[go: up one dir, main page]

EE04235B1 - Combination of active substances, namely tetrahydropyridines and acetylcholinesterase inhibitors, for the treatment of senile dementia of the Alzheimer's disease type - Google Patents

Combination of active substances, namely tetrahydropyridines and acetylcholinesterase inhibitors, for the treatment of senile dementia of the Alzheimer's disease type

Info

Publication number
EE04235B1
EE04235B1 EEP200000290A EEP200000290A EE04235B1 EE 04235 B1 EE04235 B1 EE 04235B1 EE P200000290 A EEP200000290 A EE P200000290A EE P200000290 A EEP200000290 A EE P200000290A EE 04235 B1 EE04235 B1 EE 04235B1
Authority
EE
Estonia
Prior art keywords
tetrahydropyridines
alzheimer
namely
treatment
combination
Prior art date
Application number
EEP200000290A
Other languages
Estonian (et)
Inventor
Maffrand Jean-Pierre
Soubrie Philippe
Terranova Jean-Paul
Original Assignee
Sanofi-Synthlabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9714322A external-priority patent/FR2771007B1/en
Priority claimed from FR9714324A external-priority patent/FR2771006B1/en
Application filed by Sanofi-Synthlabo filed Critical Sanofi-Synthlabo
Publication of EE200000290A publication Critical patent/EE200000290A/en
Publication of EE04235B1 publication Critical patent/EE04235B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
EEP200000290A 1997-11-14 1998-11-09 Combination of active substances, namely tetrahydropyridines and acetylcholinesterase inhibitors, for the treatment of senile dementia of the Alzheimer's disease type EE04235B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9714322A FR2771007B1 (en) 1997-11-14 1997-11-14 COMBINATION OF ACTIVE INGREDIENTS FOR THE TREATMENT OF SENILE DEMENTIA OF THE ALZHEIMER TYPE
FR9714324A FR2771006B1 (en) 1997-11-14 1997-11-14 COMBINATION OF ACTIVE INGREDIENTS FOR THE TREATMENT OF SENILE DEMENTIA OF THE ALZHEIMER TYPE
PCT/FR1998/002384 WO1999025363A1 (en) 1997-11-14 1998-11-09 Combination of active principles, in particular of tetrahydropyridins and acetylcholinesterase inhibiting agents, for treating senile dementia such as alzheimer dementia

Publications (2)

Publication Number Publication Date
EE200000290A EE200000290A (en) 2001-06-15
EE04235B1 true EE04235B1 (en) 2004-02-16

Family

ID=26233932

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200000290A EE04235B1 (en) 1997-11-14 1998-11-09 Combination of active substances, namely tetrahydropyridines and acetylcholinesterase inhibitors, for the treatment of senile dementia of the Alzheimer's disease type

Country Status (27)

