EE03395B1 - Bensotiasolooni derivaadid, protsessid ja kasutatud vaheühendid nende saamiseks ning neid sisaldavad ravimkoostised - Google Patents
Bensotiasolooni derivaadid, protsessid ja kasutatud vaheühendid nende saamiseks ning neid sisaldavad ravimkoostisedInfo
- Publication number
- EE03395B1 EE03395B1 EE9800069A EE9800069A EE03395B1 EE 03395 B1 EE03395 B1 EE 03395B1 EE 9800069 A EE9800069 A EE 9800069A EE 9800069 A EE9800069 A EE 9800069A EE 03395 B1 EE03395 B1 EE 03395B1
- Authority
- EE
- Estonia
- Prior art keywords
- processes
- preparation
- pharmaceutical compositions
- compositions containing
- intermediates used
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
- C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C311/03—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the sulfonamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C311/04—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the sulfonamide groups bound to hydrogen atoms or to acyclic carbon atoms to acyclic carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
- C07C311/23—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atoms of the sulfonamide groups bound to acyclic carbon atoms
- C07C311/24—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atoms of the sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/10—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C323/11—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/12—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/16—Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9518952.8A GB9518952D0 (en) | 1995-09-15 | 1995-09-15 | Compounds |
| GBGB9614346.6A GB9614346D0 (en) | 1996-07-10 | 1996-07-10 | Benzothiazolone derivatives |
| PCT/GB1996/002247 WO1997010227A1 (fr) | 1995-09-15 | 1996-09-12 | Derives de la benzothiazolone |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EE9800069A EE9800069A (et) | 1998-10-15 |
| EE03395B1 true EE03395B1 (et) | 2001-04-16 |
Family
ID=26307771
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EE9800069A EE03395B1 (et) | 1995-09-15 | 1996-09-12 | Bensotiasolooni derivaadid, protsessid ja kasutatud vaheühendid nende saamiseks ning neid sisaldavad ravimkoostised |
Country Status (28)
| Country | Link |
|---|---|
| US (5) | US5846989A (fr) |
| EP (1) | EP0850232B1 (fr) |
| JP (1) | JP3213327B2 (fr) |
| KR (1) | KR19990044674A (fr) |
| CN (2) | CN1073098C (fr) |
| AR (1) | AR004512A1 (fr) |
| AT (1) | ATE190610T1 (fr) |
| AU (1) | AU706094B2 (fr) |
| BR (1) | BR9610316A (fr) |
| CA (1) | CA2231003A1 (fr) |
| CY (1) | CY2227B1 (fr) |
| CZ (1) | CZ74098A3 (fr) |
| DE (1) | DE69607183T2 (fr) |
| EE (1) | EE03395B1 (fr) |
| ES (1) | ES2146901T3 (fr) |
| GR (1) | GR3033681T3 (fr) |
| HU (1) | HUP9802393A3 (fr) |
| IL (4) | IL141954A0 (fr) |
| IS (1) | IS4679A (fr) |
| MY (1) | MY113518A (fr) |
| NO (1) | NO310721B1 (fr) |
| NZ (4) | NZ318007A (fr) |
| PL (1) | PL325517A1 (fr) |
| PT (1) | PT850232E (fr) |
| SK (1) | SK282394B6 (fr) |
| TR (1) | TR199800457T2 (fr) |
| TW (1) | TW356468B (fr) |
