[go: up one dir, main page]

ECSP13012467A - Uso de aglutinantes para fabricar formulaciones estables al almacenamiento - Google Patents

Uso de aglutinantes para fabricar formulaciones estables al almacenamiento

Info

Publication number
ECSP13012467A
ECSP13012467A ECSP13012467A ECSP13012467A EC SP13012467 A ECSP13012467 A EC SP13012467A EC SP13012467 A ECSP13012467 A EC SP13012467A EC SP13012467 A ECSP13012467 A EC SP13012467A
Authority
EC
Ecuador
Prior art keywords
storage
manufacture
binders
formulations
pharmaceutically acceptable
Prior art date
Application number
Other languages
English (en)
Inventor
Derek Allan Prater
Christof Spitzley
Gerhard Josef Heun
Alexander Schütz
Udo Hahn
Christian Leuner
Original Assignee
Euro Celtique Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43382375&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP13012467(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Euro Celtique Sa filed Critical Euro Celtique Sa
Publication of ECSP13012467A publication Critical patent/ECSP13012467A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychology (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Zoology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente invención se refiere a formas de dosificación farmacéuticas, de liberación prolongada, estables al almacenamiento, que comprenden oxicodona o una sal farmacéuticamente aceptable de la misma y naloxona o una sal farmacéuticamente aceptable de la misma, a la fabricación de las mismas así como a su uso para la administración a seres humanos.
ECSP13012467 2010-08-13 2013-02-28 Uso de aglutinantes para fabricar formulaciones estables al almacenamiento ECSP13012467A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37334410P 2010-08-13 2010-08-13
EP10172759 2010-08-13

Publications (1)

Publication Number Publication Date
ECSP13012467A true ECSP13012467A (es) 2013-03-28

Family

ID=43382375

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSP13012467 ECSP13012467A (es) 2010-08-13 2013-02-28 Uso de aglutinantes para fabricar formulaciones estables al almacenamiento

Country Status (29)

Country Link
US (2) US20130245054A1 (es)
EP (2) EP3505162A1 (es)
JP (1) JP6007176B2 (es)
KR (1) KR101518143B1 (es)
CN (1) CN103118668B (es)
AR (1) AR082688A1 (es)
AU (1) AU2011288413B2 (es)
BR (1) BR112013003150B1 (es)
CA (1) CA2805974C (es)
CH (1) CH705678B1 (es)
CL (1) CL2013000444A1 (es)
CO (1) CO6680640A2 (es)
DE (1) DE112011102708T5 (es)
DK (1) DK178702B1 (es)
EC (1) ECSP13012467A (es)
ES (1) ES2409069B2 (es)
GB (1) GB2495676B (es)
MX (1) MX355644B (es)
MY (1) MY165149A (es)
NO (1) NO20130366A1 (es)
NZ (1) NZ606123A (es)
PE (1) PE20131101A1 (es)
PH (1) PH12013500172A1 (es)
RU (1) RU2572695C2 (es)
SE (1) SE537698C2 (es)
SG (1) SG187678A1 (es)
SI (1) SI2603205T1 (es)
TW (1) TWI469781B (es)
WO (1) WO2012020097A2 (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100417489B1 (ko) 1997-12-22 2004-02-05 유로-셀티크 소시에떼 아노뉨 오피오이드 효능제／길항제 혼합물
US6375957B1 (en) 1997-12-22 2002-04-23 Euro-Celtique, S.A. Opioid agonist/opioid antagonist/acetaminophen combinations
DE60238756D1 (de) 2001-05-11 2011-02-10 Endo Pharmaceuticals Inc Opioid enthaltende arzneiform gegen missbrauch
DE20308436U1 (de) 2002-04-05 2003-09-18 Euroceltique S.A., Luxemburg/Luxembourg Lagerstabiles pharmazeutisches Präparat, das Oxycodon und Naloxon umfasst
EP1702558A1 (en) 2005-02-28 2006-09-20 Euro-Celtique S.A. Method and device for the assessment of bowel function
ES2706407T3 (es) 2009-03-10 2019-03-28 Euro Celtique Sa Composiciones farmacéuticas de liberación inmediata que comprenden oxicodona y naloxona
JP5840201B2 (ja) 2010-05-10 2016-01-06 ユーロ−セルティーク エス．エイ． 活性剤を負荷した顆粒と追加の活性剤の組合せ
MX340188B (es) 2010-05-10 2016-06-30 Euro-Celtique S A * Elaboracion de granulos sin activos y tabletas que comprenden los mismos.
US20140271893A1 (en) * 2013-03-15 2014-09-18 Mcneil-Ppc, Inc. Coated phenylephrine particles and use thereof in pharmaceutical formulations
US10071089B2 (en) 2013-07-23 2018-09-11 Euro-Celtique S.A. Combination of oxycodone and naloxone for use in treating pain in patients suffering from pain and a disease resulting in intestinal dysbiosis and/or increasing the risk for intestinal bacterial translocation
WO2015023675A2 (en) 2013-08-12 2015-02-19 Pharmaceutical Manufacturing Research Services, Inc. Extruded immediate release abuse deterrent pill
NZ719087A (en) 2013-11-13 2017-12-22 Euro Celtique Sa Hydromorphone and naloxone for treatment of pain and opioid bowel dysfunction syndrome
US9492444B2 (en) 2013-12-17 2016-11-15 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
WO2015095391A1 (en) 2013-12-17 2015-06-25 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
EP3169315B1 (en) 2014-07-17 2020-06-24 Pharmaceutical Manufacturing Research Services, Inc. Immediate release abuse deterrent liquid fill dosage form
EP3209282A4 (en) 2014-10-20 2018-05-23 Pharmaceutical Manufacturing Research Services, Inc. Extended release abuse deterrent liquid fill dosage form
CN107205943A (zh) * 2014-12-08 2017-09-26 德威洛克制药有限公司 纳洛酮单剂和多层片剂
US20180104236A1 (en) 2016-09-26 2018-04-19 Euro-Celtique S. A. Methods of treatment comprising administering a high daily dose of oxycodone and naloxone in a 2:1 weight ratio
JP7109535B2 (ja) * 2017-04-13 2022-07-29 パウル レモン，ジャン キサントフモールベースの組成物
CN111686094A (zh) * 2020-07-13 2020-09-22 云南民族大学 一种脂肪醇类化合物在制备通便药物中的应用

