EE200200566A - Malonamic acids and their derivatives as thyroid receptor ligands - Google Patents

Malonamic acids and their derivatives as thyroid receptor ligands

Info

Publication number: EE200200566A
Authority: EE; Estonia
Prior art keywords: derivatives; receptor ligands; thyroid receptor; malonamic acids; malonamic
Prior art date: 2000-03-31

Application number

EEP200200566A

Other languages

Estonian (et)

Inventor

Erik Aspnes Gary

Phoebe Chiang Yuan-Ching

Gail Estep Kimberly

Original Assignee

Pfizer Products Inc.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-03-31

Filing date

2001-03-07

Publication date

2004-06-15

2001-03-07 Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.

2004-06-15 Publication of EE200200566A publication Critical patent/EE200200566A/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C235/16—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
- A61P5/16—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4 for decreasing, blocking or antagonising the activity of the thyroid hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/70—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/72—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms
- C07C235/80—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms having carbon atoms of carboxamide groups and keto groups bound to the same carbon atom, e.g. acetoacetamides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
- C07C311/29—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/16—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C317/22—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/46—Iso-indoles; Hydrogenated iso-indoles with an oxygen atom in position 1
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/18—Systems containing only non-condensed rings with a ring being at least seven-membered

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Hematology (AREA)
Obesity (AREA)
Physical Education & Sports Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Dermatology (AREA)
Rheumatology (AREA)
Ophthalmology & Optometry (AREA)
Neurology (AREA)
Emergency Medicine (AREA)
Biomedical Technology (AREA)
Urology & Nephrology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Child & Adolescent Psychology (AREA)
Psychiatry (AREA)
Vascular Medicine (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

EEP200200566A 2000-03-31 2001-03-07 Malonamic acids and their derivatives as thyroid receptor ligands EE200200566A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US19361800P	2000-03-31	2000-03-31
PCT/IB2001/000317 WO2001072692A1 (en)	2000-03-31	2001-03-07	Malonamic acids and derivatives thereof as thyroid receptor ligands

Publications (1)

Publication Number	Publication Date
EE200200566A true EE200200566A (en)	2004-06-15

Family

ID=22714346

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EEP200200566A EE200200566A (en)	2000-03-31	2001-03-07	Malonamic acids and their derivatives as thyroid receptor ligands

Country Status (38)

Country	Link
US (1)	US20070173548A1 (en)
EP (1)	EP1268404B1 (en)
JP (1)	JP3866977B2 (en)
KR (1)	KR20020089420A (en)
CN (1)	CN1422246A (en)
AP (1)	AP2002002634A0 (en)
AR (1)	AR033516A1 (en)
AT (1)	ATE382602T1 (en)
AU (1)	AU2001237665A1 (en)
BG (1)	BG107036A (en)
BR (1)	BR0109625A (en)
CA (1)	CA2403902C (en)
CR (1)	CR6742A (en)
CZ (1)	CZ20023190A3 (en)
DE (1)	DE60132181D1 (en)
DZ (1)	DZ3276A1 (en)
EA (1)	EA200200921A1 (en)
EE (1)	EE200200566A (en)
GT (1)	GT200100041A (en)
HK (1)	HK1052498A1 (en)
HU (1)	HUP0300329A3 (en)
IL (1)	IL151376A0 (en)
IS (1)	IS6516A (en)
MA (1)	MA26886A1 (en)
MX (1)	MXPA02009702A (en)
NO (1)	NO20024639D0 (en)
NZ (1)	NZ520660A (en)
OA (1)	OA12237A (en)
PA (1)	PA8513801A1 (en)
PE (1)	PE20011186A1 (en)
PL (1)	PL358596A1 (en)
SK (1)	SK13762002A3 (en)
SV (1)	SV2002000357A (en)
TN (1)	TNSN01048A1 (en)
TR (1)	TR200202249T2 (en)
WO (1)	WO2001072692A1 (en)
YU (1)	YU74102A (en)
ZA (1)	ZA200207444B (en)

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CA2741517A1 (en)	2008-10-27	2010-05-06	Cadila Healthcare Limited	Thyroid receptor ligands
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US8901114B2 (en)	2011-03-08	2014-12-02	Sanofi	Oxathiazine derivatives substituted with carbocycles or heterocycles, method for producing same, drugs containing said compounds, and use thereof
WO2012120053A1 (en)	2011-03-08	2012-09-13	Sanofi	Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
WO2012120056A1 (en)	2011-03-08	2012-09-13	Sanofi	Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof
EP2683703B1 (en)	2011-03-08	2015-05-27	Sanofi	Novel substituted phenyl-oxathiazine derivatives, method for producing them, drugs containing said compounds and the use thereof
EP2567959B1 (en)	2011-09-12	2014-04-16	Sanofi	6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
EP2695611B1 (en)	2012-08-06	2014-10-01	Dr. August Wolff GmbH & Co. KG Arzneimittel	Eprotirome for use in the prevention and/or treatment of hair disorders and compositions thereof
US10154988B2 (en)	2012-11-14	2018-12-18	The Johns Hopkins University	Methods and compositions for treating schizophrenia
US20170112741A1 (en) *	2014-04-09	2017-04-27	Goldcrest Medicine Institute Co., Ltd.	Agent for ameliorating skin symptom, hair growth agent or slimming agent
JP2020500199A (en)	2016-11-21	2020-01-09	バイキング・セラピューティクス・インコーポレイテッド	Methods of treating glycogen storage disease
AU2018280118B2 (en)	2017-06-05	2021-07-15	Viking Therapeutics, Inc.	Compositions for the treatment of fibrosis
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EA202091979A1 (en)	2018-03-22	2021-06-22	Вайкинг Терапьютикс, Инк.	CRYSTALLINE FORMS AND METHODS FOR OBTAINING CRYSTALLINE FORMS OF COMPOUNDS
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US6664291B2 (en) *	2000-03-31	2003-12-16	Pfizer, Inc.	Malonamic acids and derivatives thereof as thyroid receptor ligands

