EE200200191A - Monoamiini taasomastamise inhibiitoritena kasulikud biarüüleetri derivaadid - Google Patents
Monoamiini taasomastamise inhibiitoritena kasulikud biarüüleetri derivaadidInfo
- Publication number
- EE200200191A EE200200191A EEP200200191A EEP200200191A EE200200191A EE 200200191 A EE200200191 A EE 200200191A EE P200200191 A EEP200200191 A EE P200200191A EE P200200191 A EEP200200191 A EE P200200191A EE 200200191 A EE200200191 A EE 200200191A
- Authority
- EE
- Estonia
- Prior art keywords
- reuptake inhibitors
- ether derivatives
- derivatives useful
- monoamine reuptake
- biaryl ether
- Prior art date
Links
- -1 Biaryl ether derivatives Chemical class 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 230000000407 monoamine reuptake Effects 0.000 title 1
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- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
- C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
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- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
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- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
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- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15927699P | 1999-10-13 | 1999-10-13 | |
| US16776199P | 1999-11-29 | 1999-11-29 | |
| PCT/IB2000/001373 WO2001027068A1 (en) | 1999-10-13 | 2000-09-27 | Biaryl ether derivatives useful as monoamine reuptake inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EE200200191A true EE200200191A (et) | 2003-06-16 |
Family
ID=26855804
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EEP200200191A EE200200191A (et) | 1999-10-13 | 2000-09-27 | Monoamiini taasomastamise inhibiitoritena kasulikud biarüüleetri derivaadid |
Country Status (43)
Families Citing this family (71)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US6448293B1 (en) | 2000-03-31 | 2002-09-10 | Pfizer Inc. | Diphenyl ether compounds useful in therapy |
| US6610747B2 (en) | 2000-08-31 | 2003-08-26 | Pfizer Inc. | Phenoxybenzylamine derivatives as SSRIs |
| US6630504B2 (en) | 2000-08-31 | 2003-10-07 | Pfizer Inc. | Phenoxyphenylheterocyclyl derivatives as SSRIs |
| US6436938B1 (en) * | 2001-01-22 | 2002-08-20 | Pfizer Inc. | Combination treatment for depression |
| US20030207857A1 (en) | 2001-04-11 | 2003-11-06 | Adam Mavis D. | Phenyl heterocyclyl ethers |
| GB0109103D0 (en) * | 2001-04-11 | 2001-05-30 | Pfizer Ltd | Novel compounds |
| US20020165217A1 (en) * | 2001-05-01 | 2002-11-07 | Pfizer Inc. | Combination treatment for anxiety and depression |
| EP1262196A3 (en) * | 2001-05-23 | 2002-12-18 | Pfizer Products Inc. | Combination of a monoamine reuptake inhibitor and an opioid antagonist for use in alcoholism and alcohol dependence |
| US20020183306A1 (en) * | 2001-05-30 | 2002-12-05 | Pfizer Inc. | Combination treatment for sleep disorders including sleep apnea |
| KR20040066895A (ko) * | 2001-12-11 | 2004-07-27 | 일라이 릴리 앤드 캄파니 | 인지 감퇴 치료를 위한, 노르에피네프린 재흡수 억제제의용도 |
| US7105526B2 (en) | 2002-06-28 | 2006-09-12 | Banyu Pharmaceuticals Co., Ltd. | Benzimidazole derivatives |
| KR20070091049A (ko) | 2002-12-13 | 2007-09-06 | 워너-램버트 캄파니 엘엘씨 | 하부요로증상을 치료하기 위한 알파-2-델타 리간드 |
