6554834B1 (en) 1999-10-07 2003-04-29 Stryker Spine Slotted head pedicle screw assembly
US6331179B1 (en) 2000-01-06 2001-12-18 Spinal Concepts, Inc. System and method for stabilizing the human spine with a bone plate
CA2407009C (fr) 2000-04-19 2007-01-23 Synthes (U.S.A.) Dispositif permettant la connexion articulee de deux corps
US8177841B2 (en) 2000-05-01 2012-05-15 Arthrosurface Inc. System and method for joint resurface repair
US6610067B2 (en) 2000-05-01 2003-08-26 Arthrosurface, Incorporated System and method for joint resurface repair
US6520964B2 (en) 2000-05-01 2003-02-18 Std Manufacturing, Inc. System and method for joint resurface repair
AU2005202099B2 (en) * 2000-05-01 2007-06-07 Arthrosurface, Incorporated System and method for joint resurface repair
ATE326180T1 (de) * 2000-05-31 2006-06-15 Vese Silvana Befestigungsvorrichtung für knochenplatte
US6485491B1 (en) * 2000-09-15 2002-11-26 Sdgi Holdings, Inc. Posterior fixation system
US6776781B1 (en) * 2000-09-28 2004-08-17 Farihan Renno Spinal-column buttress plate assembly and method for attachment
DE10055888C1 (de) 2000-11-10 2002-04-25 Biedermann Motech Gmbh Knochenschraube
US7578825B2 (en) 2004-04-19 2009-08-25 Acumed Llc Placement of fasteners into bone
US7090676B2 (en) 2002-11-19 2006-08-15 Acumed Llc Adjustable bone plates
US7537604B2 (en) 2002-11-19 2009-05-26 Acumed Llc Bone plates with slots
GB2375051B (en) * 2001-05-02 2005-04-06 Biomet Merck Ltd Swivel coupling
US6974460B2 (en) 2001-09-14 2005-12-13 Stryker Spine Biased angulation bone fixation assembly
US6755833B1 (en) 2001-12-14 2004-06-29 Kamaljit S. Paul Bone support assembly
US7070599B2 (en) 2002-07-24 2006-07-04 Paul Kamaljit S Bone support assembly
USD505205S1 (en) 2002-02-01 2005-05-17 Spinal Concepts, Inc. Bone plate system extender plate
EP1482877B1 (fr) 2002-03-11 2007-05-30 Spinal Concepts Inc. Equipement pour l'installation d'implants vertebraux
US7001389B1 (en) 2002-07-05 2006-02-21 Navarro Richard R Fixed and variable locking fixation assembly
EP1542602B1 (fr) 2002-07-22 2010-11-17 Acumed LLC Systeme de fusion osseuse
NL1021137C2 (nl) * 2002-07-23 2004-01-27 Fondel Finance B V Steunelement voor bevestiging aan bot.
DE10246386B4 (de) 2002-10-04 2008-08-07 Biedermann Motech Gmbh Knochenschraube, Knochenfixationseinrichtung und Halteelement
AU2003294342A1 (en) 2002-11-19 2004-06-15 Acumed Llc Guide system for bone-repair devices
GB2412875A (en) 2002-11-19 2005-10-12 Acumed Llc Deformable bone plates
US7914545B2 (en) 2002-12-03 2011-03-29 Arthrosurface, Inc System and method for retrograde procedure
EP1433426A1 (fr) * 2002-12-24 2004-06-30 JB Spine Instruments, S.l. Dispositif de fixation postérieure pour les corps vertébrales lombaires
US8388624B2 (en) 2003-02-24 2013-03-05 Arthrosurface Incorporated Trochlear resurfacing system and method
US7278997B1 (en) 2003-03-07 2007-10-09 Theken Spine, Llc Instrument guide and implant holder
US7951176B2 (en) 2003-05-30 2011-05-31 Synthes Usa, Llc Bone plate
GB2419096B (en) 2003-06-20 2008-03-19 Acumed Llc Bone plates with intraoperatively tapped apertures
US11259851B2 (en) 2003-08-26 2022-03-01 DePuy Synthes Products, Inc. Bone plate
BR0318428A (pt) 2003-08-26 2006-08-01 Synthes Gmbh placa de osso
US7635365B2 (en) 2003-08-28 2009-12-22 Ellis Thomas J Bone plates
DE50308440D1 (de) 2003-09-08 2007-11-29 Synthes Gmbh Vorrichtung zur knochenfixation
CA2545019C (fr) 2003-10-30 2012-02-28 Synthes Gmbh Plaque d'osteosynthese
US7846190B2 (en) 2003-12-12 2010-12-07 Integra Lifesciences Corporation Apparatuses, systems and methods for bone fixation
US8574268B2 (en) 2004-01-26 2013-11-05 DePuy Synthes Product, LLC Highly-versatile variable-angle bone plate system
