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EA200200126A1 - HYDRODYNAMICALLY BALANCED ORAL MEDICAL DELIVERY SYSTEM - Google Patents

HYDRODYNAMICALLY BALANCED ORAL MEDICAL DELIVERY SYSTEM

Info

Publication number
EA200200126A1
EA200200126A1 EA200200126A EA200200126A EA200200126A1 EA 200200126 A1 EA200200126 A1 EA 200200126A1 EA 200200126 A EA200200126 A EA 200200126A EA 200200126 A EA200200126 A EA 200200126A EA 200200126 A1 EA200200126 A1 EA 200200126A1
Authority
EA
Eurasian Patent Office
Prior art keywords
delivery system
gastric
medical delivery
oral medical
drug
Prior art date
Application number
EA200200126A
Other languages
Russian (ru)
Inventor
Нареш Талвар
Джон Стейнифос
Михаел Дж. Тоубин
Original Assignee
Рэнбакси Лабораториз Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Рэнбакси Лабораториз Лимитед filed Critical Рэнбакси Лабораториз Лимитед
Publication of EA200200126A1 publication Critical patent/EA200200126A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Настоящее изобретение относится к удерживающейся в желудке пероральной системе доставки лекарства, включающей высокопористую основу, содержащую, по крайней мере, одно лекарственное вещество, сахар(а), газообразующие компоненты и необязательно фармацевтически приемлемые вспомогательные компоненты. Данная фармацевтическая композиция или в форме пилюль (в виде множества частиц или в виде одиночной единой лекарственной формы), шариков, гранул или в форме капсул удерживается в желудке, в то время как лекарство(лекарства) селективно доставляется на желудочные уровни и верхние отделы тонкой кишки в течение длительного периода времени.Международная заявка была опубликована вместе с отчетом о международном поиске.The present invention relates to a gastric-retaining oral drug delivery system comprising a highly porous base containing at least one drug substance, sugar (a), blowing agents, and optionally pharmaceutically acceptable auxiliary components. This pharmaceutical composition or in pill form (in the form of a plurality of particles or in the form of a single single dosage form), spheres, granules or in the form of capsules is retained in the stomach, while the drug (s) is selectively delivered to the gastric levels and upper small intestine. over a long period of time. The international application was published along with an international search report.

EA200200126A 1999-08-04 2000-08-01 HYDRODYNAMICALLY BALANCED ORAL MEDICAL DELIVERY SYSTEM EA200200126A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/IB1999/001386 WO2001010405A1 (en) 1999-08-04 1999-08-04 Hydrodynamically balanced oral drug delivery system
PCT/IB2000/001083 WO2001010419A1 (en) 1999-08-04 2000-08-01 Hydrodynamically balancing oral drug delivery system

Publications (1)

Publication Number Publication Date
EA200200126A1 true EA200200126A1 (en) 2002-10-31

Family

ID=11004886

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200200126A EA200200126A1 (en) 1999-08-04 2000-08-01 HYDRODYNAMICALLY BALANCED ORAL MEDICAL DELIVERY SYSTEM

Country Status (21)

Country Link
EP (1) EP1206249A4 (en)
JP (1) JP2003506400A (en)
CN (1) CN1376059A (en)
AP (1) AP2002002410A0 (en)
AU (2) AU5060499A (en)
BR (1) BR0012981A (en)
CA (1) CA2378468A1 (en)
CZ (1) CZ2002415A3 (en)
EA (1) EA200200126A1 (en)
HK (1) HK1047226A1 (en)
HR (1) HRP20020108A2 (en)
HU (1) HUP0202497A3 (en)
IL (1) IL147966A0 (en)
MX (1) MXPA02001272A (en)
NZ (1) NZ516959A (en)
OA (1) OA12003A (en)
PL (1) PL353321A1 (en)
SK (1) SK1832002A3 (en)
TR (1) TR200200467T2 (en)
WO (2) WO2001010405A1 (en)
ZA (1) ZA200200926B (en)