| WO (1) | WO1997010227A1 (fr) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL193215B1 (pl) * | 1997-10-17 | 2007-01-31 | Eurogene Ltd | Zastosowanie lipofilnych inhibitorów układu renina-angiotensyna |
| SE0004750D0 (sv) * | 2000-12-19 | 2000-12-19 | Astrazeneca Ab | Novel formulation |
| GB0218629D0 (en) * | 2002-08-09 | 2002-09-18 | Novartis Ag | Organic compounds |
| AR040962A1 (es) * | 2002-08-09 | 2005-04-27 | Novartis Ag | Compuestos derivados de tiazol 1,3-2-ona, composicion farmaceutica y proceso de preparacion del compuesto |
| US7345060B2 (en) * | 2003-11-21 | 2008-03-18 | Theravance, Inc. | Compounds having β2 adrenergic receptor agonist and muscarinic receptor antagonist activity |
| GB0426164D0 (en) | 2004-11-29 | 2004-12-29 | Novartis Ag | Organic compounds |
| CN101282950B (zh) * | 2005-08-09 | 2012-09-12 | 阿斯利康(瑞典)有限公司 | 新颖的苯并噻唑酮衍生物 |
| TW200738658A (en) * | 2005-08-09 | 2007-10-16 | Astrazeneca Ab | Novel compounds |
| RU2415136C2 (ru) * | 2005-08-09 | 2011-03-27 | Астразенека Аб | Новые производные бензотиазолона |
| TW200740781A (en) * | 2005-08-29 | 2007-11-01 | Astrazeneca Ab | Novel compounds |
| TW200745067A (en) | 2006-03-14 | 2007-12-16 | Astrazeneca Ab | Novel compounds |
| TW200833670A (en) * | 2006-12-20 | 2008-08-16 | Astrazeneca Ab | Novel compounds 569 |
| MX2009006010A (es) * | 2006-12-20 | 2009-06-16 | Astrazeneca Ab | Derivados de amina y su uso en enfermedades mediadas por el adrenoreceptor beta 2. |
| GB0702458D0 (en) | 2007-02-08 | 2007-03-21 | Astrazeneca Ab | Salts 668 |
| JP2011524896A (ja) | 2008-06-18 | 2011-09-08 | アストラゼネカ・アクチエボラーグ | 呼吸器障害の処置用のベータ2−アドレナリン受容体アゴニストとして作用するベンズオキサジノン誘導体 |
| AU2009260904A1 (en) * | 2008-06-20 | 2009-12-23 | Astrazeneca Ab | Pharmaceutical composition comprising a 4-hydroxy-2-oxo-2, 3- dihydro-1, 3-benzothiazol-7-yl compound for modulation of beta2-adrenoreceptor activity |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4314944A (en) * | 1980-08-22 | 1982-02-09 | Smithkline Corporation | 4-Aminoalkyl-7-hydroxy-2(3H)-indolones |
| US4452808A (en) * | 1982-12-07 | 1984-06-05 | Smithkline Beckman Corporation | 4-Aminoalkyl-2(3H)-indolones |
| GB8426200D0 (en) * | 1984-10-17 | 1984-11-21 | Glaxo Holdings Ltd | Chemical compounds |
| US4554284A (en) * | 1984-09-12 | 1985-11-19 | Smithkline Beckman Corporation | 7-(2-Aminoethyl)-1,3-benzthia- or oxa-zol-2(3H)-ones |
| US4554287A (en) * | 1984-09-12 | 1985-11-19 | Smithkline Beckman Corporation | Antihypertensive 7-[2-(dialkylamino)ethyl]-4-hydroxy-1,3-benzimidazol-2-ones |
| DK514585A (da) * | 1984-11-08 | 1986-05-09 | Syntex Inc | Aminoethylanilinderivater |
| DE3728695A1 (de) * | 1987-08-25 | 1989-03-09 | Schering Ag | Neue benzimidazol-derivate |
| GB9024208D0 (en) * | 1990-11-07 | 1990-12-19 | Salutar Inc | Compounds |
| IE914003A1 (en) * | 1990-11-20 | 1992-05-20 | Astra Pharma Prod | Biologically Active Amines |
| GB9210632D0 (en) * | 1992-05-19 | 1992-07-01 | Fisons Plc | Compounds |
| GB9211172D0 (en) * | 1992-05-27 | 1992-07-08 | Fisons Plc | Compounds |
-
1996
- 1996-09-11 TW TW085111075A patent/TW356468B/zh active
- 1996-09-12 PL PL96325517A patent/PL325517A1/xx unknown
- 1996-09-12 EP EP96930256A patent/EP0850232B1/fr not_active Expired - Lifetime
