[go: up one dir, main page]

DK479487D0 - (1h-imidazol-1-ylmethyl)-substituerede benzimidazol-derivater - Google Patents

(1h-imidazol-1-ylmethyl)-substituerede benzimidazol-derivater

Info

Publication number
DK479487D0
DK479487D0 DK479487A DK479487A DK479487D0 DK 479487 D0 DK479487 D0 DK 479487D0 DK 479487 A DK479487 A DK 479487A DK 479487 A DK479487 A DK 479487A DK 479487 D0 DK479487 D0 DK 479487D0
Authority
DK
Denmark
Prior art keywords
imidazol
ylmethyl
benzimidazole derivatives
substituted benzimidazole
substituted
Prior art date
Application number
DK479487A
Other languages
English (en)
Other versions
DK174728B1 (da
DK479487A (da
Inventor
Alfons Herman Marg Raeymaekers
Eddy Jean Edgard Freyne
Gerard Charles Sanz
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of DK479487D0 publication Critical patent/DK479487D0/da
Publication of DK479487A publication Critical patent/DK479487A/da
Application granted granted Critical
Publication of DK174728B1 publication Critical patent/DK174728B1/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/06Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK198704794A 1986-09-15 1987-09-14 (1H-imidazol-1-ylmethyl)-substituerede benzimidazolderivater, fremgangsmåde til fremstilling deraf, farmaceutiske præparater indeholdende derivaterne og anvendelse af derivaterne til fremstilling af lægemidler DK174728B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US90790386A 1986-09-15 1986-09-15
US90790386 1986-09-15

Publications (3)

Publication Number Publication Date
DK479487D0 true DK479487D0 (da) 1987-09-14
DK479487A DK479487A (da) 1988-03-16
DK174728B1 DK174728B1 (da) 2003-10-06

Family

ID=25424835

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198704794A DK174728B1 (da) 1986-09-15 1987-09-14 (1H-imidazol-1-ylmethyl)-substituerede benzimidazolderivater, fremgangsmåde til fremstilling deraf, farmaceutiske præparater indeholdende derivaterne og anvendelse af derivaterne til fremstilling af lægemidler

Country Status (23)

Country Link
EP (1) EP0260744B1 (da)
JP (1) JPS6485975A (da)
KR (1) KR960014353B1 (da)
CN (1) CN1020903C (da)
AU (1) AU595064B2 (da)
BG (1) BG61321B2 (da)
CA (1) CA1323366C (da)
CY (1) CY1803A (da)
DE (1) DE3783107T2 (da)
DK (1) DK174728B1 (da)
ES (1) ES2053524T3 (da)
FI (1) FI87781C (da)
GR (1) GR3006841T3 (da)
HK (1) HK123694A (da)
HU (1) HU198039B (da)
IE (1) IE60514B1 (da)
IL (1) IL83892A (da)
NO (1) NO167202C (da)
NZ (1) NZ221729A (da)
PH (1) PH25022A (da)
PT (1) PT85692B (da)
SU (1) SU1662350A3 (da)
ZA (1) ZA876881B (da)