| US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| AU2004226838B8 (en) * | 2003-04-04 | 2009-06-11 | H. Lundbeck A/S | 4-(2-phenylsulfanyl-phenyl)-piperidine derivatives as serotonin reuptake inhibitors |
| CL2004000725A1 (es) * | 2003-04-04 | 2005-02-18 | Lundbeck & Co As H | Compuestos derivados de 4-(2-fenilsulfanilfenil)piperidina; composicion farmaceutica; y uso del compuesto para el tratamiento de trastornos afectivos como la depresion, trastornos de ansiedad, trastorno obsesivo compulsivo, trastorno de panico, ataqu |
| DK1635828T3 (da) * | 2003-04-04 | 2008-08-11 | Lundbeck & Co As H | 4-(2-phenyloxyphenyl)-piperidin- eller -1,2,3,6-tetrahydropyridinderivater som serotoningenoptagelseshæmmere |
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| AR054393A1 (es) | 2005-06-17 | 2007-06-20 | Lundbeck & Co As H | Derivados de benzo(b)furano y benzo(b)tiofeno, composiciones farmaceuticas que los contienen y su uso en la fabricacion de un medicamento para el tratamiento de enfermedades mediadas por la inhibicion de la reabsorcion de neurotransmisores de amina biogenicos. |
| US20100216758A1 (en) | 2005-08-10 | 2010-08-26 | Makoto Ando | Pyridone Compounds |
| WO2007024004A1 (ja) | 2005-08-24 | 2007-03-01 | Banyu Pharmaceutical Co., Ltd. | フェニルピリドン誘導体 |
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| US20080255084A1 (en) | 2005-10-21 | 2008-10-16 | Randy Lee Webb | Combination of Organic Compounds |
| CA2627139A1 (en) | 2005-10-27 | 2007-05-03 | Banyu Pharmaceutical Co., Ltd. | Novel benzoxathiin derivative |
| BRPI0618354B8 (pt) | 2005-11-10 | 2021-05-25 | Banyu Pharma Co Ltd | composto e seu uso, composição farmacêutica, preventivo ou remédio |
| CN101511785A (zh) * | 2006-06-29 | 2009-08-19 | 詹森药业有限公司 | 取代的苄基胺化合物 |
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| WO2008047544A1 (en) | 2006-09-28 | 2008-04-24 | Banyu Pharmaceutical Co., Ltd. | Diaryl ketimine derivative |
| EA017171B1 (ru) | 2006-12-22 | 2012-10-30 | Рекордати Айерленд Лимитед | КОМБИНИРОВАННАЯ ТЕРАПИЯ ЗАБОЛЕВАНИЙ НИЖНИХ МОЧЕВЫВОДЯЩИХ ПУТЕЙ С ИСПОЛЬЗОВАНИЕМ ЛИГАНДОВ αδ И НЕСТЕРОИДНЫХ ПРОТИВОВОСПАЛИТЕЛЬНЫХ ПРЕПАРАТОВ (НПВП) |
| CN100413782C (zh) * | 2007-02-13 | 2008-08-27 | 袁茂豪 | 一种高纯超细球形硅微粉的制备方法 |
| WO2008120653A1 (ja) | 2007-04-02 | 2008-10-09 | Banyu Pharmaceutical Co., Ltd. | インドールジオン誘導体 |
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| MX2009013332A (es) | 2007-06-08 | 2010-01-25 | Mannkind Corp | Inhibidores de ire-1 alfa. |
| US20110015181A1 (en) | 2008-03-06 | 2011-01-20 | Makoto Ando | Alkylaminopyridine derivative |
| EP2272841A1 (en) | 2008-03-28 | 2011-01-12 | Banyu Pharmaceutical Co., Ltd. | Diarylmethylamide derivative having antagonistic activity on melanin-concentrating hormone receptor |
| CA2726917C (en) | 2008-06-04 | 2018-06-26 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| AU2009261248A1 (en) | 2008-06-19 | 2009-12-23 | Banyu Pharmaceutical Co., Ltd. | Spirodiamine-diarylketoxime derivative |
| EP3241839B1 (en) | 2008-07-16 | 2019-09-04 | Bausch Health Ireland Limited | Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders |
| US20110124674A1 (en) | 2008-07-30 | 2011-05-26 | Hiroyuki Kishino | 5/5-or 5/6-membered condensed ring cycloalkylamine derivative |
