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EA200800722A1 - Средство, активирующее стволовые клетки и/или клетки-предшественники - Google Patents

Средство, активирующее стволовые клетки и/или клетки-предшественники

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Publication number
EA200800722A1
EA200800722A1 EA200800722A EA200800722A EA200800722A1 EA 200800722 A1 EA200800722 A1 EA 200800722A1 EA 200800722 A EA200800722 A EA 200800722A EA 200800722 A EA200800722 A EA 200800722A EA 200800722 A1 EA200800722 A1 EA 200800722A1
Authority
EA
Eurasian Patent Office
Prior art keywords
cells
stem cells
thrombin
precautional
enzyme
Prior art date
Application number
EA200800722A
Other languages
English (en)
Other versions
EA014296B1 (ru
Inventor
Хиробуми Сенга
Чжунчао Хань
Динфан Цай
Ли Ли
Original Assignee
Тобиси Фармасьютикал Ко., Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Тобиси Фармасьютикал Ко., Лтд. filed Critical Тобиси Фармасьютикал Ко., Лтд.
Publication of EA200800722A1 publication Critical patent/EA200800722A1/ru
Publication of EA014296B1 publication Critical patent/EA014296B1/ru

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Abstract

Настоящее изобретение предоставляет средство, активирующее стволовые клетки и/или клетки-предшественники, включающее тромбиноподобный фермент, которое может использоваться в регенеративной медицине, и особенно в регенеративной медицине, использующей саморегенерацию, действующее быстро и умеренно в зависимости от распространенности и степени повреждения органов и/или тканей, к которым применяется регенеративная медицина, с незначительными побочными эффектами или без них. Настоящее изобретение также предоставляет способ активации стволовых клеток и/или клеток-предшественников у животного, включающий стадию введения животному эффективного количества тромбиноподобного фермента и использование тромбиноподобного фермента для активации стволовых клеток и/или клеток-предшественников .
EA200800722A 2005-09-30 2006-10-02 Средство, активирующее стволовые клетки и/или клетки-предшественники EA014296B1 (ru)

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PCT/JP2006/320148 WO2007037561A1 (en) 2005-09-30 2006-10-02 Activating agent of stem cells and/or progenitor cells

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US8747905B2 (en) * 2006-10-27 2014-06-10 Emory University Therapeutic use of CD31 expressing cells
TWI482629B (zh) * 2008-07-01 2015-05-01 Tobishi Pharmaceutical Co 下泌尿道疾病治療劑及下泌尿道症狀改善劑
CN103040860B (zh) 2012-11-29 2018-08-14 刘学武 一种启动哺乳动物干细胞的方法及二氧化氯在制备用于启动哺乳动物干细胞的药物的应用
KR101662405B1 (ko) * 2013-12-12 2016-10-05 사회복지법인 삼성생명공익재단 줄기세포 유래 엑소좀을 유효성분으로 포함하는 뇌혈관 질환 치료용 약학적 조성물
KR101970642B1 (ko) * 2016-04-06 2019-05-17 주식회사 제이제이메이딘 줄기세포 배양용 배지조성물 및 그를 이용한 줄기세포 배양방법
JP7100854B2 (ja) 2017-01-13 2022-07-14 東菱薬品工業株式会社 好中球活性化調節剤
CN114134108A (zh) * 2021-11-30 2022-03-04 武汉伯韬生物科技有限公司 一种干细胞生物活性组合物及其制备方法
CN119639664A (zh) * 2024-12-09 2025-03-18 南开大学 一种基质赋能间充质干细胞的聚集体及应用

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JP3866800B2 (ja) * 1996-08-29 2007-01-10 東菱薬品工業株式会社 アポトーシス関連疾患の予防及び／又は治療薬
WO2005045022A1 (en) * 2003-10-31 2005-05-19 Biobud Co., Ltd. Thrombin-like recombinant batroxobin expressed by pichia sp.and production method thereof
JPWO2005090550A1 (ja) * 2004-03-18 2008-02-07 株式会社バイオマスター 幹細胞の増殖法

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WO2007037561A1 (en) 2007-04-05
EP1929006B1 (en) 2014-12-03
HK1114641A1 (en) 2008-11-07
KR101777414B1 (ko) 2017-09-11
CA2623950C (en) 2016-01-26
CA2623950A1 (en) 2007-04-05
CN101278045B (zh) 2016-03-23
CN101278045A (zh) 2008-10-01
AU2006295607B2 (en) 2010-12-16
JP2009509914A (ja) 2009-03-12
US20100034803A1 (en) 2010-02-11
EP1929006A1 (en) 2008-06-11
WO2007037561A9 (en) 2007-05-31
JP5602364B2 (ja) 2014-10-08
AU2006295607A1 (en) 2007-04-05
KR20080036594A (ko) 2008-04-28
EA014296B1 (ru) 2010-10-29

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