US7637928B2 (en) 2004-01-26 2009-12-29 Synthes Usa, Llc Variable angle locked bone fixation system
US11291484B2 (en) 2004-01-26 2022-04-05 DePuy Synthes Products, Inc. Highly-versatile variable-angle bone plate system
US8900277B2 (en) 2004-02-26 2014-12-02 Pioneer Surgical Technology, Inc. Bone plate system
US7311712B2 (en) * 2004-02-26 2007-12-25 Aesculap Implant Systems, Inc. Polyaxial locking screw plate assembly
US7740649B2 (en) 2004-02-26 2010-06-22 Pioneer Surgical Technology, Inc. Bone plate system and methods
US7963981B2 (en) * 2004-04-19 2011-06-21 Globus Medical, Inc. Bone fixation plate
CA2572584A1 (fr) 2004-06-28 2006-01-12 Arthrosurface, Inc. Systeme de remplacement de surface articulaire
KR100612621B1 (ko) * 2004-07-07 2006-08-14 주식회사 지에스메디칼 뼈 고정 장치 및 그 장치내의 로드를 연결하기 위한트랜스커넥터
WO2006034436A2 (fr) 2004-09-21 2006-03-30 Stout Medical Group, L.P. Dispositif de support expansible et procede d'utilisation
DE102004050040A1 (de) 2004-10-08 2006-04-20 Aesculap Ag & Co. Kg Knochenschraube
US7828853B2 (en) 2004-11-22 2010-11-09 Arthrosurface, Inc. Articular surface implant and delivery system
US7736380B2 (en) * 2004-12-21 2010-06-15 Rhausler, Inc. Cervical plate system
US20060235403A1 (en) 2005-03-17 2006-10-19 Jason Blain Flanged interbody fusion device with locking plate
US7883531B2 (en) * 2005-07-06 2011-02-08 Stryker Spine Multi-axial bone plate system
JP5081822B2 (ja) 2005-07-14 2012-11-28 スタウト メディカル グループ,エル.ピー. 拡張可能支持デバイスおよびシステム
US7766946B2 (en) 2005-07-27 2010-08-03 Frank Emile Bailly Device for securing spinal rods
JPWO2007043149A1 (ja) * 2005-10-05 2009-04-16 株式会社ホムズ技研 骨接合用インプラント及びその製造方法
US7320555B2 (en) * 2005-10-14 2008-01-22 Sercomm Corporation Cardan shaft structure with tightness adjustable functions
EP2023864B1 (fr) 2006-05-01 2019-07-10 Stout Medical Group, L.P. Dispositif de soutien expansible
US8021369B2 (en) 2006-06-12 2011-09-20 Howmedica Osteonics Corp. Navigated femoral neck resection guide and method
CA2686814A1 (fr) 2006-12-11 2008-06-19 Arthrosurface Incorporated Appareil de resection retrograde et procede
US8480715B2 (en) 2007-05-22 2013-07-09 Zimmer Spine, Inc. Spinal implant system and method
FR2917596B1 (fr) * 2007-06-21 2010-06-18 Newdeal Kit de fixation a usage medical ou chirurgical
US8361126B2 (en) 2007-07-03 2013-01-29 Pioneer Surgical Technology, Inc. Bone plate system
WO2009006604A1 (fr) 2007-07-03 2009-01-08 Pioneer Surgical Technology, Inc. Système de plaque vissée
WO2009111481A1 (fr) 2008-03-03 2009-09-11 Arthrosurface Incorporated Système de resurfaçage d'os et procédé
US8480716B2 (en) 2008-04-25 2013-07-09 Pioneer Surgical Technology, Inc. Bone plate system
US12285197B2 (en) 2008-10-10 2025-04-29 Acumed Llc Bone fixation system with opposed mounting portions
US20100204795A1 (en) 2008-11-12 2010-08-12 Stout Medical Group, L.P. Fixation device and method
US20100211176A1 (en) 2008-11-12 2010-08-19 Stout Medical Group, L.P. Fixation device and method
US9220547B2 (en) 2009-03-27 2015-12-29 Spinal Elements, Inc. Flanged interbody fusion device
US9283076B2 (en) 2009-04-17 2016-03-15 Arthrosurface Incorporated Glenoid resurfacing system and method
WO2016154393A1 (fr) 2009-04-17 2016-09-29 Arthrosurface Incorporated Système de réparation de glénoïde et ses méthodes d'utilisation
US9662126B2 (en) 2009-04-17 2017-05-30 Arthrosurface Incorporated Glenoid resurfacing system and method
US8568417B2 (en) 2009-12-18 2013-10-29 Charles River Engineering Solutions And Technologies, Llc Articulating tool and methods of using
EP2542165A4 (fr) 2010-03-05 2015-10-07 Arthrosurface Inc Système et procédé de resurfaçage tibial