| US8410284B2 (en) | 2008-10-22 | 2013-04-02 | Merck Sharp & Dohme Corp | Cyclic benzimidazole derivatives useful as anti-diabetic agents |
| CA2741672A1 (en) | 2008-10-31 | 2010-05-06 | Merck Sharp & Dohme Corp. | Novel cyclic benzimidazole derivatives useful anti-diabetic agents |
| EP2379562A1 (en) | 2008-12-16 | 2011-10-26 | Schering Corporation | Bicyclic pyranone derivatives as nicotinic acid receptor agonists |
| US20110245209A1 (en) | 2008-12-16 | 2011-10-06 | Schering Corporation | Pyridopyrimidine derivatives and methods of use thereof |
| US8895596B2 (en) | 2010-02-25 | 2014-11-25 | Merck Sharp & Dohme Corp | Cyclic benzimidazole derivatives useful as anti-diabetic agents |
| EP2590951B1 (en) | 2010-07-09 | 2015-01-07 | Pfizer Limited | Benzenesulfonamides useful as sodium channel inhibitors |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| EA201690035A1 (ru) | 2011-02-25 | 2016-05-31 | Мерк Шарп Энд Домэ Корп. | Новые циклические производные азабензимидазола, используемые в качестве антидиабетических агентов |
| EP2875029B8 (en) | 2012-07-18 | 2021-12-15 | University of Notre Dame du Lac | 5,5-heteroaromatic anti-infective compounds |
| JP2015525782A (ja) | 2012-08-02 | 2015-09-07 | メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. | 抗糖尿病性三環式化合物 |
| WO2014130608A1 (en) | 2013-02-22 | 2014-08-28 | Merck Sharp & Dohme Corp. | Antidiabetic bicyclic compounds |
| WO2014139388A1 (en) | 2013-03-14 | 2014-09-18 | Merck Sharp & Dohme Corp. | Novel indole derivatives useful as anti-diabetic agents |
| EP2968439A2 (en) | 2013-03-15 | 2016-01-20 | Synergy Pharmaceuticals Inc. | Compositions useful for the treatment of gastrointestinal disorders |
| CA2905438A1 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
| EA201592263A1 (ru) | 2013-06-05 | 2016-05-31 | Синерджи Фармасьютикалз, Инк. | Ультрачистые агонисты гуанилатциклазы c, способ их получения и использования |
| CN104341336B (zh) * | 2013-08-02 | 2018-10-16 | 上海科胜药物研发有限公司 | 一种合成阿哌沙班重要中间体的新方法 |
| WO2015051496A1 (en) | 2013-10-08 | 2015-04-16 | Merck Sharp & Dohme Corp. | Antidiabetic tricyclic compounds |
| KR102431436B1 (ko) | 2014-08-29 | 2022-08-10 | 테스 파마 에스.알.엘. | α-아미노-β-카복시뮤콘산 세미알데히드 데카복실라제의 억제제 |
| US20180134667A1 (en) | 2016-10-14 | 2018-05-17 | TES Pharma S.r.I. | Inhibitors of alpha-amino-beta-carboxymuconic acid semialdehyde decarboxylase |
| WO2018106518A1 (en) | 2016-12-06 | 2018-06-14 | Merck Sharp & Dohme Corp. | Antidiabetic heterocyclic compounds |
| WO2018118670A1 (en) | 2016-12-20 | 2018-06-28 | Merck Sharp & Dohme Corp. | Antidiabetic spirochroman compounds |
| WO2020104456A1 (en) | 2018-11-20 | 2020-05-28 | Tes Pharma S.R.L | INHIBITORS OF α-AMINO-β-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA923283B (en) * | 1991-05-29 | 1993-01-27 | Akzo Nv | Phenoxyphenyl derivatives |
| DE4303676A1 (de) * | 1993-02-09 | 1994-08-11 | Bayer Ag | 1-Aryltriazolin(thi)one |
| CZ293595A3 (cs) * | 1995-11-09 | 1999-12-15 | Farmak A. S. | Deriváty N,N-dimethyl-2-(arylthio)benzylaminu, jejich soli, způsoby jejich přípravy a jejich použití v léčivých přípravcích |
| DE19853864A1 (de) * | 1998-07-09 | 2000-01-13 | Bayer Ag | Substituierte Phenyluracile |
