[go: up one dir, main page]

EA200200374A1 - Производные хинолилпропилпиперидина, их получение и содержащие их композиции - Google Patents

Производные хинолилпропилпиперидина, их получение и содержащие их композиции

Info

Publication number
EA200200374A1
EA200200374A1 EA200200374A EA200200374A EA200200374A1 EA 200200374 A1 EA200200374 A1 EA 200200374A1 EA 200200374 A EA200200374 A EA 200200374A EA 200200374 A EA200200374 A EA 200200374A EA 200200374 A1 EA200200374 A1 EA 200200374A1
Authority
EA
Eurasian Patent Office
Prior art keywords
receiving
containing compositions
derivatives
quinolylpropylpiperidine derivatives
quinolylpropylpiperidine
Prior art date
Application number
EA200200374A
Other languages
English (en)
Other versions
EA005183B1 (ru
Inventor
Жан-Люк Маллерон
Мишель Табар
Жан-Кристоф Карри
Мишель Эвер
Юссеф Эль Ахмад
Серж Миньани
Фабрис Вивиани
Мишель Шеве
Original Assignee
Авентис Фарма С.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Авентис Фарма С.А. filed Critical Авентис Фарма С.А.
Publication of EA200200374A1 publication Critical patent/EA200200374A1/ru
Publication of EA005183B1 publication Critical patent/EA005183B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Изобретение относится к производным хинолилпропилпиперидина общей формулы (I), в которой Rозначает атом водорода или галогена или гидроксил; R'означает атом водорода или может означать атом галогена, когда Rтакже означает атом галогена; и R° означает атом водорода. Эти производные являются антимикробными средствами.Отчет о международном поиске был опубликован 2001.11.22.
EA200200374A 1999-09-17 2000-09-14 Производные хинолилпропилпиперидина, их получение и содержащие их композиции EA005183B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9911679A FR2798656B1 (fr) 1999-09-17 1999-09-17 Derives de la quinolyl propyl piperidine, leur preparation et les compositions qui les contiennent
PCT/FR2000/002541 WO2001025227A2 (fr) 1999-09-17 2000-09-14 Derives de la quinolyl propyl piperidine et leur utilisation en tant que antibacteriens

Publications (2)

Publication Number Publication Date
EA200200374A1 true EA200200374A1 (ru) 2002-10-31
EA005183B1 EA005183B1 (ru) 2004-12-30

Family

ID=9549990

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200200374A EA005183B1 (ru) 1999-09-17 2000-09-14 Производные хинолилпропилпиперидина, их получение и содержащие их композиции

Country Status (30)

