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EE200200260A - Pürasolo[1,5-d][1,2,4]triasiinderivaat, selle saamine ja kasutamine ravimi valmistamiseks, mis on ette nähtud kognitsiooni suurendamiseks, ning seda sisaldav farmatseutiline kompositsioon - Google Patents

Pürasolo[1,5-d][1,2,4]triasiinderivaat, selle saamine ja kasutamine ravimi valmistamiseks, mis on ette nähtud kognitsiooni suurendamiseks, ning seda sisaldav farmatseutiline kompositsioon

Info

Publication number
EE200200260A
EE200200260A EEP200200260A EEP200200260A EE200200260A EE 200200260 A EE200200260 A EE 200200260A EE P200200260 A EEP200200260 A EE P200200260A EE P200200260 A EEP200200260 A EE P200200260A EE 200200260 A EE200200260 A EE 200200260A
Authority
EE
Estonia
Prior art keywords
preparation
pyrazolo
cognition
medicament
enhancement
Prior art date
Application number
EEP200200260A
Other languages
English (en)
Inventor
Robert Carling William
Jane Bryant Helen
Stuart Chambers Mark
Christine Hobbs Sarah
Jones Philip
Murray Macleod Angus
Original Assignee
Merck Sharp & Dohme Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9927874.9A external-priority patent/GB9927874D0/en
Priority claimed from GB0009602A external-priority patent/GB0009602D0/en
Priority claimed from GB0018651A external-priority patent/GB0018651D0/en
Application filed by Merck Sharp & Dohme Limited filed Critical Merck Sharp & Dohme Limited
Publication of EE200200260A publication Critical patent/EE200200260A/et

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Psychiatry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
EEP200200260A 1999-11-25 2000-11-22 Pürasolo[1,5-d][1,2,4]triasiinderivaat, selle saamine ja kasutamine ravimi valmistamiseks, mis on ette nähtud kognitsiooni suurendamiseks, ning seda sisaldav farmatseutiline kompositsioon EE200200260A (et)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9927874.9A GB9927874D0 (en) 1999-11-25 1999-11-25 Therapeutic agents
GB0009602A GB0009602D0 (en) 2000-04-18 2000-04-18 Therapeutic agents
GB0018651A GB0018651D0 (en) 2000-07-28 2000-07-28 Therapeutic agents
PCT/GB2000/004450 WO2001038331A2 (en) 1999-11-25 2000-11-22 Pyrazolo[1,5-d][1,2,4]triazines for enhancing cognition

Publications (1)

Publication Number Publication Date
EE200200260A true EE200200260A (et) 2003-06-16

Family

ID=27255677

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200200260A EE200200260A (et) 1999-11-25 2000-11-22 Pürasolo[1,5-d][1,2,4]triasiinderivaat, selle saamine ja kasutamine ravimi valmistamiseks, mis on ette nähtud kognitsiooni suurendamiseks, ning seda sisaldav farmatseutiline kompositsioon

Country Status (20)

Country Link
US (1) US6355638B1 (et)
EP (1) EP1235829A2 (et)
JP (1) JP2003514909A (et)
KR (1) KR20020053091A (et)
CN (1) CN1391574A (et)
AU (1) AU1533001A (et)
BG (1) BG106734A (et)
BR (1) BR0015126A (et)
CA (1) CA2391103A1 (et)
CZ (1) CZ20021813A3 (et)
EA (1) EA200200599A1 (et)
EE (1) EE200200260A (et)
HK (1) HK1046406A1 (et)
HU (1) HUP0203579A3 (et)
IL (1) IL149051A0 (et)
MX (1) MXPA02005233A (et)
NO (1) NO20022456L (et)
PL (1) PL355637A1 (et)
SK (1) SK8952002A3 (et)
WO (1) WO2001038331A2 (et)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0128499D0 (en) * 2001-11-28 2002-01-23 Merck Sharp & Dohme Therapeutic agents
EP2298296A1 (en) * 2009-08-25 2011-03-23 CNRS Centre National De La Recherche Scientifique Composition and method for treating cognitive impairments in down syndrome subjects
WO2011150156A2 (en) * 2010-05-26 2011-12-01 Sunovion Pharmaceuticals Inc. Heteroaryl compounds and methods of use thereof
US20150374705A1 (en) 2012-02-14 2015-12-31 Shanghai Institues for Biological Sciences Substances for treatment or relief of pain
CN107344936B (zh) * 2016-05-06 2022-06-03 上海赛默罗生物科技有限公司 三唑哒嗪类衍生物、其制备方法、药物组合物和用途
CN107344938B (zh) * 2016-05-06 2022-05-06 上海赛默罗生物科技有限公司 吡唑-三嗪类衍生物、其制备方法、药物组合物和用途
TW202115013A (zh) * 2019-06-19 2021-04-16 美商拜奧馬林製藥公司 用於治療疾病之乙醇酸氧化酶(glycolate oxidase)抑制劑

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0915875B1 (en) * 1996-07-25 2003-04-09 MERCK SHARP & DOHME LTD. Substituted triazolo-pyridazine derivatives as ligands for gaba receptors
GB9715977D0 (en) * 1997-07-29 1997-10-01 Merck Sharp & Dohme Therapeutic agents
US6303597B1 (en) * 1998-01-14 2001-10-16 Merck Sharp & Dohme Limited Triazolo-pyridazine derivatives as ligands for GABA receptors
GB9806102D0 (en) * 1998-03-20 1998-05-20 Merck Sharp & Dohme Therapeutic agents
US6479506B1 (en) * 1998-06-16 2002-11-12 Merck Sharp & Dohme Ltd. Triazolo-pyridine derivatives as ligands for GABA receptors
JP2002527519A (ja) * 1998-10-16 2002-08-27 メルク シャープ エンド ドーム リミテッド Ｇａｂａ受容体のリガンドとしてのピラゾロトリアジン誘導体

Also Published As

Publication number Publication date
CZ20021813A3 (cs) 2002-08-14
US6355638B1 (en) 2002-03-12
AU1533001A (en) 2001-06-04
KR20020053091A (ko) 2002-07-04
EA200200599A1 (ru) 2002-12-26
HK1046406A1 (zh) 2003-01-10
NO20022456D0 (no) 2002-05-24
WO2001038331A2 (en) 2001-05-31
BG106734A (en) 2003-02-28
HUP0203579A2 (hu) 2003-03-28
JP2003514909A (ja) 2003-04-22
NO20022456L (no) 2002-05-24
CN1391574A (zh) 2003-01-15
IL149051A0 (en) 2002-11-10
EP1235829A2 (en) 2002-09-04
SK8952002A3 (en) 2002-10-08
CA2391103A1 (en) 2001-05-31
HUP0203579A3 (en) 2003-07-28
MXPA02005233A (es) 2002-11-07
BR0015126A (pt) 2002-07-02
WO2001038331A3 (en) 2001-11-08
PL355637A1 (en) 2004-05-04

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