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DK3810633T3 - Forbindelser - Google Patents

Forbindelser Download PDF

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Publication number
DK3810633T3
DK3810633T3 DK19734346.0T DK19734346T DK3810633T3 DK 3810633 T3 DK3810633 T3 DK 3810633T3 DK 19734346 T DK19734346 T DK 19734346T DK 3810633 T3 DK3810633 T3 DK 3810633T3
Authority
DK
Denmark
Prior art keywords
connections
Prior art date
Application number
DK19734346.0T
Other languages
English (en)
Inventor
Pamela Brown
Michael Dawson
Mona Simonovic
Steven Boakes
Esther Duperchy
Dean Rivers
Roy Lester
Scott Coleman
Original Assignee
Spero Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spero Therapeutics Inc filed Critical Spero Therapeutics Inc
Application granted granted Critical
Publication of DK3810633T3 publication Critical patent/DK3810633T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/60—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation occurring through the 4-amino group of 2,4-diamino-butanoic acid
    • C07K7/62—Polymyxins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK19734346.0T 2018-06-25 2019-06-25 Forbindelser DK3810633T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862689602P 2018-06-25 2018-06-25
PCT/EP2019/066819 WO2020002325A1 (en) 2018-06-25 2019-06-25 Compounds

Publications (1)

Publication Number Publication Date
DK3810633T3 true DK3810633T3 (da) 2024-01-15

Family

ID=67107423

Family Applications (1)

Application Number Title Priority Date Filing Date
DK19734346.0T DK3810633T3 (da) 2018-06-25 2019-06-25 Forbindelser

Country Status (31)

Country Link
US (2) US11459357B2 (da)
EP (2) EP4316504A3 (da)
JP (2) JP7488774B2 (da)
KR (1) KR20210054500A (da)
CN (2) CN112789287B (da)
AR (1) AR116663A1 (da)
AU (2) AU2019294261B2 (da)
BR (1) BR112020026663A2 (da)
CA (1) CA3103158A1 (da)
CO (1) CO2020016080A2 (da)
DK (1) DK3810633T3 (da)
EA (1) EA202092819A1 (da)
ES (1) ES2971732T3 (da)
FI (1) FI3810633T3 (da)
HR (1) HRP20240028T1 (da)
HU (1) HUE065134T2 (da)
IL (2) IL279620B1 (da)
LT (1) LT3810633T (da)
MA (1) MA52946B1 (da)
MD (1) MD3810633T2 (da)
MX (1) MX2020013811A (da)
PH (1) PH12020552240A1 (da)
PL (1) PL3810633T3 (da)
PT (1) PT3810633T (da)
RS (1) RS65128B1 (da)
SG (1) SG11202012747VA (da)
SI (1) SI3810633T1 (da)
TW (2) TWI851584B (da)
UA (1) UA128162C2 (da)
WO (1) WO2020002325A1 (da)
ZA (1) ZA202301937B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2015352440B2 (en) 2014-11-26 2020-02-06 Spero Therapeutics, Inc. Compounds
EA202092819A1 (ru) * 2018-06-25 2021-05-21 Сперо Терапьютикс, Инк. Соединения
TW202233649A (zh) 2020-11-06 2022-09-01 美商斯佩羅治療學股份有限公司 化合物
WO2022262823A1 (zh) * 2021-06-18 2022-12-22 华南理工大学 活性氧自由基响应的多粘菌素前药化合物及其应用
CN120518715B (zh) * 2025-07-24 2025-10-03 中国药科大学 一种抗菌肽、药物组合物及应用
CN120699105B (zh) * 2025-08-19 2025-11-21 中国药科大学 一种氘代抗菌肽及其组合物和应用