Country Link
EP (2) EP1218370B1 (ru)
JP (1) JP2004527448A (ru)
KR (1) KR20020038757A (ru)
CN (1) CN1374959A (ru)
AP (1) AP2002002459A0 (ru)
AT (1) ATE284399T1 (ru)
AU (1) AU7429500A (ru)
BG (1) BG106524A (ru)
BR (1) BR0014060A (ru)
CA (1) CA2383836A1 (ru)
CZ (1) CZ2002940A3 (ru)
DE (2) DE60016611T2 (ru)
DZ (1) DZ3195A1 (ru)
EA (1) EA005183B1 (ru)
EE (1) EE200200138A (ru)
FR (1) FR2798656B1 (ru)
GE (1) GEP20043223B (ru)
HR (1) HRP20020214A2 (ru)
HU (1) HUP0204283A3 (ru)
IL (1) IL148720A0 (ru)
MA (1) MA26820A1 (ru)
MX (1) MXPA02001979A (ru)
NO (1) NO20021253L (ru)
OA (1) OA12022A (ru)
PL (1) PL354809A1 (ru)
SK (1) SK3632002A3 (ru)
TN (1) TNSN00184A1 (ru)
WO (1) WO2001025227A2 (ru)
YU (1) YU19002A (ru)
ZA (1) ZA200202073B (ru)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9822440D0 (en) 1998-10-14 1998-12-09 Smithkline Beecham Plc Medicaments
GB9917406D0 (en) 1999-07-23 1999-09-22 Smithkline Beecham Plc Compounds
GB9917408D0 (en) 1999-07-23 1999-09-22 Smithkline Beecham Plc Compounds
PL366335A1 (en) 2000-07-26 2005-01-24 Smithkline Beecham P.L.C. Aminopiperidine quinolines and their azaisosteric analogues with antibacterial activity
GB0031086D0 (en) * 2000-12-20 2001-01-31 Smithkline Beecham Plc Medicaments
GB0101577D0 (en) 2001-01-22 2001-03-07 Smithkline Beecham Plc Compounds
GB0112836D0 (en) 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
GB0112834D0 (en) 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
JP4445753B2 (ja) 2002-01-29 2010-04-07 グラクソ グループ リミテッド アミノピペリジン誘導体
EP1470131A2 (en) 2002-01-29 2004-10-27 Glaxo Group Limited Aminopiperidine compounds, process for their preparation, and pharmaceutical compositions containing them
TW200406413A (en) 2002-06-26 2004-05-01 Glaxo Group Ltd Compounds
AR040336A1 (es) 2002-06-26 2005-03-30 Glaxo Group Ltd Compuesto de piperidina, uso del mismo para la fabricacion de un medicamento, composicion farmaceutica que lo comprende y procedimiento para preparar dicho compuesto
FR2842807A1 (fr) 2002-07-23 2004-01-30 Aventis Pharma Sa Derives de la quinolyl propyl piperidine, procede et intermediaires de preparation et compositions les renfermant
FR2844268B1 (fr) * 2002-09-11 2004-10-22 Aventis Pharma Sa Derives de la quinolyl propyl piperidine, leurs procedes et intermediaires de preparation et les compositions qui les contiennent
FR2844270B1 (fr) * 2002-09-11 2006-05-19 Aventis Pharma Sa Derives de la quinolyl propyl piperidine, leur procede et intermediaires de preparation et les compositions qui les contiennent
BR0315221A (pt) * 2002-10-10 2005-08-23 Morphochem Ag Komb Chemie Compostos com atividade antibacteriana
WO2004096982A2 (en) 2002-11-05 2004-11-11 Smithkline Beecham Corporation Antibacterial agents
JP4654035B2 (ja) 2002-11-05 2011-03-16 グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー 抗菌剤
JP2006515862A (ja) 2002-12-04 2006-06-08 グラクソ　グループ　リミテッド キノリン類およびそれらの窒素化誘導体ならびにそれらの抗菌剤としての使用
EP1799674B1 (en) * 2004-10-05 2010-05-05 Actelion Pharmaceuticals Ltd. New piperidine antibiotics
CN101039935B (zh) * 2004-10-05 2011-04-20 埃科特莱茵药品有限公司 哌啶抗生素
JP2008528598A (ja) 2005-01-25 2008-07-31 グラクソ グループ リミテッド 抗菌剤
US7648980B2 (en) 2005-01-25 2010-01-19 Glaxo Group Limited Antibacterial agents
JP2008528587A (ja) 2005-01-25 2008-07-31 グラクソ グループ リミテッド 抗菌剤
JP2008528588A (ja) 2005-01-25 2008-07-31 グラクソ グループ リミテッド 抗菌剤
WO2007086016A1 (en) 2006-01-26 2007-08-02 Actelion Pharmaceuticals Ltd Tetrahydropyrane antibiotics
US7709483B2 (en) 2006-04-06 2010-05-04 Glaxo Group Limited Pyrrolo-quinoxalinone derivatives as antibacterials
GB0613208D0 (en) 2006-07-03 2006-08-09 Glaxo Group Ltd Compounds
EP1992628A1 (en) 2007-05-18 2008-11-19 Glaxo Group Limited Derivatives and analogs of N-ethylquinolones and N-ethylazaquinolones
CA2685888A1 (en) * 2007-05-09 2008-11-20 Pfizer Inc. Substituted heterocyclic derivatives and their pharmaceutical use and compositions
EP2080761A1 (en) 2008-01-18 2009-07-22 Glaxo Group Limited Compounds
US20110275661A1 (en) 2008-10-17 2011-11-10 Glaxo Group Limited Tricyclic nitrogen compounds used as antibacterials
ES2561631T3 (es) 2009-01-15 2016-02-29 Glaxo Group Limited Compuestos de naftiridin-2(1H)-ona útiles como agentes antibacterianos
WO2015057655A1 (en) * 2013-10-14 2015-04-23 Eisai R&D Management Co., Ltd. Selectively substituted quinoline compounds
EP3182973B1 (en) 2014-08-22 2019-09-18 GlaxoSmithKline Intellectual Property Development Limited Tricyclic nitrogen containing compounds for treating neisseria gonorrhoea infection
TW201722965A (zh) 2015-08-16 2017-07-01 葛蘭素史密斯克藍智慧財產發展有限公司 用於抗菌應用之化合物
SMT202400141T1 (it) 2015-12-17 2024-05-14 Merck Patent Gmbh 8-ciano-5-piperidino-chinoline come antagonisti di tlr7/8 e loro usi per trattamento di disturbi immunitari
JP7125385B2 (ja) 2016-08-08 2022-08-24 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング Ｔｌｒ７／８アンタゴニストおよびそれらの使用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2201674T3 (es) * 1998-01-26 2004-03-16 Smithkline Beecham Plc Derivados de quinolina con propiedades antibacterianas.
AU2437900A (en) * 1999-01-20 2000-08-07 Smithkline Beecham Plc Piperidinylquinolines as protein tyrosine kinase inhibitors