2001
- 2001-03-07 AU AU2001237665A patent/AU2001237665A1/en not_active Abandoned
- 2001-03-07 HU HU0300329A patent/HUP0300329A3/en unknown
- 2001-03-07 CN CN01807559A patent/CN1422246A/en active Pending
- 2001-03-07 CA CA002403902A patent/CA2403902C/en not_active Expired - Fee Related
- 2001-03-07 EE EEP200200566A patent/EE200200566A/en unknown
- 2001-03-07 DE DE60132181T patent/DE60132181D1/en not_active Expired - Lifetime
- 2001-03-07 IL IL15137601A patent/IL151376A0/en unknown
- 2001-03-07 EA EA200200921A patent/EA200200921A1/en unknown
- 2001-03-07 SK SK1376-2002A patent/SK13762002A3/en not_active Application Discontinuation
- 2001-03-07 MX MXPA02009702A patent/MXPA02009702A/en active IP Right Grant
- 2001-03-07 EP EP01910082A patent/EP1268404B1/en not_active Expired - Lifetime
- 2001-03-07 JP JP2001570607A patent/JP3866977B2/en not_active Expired - Fee Related
- 2001-03-07 NZ NZ520660A patent/NZ520660A/en not_active Application Discontinuation
- 2001-03-07 WO PCT/IB2001/000317 patent/WO2001072692A1/en not_active Ceased
- 2001-03-07 BR BR0109625-7A patent/BR0109625A/en not_active IP Right Cessation
- 2001-03-07 KR KR1020027013044A patent/KR20020089420A/en not_active Ceased
- 2001-03-07 TR TR2002/02249T patent/TR200202249T2/en unknown
- 2001-03-07 AT AT01910082T patent/ATE382602T1/en not_active IP Right Cessation
- 2001-03-07 PL PL01358596A patent/PL358596A1/en not_active Application Discontinuation
- 2001-03-07 OA OA1200200299A patent/OA12237A/en unknown
- 2001-03-07 CZ CZ20023190A patent/CZ20023190A3/en unknown
- 2001-03-07 AP APAP/P/2002/002634A patent/AP2002002634A0/en unknown
- 2001-03-07 YU YU74102A patent/YU74102A/en unknown
- 2001-03-07 DZ DZ013276A patent/DZ3276A1/en active
- 2001-03-07 HK HK03104860.6A patent/HK1052498A1/en unknown
- 2001-03-16 PA PA20018513801A patent/PA8513801A1/en unknown
- 2001-03-19 GT GT200100041A patent/GT200100041A/en unknown
- 2001-03-28 PE PE2001000290A patent/PE20011186A1/en not_active Application Discontinuation
- 2001-03-29 AR ARP010101509A patent/AR033516A1/en unknown
- 2001-03-30 TN TNTNSN01048A patent/TNSN01048A1/en unknown
- 2001-03-30 SV SV2001000357A patent/SV2002000357A/en not_active Application Discontinuation
2002
- 2002-08-21 IS IS6516A patent/IS6516A/en unknown
- 2002-08-26 BG BG107036A patent/BG107036A/en unknown
- 2002-08-28 CR CR6742A patent/CR6742A/en not_active Application Discontinuation
- 2002-09-17 ZA ZA200207444A patent/ZA200207444B/en unknown
- 2002-09-24 MA MA26837A patent/MA26886A1/en unknown
- 2002-09-27 NO NO20024639A patent/NO20024639D0/en not_active Application Discontinuation
2007
- 2007-03-07 US US11/715,035 patent/US20070173548A1/en not_active Abandoned

Also Published As

Publication number	Publication date
CZ20023190A3 (en)	2003-10-15
EP1268404B1 (en)	2008-01-02
DZ3276A1 (en)	2001-10-04
CR6742A (en)	2003-11-25
DE60132181D1 (en)	2008-02-14
AP2002002634A0 (en)	2002-09-30
CN1422246A (en)	2003-06-04
BR0109625A (en)	2003-04-22
NZ520660A (en)	2004-03-26
WO2001072692A1 (en)	2001-10-04
PL358596A1 (en)	2004-08-09
OA12237A (en)	2003-10-23
SK13762002A3 (en)	2004-01-08
PE20011186A1 (en)	2001-11-15
CA2403902C (en)	2007-04-24
NO20024639L (en)	2002-09-27
KR20020089420A (en)	2002-11-29
US20070173548A1 (en)	2007-07-26
JP2003528847A (en)	2003-09-30
EA200200921A1 (en)	2003-02-27
YU74102A (en)	2006-03-03
MA26886A1 (en)	2004-12-20
TR200202249T2 (en)	2003-01-21
HK1052498A1 (en)	2003-09-19
AU2001237665A1 (en)	2001-10-08
BG107036A (en)	2003-04-30
NO20024639D0 (en)	2002-09-27
PA8513801A1 (en)	2002-02-21
MXPA02009702A (en)	2003-03-27
JP3866977B2 (en)	2007-01-10
AR033516A1 (en)	2003-12-26
IS6516A (en)	2002-08-21
ATE382602T1 (en)	2008-01-15
HUP0300329A3 (en)	2004-08-30
EP1268404A1 (en)	2003-01-02
ZA200207444B (en)	2003-09-17
IL151376A0 (en)	2003-04-10
HUP0300329A2 (en)	2003-07-28
GT200100041A (en)	2002-03-22
CA2403902A1 (en)	2001-10-04
TNSN01048A1 (en)	2005-11-10
SV2002000357A (en)	2002-07-16

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