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EA199900438A1 - Препарат местного применения для введения пептидных лекарственных средств в живые организмы - Google Patents

Препарат местного применения для введения пептидных лекарственных средств в живые организмы

Info

Publication number
EA199900438A1
EA199900438A1 EA199900438A EA199900438A EA199900438A1 EA 199900438 A1 EA199900438 A1 EA 199900438A1 EA 199900438 A EA199900438 A EA 199900438A EA 199900438 A EA199900438 A EA 199900438A EA 199900438 A1 EA199900438 A1 EA 199900438A1
Authority
EA
Eurasian Patent Office
Prior art keywords
living organisms
introduction
preparation
local application
peptide
Prior art date
Application number
EA199900438A
Other languages
English (en)
Other versions
EA002023B1 (ru
Inventor
Золтан Дардаи
Original Assignee
Золтан Дардаи
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Золтан Дардаи filed Critical Золтан Дардаи
Publication of EA199900438A1 publication Critical patent/EA199900438A1/ru
Publication of EA002023B1 publication Critical patent/EA002023B1/ru

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/28Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

Настоящее изобретение относится к фармацевтическим препаратам местного применения, благодаря которым возможно введение пептидных лекарственных средств в живые организмы путем трансдермальной резорбции. Эти препараты включают (i) пептидное лекарственное средство, (ii) капсаицин, гистамин и/или экстракт шпанских мушек и (iii) эпителизирующий агент в смеси с наполнителями и/или растворителями, традиционно использующимися в производстве фармацевтических препаратов местного применения, не обязательно нанесенные на подложку, которая может приклеиваться к коже.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA199900438A 1996-12-03 1997-09-08 Фармацевтическая композиция местного применения для введения в живой организм, содержащая пептидное лекарственное средство EA002023B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU9603327A HU223205B1 (hu) 1996-12-03 1996-12-03 Helyileg alkalmazható készítmény peptidszerű gyógyhatású vegyületek élő szervezetbe vitelére
PCT/HU1997/000049 WO1998024470A1 (en) 1996-12-03 1997-09-08 Topical preparation for introducing peptidaceous pharmacons in living organisms

Publications (2)

Publication Number Publication Date
EA199900438A1 true EA199900438A1 (ru) 2000-02-28
EA002023B1 EA002023B1 (ru) 2001-12-24

Family

ID=89994502

Family Applications (1)

Application Number Title Priority Date Filing Date
EA199900438A EA002023B1 (ru) 1996-12-03 1997-09-08 Фармацевтическая композиция местного применения для введения в живой организм, содержащая пептидное лекарственное средство

Country Status (24)

Country Link
US (1) US6399566B1 (ru)
EP (1) EP0942743B1 (ru)
JP (1) JP2001505222A (ru)
KR (1) KR100466757B1 (ru)
CN (1) CN1239436A (ru)
AP (1) AP1065A (ru)
AT (1) ATE213954T1 (ru)
AU (1) AU744380B2 (ru)
BR (1) BR9714945A (ru)
CA (1) CA2272604A1 (ru)
CZ (1) CZ289788B6 (ru)
DE (1) DE69710918T2 (ru)
DK (1) DK0942743T3 (ru)
EA (1) EA002023B1 (ru)
ES (1) ES2174291T3 (ru)
HU (1) HU223205B1 (ru)
IL (1) IL129915A0 (ru)
IS (1) IS5052A (ru)
NO (1) NO992668L (ru)
NZ (1) NZ336045A (ru)
OA (1) OA11180A (ru)
SK (1) SK284306B6 (ru)
TR (1) TR199901232T2 (ru)
WO (1) WO1998024470A1 (ru)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU225734B1 (en) * 1999-07-28 2007-07-30 Zoltan Dardai Multilayer plaster for introducing peptidaceous pharmacons in living organisms and process for producing thereof
AU6751000A (en) * 1999-07-30 2001-02-19 Maxim Pharmaceuticals, Inc. Use of histamine as a drug delivery enhancing compound for use in transmucosal or transdermal delivery
US7176278B2 (en) 2001-08-30 2007-02-13 Biorexis Technology, Inc. Modified transferrin fusion proteins
WO2004069180A2 (en) 2003-01-31 2004-08-19 Smithkline Beecham Corporation Solid dispersion compositions
US8637096B2 (en) 2009-12-04 2014-01-28 Curtis C. Stojan Compositions and method for enhancing insulin activity
KR101457263B1 (ko) * 2012-02-03 2014-11-07 단국대학교 산학협력단 파스의 제조방법

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3009143A1 (de) * 1980-03-10 1981-10-01 Hans Dr Bauersfeld Arzneimittelzubereitung und deren verwendung
JPS5879913A (ja) * 1981-11-09 1983-05-13 Taizo Ayukawa ヘアトニツク組成物
WO1991015117A1 (en) * 1990-04-05 1991-10-17 Basic Bio Systems, Inc. Film-forming proteinaceous emulsion
CH687053A5 (fr) * 1993-10-05 1996-09-13 Crina Additifs pour l'alimentation animale et procédé pour leur préparation.
US5686100A (en) * 1994-11-22 1997-11-11 E.R. Squibb & Sons, Inc. Prophylactic and therapeutic treatment of skin sensitization and irritation
AUPN089295A0 (en) * 1995-02-02 1995-03-02 International Diabetes Institute Treatment of diabetic neuropathy

Also Published As

Publication number Publication date
NO992668D0 (no) 1999-06-02
WO1998024470A1 (en) 1998-06-11
IL129915A0 (en) 2000-02-29
DK0942743T3 (da) 2002-06-10
DE69710918D1 (de) 2002-04-11
EP0942743B1 (en) 2002-03-06
TR199901232T2 (xx) 1999-08-23
ATE213954T1 (de) 2002-03-15
CZ192099A3 (cs) 1999-09-15
CN1239436A (zh) 1999-12-22
KR20000057371A (ko) 2000-09-15
US6399566B1 (en) 2002-06-04
HU223205B1 (hu) 2004-03-29
HUP9603327A2 (hu) 1998-10-28
AP1065A (en) 2002-04-30
EA002023B1 (ru) 2001-12-24
SK68799A3 (en) 2000-02-14
HU9603327D0 (en) 1997-01-28
KR100466757B1 (ko) 2005-01-24
ES2174291T3 (es) 2002-11-01
DE69710918T2 (de) 2002-10-24
EP0942743A1 (en) 1999-09-22
HUP9603327A3 (en) 1998-11-30
CZ289788B6 (cs) 2002-04-17
AU4468897A (en) 1998-06-29
NZ336045A (en) 2000-10-27
IS5052A (is) 1999-05-18
OA11180A (en) 2003-05-12
JP2001505222A (ja) 2001-04-17
BR9714945A (pt) 2002-02-13
NO992668L (no) 1999-06-02
CA2272604A1 (en) 1998-06-11
AU744380B2 (en) 2002-02-21
SK284306B6 (sk) 2005-01-03
AP9901554A0 (en) 1999-06-30

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Legal Events

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MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ KZ KG MD TJ TM

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): BY

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): RU