| DE19838706A1 (de) * | 1998-08-26 | 2000-03-02 | Bayer Ag | Substituierte 3-Aryl-pyrazole |
| DE19901846A1 (de) * | 1999-01-19 | 2000-07-20 | Bayer Ag | Substituierte Arylheterocyclen |
-
2000
- 2000-09-27 NZ NZ517696A patent/NZ517696A/xx unknown
- 2000-09-27 HK HK02109177.4A patent/HK1047577B/zh not_active IP Right Cessation
- 2000-09-27 WO PCT/IB2000/001373 patent/WO2001027068A1/en not_active Ceased
- 2000-09-27 IL IL14910500A patent/IL149105A0/xx unknown
- 2000-09-27 HR HR20020324A patent/HRP20020324A2/hr not_active Application Discontinuation
- 2000-09-27 TR TR2002/01004T patent/TR200201004T2/xx unknown
- 2000-09-27 EP EP00960916A patent/EP1220831B1/en not_active Expired - Lifetime
- 2000-09-27 HU HU0203448A patent/HUP0203448A3/hu unknown
- 2000-09-27 DZ DZ003192A patent/DZ3192A1/xx active
- 2000-09-27 CZ CZ20021180A patent/CZ20021180A3/cs unknown
- 2000-09-27 AT AT00960916T patent/ATE297374T1/de not_active IP Right Cessation
- 2000-09-27 MX MXPA02003793A patent/MXPA02003793A/es active IP Right Grant
- 2000-09-27 BR BR0014733-8A patent/BR0014733A/pt not_active Application Discontinuation
- 2000-09-27 CA CA002387517A patent/CA2387517C/en not_active Expired - Fee Related
- 2000-09-27 EA EA200200291A patent/EA005671B1/ru not_active IP Right Cessation
- 2000-09-27 YU YU21602A patent/YU21602A/sh unknown
- 2000-09-27 GE GEAP20006411A patent/GEP20043160B/en unknown
- 2000-09-27 ES ES00960916T patent/ES2240155T3/es not_active Expired - Lifetime
- 2000-09-27 KR KR10-2002-7004767A patent/KR100524159B1/ko not_active Expired - Fee Related
- 2000-09-27 JP JP2001530089A patent/JP2003511434A/ja active Pending
- 2000-09-27 DE DE60020726T patent/DE60020726T2/de not_active Expired - Fee Related
- 2000-09-27 EE EEP200200191A patent/EE200200191A/xx unknown
- 2000-09-27 AU AU73070/00A patent/AU769430B2/en not_active Ceased
- 2000-09-27 CN CNB008141592A patent/CN1203047C/zh not_active Expired - Fee Related
- 2000-09-27 DK DK00960916T patent/DK1220831T3/da active
- 2000-09-27 AP APAP/P/2002/002481A patent/AP2002002481A0/en unknown
- 2000-09-27 SK SK473-2002A patent/SK4732002A3/sk unknown
- 2000-09-27 PT PT00960916T patent/PT1220831E/pt unknown
- 2000-09-27 PL PL00355289A patent/PL355289A1/xx not_active Application Discontinuation
- 2000-09-27 OA OA1200200106A patent/OA12062A/en unknown
- 2000-10-06 TW TW094111255A patent/TW200526549A/zh unknown
- 2000-10-10 GT GT200000167A patent/GT200000167A/es unknown
- 2000-10-11 PE PE2000001092A patent/PE20010683A1/es not_active Application Discontinuation
- 2000-10-11 PA PA20008504801A patent/PA8504801A1/es unknown
- 2000-10-12 CO CO00077988A patent/CO5261551A1/es not_active Application Discontinuation
- 2000-10-12 AR ARP000105371A patent/AR030533A1/es unknown
- 2000-10-12 TN TNTNSN00200A patent/TNSN00200A1/fr unknown
- 2000-10-12 SV SV2000000197A patent/SV2002000197A/es unknown
-
2002
- 2002-03-19 IS IS6313A patent/IS6313A/is unknown
- 2002-04-08 MA MA26589A patent/MA26827A1/fr unknown
- 2002-04-08 CR CR6616A patent/CR6616A/es not_active Application Discontinuation
- 2002-04-08 NO NO20021659A patent/NO20021659L/no unknown
- 2002-04-10 BG BG106603A patent/BG106603A/bg unknown
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