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EA201170303A1 - Аналоги глюкозозависимого инсулинотропного полипептида - Google Patents

Аналоги глюкозозависимого инсулинотропного полипептида

Info

Publication number
EA201170303A1
EA201170303A1 EA201170303A EA201170303A EA201170303A1 EA 201170303 A1 EA201170303 A1 EA 201170303A1 EA 201170303 A EA201170303 A EA 201170303A EA 201170303 A EA201170303 A EA 201170303A EA 201170303 A1 EA201170303 A1 EA 201170303A1
Authority
EA
Eurasian Patent Office
Prior art keywords
gluose
dependent insulinotropic
insulinotropic polypeptide
polypeptide analogues
compounds
Prior art date
Application number
EA201170303A
Other languages
English (en)
Other versions
EA020005B1 (ru
Inventor
Чжэн Синь Дун
Original Assignee
Ипсен Фарма С.А.С.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ипсен Фарма С.А.С. filed Critical Ипсен Фарма С.А.С.
Publication of EA201170303A1 publication Critical patent/EA201170303A1/ru
Publication of EA020005B1 publication Critical patent/EA020005B1/ru

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/645—Secretins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
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    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
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    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
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  • Veterinary Medicine (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
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  • Pulmonology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)

Abstract

Представлена новая серия аналогов глюкозозависимого инсулинотропного пептида, фармацевтические композиции, содержащие указанные соединения, и применение указанных соединений в качестве агонистов или антагонистов рецептора GIP для лечения опосредованных рецептором GIP состояний, таких как инсулиннезависимый сахарный диабет и ожирение.
EA201170303A 2008-08-07 2009-08-07 Аналоги глюкозазависимого инсулинотропного полипептида EA020005B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18818808P 2008-08-07 2008-08-07
US20061808P 2008-12-02 2008-12-02
PCT/US2009/004550 WO2010016938A2 (en) 2008-08-07 2009-08-07 Glucose-dependent insulinotropic polypeptide analogues

Publications (2)

Publication Number Publication Date
EA201170303A1 true EA201170303A1 (ru) 2011-10-31
EA020005B1 EA020005B1 (ru) 2014-07-30

Family

ID=41664128

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201170303A EA020005B1 (ru) 2008-08-07 2009-08-07 Аналоги глюкозазависимого инсулинотропного полипептида

Country Status (12)

Country Link
US (2) US9072703B2 (ru)
EP (1) EP2323678B1 (ru)
JP (2) JP2011530507A (ru)
KR (3) KR20130133104A (ru)
CN (2) CN102170895A (ru)
AU (1) AU2009280015B2 (ru)
BR (1) BRPI0917579A2 (ru)
CA (1) CA2732973A1 (ru)
EA (1) EA020005B1 (ru)
ES (1) ES2574835T3 (ru)
MX (1) MX2011001030A (ru)
WO (1) WO2010016938A2 (ru)

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ES2574835T3 (es) 2008-08-07 2016-06-22 Ipsen Pharma S.A.S. Análogos del polipéptido insulinotrópico dependiente de glucosa

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US20150252093A1 (en) 2015-09-10
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MX2011001030A (es) 2011-04-26
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