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DK3988138T3 - Flerlaget kunstig hjertemuskel - Google Patents

Flerlaget kunstig hjertemuskel Download PDF

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Publication number
DK3988138T3
DK3988138T3 DK20203316.3T DK20203316T DK3988138T3 DK 3988138 T3 DK3988138 T3 DK 3988138T3 DK 20203316 T DK20203316 T DK 20203316T DK 3988138 T3 DK3988138 T3 DK 3988138T3
Authority
DK
Denmark
Prior art keywords
heart muscle
artificial heart
multilayered artificial
multilayered
muscle
Prior art date
Application number
DK20203316.3T
Other languages
English (en)
Inventor
Wolfram-Hubertus Zimmermann
Malte Tiburcy
Tim Meyer
Original Assignee
Georg August Univ Goettingen Stiftung Oeffentlichen Rechts Univsmedizin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Georg August Univ Goettingen Stiftung Oeffentlichen Rechts Univsmedizin filed Critical Georg August Univ Goettingen Stiftung Oeffentlichen Rechts Univsmedizin
Application granted granted Critical
Publication of DK3988138T3 publication Critical patent/DK3988138T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3895—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3826—Muscle cells, e.g. smooth muscle cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3886—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells comprising two or more cell types
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/20—Materials or treatment for tissue regeneration for reconstruction of the heart, e.g. heart valves

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Cell Biology (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Dispersion Chemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)
DK20203316.3T 2020-10-22 2020-10-22 Flerlaget kunstig hjertemuskel DK3988138T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP20203316.3A EP3988138B1 (en) 2020-10-22 2020-10-22 Multilayer engineered heart muscle

Publications (1)

Publication Number Publication Date
DK3988138T3 true DK3988138T3 (da) 2024-02-26

Family

ID=73013233

Family Applications (1)

Application Number Title Priority Date Filing Date
DK20203316.3T DK3988138T3 (da) 2020-10-22 2020-10-22 Flerlaget kunstig hjertemuskel

Country Status (11)

Country Link
US (1) US20230390460A1 (da)
EP (1) EP3988138B1 (da)
JP (1) JP2023546466A (da)
KR (1) KR20230093270A (da)
CN (1) CN116801922A (da)
AU (1) AU2021363610A1 (da)
CA (1) CA3195739A1 (da)
DK (1) DK3988138T3 (da)
ES (1) ES2972851T3 (da)
IL (1) IL302287A (da)
WO (1) WO2022084429A1 (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4029537A1 (en) * 2021-01-19 2022-07-20 Universitätsklinikum Hamburg-Eppendorf Engineered heart tissue patch, apparatus and method for producing the same
DE102024113398A1 (de) 2024-05-14 2025-11-20 Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin Herstellung von künstlichem Skelettmuskel in einem Bioreaktor

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4738740A (en) * 1985-11-21 1988-04-19 Corvita Corporation Method of forming implantable vascular grafts
BR0013639A (pt) * 1999-08-31 2004-06-15 Univ Virginia Commonwealth Matriz extra celular, processo para a manufatura de uma matriz extracelular, processo para formar uma prótese vascular, implante muscular, matriz extracelular para suporte de músculo, processo de formação de um revestimento facial muscular e processo de sobreposição de camadas de céluas musculares em uma matriz extracelular
EP1783206A1 (en) 2005-11-08 2007-05-09 Universitätsklinikum Hamburg-Eppendorf Multiring engineered heart tissue construct
EP1920789A1 (en) 2006-11-11 2008-05-14 Universitätsklinikum Hamburg-Eppendorf Pouch-like construct comprising mammalian tissue
JP2011130995A (ja) * 2009-12-25 2011-07-07 Japan Health Science Foundation 管腔構造体及び管腔構造体の製造方法
US9289454B2 (en) * 2010-09-14 2016-03-22 Tokyo Women's Medical University Method for manufacturing multilayered cell sheet, multilayered cell sheet having vascular network obtained thereby, and method of use thereof
WO2014186430A1 (en) * 2013-05-16 2014-11-20 Trustees Of Boston University Multi-layered cell constructs and methods of use and production using enzymatically degradable natural polymers
ES2615396T3 (es) 2013-08-22 2017-06-07 Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts Universitätsmedizin Método para producir músculo cardiaco por ingeniería (EHM)
DK2842581T3 (da) * 2013-08-30 2019-02-18 Georg August Univ Goettingen Stiftung Oeffentlichen Rechts Univsmedizin Sæklignende struktur med parakrinaktivitet og fremgangsmåde til fremstilling deraf
SG11201601798RA (en) 2013-09-20 2016-04-28 Repairon Gmbh A method to direct differentiation of pluripotent stem cells into functional heart muscle
CN105749350B (zh) * 2016-04-21 2019-05-21 四川大学 一种心肌补片及其制备方法
DE102016110328B3 (de) 2016-06-03 2017-09-07 Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin Lochplatte
CN109793934B (zh) * 2017-11-17 2021-06-29 中国科学院大连化学物理研究所 一种组织工程化心肌补片及其制备和应用
EP3820993A1 (en) * 2018-07-13 2021-05-19 Lothar Germeroth Non-immunogenic engineered tissue and methods of producing and using the same
JP2020054256A (ja) * 2018-09-28 2020-04-09 国立大学法人大阪大学 多層心筋組織培養物の製造方法

Also Published As

Publication number Publication date
JP2023546466A (ja) 2023-11-02
CA3195739A1 (en) 2022-04-28
CN116801922A (zh) 2023-09-22
EP3988138A1 (en) 2022-04-27
EP3988138A8 (en) 2022-09-07
IL302287A (en) 2023-06-01
ES2972851T3 (es) 2024-06-17
WO2022084429A1 (en) 2022-04-28
AU2021363610A1 (en) 2023-05-18
US20230390460A1 (en) 2023-12-07
EP3988138B1 (en) 2024-01-17
KR20230093270A (ko) 2023-06-27

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