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EE03492B1 - Mitte-autoinaktiveeruvad ekspressiooni suunavad retroviiruslikud vektorid - Google Patents

Mitte-autoinaktiveeruvad ekspressiooni suunavad retroviiruslikud vektorid

Info

Publication number
EE03492B1
EE03492B1 EE9700040A EE9700040A EE03492B1 EE 03492 B1 EE03492 B1 EE 03492B1 EE 9700040 A EE9700040 A EE 9700040A EE 9700040 A EE9700040 A EE 9700040A EE 03492 B1 EE03492 B1 EE 03492B1
Authority
EE
Estonia
Prior art keywords
region
auto
retroviral vectors
direct expression
inactivating retroviral
Prior art date
Application number
EE9700040A
Other languages
English (en)
Other versions
EE9700040A (et
Inventor
Henry G�nzburg Walter
Michael Saller Robert
Original Assignee
GSF-Forschungszentrum f�r Umwelt und Gesundheit GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GSF-Forschungszentrum f�r Umwelt und Gesundheit GmbH filed Critical GSF-Forschungszentrum f�r Umwelt und Gesundheit GmbH
Publication of EE9700040A publication Critical patent/EE9700040A/et
Publication of EE03492B1 publication Critical patent/EE03492B1/et

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
    • C12N2740/13041—Use of virus, viral particle or viral elements as a vector
    • C12N2740/13043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Ceramic Products (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Traffic Control Systems (AREA)
  • Navigation (AREA)
  • Road Signs Or Road Markings (AREA)
  • Molds, Cores, And Manufacturing Methods Thereof (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Electrotherapy Devices (AREA)
EE9700040A 1994-09-02 1995-09-01 Mitte-autoinaktiveeruvad ekspressiooni suunavad retroviiruslikud vektorid EE03492B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK101794 1994-09-02
PCT/EP1995/003445 WO1996007748A1 (en) 1994-09-02 1995-09-01 Non self-inactivating, expression targeted retroviral vectors

Publications (2)

Publication Number Publication Date
EE9700040A EE9700040A (et) 1997-08-15
EE03492B1 true EE03492B1 (et) 2001-08-15

Family

ID=8100062

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9700040A EE03492B1 (et) 1994-09-02 1995-09-01 Mitte-autoinaktiveeruvad ekspressiooni suunavad retroviiruslikud vektorid

Country Status (20)

Country Link
US (1) US7531353B1 (et)
EP (1) EP0779929B1 (et)
JP (1) JP4037446B2 (et)
CN (1) CN1117156C (et)
AT (1) ATE200517T1 (et)
AU (1) AU688590B2 (et)
BR (1) BR9508664A (et)
CA (1) CA2198210C (et)
DE (1) DE69520681T2 (et)
DK (1) DK0779929T5 (et)
EE (1) EE03492B1 (et)
ES (1) ES2156945T3 (et)
FI (1) FI970892A7 (et)
HU (1) HU221607B (et)
MX (1) MX9701544A (et)
NO (1) NO317731B1 (et)
NZ (1) NZ292897A (et)
PL (1) PL184375B1 (et)
RU (1) RU2199585C2 (et)
WO (1) WO1996007748A1 (et)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4037446B2 (ja) 1994-09-02 2008-01-23 ゲーエスエフ − フォルシュンクスツェントルム・フューア・ウムベルト・ウント・ゲズントハイト・ゲーエムベーハー 非自己不活化性の発現標的化レトロウイルスベクタ
DK0817858T3 (da) * 1995-03-09 2003-08-11 Gsf Forschungszentrum Umwelt Vektorer, som indeholder terapeutiske gener for antimikrobielle peptider, til anvendelse ved genterapi
JP4119952B2 (ja) 1995-06-27 2008-07-16 バヴァリアン・ノルディック・アクティーゼルスカブ ウイルス粒子産生カプセル化細胞
AU7291696A (en) * 1995-10-13 1997-04-30 Bavarian Nordic Research Institute A/S Retroviral vectors carrying senescent cell derived inhibitors 1 (sdi-1) or antisense sdi-1 nucleotide sequences
US7074398B1 (en) 1995-10-13 2006-07-11 Gsf-Forschungszentrum Fuer Umwelt Und Gesundheit Gmbh Retroviral vectors carrying senescent cell derived inhibitors 1 (SDI-1)or antisense SDI-1 nucleotide sequences
SI0892852T1 (sl) 1996-03-27 2006-04-30 Bavarian Nordic As Inkapsulirane celice, ki eksprimirajo citokrom P450 za aktiviranje predzdravila
US6540995B1 (en) 1996-03-27 2003-04-01 Bavarian Nordic Research Institute Gmbh Encapsulated cells producing cytochrome P450
WO1998032869A1 (en) * 1997-01-29 1998-07-30 Neurosearch A/S Expression vectors and methods for in vivo expression of therapeutic polypeptides
ATE528405T1 (de) * 1997-12-22 2011-10-15 Oxford Biomedica Ltd Auf dem virus der infektiösen pferdeanämie (eiav) basierende vektoren
ES2229674T3 (es) * 1998-01-06 2005-04-16 Institut Fur Virologie Teilrechtsfahiges Institut An Der Veterinarmedizinischen Universitat Wien Verctor retroviral reconstituyente (vector re con) para la expresion de genes dirigidos.
FR2778670B1 (fr) * 1998-05-18 2002-12-13 Rhone Poulenc Rorer Sa Methodes et compositions pour la production de particules virales
DE19910650A1 (de) * 1999-03-10 2000-09-21 Gsf Forschungszentrum Umwelt Auf HERV-LTR-Sequenzen basierende retrovirale Expressionsvektoren
WO2000066758A1 (en) * 1999-04-29 2000-11-09 Aarhus University Expression of heterologous genes from an ires translational cassette in retroviral vectors
WO2002064805A2 (en) * 2001-02-09 2002-08-22 Institut für Virologie Teilrechtsfähiges Institut an der Veterinärmedizinischen Universität Wien Replication competent non-mammalian retroviral vectors
DE102009021592A1 (de) * 2009-05-15 2010-11-18 Medizinische Hochschule Hannover ASLV-Vektorsystem
CN120866241A (zh) * 2025-09-28 2025-10-31 深圳细胞谷生物医药有限公司 通过稳定细胞系生产工程化类病毒颗粒的方法及其工程化类病毒颗粒