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KR100457458B1 (en) * 2001-04-02 2004-11-17 삼아약품 주식회사 Rapidly dissolving tablet and process for preparing same
CA2452738C (en) 2001-07-04 2011-06-14 Sun Pharmaceutical Industries Limited Gastric retention controlled drug delivery system
WO2003037296A2 (en) * 2001-10-29 2003-05-08 Labopharm Inc. Methods and dosage forms for improving the bioavailability of therapeutic agents
US20050226926A1 (en) 2002-07-25 2005-10-13 Pfizer Inc Sustained-release tablet composition of pramipexole
JP2007503427A (en) * 2003-08-27 2007-02-22 ベクタ・リミテッド Composition for treating medical conditions requiring suppression of gastric acid secretion
TW200533391A (en) 2004-03-25 2005-10-16 Sun Pharmaceutical Ind Ltd Gastric retention drug delivery system
AU2005256653B2 (en) * 2004-06-28 2010-10-14 Solvay Pharmaceuticals B.V. Oral sustained release formulation of tedisamil with gastric retention properties
UA86831C2 (en) 2004-08-13 2009-05-25 Бьорінгер Інгельхайм Інтернаціональ Гмбх Extended release tablet formulation comprising pramipexole or pharmaceutically acceptable salt thereof, method for its manufacturing and administration
DE102004042139B4 (en) * 2004-08-31 2009-06-10 Aristocon Verwaltungs- Gmbh Peroral dosage forms to achieve a retarding effect after drug intake with a meal
EP1690540A1 (en) * 2005-02-15 2006-08-16 Neuro3D Composition comprising ocaperidone
EP1962586B1 (en) 2005-12-22 2017-07-12 Oakwood Laboratories L.L.C. Sublimable sustained release delivery system and method of making same
EP1886665A1 (en) * 2006-08-01 2008-02-13 Boehringer Ingelheim Pharma GmbH & Co. KG Gastro retentive delivery system
ES2350029T3 (en) * 2007-03-02 2011-01-17 Farnam Companies, Inc. SUSTAINED RELEASE PELLETS THAT INCLUDE A WAX TYPE MATERIAL.
ES2740360T3 (en) 2008-08-15 2020-02-05 Assertio Therapeutics Inc Pharmaceutical gastric retention compositions for the treatment and prevention of CNS disorders
JP2012500230A (en) 2008-08-18 2012-01-05 北京天衡▲薬▼物研究院 Gastric retention drug release system and method and use thereof
BRPI0914080A2 (en) * 2008-10-08 2015-10-27 Bioplus Life Sciences Pvt Ltda "controlled dosage release system, method of administration and process of preparation thereof"
EP2283824B1 (en) 2009-07-30 2017-04-19 Special Products Line S.p.A. Compositions and formulations based on swellable matrices for sustained release of poorly soluble drugs such as clarithromycin
JP2013103879A (en) * 2011-11-10 2013-05-30 Nakanihon Capsule Co Ltd Hard capsule
KR102241487B1 (en) 2013-02-20 2021-04-16 주식회사 종근당 Pharmaceutical composition consisting of sustained-release pellets
ES2761407T3 (en) * 2013-03-15 2020-05-19 Aprecia Pharmaceuticals LLC Quickly dispersible topiramate dosage form
CN103462917A (en) * 2013-09-12 2013-12-25 南京正宽医药科技有限公司 Antiviral acyclovir tablet and preparation method thereof
RU2749883C2 (en) * 2016-06-14 2021-06-18 Эланко Кэнэда Лимитед Pelleted animal feed containing feed additive, method for its preparation and application
US10588863B2 (en) 2017-06-16 2020-03-17 Kashiv Biosciences, Llc Extended release compositions comprising pyridostigmine
US10918597B2 (en) * 2017-06-16 2021-02-16 Kashiv Specialty Pharmaceuticals, Llc Gastroretentive dosage forms for sustained drug delivery
US10987311B2 (en) 2017-06-16 2021-04-27 Kashiv Specialty Pharmaceuticals, Llc Extended release compositions comprising pyridostigmine
CN107441115A (en) * 2017-08-22 2017-12-08 安徽省肿瘤医院 A kind of purposes of Verapamil joint sodium acid carbonate in primary liver cancer medicine is prepared
CN107349195A (en) * 2017-08-22 2017-11-17 安徽省肿瘤医院 A kind of Verapamil is preparing the purposes in treating metastatic hepatic carcinoma medicine
CN107375287B (en) * 2017-08-22 2019-11-29 安徽省肿瘤医院 A kind of purposes of atropine sulfate in preparation treatment Primary Hepatic cancer drug
DK3824881T3 (en) 2018-06-18 2022-05-09 Amneal Complex Products Res Llc Composition comprising extended release pyridostigmine bromide
EP3970701B1 (en) 2018-06-27 2025-05-07 Amneal Complex Products Research LLC Self-regulating osmotic gastroretentive drug delivery systems
WO2020230089A1 (en) 2019-05-14 2020-11-19 Clexio Biosciences Ltd. Treatment of nocturnal symptoms and morning akinesia in subjects with parkinson's disease
WO2022195476A1 (en) 2021-03-15 2022-09-22 Clexio Biosciences Ltd. Gastroretentive devices for assessment of intragastric conditions