Country Link
EP (1) EP1030671A1 (en)
JP (1) JP2001523642A (en)
KR (1) KR100599350B1 (en)
CN (1) CN1243540C (en)
AU (1) AU743228B2 (en)
BG (1) BG64819B1 (en)
BR (1) BR9814035A (en)
CA (1) CA2309966A1 (en)
CO (1) CO4980891A1 (en)
DZ (1) DZ2649A1 (en)
EA (1) EA003255B1 (en)
EE (1) EE04235B1 (en)
HU (1) HUP0100098A3 (en)
ID (1) ID24933A (en)
IL (2) IL136122A0 (en)
IS (1) IS5482A (en)
MY (1) MY120461A (en)
NO (1) NO20002450L (en)
NZ (1) NZ504420A (en)
OA (1) OA11464A (en)
PL (1) PL194597B1 (en)
SA (1) SA98190747B1 (en)
SK (1) SK286040B6 (en)
TR (1) TR200001262T2 (en)
TW (1) TW585766B (en)
UY (1) UY25247A1 (en)
WO (1) WO1999025363A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE42327E1 (en) * 2002-06-14 2011-05-03 Toyama Chemical Co., Ltd. Medicinal compositions improving brain function and method for improving brain function
AU2003266967B2 (en) * 2002-08-07 2006-11-16 Novartis Ag Methods for the treatment of dementia based on Apo E genotype
CN1520818A (en) * 2003-02-09 2004-08-18 山东绿叶天然药物研究开发有限公司 Cholinesterase inhibitor pharmaceutical composition for senile dementia
EP1830886B1 (en) 2004-12-27 2016-04-13 Eisai R&D Management Co., Ltd. Method for stabilizing anti-dementia drug
DK3099296T3 (en) 2014-01-31 2019-04-15 Cognition Therapeutics Inc ISO-INDOLINE DERIVATIVES, COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASE
KR102614814B1 (en) 2017-05-15 2023-12-20 카그니션 테라퓨틱스, 인코퍼레이티드 Composition for treating neurodegenerative diseases
KR102224918B1 (en) 2018-03-20 2021-03-09 (주)인벤티지랩 Pharmaceutiical composition comprising memantine and donepezil for preventing or treating cognitive impairment-related disease and preparation method thereof
WO2019182319A1 (en) * 2018-03-20 2019-09-26 (주)인벤티지랩 Method for preparing pharmaceutical composition for preventing or treating cognitive disorder-associated diseases, and pharmaceutical composition for preventing or treating cognitive disorder-associated diseases, prepared by preparation method
CN109265391B (en) * 2018-11-13 2021-11-19 枣庄学院 Biphenyl polysubstituted 1,2,5, 6-tetrahydropyridine compound and synthetic method and application thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2662355B1 (en) * 1990-05-22 1994-11-10 Sanofi Sa USE OF 1- [2- (2-NAPHTYL) ETHYL] -4- (3-TRIFLUOROMETHYLPHENYL) -1,2,3,6-TETRAHYDROPYRIDINE FOR THE PREPARATION OF MEDICINES FOR THE TREATMENT OF BRAIN AND NEURAL DISORDERS.
US5453428A (en) * 1991-02-14 1995-09-26 The Mount Sinai School Of Medicine Of The City Of New York Method and composition for the treatment of apathy-amotivation syndrome
CA2213000A1 (en) * 1995-03-06 1996-09-12 Interneuron Pharmaceuticals, Inc. Reduction of infarct volume using citicoline
FR2736053B1 (en) * 1995-06-28 1997-09-19 Sanofi Sa NEWS 1-PHENYLALKYL-1,2,3,6-TETRAHYDROPYRIDINES

Also Published As

Publication number Publication date
IS5482A (en) 2000-05-09
CN1243540C (en) 2006-03-01
IL136122A (en) 2006-07-05
UY25247A1 (en) 2001-05-31
SA98190747B1 (en) 2006-11-04
ID24933A (en) 2000-08-31
CO4980891A1 (en) 2000-11-27
AU1160999A (en) 1999-06-07
SK7112000A3 (en) 2000-10-09
EA003255B1 (en) 2003-02-27
CA2309966A1 (en) 1999-05-27
BG64819B1 (en) 2006-05-31
NO20002450D0 (en) 2000-05-11
MY120461A (en) 2005-10-31
NZ504420A (en) 2003-08-29
HUP0100098A2 (en) 2001-07-30
IL136122A0 (en) 2001-05-20
EA200000412A1 (en) 2000-12-25
HUP0100098A3 (en) 2001-12-28
EE200000290A (en) 2001-06-15
EP1030671A1 (en) 2000-08-30
KR20010032099A (en) 2001-04-16
PL194597B1 (en) 2007-06-29
TR200001262T2 (en) 2001-01-22
AU743228B2 (en) 2002-01-24
TW585766B (en) 2004-05-01
NO20002450L (en) 2000-07-14
WO1999025363A1 (en) 1999-05-27
CN1285742A (en) 2001-02-28
BR9814035A (en) 2000-09-26
BG104428A (en) 2001-08-31
OA11464A (en) 2003-11-18
PL340500A1 (en) 2001-02-12
JP2001523642A (en) 2001-11-27
KR100599350B1 (en) 2006-07-12
DZ2649A1 (en) 2004-12-28
SK286040B6 (en) 2008-01-07

