EE200600044A - Antisens-oligonukleotiid ja selle kasutamine perifeerse neuronaalse lmmastikoksiidi sntaasi allareguleerimiseks ning farmatseutiline kompositsioon - Google Patents
Antisens-oligonukleotiid ja selle kasutamine perifeerse neuronaalse lmmastikoksiidi sntaasi allareguleerimiseks ning farmatseutiline kompositsioonInfo
- Publication number
- EE200600044A EE200600044A EEP200600044A EEP200600044A EE200600044A EE 200600044 A EE200600044 A EE 200600044A EE P200600044 A EEP200600044 A EE P200600044A EE P200600044 A EEP200600044 A EE P200600044A EE 200600044 A EE200600044 A EE 200600044A
- Authority
- EE
- Estonia
- Prior art keywords
- sase
- regulation
- pharmaceutical composition
- nitric oxide
- antisense oligonucleotide
- Prior art date
Links
- 108091034117 Oligonucleotide Proteins 0.000 title 1
- 239000000074 antisense oligonucleotide Substances 0.000 title 1
- 238000012230 antisense oligonucleotides Methods 0.000 title 1
- 230000003828 downregulation Effects 0.000 title 1
- 230000001537 neural effect Effects 0.000 title 1
- MWUXSHHQAYIFBG-UHFFFAOYSA-N nitrogen oxide Inorganic materials O=[N] MWUXSHHQAYIFBG-UHFFFAOYSA-N 0.000 title 1
- 230000002093 peripheral effect Effects 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/111—General methods applicable to biologically active non-coding nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2320/00—Applications; Uses
- C12N2320/30—Special therapeutic applications
- C12N2320/32—Special delivery means, e.g. tissue-specific
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Virology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EEP200600044A EE200600044A (et) | 2006-12-29 | 2006-12-29 | Antisens-oligonukleotiid ja selle kasutamine perifeerse neuronaalse lmmastikoksiidi sntaasi allareguleerimiseks ning farmatseutiline kompositsioon |
| PCT/EE2007/000026 WO2008080413A2 (en) | 2006-12-29 | 2007-12-21 | An antisense oligonucleotide, pharmaceutical composition and a method for downregulation of peripheral neuronal nitric oxide synthase and mu-opioid receptors and use of an antisense oligonucleotide for drug production |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EEP200600044A EE200600044A (et) | 2006-12-29 | 2006-12-29 | Antisens-oligonukleotiid ja selle kasutamine perifeerse neuronaalse lmmastikoksiidi sntaasi allareguleerimiseks ning farmatseutiline kompositsioon |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EE200600044A true EE200600044A (et) | 2008-12-15 |
Family
ID=39199385
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EEP200600044A EE200600044A (et) | 2006-12-29 | 2006-12-29 | Antisens-oligonukleotiid ja selle kasutamine perifeerse neuronaalse lmmastikoksiidi sntaasi allareguleerimiseks ning farmatseutiline kompositsioon |
Country Status (2)
| Country | Link |
|---|---|
| EE (1) | EE200600044A (et) |
| WO (1) | WO2008080413A2 (et) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001087285A2 (en) * | 2000-05-12 | 2001-11-22 | The Johns Hopkins University | Inhibition of the interaction of psd93 and psd95 with the nnos and nmda receptors |
| JP2008537739A (ja) * | 2005-03-21 | 2008-09-25 | ザ トラスティース オブ コロンビア ユニバーシティ イン ザ シティ オブ ニューヨーク | 新規神経疼痛経路 |
-
2006
- 2006-12-29 EE EEP200600044A patent/EE200600044A/et unknown
-
2007
- 2007-12-21 WO PCT/EE2007/000026 patent/WO2008080413A2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008080413A2 (en) | 2008-07-10 |
| WO2008080413A3 (en) | 2008-09-12 |
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