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DK3840837T3 - Arginasehæmmere og fremgangsmåder til anvendelse deraf - Google Patents

Arginasehæmmere og fremgangsmåder til anvendelse deraf Download PDF

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Publication number
DK3840837T3
DK3840837T3 DK19758683.7T DK19758683T DK3840837T3 DK 3840837 T3 DK3840837 T3 DK 3840837T3 DK 19758683 T DK19758683 T DK 19758683T DK 3840837 T3 DK3840837 T3 DK 3840837T3
Authority
DK
Denmark
Prior art keywords
methods
arginase inhibitors
arginase
inhibitors
Prior art date
Application number
DK19758683.7T
Other languages
English (en)
Inventor
Dedong Wu
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of DK3840837T3 publication Critical patent/DK3840837T3/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/69Boron compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/22Boron compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02Boron compounds
    • C07F5/025Boronic and borinic acid compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK19758683.7T 2018-08-22 2019-08-21 Arginasehæmmere og fremgangsmåder til anvendelse deraf DK3840837T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862721113P 2018-08-22 2018-08-22
PCT/EP2019/072341 WO2020038983A1 (en) 2018-08-22 2019-08-21 Arginase inhibitors and methods of use thereof

Publications (1)

Publication Number Publication Date
DK3840837T3 true DK3840837T3 (da) 2024-06-10

Family

ID=67742403

Family Applications (1)

Application Number Title Priority Date Filing Date
DK19758683.7T DK3840837T3 (da) 2018-08-22 2019-08-21 Arginasehæmmere og fremgangsmåder til anvendelse deraf

Country Status (25)

Country Link
US (1) US11952392B2 (da)
EP (2) EP4371614A3 (da)
JP (1) JP7441210B2 (da)
KR (1) KR102668252B1 (da)
CN (1) CN112584900B (da)
AU (1) AU2019323663B2 (da)
CA (1) CA3109100A1 (da)
CL (1) CL2021000430A1 (da)
DK (1) DK3840837T3 (da)
EA (1) EA202190532A1 (da)
ES (1) ES2980252T3 (da)
FI (1) FI3840837T3 (da)
HR (1) HRP20240694T1 (da)
HU (1) HUE066903T2 (da)
IL (1) IL280924B2 (da)
LT (1) LT3840837T (da)
MA (1) MA53427B1 (da)
MX (1) MX2021002042A (da)
PL (1) PL3840837T3 (da)
PT (1) PT3840837T (da)
RS (1) RS65608B1 (da)
SG (1) SG11202101618PA (da)
SI (1) SI3840837T1 (da)
SM (1) SMT202400221T1 (da)
WO (1) WO2020038983A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MA52422A (fr) 2018-02-27 2021-01-06 Incyte Corp Imidazopyrimidines et triazolopyrimidines en tant qu'inhibiteurs a2a/a2b
MX2020012376A (es) 2018-05-18 2021-03-09 Incyte Corp Derivados de pirimidina fusionados como inhibidores de los receptores de adenosina a2a/a2b.
MA53097A (fr) 2018-07-05 2021-05-12 Incyte Corp Dérivés de pyrazine fusionnés en tant qu'inhibiteurs d'a2a/a2b
TWI829857B (zh) 2019-01-29 2024-01-21 美商英塞特公司 作為a2a / a2b抑制劑之吡唑并吡啶及三唑并吡啶
PT3921033T (pt) 2019-02-08 2023-10-11 Astrazeneca Ab Inibidores de arginase e métodos de utilização dos mesmos

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX348422B (es) * 2010-04-22 2017-06-12 Mars Inc Inhibidores de arginasa y sus aplicaciones terapeuticas.
US10143699B2 (en) 2015-06-23 2018-12-04 Calithera Biosciences, Inc. Compositions and methods for inhibiting arginase activity
EP3538111B1 (en) 2016-11-08 2022-01-19 Calithera Biosciences, Inc. Arginase inhibitor combination therapies
ES2970715T3 (es) * 2016-12-22 2024-05-30 Prec Pharmaceuticals Inc Composiciones y métodos para inhibir la actividad de la arginasa
CR20200418A (es) 2018-02-17 2020-10-27 Astrazeneca Ab Inhibidores de orginasa y sus mètodos de uso antecedentes
US12215116B2 (en) 2018-03-13 2025-02-04 Merck Sharp & Dohme Llc Arginase inhibitors and methods of use
CN111770756B (zh) 2018-04-27 2023-03-31 四川科伦博泰生物医药股份有限公司 非天然氨基酸类衍生物、包含其的药物组合物及其制备方法和用途

Also Published As

Publication number Publication date
US20210332068A1 (en) 2021-10-28
ES2980252T3 (es) 2024-09-30
IL280924B2 (en) 2024-10-01
IL280924A (en) 2021-04-29
CL2021000430A1 (es) 2021-09-03
SI3840837T1 (sl) 2024-07-31
MA53427B1 (fr) 2024-06-28
PT3840837T (pt) 2024-06-14
EP3840837A1 (en) 2021-06-30
AU2019323663B2 (en) 2022-07-14
CN112584900B (zh) 2025-07-15
KR20210049120A (ko) 2021-05-04
SG11202101618PA (en) 2021-03-30
EP4371614A3 (en) 2025-09-24
MX2021002042A (es) 2021-04-28
JP2021535111A (ja) 2021-12-16
HUE066903T2 (hu) 2024-09-28
US11952392B2 (en) 2024-04-09
AU2019323663A1 (en) 2021-04-08
RS65608B1 (sr) 2024-07-31
PL3840837T3 (pl) 2024-08-19
WO2020038983A1 (en) 2020-02-27
EP4371614A2 (en) 2024-05-22
KR102668252B1 (ko) 2024-05-21
IL280924B1 (en) 2024-06-01
EP3840837B1 (en) 2024-03-20
CN112584900A (zh) 2021-03-30
LT3840837T (lt) 2024-06-10
JP7441210B2 (ja) 2024-02-29
EA202190532A1 (ru) 2021-07-08
CA3109100A1 (en) 2020-02-27
HRP20240694T1 (hr) 2024-08-16
SMT202400221T1 (it) 2024-07-09
MA53427A (fr) 2021-12-01
FI3840837T3 (fi) 2024-06-03

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