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EA200200875A1 - Пролекарства производных имидазопиридина - Google Patents

Пролекарства производных имидазопиридина

Info

Publication number
EA200200875A1
EA200200875A1 EA200200875A EA200200875A EA200200875A1 EA 200200875 A1 EA200200875 A1 EA 200200875A1 EA 200200875 A EA200200875 A EA 200200875A EA 200200875 A EA200200875 A EA 200200875A EA 200200875 A1 EA200200875 A1 EA 200200875A1
Authority
EA
Eurasian Patent Office
Prior art keywords
imidazopiridine
procare
products
international
application
Prior art date
Application number
EA200200875A
Other languages
English (en)
Other versions
EA005597B1 (ru
Inventor
Вольфганг-Александер Зимон
Штефан Постиус
Райнхард Хубер
Вольфганг Кромер
Йёрг Зенн-Билфингер
Вильм Бур
Original Assignee
Алтана Фарма Аг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Алтана Фарма Аг filed Critical Алтана Фарма Аг
Publication of EA200200875A1 publication Critical patent/EA200200875A1/ru
Publication of EA005597B1 publication Critical patent/EA005597B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

В заявке описаны соединения формулы (1), в которых заместители имеют значения, указанные в описании, и которые могут быть использованы для профилактики и лечения заболеваний желудочно-кишечного тракта.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA200200875A 2000-03-29 2001-03-28 Пролекарства производных имидазопиридина EA005597B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00106695 2000-03-29
PCT/EP2001/003514 WO2001072756A1 (en) 2000-03-29 2001-03-28 Prodrugs of imidazopyridine derivatives

Publications (2)

Publication Number Publication Date
EA200200875A1 true EA200200875A1 (ru) 2003-04-24
EA005597B1 EA005597B1 (ru) 2005-04-28

Family

ID=8168271

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200200875A EA005597B1 (ru) 2000-03-29 2001-03-28 Пролекарства производных имидазопиридина

Country Status (25)

Country Link
US (2) US20030125327A1 (ru)
EP (1) EP1313740B1 (ru)
JP (1) JP2003528878A (ru)
KR (1) KR100860627B1 (ru)
CN (1) CN1214030C (ru)
AT (1) ATE311389T1 (ru)
AU (1) AU783633B2 (ru)
BR (1) BR0109483A (ru)
CA (1) CA2404474A1 (ru)
CZ (1) CZ20023194A3 (ru)
DE (1) DE60115466T2 (ru)
DK (1) DK1313740T3 (ru)
EA (1) EA005597B1 (ru)
ES (1) ES2253376T3 (ru)
HR (1) HRP20020854A2 (ru)
HU (1) HUP0302331A2 (ru)
IL (2) IL151200A0 (ru)
MX (1) MXPA02009551A (ru)
NO (1) NO20024662L (ru)
NZ (1) NZ520837A (ru)
PL (1) PL365116A1 (ru)
SI (1) SI1313740T1 (ru)
SK (1) SK286850B6 (ru)
WO (1) WO2001072756A1 (ru)
ZA (1) ZA200207637B (ru)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE332302T1 (de) * 2000-03-29 2006-07-15 Altana Pharma Ag Alkylierte imidazopyridinderivate
SK5072003A3 (en) 2000-10-25 2003-09-11 Altana Pharma Ag Polysubstituted imidazopyridines as gastric secretion inhibitors
US20050020637A1 (en) * 2001-11-19 2005-01-27 Wolfgang-Alexander Simon Agents for the treatment of airway disorders
US7314935B2 (en) 2002-02-15 2008-01-01 Altana Pharma Ag Tricyclic n-acyl compounds
TWI295575B (en) * 2002-04-24 2008-04-11 Altana Pharma Ag Nitrosated imidazopyridines
EP1506016A2 (en) * 2002-05-07 2005-02-16 ALTANA Pharma AG New combination of reversible proton pump inhibitors and airway therapeutics for treating airway disorders
PL375567A1 (en) 2002-11-19 2005-11-28 Altana Pharma Ag 8-substituted imidazopyridines
RS20050449A (sr) * 2002-12-20 2007-11-15 Altana Pharma Ag., 8-trialkisiloksi-2-metil-9-fenil-7- okso-7,8,9,10- tetrahidroimidazo /1,2h//1,7/naftiridini
RS20050603A (sr) * 2003-02-17 2007-09-21 Altana Pharma Ag., NOVE KOMBINACIJE I NOVA PRIMENA FARMACEUTSKIH AKTIVNIH JEDINjENjA
AR044129A1 (es) 2003-05-06 2005-08-24 Altana Pharma Ag Compuestos intermedios de imidazopiridina. proceso de preparacion.
SA04250092B1 (ar) * 2003-05-14 2008-05-04 التانا فاروا ايه جي مركب وسيط جديد لتحضير مركبات إيميدازوبيريدين imidazopyridines فعالة علاجياً
US20060241134A1 (en) * 2003-05-27 2006-10-26 Altana Pharma Ga Pharmaceutical combinations of a proton pump inhibitor and a compound which modifies gastrointestinal motility
EP1974730A1 (en) 2003-11-03 2008-10-01 AstraZeneca AB Imidazo[1,2-a]pyridine derivatives for use in the treatment of sleep disturbance due to silent gastro-esophageal reflux
AR046893A1 (es) * 2003-12-16 2005-12-28 Altana Pharma Ag Bencimidazoles triciclicos
US7326784B2 (en) 2003-12-19 2008-02-05 Altana Pharma Ag Intermediates for the preparation of tricyclic dihydropyrano-imidazo-pyridines derivatives
JP2008507487A (ja) * 2004-07-23 2008-03-13 ディーエスエム アイピー アセッツ ビー．ブイ． （２ｒ，３ｒ）−２−ヒドロキシ−３−アミノ−３−アリール−プロピオンアミドおよび（２ｒ，３ｒ）−２−ヒドロキシ−３−アミノ−３−アリール−プロピオン酸アルキルエステルの調製方法
WO2006037748A1 (en) * 2004-10-01 2006-04-13 Altana Pharma Ag Substituted tricyclic benzimidazoles
KR101605063B1 (ko) 2009-07-09 2016-03-21 라퀄리아 파마 인코포레이티드 소화관 운동이상이 관여하는 질환의 치료용 산 펌프 길항제