- 1996-09-12 JP JP51175297A patent/JP3213327B2/ja not_active Expired - Fee Related
- 1996-09-12 IL IL141954??A patent/IL141954A0/xx unknown
- 1996-09-12 IL IL12363996A patent/IL123639A/en not_active IP Right Cessation
- 1996-09-12 NZ NZ318007A patent/NZ318007A/xx unknown
- 1996-09-12 ES ES96930256T patent/ES2146901T3/es not_active Expired - Lifetime
- 1996-09-12 CA CA002231003A patent/CA2231003A1/fr not_active Abandoned
- 1996-09-12 KR KR1019980701929A patent/KR19990044674A/ko not_active Ceased
- 1996-09-12 IL IL14195696A patent/IL141956A0/xx unknown
- 1996-09-12 WO PCT/GB1996/002247 patent/WO1997010227A1/fr not_active Ceased
- 1996-09-12 TR TR1998/00457T patent/TR199800457T2/xx unknown
- 1996-09-12 EE EE9800069A patent/EE03395B1/xx not_active IP Right Cessation
- 1996-09-12 US US08/776,770 patent/US5846989A/en not_active Expired - Lifetime
- 1996-09-12 SK SK295-98A patent/SK282394B6/sk unknown
- 1996-09-12 AT AT96930256T patent/ATE190610T1/de not_active IP Right Cessation
- 1996-09-12 CN CN96198311A patent/CN1073098C/zh not_active Expired - Fee Related
- 1996-09-12 DE DE69607183T patent/DE69607183T2/de not_active Expired - Fee Related
- 1996-09-12 IL IL14195596A patent/IL141955A0/xx unknown
- 1996-09-12 CZ CZ98740A patent/CZ74098A3/cs unknown
- 1996-09-12 AU AU69371/96A patent/AU706094B2/en not_active Ceased
- 1996-09-12 PT PT96930256T patent/PT850232E/pt unknown
- 1996-09-12 HU HU9802393A patent/HUP9802393A3/hu unknown
- 1996-09-12 BR BR9610316A patent/BR9610316A/pt not_active Application Discontinuation
- 1996-09-13 AR ARP960104355A patent/AR004512A1/es not_active Application Discontinuation
- 1996-09-13 MY MYPI96003788A patent/MY113518A/en unknown
-
1998
- 1998-03-04 IS IS4679A patent/IS4679A/is unknown
- 1998-03-12 NO NO19981104A patent/NO310721B1/no unknown
- 1998-09-02 US US09/145,281 patent/US5973167A/en not_active Expired - Lifetime
- 1998-09-02 US US09/146,046 patent/US5977384A/en not_active Expired - Lifetime
- 1998-09-02 US US09/146,048 patent/US6080869A/en not_active Expired - Lifetime
- 1998-09-02 US US09/146,047 patent/US6008365A/en not_active Expired - Lifetime
- 1998-10-19 NZ NZ332396A patent/NZ332396A/xx unknown
- 1998-10-19 NZ NZ332397A patent/NZ332397A/xx unknown
- 1998-10-19 NZ NZ332395A patent/NZ332395A/xx unknown
-
2000
- 2000-06-14 GR GR20000401368T patent/GR3033681T3/el not_active IP Right Cessation
- 2000-12-30 CN CN00137051A patent/CN1356323A/zh active Pending
-
2001
- 2001-07-20 CY CY0100016A patent/CY2227B1/xx unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EE200000791A (et) | Uudsed atsüülpseudopeptiidid, nende valmistamise meetod ja neid sisaldavad farmatseutilised kompositsioonid | |
| EE200000707A (et) | Oksasolidinooni derivaadid, nende valmistamismeetod ja neid sisaldavad farmatseutilised kompositsioonid | |
| EE04498B1 (et) | Erütromütsiini derivaadid, nende valmistamismeetod ja neid sisaldav farmatseutiline kompositsioon | |
| FI973148A7 (fi) | Substituoituja heterosyklisiä yhdisteitä, menetelmä niiden valmistamis eksi ja niitä sisältäviä farmaseuttisia koostumuksia | |
| EE200000168A (et) | Karboksamidotiasoolderivaadid, nende valmistamine ja neid sisaldavad farmatseutilised kompositsioonid | |