Families Citing this family (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4826862A (en) * 1988-02-12 1989-05-02 Janssen Pharmaceutica, N.V. Anthelminthic [(5(6) (1H-azole-1-ylmethyl)benzimidazole]carbamates
CA2002859C (en) * 1988-11-29 1998-12-29 Jean P. F. Van Wauwe Method of treating epithelial disorders
CA2002864C (en) * 1988-11-29 1999-11-16 Eddy J. E. Freyne (1h-azol-1-ylmethyl) substituted quinoline, quinazoline or quinoxaline derivatives
GB8827820D0 (en) * 1988-11-29 1988-12-29 Janssen Pharmaceutica Nv (1h-azol-1-ylmethyl)substituted quinoline derivatives
FR2643903A1 (fr) * 1989-03-03 1990-09-07 Union Pharma Scient Appl Nouveaux derives de benzimidazole, leurs procedes de preparation, intermediaires de synthese, compositions pharmaceutiques les contenant, utiles notamment pour le traitement des maladies cardiovasculaires, et des ulceres duodenaux
PT95899A (pt) * 1989-11-17 1991-09-13 Glaxo Group Ltd Processo para a preparacao de derivados indole
US5021448A (en) * 1990-02-22 1991-06-04 Ciba-Geigy Corporation Method of reducing serum uric acid and/or increasing renal uric acid clearance with thromboxane synthetase inhibitor inhibitor and/or thromboxane receptor antagonist
FR2663028B1 (fr) * 1990-06-08 1994-10-14 Roussel Uclaf Nouveaux derives de benzimidazole, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant.
US5216003A (en) * 1992-01-02 1993-06-01 G. D. Searle & Co. Diacid-containing benzimidazole compounds for treatment of neurotoxic injury
WO1995004723A1 (en) * 1993-08-04 1995-02-16 Yamanouchi Pharmaceutical Co., Ltd. Imidazolylalkylamine derivative and pharmaceutical composition thereof
FI961418L (fi) * 1993-09-30 1996-03-29 Yamanouchi Pharma Co Ltd Atsolijohdannainen ja sen farmaseuttinen seos
SG47122A1 (en) * 1994-02-18 1998-03-20 Janssen Pharmaceutica Nv Enantiomerically pure(-)-liarozole
WO1995022540A1 (en) * 1994-02-18 1995-08-24 Janssen Pharmaceutica N.V. Enantiomerically pure (+)-liarozole
GB9418443D0 (en) * 1994-09-13 1994-11-02 Pfizer Ltd Therapeutic agents
DE69531998T2 (de) * 1994-12-22 2004-07-22 Ligand Pharmaceuticals, Inc., San Diego Steroidrezeptor-modulator verbindungen und methoden
US6696459B1 (en) 1994-12-22 2004-02-24 Ligand Pharmaceuticals Inc. Steroid receptor modulator compounds and methods
US5688808A (en) * 1994-12-22 1997-11-18 Ligand Pharmaceuticals Incorporated Steroid receptor modulator compounds and methods
TW316902B (da) * 1994-12-28 1997-10-01 Janssen Pharmaceutica Nv
PL322028A1 (en) * 1995-03-01 1998-01-05 Yamanouchi Pharma Co Ltd Derivatives of imidazoles and pharmaceutic composition containing them
US6288100B1 (en) * 1995-06-06 2001-09-11 American Home Products Corporation Benzimidazole derivatives
DE19535500A1 (de) * 1995-09-25 1997-03-27 Bayer Ag Verfahren zur Herstellung von 3-Chlor-3'-nitro-4'-methoxybenzophenon
ATE303365T1 (de) * 1995-12-28 2005-09-15 Fujisawa Pharmaceutical Co Benzimidazolderivate
CZ297769B6 (cs) 1996-06-27 2007-03-28 Janssen Pharmaceutica N. V. N-[4-(heteroarylmetyl)fenyl]-heteroarylaminy, zpusob jejich prípravy a jejich pouzití jako léciva
FR2751649B1 (fr) * 1996-07-26 1998-08-28 Adir Nouveaux derives de benzimidazole, de benzoxazole et de benzothiazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
IT1286866B1 (it) * 1996-10-28 1998-07-17 Menarini Farma Ind Composti furano-eterociclici,loro preparazione ed uso come inibitori di aromatasi
AU730369B2 (en) * 1996-11-25 2001-03-08 Board Of Regents Of The University Of Nebraska, The Guanidinyl heterocycle compounds useful as alpha-2 adrenoceptor agonists
ATE231128T1 (de) 1997-02-21 2003-02-15 Takeda Chemical Industries Ltd Verbindungen mit kondensierten ringen, verfahren zu ihrer herstellung und ihre anwendung
TW453999B (en) 1997-06-27 2001-09-11 Fujisawa Pharmaceutical Co Benzimidazole derivatives
DE69824885T2 (de) 1997-12-11 2005-07-21 Janssen Pharmaceutica N.V. Anilide als vitamin-a-säure-mimetika
