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EA200701305A1 - Иммуногенные композиции, содержащие циклические пептиды, полученные из бета-амилоидного пептида - Google Patents

Иммуногенные композиции, содержащие циклические пептиды, полученные из бета-амилоидного пептида

Info

Publication number
EA200701305A1
EA200701305A1 EA200701305A EA200701305A EA200701305A1 EA 200701305 A1 EA200701305 A1 EA 200701305A1 EA 200701305 A EA200701305 A EA 200701305A EA 200701305 A EA200701305 A EA 200701305A EA 200701305 A1 EA200701305 A1 EA 200701305A1
Authority
EA
Eurasian Patent Office
Prior art keywords
immunogenous
amyloid peptide
compositions containing
beta amyloid
containing cyclic
Prior art date
Application number
EA200701305A
Other languages
English (en)
Other versions
EA010586B1 (ru
Inventor
Ринальдо Цурбригген
Original Assignee
Певион Биотех Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Певион Биотех Лтд. filed Critical Певион Биотех Лтд.
Publication of EA200701305A1 publication Critical patent/EA200701305A1/ru
Publication of EA010586B1 publication Critical patent/EA010586B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Neurology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Настоящее изобретение относится к способам и композициям для вызова специфичного иммунного ответа против амилоидных бета-пептидов, в частности, путем комбинированного использования виросом в качестве адъювантов и синтетического антигена бета-амилоидного пептида.
EA200701305A 2004-12-30 2005-12-21 Иммуногенные композиции, содержащие циклические пептиды, полученные из бета-амилоидного пептида EA010586B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04031023A EP1676859A1 (en) 2004-12-30 2004-12-30 Immunogenic compositions of cyclic peptides derived from the beta-amyloid peptide
PCT/EP2005/013823 WO2006069718A1 (en) 2004-12-30 2005-12-21 Immunogenic compositions of cyclic peptides derived from the beta-amyloid peptide

Publications (2)

Publication Number Publication Date
EA200701305A1 true EA200701305A1 (ru) 2007-12-28
EA010586B1 EA010586B1 (ru) 2008-10-30

Family

ID=34928060

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200701305A EA010586B1 (ru) 2004-12-30 2005-12-21 Иммуногенные композиции, содержащие циклические пептиды, полученные из бета-амилоидного пептида

Country Status (7)

Country Link
US (1) US20080107649A1 (ru)
EP (2) EP1676859A1 (ru)
AU (1) AU2005321495A1 (ru)
CA (1) CA2592690A1 (ru)
EA (1) EA010586B1 (ru)
WO (1) WO2006069718A1 (ru)
ZA (1) ZA200705179B (ru)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10303974A1 (de) 2003-01-31 2004-08-05 Abbott Gmbh & Co. Kg Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung
CA2628703C (en) 2005-11-30 2019-10-29 Abbott Laboratories Anti-a.beta. globulomer antibodies, antigen-binding moieties thereof, corresponding hybridomas, nucleic acids, vectors, host cells, methods of producing said antibodies, compositions comprising said antibodies, uses of said antibodies and methods of using said antibodies
DK1976877T4 (en) 2005-11-30 2017-01-16 Abbvie Inc Monoclonal antibodies to amyloid beta protein and uses thereof
ES2551604T3 (es) 2005-12-12 2015-11-20 Ac Immune S.A. Vacuna terapéutica
CA2649296A1 (en) 2006-04-13 2007-10-25 Peptimmune, Inc. Methods for designing and synthesizing directed sequence polymer compositions via the directed expansion of epitope permeability
US9499601B2 (en) 2006-07-12 2016-11-22 Agency For Science, Technology And Research Molecular probe for sphingolipids
US8455626B2 (en) 2006-11-30 2013-06-04 Abbott Laboratories Aβ conformer selective anti-aβ globulomer monoclonal antibodies
WO2008104386A2 (en) 2007-02-27 2008-09-04 Abbott Gmbh & Co. Kg Method for the treatment of amyloidoses
JP2010540410A (ja) * 2007-05-07 2010-12-24 ペプティミューン，インコーポレイテッド 抗体リガンドとしての使用のためのエピトープの定方向拡大のための方法
AU2008311897B2 (en) 2007-10-16 2015-03-26 Declion Holdings Llc Methods for designing and preparing vaccines comprising directed sequence polymer compositions via the directed expansion of epitopes
EP2106802A1 (en) * 2008-04-02 2009-10-07 SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. Modified peptides as synthetic vaccines in amyloid-associated disease
EP2278998A1 (en) * 2008-04-17 2011-02-02 Declion Pharmaceuticals, Inc. Design and synthesis of directed sequence polymer compositions and antibodies thereof for the treatment of protein conformational disorders
RU2546234C2 (ru) * 2008-07-01 2015-04-10 Де Стат Дер Недерланден, Верт.Дор Де Министер Ван Ввс Вакцина против интермедиата с амилоидным сворачиванием
CN102203124A (zh) * 2008-07-25 2011-09-28 雅培制药有限公司 淀粉状蛋白β肽类似物，其寡聚物，用于制备的方法以及包括所述类似物或寡聚物的组合物，及其用途
CN104744591B (zh) 2010-04-15 2022-09-27 Abbvie德国有限责任两合公司 β淀粉样蛋白结合蛋白
US20120016598A1 (en) * 2010-05-21 2012-01-19 Bruker Daltonik Gmbh Normalization of mass spectra acquired by mass spectrometric imaging
WO2011156003A2 (en) 2010-06-09 2011-12-15 New York University Peptoid and synthetic oligomers, pharmaceutical compositions and methods of using same
WO2012024187A1 (en) 2010-08-14 2012-02-23 Abbott Laboratories Amyloid-beta binding proteins
US20120089291A1 (en) * 2010-10-12 2012-04-12 Halder Bibhrajit Autonomous machine control system
WO2017079835A1 (en) * 2015-11-09 2017-05-18 The University Of British Columbia Amyloid beta epitopes and antibodies thereto
EP3374381A4 (en) * 2015-11-09 2019-05-15 The University Of British Columbia EPITOPES IN THE AMYLOID-BETA MEDIUM REGION AND CONFORMITY-SELECTIVE ANTIBODIES THEREOF
EP3374379A4 (en) * 2015-11-09 2019-05-15 The University Of British Columbia N-TERMINAL EPITOPES IN AMYLOID BETA AND CONFORMATION-SELECTIVE ANTIBODIES
CN109476729A (zh) 2016-07-18 2019-03-15 英属哥伦比亚大学 淀粉样蛋白β的抗体
US20180125920A1 (en) 2016-11-09 2018-05-10 The University Of British Columbia Methods for preventing and treating A-beta oligomer-associated and/or -induced diseases and conditions
US12286469B2 (en) 2017-07-18 2025-04-29 The University Of British Columbia Humanized antibodies binding to amyloid-beta (A-beta)
CA3167073A1 (en) * 2020-03-10 2021-09-16 Preeti BAKRANIA Cyclic peptides

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10101430B4 (de) * 2001-01-13 2008-10-02 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Lösliche cyclische Analoga zur Modulation der Amyloidogenese

Also Published As

Publication number Publication date
ZA200705179B (en) 2008-08-27
EP1831251A1 (en) 2007-09-12
US20080107649A1 (en) 2008-05-08
CA2592690A1 (en) 2006-07-06
WO2006069718A1 (en) 2006-07-06
AU2005321495A1 (en) 2006-07-06
EP1676859A1 (en) 2006-07-05
EA010586B1 (ru) 2008-10-30
WO2006069718A9 (en) 2007-08-16

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): RU