ECSP14013268A - PYRIMIDINE PDE10 INHIBITORS - Google Patents
PYRIMIDINE PDE10 INHIBITORSInfo
- Publication number
- ECSP14013268A ECSP14013268A ECSP14013268A ECSP14013268A EC SP14013268 A ECSP14013268 A EC SP14013268A EC SP14013268 A ECSP14013268 A EC SP14013268A EC SP14013268 A ECSP14013268 A EC SP14013268A
- Authority
- EC
- Ecuador
- Prior art keywords
- pde10 inhibitors
- pyrimidine
- relates
- present
- compounds
- Prior art date
Links
- CZPWVGJYEJSRLH-UHFFFAOYSA-N Pyrimidine Chemical compound C1=CN=CN=C1 CZPWVGJYEJSRLH-UHFFFAOYSA-N 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 208000023105 Huntington disease Diseases 0.000 abstract 1
- 208000012902 Nervous system disease Diseases 0.000 abstract 1
- 208000025966 Neurological disease Diseases 0.000 abstract 1
- 102000004861 Phosphoric Diester Hydrolases Human genes 0.000 abstract 1
- 108090001050 Phosphoric Diester Hydrolases Proteins 0.000 abstract 1
- 208000028017 Psychotic disease Diseases 0.000 abstract 1
- 210000004227 basal ganglia Anatomy 0.000 abstract 1
- 208000015114 central nervous system disease Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000004064 dysfunction Effects 0.000 abstract 1
- 230000000926 neurological effect Effects 0.000 abstract 1
- 208000020016 psychiatric disease Diseases 0.000 abstract 1
- 150000003230 pyrimidines Chemical class 0.000 abstract 1
- 201000000980 schizophrenia Diseases 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invención se refiere a compuestos de pirimidina que son útiles como agentes terapéuticos para el tratamiento de trastornos del sistema nervioso central asociados con la fosfodiesterasa 10 (PDE10). La presente invención también se refiere al uso de dichos compuestos para tratar trastornos neurológicos y psiquiátricos, tales como la esquizofrenia, la psicosis o la enfermedad de Huntington, y aquellos asociados con la hipofunción del cuerpo estriado o la disfunción de los ganglios basales.The present invention relates to pyrimidine compounds that are useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 10 (PDE10). The present invention also relates to the use of said compounds to treat neurological and psychiatric disorders, such as schizophrenia, psychosis or Huntington's disease, and those associated with striated body hypofunction or basal ganglia dysfunction.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201113615273A | 2011-08-25 | 2011-08-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP14013268A true ECSP14013268A (en) | 2014-04-30 |
Family
ID=52781344
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSP14013268 ECSP14013268A (en) | 2011-08-25 | 2014-03-25 | PYRIMIDINE PDE10 INHIBITORS |
Country Status (1)
| Country | Link |
|---|---|
| EC (1) | ECSP14013268A (en) |
-
2014
- 2014-03-25 EC ECSP14013268 patent/ECSP14013268A/en unknown
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