DK508484D0 - N-substituerede isoquinolinderivater og farmaceutisk praeparat indeholdende dem - Google Patents
N-substituerede isoquinolinderivater og farmaceutisk praeparat indeholdende demInfo
- Publication number
- DK508484D0 DK508484D0 DK508484A DK508484A DK508484D0 DK 508484 D0 DK508484 D0 DK 508484D0 DK 508484 A DK508484 A DK 508484A DK 508484 A DK508484 A DK 508484A DK 508484 D0 DK508484 D0 DK 508484D0
- Authority
- DK
- Denmark
- Prior art keywords
- alkyl
- carbon atoms
- phenyl
- alkoxy
- isoquinoline derivatives
- Prior art date
Links
- -1 N-SUBSTITUTED ISOQUINOLINE Chemical class 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 8
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
- C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Transplantation (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU833652A HU189765B (en) | 1983-10-25 | 1983-10-25 | Process for preparing n-substituted 1-(bis (hydroxy-metiol)-methyl)-isoquinoline-derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK508484D0 true DK508484D0 (da) | 1984-10-25 |
| DK508484A DK508484A (da) | 1985-04-26 |
Family
ID=10964925
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK508484A DK508484A (da) | 1983-10-25 | 1984-10-25 | N-substituerede isoquinolinderivater og farmaceutisk praeparat indeholdende dem |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4668688A (da) |
| EP (1) | EP0142740B1 (da) |
| JP (1) | JPS60132962A (da) |
| AT (1) | ATE35133T1 (da) |
| CA (1) | CA1265141A (da) |
| DE (1) | DE3472104D1 (da) |
| DK (1) | DK508484A (da) |
| FI (1) | FI79533C (da) |
| HU (1) | HU189765B (da) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4902695A (en) * | 1989-02-13 | 1990-02-20 | Eli Lilly And Company | Excitatory amino acid receptor antagonists |
| US5360569A (en) * | 1993-11-12 | 1994-11-01 | Lever Brothers Company, Division Of Conopco, Inc. | Activation of bleach precursors with catalytic imine quaternary salts |
| US5360568A (en) * | 1993-11-12 | 1994-11-01 | Lever Brothers Company, Division Of Conopco, Inc. | Imine quaternary salts as bleach catalysts |
| EP0728182B1 (en) * | 1993-11-12 | 1997-09-03 | Unilever N.V. | Imine salts as bleach catalysts |
| US8034815B2 (en) | 2007-01-11 | 2011-10-11 | Critical Outcome Technologies, Inc. | Compounds and method for treatment of cancer |
| CA2710039C (en) | 2007-12-26 | 2018-07-03 | Critical Outcome Technologies, Inc. | Semicarbazones, thiosemicarbazones and related compounds and methods for treatment of cancer |
| WO2010006438A1 (en) | 2008-07-17 | 2010-01-21 | Critical Outcome Technologies Inc. | Thiosemicarbazone inhibitor compounds and cancer treatment methods |
| US8987272B2 (en) | 2010-04-01 | 2015-03-24 | Critical Outcome Technologies Inc. | Compounds and method for treatment of HIV |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1199775B (de) * | 1960-04-01 | 1965-09-02 | Hoffmann La Roche | Verfahren zur Herstellung von analgetisch, hustenlindernd und spasmolytisch wirksamenTetrahydroisochinolinderivaten |
| US3562280A (en) * | 1967-08-30 | 1971-02-09 | Hoffmann La Roche | Substituted 1,2,3,4-tetrahydroisoquinolines |
| DD121321A1 (da) * | 1975-04-24 | 1976-07-20 | ||
| HU178454B (en) * | 1979-07-02 | 1982-05-28 | Chinoin Gyogyszer Es Vegyeszet | Process for preparing new isoquinoline derivatives containing sulphur |
-
1983
- 1983-10-25 HU HU833652A patent/HU189765B/hu not_active IP Right Cessation
-
1984
- 1984-10-25 CA CA000466329A patent/CA1265141A/en not_active Expired - Lifetime
- 1984-10-25 FI FI844185A patent/FI79533C/fi not_active IP Right Cessation
- 1984-10-25 DK DK508484A patent/DK508484A/da not_active Application Discontinuation
- 1984-10-25 AT AT84112855T patent/ATE35133T1/de not_active IP Right Cessation
- 1984-10-25 US US06/664,770 patent/US4668688A/en not_active Expired - Fee Related
- 1984-10-25 DE DE8484112855T patent/DE3472104D1/de not_active Expired
- 1984-10-25 EP EP84112855A patent/EP0142740B1/en not_active Expired
- 1984-10-25 JP JP59223091A patent/JPS60132962A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US4668688A (en) | 1987-05-26 |
| FI79533B (fi) | 1989-09-29 |
| HU189765B (en) | 1986-07-28 |
| DE3472104D1 (en) | 1988-07-21 |
| FI79533C (fi) | 1990-01-10 |
| CA1265141A (en) | 1990-01-30 |
| EP0142740A1 (en) | 1985-05-29 |
| ATE35133T1 (de) | 1988-07-15 |
| DK508484A (da) | 1985-04-26 |
| EP0142740B1 (en) | 1988-06-15 |
| FI844185A0 (fi) | 1984-10-25 |
| FI844185L (fi) | 1985-04-26 |
| JPS60132962A (ja) | 1985-07-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHB | Application shelved due to non-payment |