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2128617A (en) 1982-10-06 1984-05-02 Martti Vaara Polypeptides for use in antibacterial therapy
AU7753787A (en) 1986-08-06 1988-02-24 Jean-Luc Fauchere Production of covalent-linked conjugates from an antibiotic and a non-toxic derivative of polymyxine b
US20010021697A1 (en) 1987-09-14 2001-09-13 Henning Lowenstein Methods and compositions for the treatment of mammalian infections employing medicaments comprising hymenoptera venom, proteinageous or polypeptide components thereof, or analogues of such proteinaceous or polypeptide components
TW274552B (da) 1992-05-26 1996-04-21 Hoechst Ag
US5767068A (en) 1997-02-13 1998-06-16 Pathogenesis Corporation Pure biologically active colistin, its components and a colistin formulation for treatment of pulmonary infections
MXPA06003573A (es) 2003-09-30 2006-08-31 Kohi Corp Composiciones y metodos para tratar quemaduras.
US20060004185A1 (en) 2004-07-01 2006-01-05 Leese Richard A Peptide antibiotics and peptide intermediates for their prepartion
EP3078672A1 (en) 2006-08-11 2016-10-12 Northern Antibiotics Oy Polymyxin derivatives and uses thereof
US7807637B2 (en) 2006-08-11 2010-10-05 Northern Antibiotics Oy Polymyxin derivatives and uses thereof
FI20085469A0 (fi) 2008-02-08 2008-05-16 Northern Antibiotics Oy Polymyksiinijohdannaiset, joissa on lyhyt rasvahappohäntä, ja niiden käyttöjä
US8193148B2 (en) 2008-02-08 2012-06-05 Northern Antibiotics Ltd. Short fatty acid tail polymyxin derivatives and uses thereof
US8329645B2 (en) 2008-02-08 2012-12-11 Northern Antibiotics Ltd. Polymyxin derivatives and uses thereof
ES2334547B1 (es) 2008-09-10 2010-12-03 Universidad De Barcelona Compuestos peptidicos antibacterianos.
AR074874A1 (es) 2008-12-23 2011-02-16 Biosource Pharm Inc Composiciones antibioticas para el tratamiento de infecciones gram negativas. metodo. uso. compuesto.
CN101851270A (zh) 2009-04-03 2010-10-06 梁浩 一种多粘菌素衍生物及其制备方法
WO2010130007A1 (en) 2009-05-14 2010-11-18 Monash University Antimicrobial compounds
US8415307B1 (en) 2010-06-23 2013-04-09 Biosource Pharm, Inc. Antibiotic compositions for the treatment of gram negative infections
WO2012051663A1 (en) 2010-10-21 2012-04-26 Monash University Antimicrobial compounds
WO2012168820A1 (en) 2011-06-08 2012-12-13 Pfizer Inc. Polymyxin derivatives useful as antibacterial agents
EP2780357A1 (en) * 2011-11-18 2014-09-24 Novacta Biosystems Limited Polymyxin derivatives
HUE059544T2 (hu) 2013-05-22 2022-11-28 Spero Therapeutics Inc Polimixin-származékok és ezek alkalmazása kombinációs terápiában különbözõ antibiotikumokkal
HRP20220387T1 (hr) 2014-03-11 2022-05-27 Spero Therapeutics, Inc. Derivati polimiksina i njihova upotreba u kombinacijskoj terapiji zajedno s različitim antibioticima
HUE068512T2 (hu) 2014-04-01 2024-12-28 Univ Monash Polimixin-származékok mint antimikrobális vegyületek
AU2015352440B2 (en) 2014-11-26 2020-02-06 Spero Therapeutics, Inc. Compounds
KR20170098821A (ko) * 2014-12-17 2017-08-30 에프. 호프만-라 로슈 아게 소르타아제를 사용한 １ 단계로의 이중 폴리펩티드 컨쥬게이션을 위한 효소 원-포트 반응
WO2016166103A1 (en) * 2015-04-13 2016-10-20 Xellia Pharmaceuticals Aps Polymyxin derivatives
EP3356387B1 (en) * 2015-09-29 2024-06-26 Monash University Antimicrobial polymyxin derivative compounds
WO2017218867A1 (en) * 2016-06-16 2017-12-21 Aeras Tuberculosis compositions and methods of treating or preventing tuberculosis
EA202092819A1 (ru) * 2018-06-25 2021-05-21 Сперо Терапьютикс, Инк. Соединения
WO2020014501A1 (en) 2018-07-11 2020-01-16 Cidara Therapeutics, Inc. Compositions and methods for the treatment of bacterial infections

Also Published As

Publication number Publication date
FI3810633T3 (fi) 2024-02-09
SG11202012747VA (en) 2021-01-28
HRP20240028T1 (hr) 2024-03-29
US11459357B2 (en) 2022-10-04
MA52946B1 (fr) 2024-03-29
ZA202301937B (en) 2023-09-27
CN112789287A (zh) 2021-05-11
IL279620B1 (en) 2025-11-01
CN112789287B (zh) 2024-06-21
IL279620A (en) 2021-03-01
BR112020026663A2 (pt) 2021-03-23
PH12020552240A1 (en) 2021-08-16
AU2024203362A1 (en) 2024-06-06
UA128162C2 (uk) 2024-04-24
AR116663A1 (es) 2021-06-02
SI3810633T1 (sl) 2024-04-30
TW202019949A (zh) 2020-06-01
JP2021528449A (ja) 2021-10-21
US20230012121A1 (en) 2023-01-12
LT3810633T (lt) 2024-01-10
HUE065134T2 (hu) 2024-05-28
EP3810633A1 (en) 2021-04-28
TW202446783A (zh) 2024-12-01
EP4316504A3 (en) 2024-04-17
PL3810633T3 (pl) 2024-04-08
MD3810633T2 (ro) 2024-05-31
AU2019294261A1 (en) 2021-02-04
EP3810633B1 (en) 2023-12-13
US20210246169A1 (en) 2021-08-12
IL323560A (en) 2025-11-01
EP4316504A2 (en) 2024-02-07
MA52946A (fr) 2021-04-28
ES2971732T3 (es) 2024-06-06
CO2020016080A2 (es) 2021-01-18
EA202092819A1 (ru) 2021-05-21
TWI851584B (zh) 2024-08-11
WO2020002325A1 (en) 2020-01-02
JP7488774B2 (ja) 2024-05-22
CA3103158A1 (en) 2020-01-02
RS65128B1 (sr) 2024-02-29
AU2019294261B2 (en) 2024-02-29
NZ771833A (en) 2024-09-27
MX2020013811A (es) 2021-03-09
CN118878638A (zh) 2024-11-01
JP2024109664A (ja) 2024-08-14
KR20210054500A (ko) 2021-05-13
PT3810633T (pt) 2024-02-19

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