DE19831985A1 (de) 1998-07-16 2000-01-20 Bayer Ag Substituierte Benzimidazole, ihre Herstellung und ihre Verwendung als Mittel gegen parasitäre Protozoen
US6858598B1 (en) 1998-12-23 2005-02-22 G. D. Searle & Co. Method of using a matrix metalloproteinase inhibitor and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
US6833373B1 (en) 1998-12-23 2004-12-21 G.D. Searle & Co. Method of using an integrin antagonist and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
EP1189889B1 (en) * 1999-06-04 2003-12-17 Elan Pharma International Limited Compositions and methods for inhibiting cell death
YU68102A (sh) 2000-03-16 2006-01-16 F. Hoffmann-La Roche Ag. Derivati karboksilne kiseline kao ip antagonisti
EP1681290B9 (en) 2000-11-17 2013-06-19 Takeda Pharmaceutical Company Limited Imidazole derivatives, production method thereof and use thereof
US6960586B2 (en) 2000-11-20 2005-11-01 Takeda Pharmaceutical Company Limited Imidazole derivatives, process for their preparation and their use
DE60139639D1 (de) 2000-12-08 2009-10-01 Takeda Pharmaceutical Substituierte thiazolderivate mit 3-pyridylgruppen, verfahren zu deren herstellung und deren verwendung
US7405235B2 (en) 2001-05-04 2008-07-29 Paratek Pharmaceuticals, Inc. Transcription factor modulating compounds and methods of use thereof
US6492517B1 (en) 2001-07-19 2002-12-10 Air Products And Chemicals, Inc. Method for preparing halomethyl heterocyclic compounds
CN101092400A (zh) * 2001-11-16 2007-12-26 日本化学医药株式会社 黄嘌呤氧化酶抑制剂
JP2006513162A (ja) * 2002-11-01 2006-04-20 パラテック ファーマシューティカルズ インコーポレイテッド 転写因子調節化合物およびその使用方法
JP2007500245A (ja) * 2003-06-10 2007-01-11 スミスクライン ビーチャム コーポレーション 化合物
FR2860235A1 (fr) * 2003-09-29 2005-04-01 Yang Ji Chemical Company Ltd Utilisation d'un compose de formule (i) inhibiteur de l'aromatase a des fins therapeutiques et composes de formule (i) en tant que tels
US20060160799A1 (en) 2004-04-23 2006-07-20 Alekshun Michael N Transcription factor modulating compounds and methods of use thereof
US7566733B2 (en) 2004-09-30 2009-07-28 Janssen Pharmaceutica N.V. Benzimidazole derivatives useful as selective androgen receptor modulators (sarms)
JP4953455B2 (ja) * 2004-09-30 2012-06-13 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 選択的アンドロゲン受容体モジュレーター(sarm)として有用な新規なベンゾイミダゾール誘導体
EA015542B1 (ru) * 2006-01-24 2011-08-30 Янссен Фармацевтика Н.В. Новые 2-замещённые бензимидазолы в качестве селективных модуляторов рецептора андрогена (sarms)
JP5188988B2 (ja) 2006-02-10 2013-04-24 トランステック ファーマ,インコーポレイティド ベンゾアゾール誘導体、組成物、及びオーロラキナーゼ阻害剤としての使用方法
KR101307497B1 (ko) * 2006-04-19 2013-09-11 주식회사 동진쎄미켐 디이미다졸계 화합물 및 이를 이용한 유기발광소자
CN100496308C (zh) * 2006-06-02 2009-06-10 上海烟草(集团)公司 造纸法再造烟叶半逆流多级萃取工艺
EP1992228A1 (en) * 2007-05-14 2008-11-19 Bayer CropScience AG Insecticidal substituted thiourea derivatives
BRPI0811783A2 (pt) * 2007-05-23 2014-11-11 Allergan Inc Compostos de ((heteroarila bicíclica)imidazolil)metil-heteroarila como agonistas dos receptores adrenérgicos.
DE102009038950A1 (de) 2009-08-26 2011-03-03 Bayer Animal Health Gmbh Neue antiparasitäre Kombination von Wirkstoffen
JP2013540145A (ja) * 2010-10-21 2013-10-31 ウニベルシテート デス ザールランデス コルチゾール依存性疾患の治療用の選択的cyp11b1阻害剤
US9199975B2 (en) 2011-09-30 2015-12-01 Asana Biosciences, Llc Biaryl imidazole derivatives for regulating CYP17
CA2850508A1 (en) * 2011-09-30 2013-04-04 Endo Pharmaceuticals Inc. Imidazole derivatives as cyp17 inhibitors for the treatment of cancer
KR101884447B1 (ko) * 2015-07-06 2018-08-01 삼성에스디아이 주식회사 모노머, 유기막 조성물, 유기막, 및 패턴형성방법
CN118265545A (zh) * 2021-10-04 2024-06-28 博尔特生物治疗药物有限公司 不对称双苯并咪唑sting激动剂免疫缀合物及其用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR75101B (da) * 1980-10-23 1984-07-13 Pfizer
GB8307865D0 (en) * 1983-03-22 1983-04-27 Fujisawa Pharmaceutical Co Benzimidazole derivatives
EP0178413A1 (en) * 1984-08-17 1986-04-23 Beecham Group Plc Benzimidazoles

Also Published As

Publication number Publication date
PT85692A (en) 1987-10-01
KR880003935A (ko) 1988-06-01
HK123694A (en) 1994-11-18
FI87781C (fi) 1993-02-25
JPH0587071B2 (da) 1993-12-15
FI873977A7 (fi) 1988-03-16
ES2053524T3 (es) 1994-08-01
CN87106423A (zh) 1988-04-20
IL83892A0 (en) 1988-02-29
ZA876881B (en) 1989-04-26
DK174728B1 (da) 2003-10-06
NO167202C (no) 1991-10-16
EP0260744A3 (en) 1989-01-18
PH25022A (en) 1991-01-28
JPS6485975A (en) 1989-03-30
PT85692B (pt) 1990-06-29
NZ221729A (en) 1989-07-27
DK479487A (da) 1988-03-16
CN1020903C (zh) 1993-05-26
GR3006841T3 (da) 1993-06-30
HUT45051A (en) 1988-05-30
HU198039B (en) 1989-07-28
FI87781B (fi) 1992-11-13
AU7838587A (en) 1988-04-14
NO873840L (no) 1988-03-16
EP0260744A2 (en) 1988-03-23
KR960014353B1 (ko) 1996-10-15
FI873977A0 (fi) 1987-09-14
BG61321B2 (bg) 1997-05-30
CY1803A (en) 1987-09-09
IL83892A (en) 1991-11-21
EP0260744B1 (en) 1992-12-16
DE3783107T2 (de) 1993-04-22
AU595064B2 (en) 1990-03-22
CA1323366C (en) 1993-10-19
IE60514B1 (en) 1994-07-27
NO167202B (no) 1991-07-08
NO873840D0 (no) 1987-09-14
DE3783107D1 (de) 1993-01-28
SU1662350A3 (ru) 1991-07-07
IE872487L (en) 1988-03-15

Similar Documents

Publication Publication Date Title
DK479487D0 (da) (1h-imidazol-1-ylmethyl)-substituerede benzimidazol-derivater
FI913963A7 (fi) Uudet bentsimidatsolijohdannaiset
DK425887A (da) Imidazolderivater
DE3781845D1 (de) Benzimidazol-derivate.
DE3768992D1 (de) Benzimidazol-derivate.
DK483689A (da) Imidazolderivater
DK64089D0 (da) ((5(6)-(1h-azol-1-ylmethyl)benzimidazol) carbamater
DK138488D0 (da) Imidazolderivater
DK337086D0 (da) Benzimidazolderivater
DK218887A (da) Imidazoliumsalte
DK392889D0 (da) Imidazolderivater
DK569786D0 (da) Benzimidazolderivater
DK405988A (da) Benzimidazolderivater
DK445087D0 (da) 5-substituerede-3-phenyl-3-(1h-imidazol-1-ylmethyl)-2-methylisoxazolidiner
DK506787A (da) Imidazoliumsalte
DK364187D0 (da) Imidazolderivater
FI903967A7 (fi) Uusia imidatsolijohdannaisia
DK631287D0 (da) Azolderivater
DK375887D0 (da) Imidazolderivater
BR1101052A (pt) Derivados de benzimidazol (1h-imidazol-1-ilmetil)-substituìdos
LV5770A4 (lv) (1H-imidazol-1-ilmetil)aizvietota benzimidazola atvasinajumi
DK569686A (da) Benzimidazolderivater
SG118994G (en) (1H-imidazol-1-ylmethyl) substituted benzimidazole derivatives
LV5267A3 (lv) Panemiens imidazola atvasinajumu iegusanai
KR880012850U (ko) 언어발성 제어식 건조기

Legal Events

Date Code Title Description
PUP Patent expired