Also Published As

Publication number Publication date
EP1484328A1 (fr) 2004-12-08
EP1218370B1 (fr) 2004-12-08
EP1218370A2 (fr) 2002-07-03
CA2383836A1 (fr) 2001-04-12
CN1374959A (zh) 2002-10-16
ZA200202073B (en) 2003-08-27
EE200200138A (et) 2003-06-16
DZ3195A1 (fr) 2001-04-12
MA26820A1 (fr) 2004-12-20
DE60034713D1 (de) 2007-06-14
PL354809A1 (en) 2004-02-23
AP2002002459A0 (en) 2002-06-30
NO20021253L (no) 2002-04-24
GEP20043223B (en) 2004-04-26
BG106524A (en) 2003-01-31
FR2798656B1 (fr) 2004-12-17
NO20021253D0 (no) 2002-03-13
WO2001025227A2 (fr) 2001-04-12
DE60034713T2 (de) 2008-01-17
SK3632002A3 (en) 2003-04-01
EP1484328B1 (fr) 2007-05-02
BR0014060A (pt) 2002-05-21
ATE284399T1 (de) 2004-12-15
OA12022A (fr) 2006-04-19
FR2798656A1 (fr) 2001-03-23
DE60016611T2 (de) 2005-12-22
HUP0204283A3 (en) 2004-07-28
DE60016611D1 (de) 2005-01-13
TNSN00184A1 (fr) 2005-11-10
AU7429500A (en) 2001-05-10
HUP0204283A2 (hu) 2003-04-28
YU19002A (sh) 2005-06-10
WO2001025227A3 (fr) 2001-11-22
CZ2002940A3 (cs) 2002-07-17
KR20020038757A (ko) 2002-05-23
JP2004527448A (ja) 2004-09-09
EA005183B1 (ru) 2004-12-30
MXPA02001979A (es) 2002-08-20
HRP20020214A2 (en) 2005-04-30
IL148720A0 (en) 2002-09-12

Similar Documents

Publication Publication Date Title
EA200200374A1 (ru) Производные хинолилпропилпиперидина, их получение и содержащие их композиции
IL135536A0 (en) Ortho-anthranilamide derivatives and pharmaceutical compositions containing the same
MEP24608A (en) Azetidine derivatives, preparation thereof and pharmaceutical compositions containing same
CY1107010T1 (el) Παραγωγο βενζοϋλπυριδινης ´η αλας αυτης, μυκητοκτονο που περιεχει αυτο σαν δραστικο συστατικο, μεθοδος παρασκευης αυτου και ενδιαμεσο για παρασκευη αυτου
AU1676200A (en) Polyhydroxylated heterocyclic derivatives as anti-coagulants
TR200200579T2 (tr) Amino-tirazolpiridin türevleri.
TR200200409T2 (tr) Mantar öldürücü heterosiklik aromatik amitler ve bileşimleri, bunları kullanma ve hazırlama yöntemleri.
DK1204654T3 (da) Benzofurylpiperaziner og benzofurylhomopiperaziner: Serotonin agonister
GT200000103A (es) Trifluorbutenos nematocidas.
DE60107449D1 (de) Substituierte aminopropoxyarylderivate als lxr agonisten
EA199900937A1 (ru) Фармацевтические композиции, содержащие вориконазол
NO20004485D0 (no) Sykloalkenderivater, deres fremstilling og anvendelse
PT918776E (pt) Sintese total de acilfulvenos antitumorais
TR200002932T2 (tr) Azabisayklik 5HT1 Alıcı liganolları
AU4609701A (en) Colouring agent for keratin containing fibres
ATE117677T1 (de) Indolderivate.
TR200200125T2 (tr) Yeni aminotiyazol türevleri, bunların hazırlanması ve bunları içeren farmasötik kompozisyonlar.
BR9902084A (pt) Heterociclos.
WO2001009093A8 (en) Benzenamine derivatives as anti-coagulants
DE60041001D1 (de) Substituierte homopiperidylbenzimidazolanaloga als fundusrelaxantien
EA200200727A1 (ru) Новые производные индола
DE60119383D1 (de) Farnesyltransferasehemmende 4-heterocyclylchinolin- und chinazolinderivate
NO994107D0 (no) Preparater for behandling eller forhindring av prostatakreft
SE9901062D0 (sv) Use for conifer sapling protection
ATE261962T1 (de) Benzonaphtyridin-1,8 derivate

Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU