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EA200701455A1 - Система для обнаружения флуоресценции - Google Patents

Система для обнаружения флуоресценции

Info

Publication number
EA200701455A1
EA200701455A1 EA200701455A EA200701455A EA200701455A1 EA 200701455 A1 EA200701455 A1 EA 200701455A1 EA 200701455 A EA200701455 A EA 200701455A EA 200701455 A EA200701455 A EA 200701455A EA 200701455 A1 EA200701455 A1 EA 200701455A1
Authority
EA
Eurasian Patent Office
Prior art keywords
samples
fluorescence
photodetector
excitation source
detection system
Prior art date
Application number
EA200701455A
Other languages
English (en)
Other versions
EA013886B1 (ru
Inventor
Уильям Д. Дж. Бикмор
Дэнверн Рэй Робертс
Original Assignee
ЭДВАНСТ МОЛЕКУЛАР СИСТЕМС, ЭлЭлСи
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ЭДВАНСТ МОЛЕКУЛАР СИСТЕМС, ЭлЭлСи filed Critical ЭДВАНСТ МОЛЕКУЛАР СИСТЕМС, ЭлЭлСи
Publication of EA200701455A1 publication Critical patent/EA200701455A1/ru
Publication of EA013886B1 publication Critical patent/EA013886B1/ru

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates

Landscapes

  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Optical Measuring Cells (AREA)

Abstract

Описаны устройство и способы для возбуждения и обнаружения флуоресценции в образцах. Один из вариантов осуществления устройства включает держатель для удержания образцов, оптический манифольд, содержащий источник возбуждения и/или фотоприемник для каждого из образцов. В другом варианте осуществления оптический манифольд содержит только источник возбуждения или только фотоприемник, соответственно закрепленный на держателе образца. Данная система обеспечивает быстрое возбуждение и измерение флуоресценции без применения подвижных частей и без оптомеханических или электронных помех. Данная система демонстрирует исключительно хорошее отношение сигнал/шум, которое позволяет ей регистрировать очень малые различия в уровнях флуоресценции.
EA200701455A 2005-01-07 2005-12-20 Система для обнаружения флуоресценции EA013886B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/031,526 US7315376B2 (en) 2005-01-07 2005-01-07 Fluorescence detection system
PCT/US2005/046203 WO2006073811A2 (en) 2005-01-07 2005-12-20 Fluorescence detection system

Publications (2)

Publication Number Publication Date
EA200701455A1 true EA200701455A1 (ru) 2008-02-28
EA013886B1 EA013886B1 (ru) 2010-08-30

Family

ID=36647986

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200701455A EA013886B1 (ru) 2005-01-07 2005-12-20 Система для обнаружения флуоресценции

Country Status (11)

Country Link
US (1) US7315376B2 (ru)
EP (2) EP2790010A1 (ru)
JP (1) JP2008536092A (ru)
CN (1) CN101166966B (ru)
AU (1) AU2005323160A1 (ru)
BR (1) BRPI0518510A2 (ru)
CA (1) CA2593814A1 (ru)
EA (1) EA013886B1 (ru)
MX (1) MX2007008315A (ru)
WO (1) WO2006073811A2 (ru)
ZA (1) ZA200705549B (ru)

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Also Published As

Publication number Publication date
US7315376B2 (en) 2008-01-01
US20060152727A1 (en) 2006-07-13
EP1844320B1 (en) 2014-06-04
EP1844320A2 (en) 2007-10-17
JP2008536092A (ja) 2008-09-04
WO2006073811A2 (en) 2006-07-13
EP2790010A1 (en) 2014-10-15
WO2006073811A3 (en) 2007-11-01
AU2005323160A1 (en) 2006-07-13
EA013886B1 (ru) 2010-08-30
CN101166966B (zh) 2011-11-09
MX2007008315A (es) 2007-10-23
CA2593814A1 (en) 2006-07-13
BRPI0518510A2 (pt) 2008-11-25
CN101166966A (zh) 2008-04-23
EP1844320A4 (en) 2010-03-03
ZA200705549B (en) 2008-10-29

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