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0164669B1 (de) 1984-06-13 1991-01-23 Röhm Gmbh Verfahren zum Überziehen von Arzneiformen
EP2036558A3 (en) * 1993-10-07 2010-04-28 Euro-Celtique S.A. Orally administrable opioid formulations having extended duration of effect
US6245357B1 (en) * 1998-03-06 2001-06-12 Alza Corporation Extended release dosage form
JP4848558B2 (ja) * 2001-05-08 2011-12-28 トーアエイヨー株式会社 塩酸メトホルミン含有速放性錠剤
SI1416842T1 (sl) * 2001-07-18 2009-06-30 Euro Celtique Sa Farmacevtske kombinacije oksikodona in naloksona
US7332182B2 (en) * 2001-08-06 2008-02-19 Purdue Pharma L.P. Pharmaceutical formulation containing opioid agonist, opioid antagonist and irritant
JP2003160487A (ja) * 2001-11-20 2003-06-03 Ohara Yakuhin Kogyo Kk プラバスタチンナトリウム含有錠剤およびその製造法
DE20308436U1 (de) * 2002-04-05 2003-09-18 Euroceltique S.A., Luxemburg/Luxembourg Lagerstabiles pharmazeutisches Präparat, das Oxycodon und Naloxon umfasst
US20060009478A1 (en) * 2003-10-15 2006-01-12 Nadav Friedmann Methods for the treatment of back pain
EP1604666A1 (en) * 2004-06-08 2005-12-14 Euro-Celtique S.A. Opioids for the treatment of the Chronic Obstructive Pulmonary Disease (COPD)
EP1604667A1 (en) * 2004-06-08 2005-12-14 Euro-Celtique S.A. Opioids for the treatment of the restless leg syndrome
EP1695700A1 (en) * 2005-02-28 2006-08-30 Euro-Celtique S.A. Dosage form containing oxycodone and naloxone
DE102005048293A1 (de) * 2005-10-08 2007-04-12 Sanofi-Aventis Deutschland Gmbh Retardformulierung für Pralnacasan
KR100753480B1 (ko) * 2006-01-27 2007-08-31 씨제이 주식회사 잘토프로펜 함유 서방성 정제 및 그 제조방법
US8133506B2 (en) * 2008-03-12 2012-03-13 Aptalis Pharmatech, Inc. Drug delivery systems comprising weakly basic drugs and organic acids
JP2009298707A (ja) * 2008-06-11 2009-12-24 Ohara Yakuhin Kogyo Kk 粒子加工方法
DK3045043T3 (da) * 2009-02-26 2020-08-03 Relmada Therapeutics Inc Orale farmaceutiske sammensætninger af 3-hydroxy-n-methylmorphinan med forlænget frigivelse og fremgangsmåde til anvendelse