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4468400A (en) * 1982-12-20 1984-08-28 Schering Corporation Antiulcer tricyclic imidazo [1,2-a]pyridines
US4673679A (en) * 1986-05-14 1987-06-16 E. I. Du Pont De Nemours And Company Use of prodrugs of 3-hydroxymorphinans to prevent bitter taste upon buccal, nasal or sublingual administration
US5432183A (en) * 1991-05-31 1995-07-11 Pfizer Inc. Use of rapamycin prodrugs as immunosuppressant agents
DE4308095A1 (de) * 1993-03-13 1994-09-15 Hoechst Ag Prodrug-Derivate von Arzneimittelwirkstoffen mit Hydroxylgruppen, Verfahren zu deren Herstellung und ihre Verwendung
SE9401197D0 (sv) * 1994-04-11 1994-04-11 Astra Ab Active compounds
US6073004A (en) 1996-12-17 2000-06-06 Ericsson Inc. Emergency call initiator
CZ290548B6 (cs) * 1997-03-24 2002-08-14 Byk Gulden Lomberg Chemische Fabrik Gmbh Tetrahydropyridinové deriváty a farmaceutický prostředek
ATE400577T1 (de) * 1997-05-28 2008-07-15 Nycomed Gmbh Anellierte dihydropyrane
HUP0001555A3 (en) * 1997-10-30 2001-01-29 Altana Pharma Ag Tetrahydro-imidazo-naphthyridine derivatives, pharmaceutical compositions thereof and process for their preparation
US6436953B1 (en) * 1998-09-23 2002-08-20 Byk Gulden Lomberg Chemische Fabrik Gmbh Tetrahydropyridoethers
US6384048B1 (en) * 1998-11-03 2002-05-07 Byk Gulden Lomberg Chemische Fabrik Gmbh Imidazonaphthyridines
ATE332302T1 (de) 2000-03-29 2006-07-15 Altana Pharma Ag Alkylierte imidazopyridinderivate

Also Published As

Publication number Publication date
US7189736B2 (en) 2007-03-13
ATE311389T1 (de) 2005-12-15
DK1313740T3 (da) 2006-04-03
NO20024662D0 (no) 2002-09-27
JP2003528878A (ja) 2003-09-30
KR100860627B1 (ko) 2008-09-29
WO2001072756A1 (en) 2001-10-04
IL151200A0 (en) 2003-04-10
CA2404474A1 (en) 2001-10-04
EA005597B1 (ru) 2005-04-28
SI1313740T1 (sl) 2006-04-30
KR20020084262A (ko) 2002-11-04
EP1313740A1 (en) 2003-05-28
HK1056175A1 (en) 2004-02-06
HUP0302331A2 (hu) 2003-12-29
BR0109483A (pt) 2003-06-10
PL365116A1 (en) 2004-12-27
AU6016601A (en) 2001-10-08
SK286850B6 (sk) 2009-06-05
CZ20023194A3 (cs) 2003-01-15
SK13852002A3 (sk) 2003-02-04
CN1426414A (zh) 2003-06-25
NZ520837A (en) 2005-01-28
ES2253376T3 (es) 2006-06-01
CN1214030C (zh) 2005-08-10
DE60115466T2 (de) 2006-07-20
DE60115466D1 (de) 2006-01-05
IL151200A (en) 2009-11-18
NO20024662L (no) 2002-09-27
HRP20020854A2 (en) 2004-12-31
US20030125327A1 (en) 2003-07-03
MXPA02009551A (es) 2004-05-14
AU783633B2 (en) 2005-11-17
EP1313740B1 (en) 2005-11-30
ZA200207637B (en) 2004-04-08
US20040198764A1 (en) 2004-10-07

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ KZ KG MD TJ TM