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH675537A5 (en) * 1988-03-25 1990-10-15 Ciba Geigy Ag
US5096714A (en) * 1988-06-28 1992-03-17 Hauser-Kuhrts, Inc. Prolonged release drug tablet formulations
EP0497977B1 (en) * 1989-10-26 1995-03-15 Nippon Shinyaku Company, Limited Gastric preparation
MX9300110A (en) * 1992-01-13 1994-07-29 Gerhard Gergely PHARMACEUTICAL PREPARATION IN THE FORM OF AN EFFERVESCENCE OR DISINTEGRATION TABLET OR OF AN INSTANT-TYPE GRANULATE AND PROCEDURE FOR ITS PREPARATION.
GB9322314D0 (en) * 1993-10-29 1993-12-15 Scherer Ltd R P Foam generating capsules
DE4403943A1 (en) * 1994-02-08 1995-08-10 Hexal Pharma Gmbh Oral preparation of the preparation with diclofenac sodium
GB9418530D0 (en) * 1994-09-14 1994-11-02 Glaxo Group Ltd Medicaments
US5788987A (en) * 1997-01-29 1998-08-04 Poli Industria Chimica Spa Methods for treating early morning pathologies
IT1293764B1 (en) * 1997-07-23 1999-03-10 Chiesi Farma Spa PHARMACEUTICAL COMPOSITIONS IN THE FORM OF EFFERVESCENT TABLETS CONTAINING AN UNSTABLE ACTIVE IN THE PRESENCE OF WATER

Also Published As

Publication number Publication date
AU774957B2 (en) 2004-07-15
EP1206249A1 (en) 2002-05-22
EP1206249A4 (en) 2004-12-22
WO2001010419A1 (en) 2001-02-15
BR0012981A (en) 2002-06-18
ZA200200926B (en) 2002-11-27
NZ516959A (en) 2003-10-31
AU6309900A (en) 2001-03-05
TR200200467T2 (en) 2002-08-21
AP2002002410A0 (en) 2002-03-31
CN1376059A (en) 2002-10-23
HRP20020108A2 (en) 2003-12-31
CA2378468A1 (en) 2001-02-15
AU5060499A (en) 2001-03-05
MXPA02001272A (en) 2002-07-22
HUP0202497A2 (en) 2002-11-28
PL353321A1 (en) 2003-11-17
JP2003506400A (en) 2003-02-18
OA12003A (en) 2006-04-18
HUP0202497A3 (en) 2004-05-28
IL147966A0 (en) 2002-09-12
SK1832002A3 (en) 2002-08-06
HK1047226A1 (en) 2003-02-14
CZ2002415A3 (en) 2002-08-14
WO2001010405A1 (en) 2001-02-15

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