| EE03263B1 (et) | Erütromütsiini derivaadid, nende valmistamismeetod, farmatseutiline kompositsioon ja vaheühendid | |
| EE03608B1 (et) | Taksoidid, meetod nende valmistamiseks ja neid sisaldavad farmatseutilised kompositsioonid | |
| FI963566A7 (fi) | Uusia piperatsiinijohdoksia, menetelmiä niiden valmistamiseksi ja niitä sisältäviä koostumuksia | |
| EE9700333A (et) | Substitueeritud 4-fenüülaminotiasoolid, nende valmistamise meetod ja neid sisaldavad farmakoloogilised kompositsioonid | |
| FI952550A7 (fi) | Uudet N-pyridyylikarboksamidit ja johdannaiset, menetelmät niiden valmistamiseksi ja niitä sisältävät farmaseuttiset koostumukset | |
| FI953898L (fi) | Glysiiniamidijohdannaisia, menetelmiä niiden valmistamiseksi ja niitä sisältäviä lääkeaineita | |
| FI954304A7 (fi) | Uudet bentsopyraanijohdannaiset, menetelmä niiden valmistamiseksi ja niitä sisältävät farmaseuttiset koostumukset | |
| EE9800426A (et) | Asendatud 2,4-tiasolidiindiooni derivaadid, nende valmistamismeetodid ja neid sisaldavad farmatseutilised kompositsioonid | |
| EE03395B1 (et) | Bensotiasolooni derivaadid, protsessid ja kasutatud vaheühendid nende saamiseks ning neid sisaldavad ravimkoostised | |
| FI943688L (fi) | Uudet 11-bentsaldoksiimi-17beta-metoksi-27alfa-metoksi-metyyli-estradieenijohdannaiset, menetelmät niiden valmistamiseksi ja näitä sisältävät lääkeaineet | |
| FI955023L (fi) | Uudet trisykliset amidiyhdisteet, menetelmät niiden valmistamiseksi ja niitä sisältävät farmaseuttiset koostumukset | |
| FI950625A7 (fi) | Polysubstituoituja 3-asyyliamino-5-fenyyli-1,4-bentsodiatsepiini-2-onijohdannaisia, menetelmä niiden valmistamiseksi ja niitä sisältäviä farmaseuttisia koostumuksia | |
| FI956278L (fi) | Substituoituja 4-fenyylitiatsolijohdannaisia, menetelmä niiden valmistamiseksi ja niitä sisältäviä farmaseuttisia koostumuksia | |
| EE03611B1 (et) | Taksoidid, nende valmistamismeetod ja neid sisaldavad farmatseutilised kompositsioonid | |
| EE200100173A (et) | 2-fenüülpüraan-4-ooni derivaadid, nende valmistamismeetod ja kasutamine, vaheühendite kasutamine jafarmatseutiline kompositsioon | |
| FI950817A7 (fi) | Uudet bentsodioksaaniyhdisteet, menetelmä niiden valmistamiseksi ja niitä sisältävät farmaseuttiset koostumukset | |
| FI960316L (fi) | Oksatiolaanit, menetelmä niiden valmistamiseksi ja niitä sisältävät farmaseuttiset koostumukset | |
| FI953308A7 (fi) | Uudet bentsopyraaniyhdisteet, menetelmä niiden valmistamiseksi ja niitä sisältävät farmaseuttiset koostumukset | |
| FI951091A7 (fi) | Uudet alkyyliaminoindaaniyhdisteet, menetelmät niiden valmistamiseksi ja niitä sisältävät farmaseuttiset koostumukset | |
| HUP9601712A3 (en) | Substituted benzothiazine derivatives, intermediates of them, process for their preparation and pharmaceutical compositions containing the same |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB4A | Valid patent at the end of a year |
Effective date: 20021231 |
|
| KB4A | Valid patent at the end of a year |
Effective date: 20031231 |
|
| MM4A | Lapsed by not paying the annual fees |
Effective date: 20030912 |