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU631554B2 (en) 1988-05-17 1992-12-03 Sloan-Kettering Institute For Cancer Research Retroviral vector
GB8919607D0 (en) * 1989-08-30 1989-10-11 Wellcome Found Novel entities for cancer therapy
WO1994029437A1 (en) * 1993-06-07 1994-12-22 University Of Medicine & Dentistry Of New Jersey Highly-efficient, self-inactivating, recombination-free, u3-free retroviral vectors
JP4037446B2 (ja) 1994-09-02 2008-01-23 ゲーエスエフ − フォルシュンクスツェントルム・フューア・ウムベルト・ウント・ゲズントハイト・ゲーエムベーハー 非自己不活化性の発現標的化レトロウイルスベクタ
AU5104096A (en) * 1995-03-09 1996-10-02 Bavarian Nordic Research Institute A/S Novel recombinant dna vectors for gene therapy
DK0817858T3 (da) * 1995-03-09 2003-08-11 Gsf Forschungszentrum Umwelt Vektorer, som indeholder terapeutiske gener for antimikrobielle peptider, til anvendelse ved genterapi
US6117681A (en) * 1995-03-29 2000-09-12 Bavarian Nordic Research Inst. A/S Pseudotyped retroviral particles
GB9510272D0 (en) 1995-05-22 1995-07-19 Isis Innovation Retroviral vectors
US7074398B1 (en) * 1995-10-13 2006-07-11 Gsf-Forschungszentrum Fuer Umwelt Und Gesundheit Gmbh Retroviral vectors carrying senescent cell derived inhibitors 1 (SDI-1)or antisense SDI-1 nucleotide sequences

Also Published As

Publication number Publication date
DE69520681T2 (de) 2001-11-29
FI970892A0 (fi) 1997-02-28
FI970892L (fi) 1997-02-28
JP4037446B2 (ja) 2008-01-23
CN1159210A (zh) 1997-09-10
JPH10507628A (ja) 1998-07-28
HUT76974A (hu) 1998-01-28
CA2198210C (en) 2006-07-11
FI970892A7 (fi) 1997-02-28
DE69520681D1 (de) 2001-05-17
BR9508664A (pt) 1998-01-06
NO970902L (no) 1997-04-24
RU2199585C2 (ru) 2003-02-27
ATE200517T1 (de) 2001-04-15
AU3520195A (en) 1996-03-27
NO317731B1 (no) 2004-12-13
EP0779929B1 (en) 2001-04-11
AU688590B2 (en) 1998-03-12
US7531353B1 (en) 2009-05-12
EE9700040A (et) 1997-08-15
CN1117156C (zh) 2003-08-06
MX9701544A (es) 1998-03-31
PL184375B1 (pl) 2002-10-31
WO1996007748A1 (en) 1996-03-14
DK0779929T5 (da) 2001-08-13
EP0779929A1 (en) 1997-06-25
HU221607B (hu) 2002-11-28
HK1001527A1 (en) 1998-06-26
PL319033A1 (en) 1997-07-21
CA2198210A1 (en) 1996-03-14
DK0779929T3 (da) 2001-05-07
NZ292897A (en) 1998-08-26
ES2156945T3 (es) 2001-08-01
NO970902D0 (no) 1997-02-27

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