Also Published As

Publication number Publication date
JP2013533303A (ja) 2013-08-22
BR112013003150A2 (pt) 2020-09-08
CA2805974C (en) 2019-11-26
WO2012020097A3 (en) 2012-05-03
DK201370075A (en) 2013-02-13
NO20130366A1 (no) 2013-04-29
SI2603205T1 (sl) 2019-02-28
KR20130083903A (ko) 2013-07-23
EP2603205B1 (en) 2018-10-03
JP6007176B2 (ja) 2016-10-12
GB2495676A (en) 2013-04-17
BR112013003150B1 (pt) 2022-01-18
CO6680640A2 (es) 2013-05-31
RU2013110820A (ru) 2014-09-20
ES2409069R1 (es) 2013-08-30
EP3505162A1 (en) 2019-07-03
CH705678B1 (de) 2016-03-15
WO2012020097A2 (en) 2012-02-16
AR082688A1 (es) 2012-12-26
MX2013001757A (es) 2013-05-06
ES2409069A2 (es) 2013-06-24
CL2013000444A1 (es) 2013-08-23
RU2572695C2 (ru) 2016-01-20
GB2495676B (en) 2018-08-22
SG187678A1 (en) 2013-03-28
GB201301916D0 (en) 2013-03-20
CN103118668B (zh) 2016-07-06
AU2011288413B2 (en) 2014-05-22
MX355644B (es) 2018-04-26
SE537698C2 (sv) 2015-09-29
US20160095853A1 (en) 2016-04-07
AU2011288413A1 (en) 2013-02-21
US20130245054A1 (en) 2013-09-19
TWI469781B (zh) 2015-01-21
NZ606123A (en) 2015-03-27
MY165149A (en) 2018-02-28
DE112011102708T5 (de) 2013-05-29
ES2409069B2 (es) 2014-07-17
DK178702B1 (en) 2016-11-21
PE20131101A1 (es) 2013-09-23
SE1350286A1 (sv) 2013-03-21
EP2603205A2 (en) 2013-06-19
CN103118668A (zh) 2013-05-22
CA2805974A1 (en) 2012-02-16
PH12013500172A1 (en) 2022-10-24
TW201228662A (en) 2012-07-16
KR101518143B1 (ko) 2015-05-06

Similar Documents

Publication Publication Date Title
ES2409069B2 (es) Uso de aglutinantes para fabricar formulaciones estables al almacenamiento
GT201200304A (es) Composiciones farmacéuticas que comprenden hidromorfona y naloxona
DOP2012000279A (es) Composiciones farmaceuticas que comprenden hidromorfona y naloxona
EA201200937A1 (ru) Твердая лекарственная форма тикагрелора
CR20130033A (es) Formulaciones de rifaximina y usos de las mismas
CO6640305A2 (es) Elaboración de gránulos sin activos y tabletas que comprenden los mismos
CL2012001836A1 (es) Compuestos de pirazol, antagonista de crth2; composicion farmacéutica; uso en el tratamiento de trastornos inflamatorios, infecciosos, inmunoreguladores, enfermedades respiratorias, gastrointestinales o dolencias, entre otros.
CY1118032T1 (el) Διεργασιες για την εμπορικη παρασκευη φαρμακευτικα δραστικου παραγοντα
ES2446643R1 (es) Composiciones farmacéuticas combinadas y su uso para preparar un medicamento destinado al tratamiento del vértigo, la cinetosis y la distonía vegetativa-vascular
ECSP10010588A (es) Formulacion de medicamento solida con liberacion retardada
PH12012502082A1 (en) Combination of active loaded granules with additional actives
HK1208222A1 (en) Modified release formulations for oprozomib
BR112015029894A2 (pt) forma de dosagem farmacêutica sólida
BR112013007904A2 (pt) "composto, composição farmacêutica, medicamento, uso de um composto e proceso para preparar um composto"
WO2013072770A3 (en) Pharmaceutical formulations comprising atorvastatin and glimepiride
CL2011003355A1 (es) Compuestos derivados de alcoxi-carbonil-amino-alquinil-adenosina ; composición farmacéutica que los comprende; uso del compuesto en la preparación de un medicamento útil para tratar enfermedades autoinmunes, inflamatorias, alérgicas, infecciosas entre otras.
RU2011145777A (ru) Лекарственное средство, обладающее ранозаживляющей, противовоспалительной активностью
CR11781A (es) Formulacion de medicamento solida con liberacion retardada