US9149286B1 (en) 2010-11-12 2015-10-06 Flexmedex, LLC Guidance tool and method for use
US9066716B2 (en) 2011-03-30 2015-06-30 Arthrosurface Incorporated Suture coil and suture sheath for tissue repair
WO2013028808A1 (fr) 2011-08-23 2013-02-28 Flexmedex, LLC Dispositif et procédé d'ablation de tissu
EP2760354B1 (fr) 2011-09-30 2019-05-08 Acute Innovations, Llc Système de fixation osseuse ayant des parties de montage opposées
EP2804565B1 (fr) 2011-12-22 2018-03-07 Arthrosurface Incorporated Système pour une fixation osseuse
US9198769B2 (en) 2011-12-23 2015-12-01 Pioneer Surgical Technology, Inc. Bone anchor assembly, bone plate system, and method
WO2013113015A1 (fr) 2012-01-26 2013-08-01 Acute Innovations Llc Pince pour stabilisation de côte
WO2014008126A1 (fr) 2012-07-03 2014-01-09 Arthrosurface Incorporated Système et procédé de resurfaçage et de réparation d'articulation
US9492200B2 (en) 2013-04-16 2016-11-15 Arthrosurface Incorporated Suture system and method
FR3008886B1 (fr) * 2013-07-29 2015-09-11 Medacta Int Sa Composant acetabulaire pour une prothese de hanche de reconstruction de l'articulation de la hanche
US11607319B2 (en) 2014-03-07 2023-03-21 Arthrosurface Incorporated System and method for repairing articular surfaces
US10624748B2 (en) 2014-03-07 2020-04-21 Arthrosurface Incorporated System and method for repairing articular surfaces
US9962265B2 (en) 2014-03-07 2018-05-08 Arthrosurface Incorporated System and method for repairing articular surfaces
WO2015187937A1 (fr) 2014-06-04 2015-12-10 Wenzel Spine, Inc. Dispositif de fusion de corps intervertébral à extension bilatérale
JP6594946B2 (ja) 2014-07-03 2019-10-23 アキュームド・エルエルシー 移動可能な継手を備える骨プレート
EP3250155A4 (fr) 2015-01-27 2018-08-22 Spinal Elements Inc. Prothèse d'articulation facettaire
US11103294B2 (en) 2016-06-09 2021-08-31 Stryker European Operations Holdings Llc Bone screw system
US10820930B2 (en) 2016-09-08 2020-11-03 DePuy Synthes Products, Inc. Variable angle bone plate
US10624686B2 (en) 2016-09-08 2020-04-21 DePuy Synthes Products, Inc. Variable angel bone plate
US10905476B2 (en) 2016-09-08 2021-02-02 DePuy Synthes Products, Inc. Variable angle bone plate
US11160663B2 (en) 2017-08-04 2021-11-02 Arthrosurface Incorporated Multicomponent articular surface implant
US11026727B2 (en) 2018-03-20 2021-06-08 DePuy Synthes Products, Inc. Bone plate with form-fitting variable-angle locking hole
US10772665B2 (en) 2018-03-29 2020-09-15 DePuy Synthes Products, Inc. Locking structures for affixing bone anchors to a bone plate, and related systems and methods
US11013541B2 (en) 2018-04-30 2021-05-25 DePuy Synthes Products, Inc. Threaded locking structures for affixing bone anchors to a bone plate, and related systems and methods
CA3111008A1 (fr) 2018-09-20 2020-03-26 Spinal Elements, Inc. Dispositif d'implant rachidien
CN109330672B (zh) 2018-12-11 2024-04-12 北京爱康宜诚医疗器材有限公司 锁定钢板及具有其的锁定钢板组件
US10925651B2 (en) 2018-12-21 2021-02-23 DePuy Synthes Products, Inc. Implant having locking holes with collection cavity for shavings
US11478358B2 (en) 2019-03-12 2022-10-25 Arthrosurface Incorporated Humeral and glenoid articular surface implant systems and methods
US11219531B2 (en) 2019-04-10 2022-01-11 Wenzel Spine, Inc. Rotatable intervertebral spacing implant
US11877779B2 (en) 2020-03-26 2024-01-23 Xtant Medical Holdings, Inc. Bone plate system
WO2022109524A1 (fr) 2020-11-19 2022-05-27 Spinal Elements, Inc. Dispositifs intervertébraux extensibles incurvés et outils de déploiement
CN112662983B (zh) * 2020-12-04 2022-11-29 西部宝德科技股份有限公司 一种钛及钛合金表面多孔层的制备方法
WO2022133456A1 (fr) 2020-12-17 2022-06-23 Spinal Elements, Inc. Dispositif d'implant rachidien