Similar Documents

Publication Publication Date Title
ATE253361T1 (en) AGENTS FOR THE CONTROLLED RELEASE OF PAROXETINE
DE60023128D1 (en) PYRAZOLECARBOXAMIDE FOR THE TREATMENT OF FATIBILITY AND OTHER DISEASES
DE60022867D1 (en) 1-Arenesulfonyl-2-aryl-pyrrolidine and piperidine Derivatives for the treatment of CNS disorders
AU5716898A (en) Acetylcholinesterase inhibitors in combination with muscarinic agonists for the treatment of alzheimer's disease
DE69806801D1 (en) GALENIC PREPARATION FOR THE PREVENTION AND TREATMENT OF HEPATOCARCINOMA
NO990433D0 (en) New compounds and compositions for the treatment of diseases associated with tryptase activity
NO973178D0 (en) Indole derivatives useful in the treatment of cheese porosis
AU1509999A (en) Herbal drug composition for the prevention and treatment of dementia
NO20001869L (en) Procedure for the treatment of Alzheimer's disease
HUP9900927A3 (en) Substituted 4-(1h-benzimidazol-2-yl-amino)piperidines useful for the treatment of allergic diseases
EE04235B1 (en) Combination of active substances, namely tetrahydropyridines and acetylcholinesterase inhibitors, for the treatment of senile dementia of the Alzheimer's disease type
AU3364499A (en) Method for delaying the onset of alzheimer's disease and for treating or delaying the onset of other amyloidosis-related diseases/disorders
DE69420229D1 (en) Pharmaceutical composition for the treatment of AIDS
ATE234617T1 (en) USE OF THE SAREDUTANT AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS FOR THE TREATMENT OF SEVERE DEPRESSION
NO991800L (en) Process for the preparation of 2-azadihydroxybicyclo [2.2.2] -heptane compounds and L-tartaric acid salts of the compounds
PT888114E (en) USING (+) - ALPHA- (2,3-DIMETOXYPHENYL) -1- [2- (4-FLUOROPHENYL) ETHYL] -4-PIPERIDINOMETHANOL IN THE TREATMENT OF DEPRESSIVE DISEASES AND BIPOLAR DISEASES
ATE346840T1 (en) AMINOALKYLPHENOL DERIVATIVES FOR THE TREATMENT OF DEPRESSION AND MEMORY DISORDER
GR3033316T3 (en) Substituted 4-(6-fluoro-[1H]-indol-3-yl)-1,2,3,6-tetrahydropyridine for the treatment of CNS-disorders
NO981499L (en) Process for the preparation of titanium dioxide
NO20014026D0 (en) Antispasmodic derivatives for the treatment of significant tremor
KR100248098B1 (en) Pharmaceutical composition for the treatment of dementia
HUP0202145A3 (en) The use of r(+)-alpha-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol for the treatment of sleep disorders
ZA989955B (en) Combination of active ingredients for the treatment of senile dementia of the alzheimer type
ZA974390B (en) Carboxamide derivatives of pyrrolidine piperidine and hexahydroazepine for the treatment of thrombosis disorders.
HUP9902445A3 (en) Carboxamide derivatives of pyrrolidine, piperidine and hexahydroazepine and pharmaceutical compositions containing them for the treatment of thrombosis disorders

Legal Events

Date Code Title Description
HD1A Correction of address
HC1A Change of owner name
KB4A Valid patent at the end of a year

Effective date: 20041231

KB4A Valid patent at the end of a year

Effective date: 20051231

KB4A Valid patent at the end of a year

Effective date: 20061231

KB4A Valid patent at the end of a year

Effective date: 20071231

KB4A Valid patent at the end of a year

Effective date: 20081231

MM4A Lapsed by not paying the annual fees

Effective date: 20081109