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2254298A1 (en) * 1973-12-18 1975-07-11 Chatin Robert Osteosynthesis plate guide device - has eccentric screw guide members in fracture clamping plate
CH648197A5 (de) * 1980-05-28 1985-03-15 Synthes Ag Implantat und zu dessen befestigung an einem knochen dienende schrauben.
CH645264A5 (de) * 1980-05-28 1984-09-28 Straumann Inst Ag Einrichtung mit einer platte und zu deren befestigung an einem knochen dienenden schrauben.
DE8610858U1 (de) * 1986-04-21 1986-06-12 Wolter, Dietmar, Prof. Dr., 2000 Hamburg Knochenplattenanordnung

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO8803781A1 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9615866B1 (en) 2004-10-18 2017-04-11 Nuvasive, Inc. Surgical fixation system and related methods
USD734853S1 (en) 2009-10-14 2015-07-21 Nuvasive, Inc. Bone plate
USD754857S1 (en) 2009-10-14 2016-04-26 Nuvasive, Inc. Bone plate

Also Published As

Publication number Publication date
JPH02500490A (ja) 1990-02-22
WO1988003781A1 (fr) 1988-06-02

Similar Documents

Publication Publication Date Title
EP0293411A1 (fr) Dispositif d'osteosynthese
EP2335656B1 (fr) Implant intervertébral
DE68918939T2 (de) Prothese für hüftgelenk.
EP1476098B1 (fr) Implant intervertebral
CH675531A5 (en) Instrument for osteosynthesis with perforated plate - has convex head bone screws fitting in tapering holes in osteosynthesis plate
EP0795306B1 (fr) Prothèse osseuse modulaire comportant une cupule et des pointes
EP1024762B1 (fr) Dispositif d'osteosynthese
CH672245A5 (en) Inner osteosynthesis fastener with bone screws
DE69839011T2 (de) Vorrichtung zum anbringen von skelettplatten
DE2806414C3 (de) Platte für die Osteosynthese
DE3787674T2 (de) Modulsystem zur Fixierung des Femurs.
DE29823952U1 (de) Implantat zur Stabilisierung einer Fraktur
WO2000036984A1 (fr) Systeme de fixation pour os
EP1211993A1 (fr) Systeme de fixation pour os
DE102010048052A1 (de) Fixationsmittel für Knochen mit Vorrichtung zur polyaxialen winkelstabilen Schraubenfixation und Schrauben hierfür und Verfahren zur Fixation von Knochen
EP1168989B1 (fr) Prothese de tete d'articulation et pieces necessaires a sa realisation
EP2696783B1 (fr) Implant chirurgical destiné à élargir le canal vertébral
EP0013862A1 (fr) Plaque d'ostéosynthèse
DE10201743C2 (de) Intramedulläres Osteosyntheseimplantat
EP0423280A1 (fr) Systeme de fixation pour fractures d'os tubulaires.
EP1572018B1 (fr) Clou permettant de reparer des fractures osseuses
WO2002064066A2 (fr) Cotyle implantable pour des endoprotheses de l'articulation de la hanche
DE68907714T2 (de) Kniegelenksprothese.
EP4231946B1 (fr) Élément fileté optimisé pour l'impression 3d
DE2953575A1 (de) Hueftkopf-kappen-endoprothese

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 19880708

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH DE FR GB IT LI LU NL SE

17Q First examination report despatched

Effective date: 19910325

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: SYNTHES AG, CHUR

APAB Appeal dossier modified

Free format text: ORIGINAL CODE: EPIDOS NOAPE

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION HAS BEEN REFUSED

18R Application refused

Effective date: 19960301

APAF Appeal reference modified

Free format text: ORIGINAL CODE: EPIDOSCREFNE