[go: up one dir, main page]

DK3721221T3 - System og fremgangsmåde til anvendt radial-teknologikromatografi - Google Patents

System og fremgangsmåde til anvendt radial-teknologikromatografi

Info

Publication number
DK3721221T3
DK3721221T3 DK18855121.2T DK18855121T DK3721221T3 DK 3721221 T3 DK3721221 T3 DK 3721221T3 DK 18855121 T DK18855121 T DK 18855121T DK 3721221 T3 DK3721221 T3 DK 3721221T3
Authority
DK
Denmark
Prior art keywords
applied radial
technology chromatography
radial technology
chromatography
technology
Prior art date
Application number
DK18855121.2T
Other languages
English (en)
Inventor
Derek W K Levison
Alistair J Hurst
Original Assignee
Emp Biotech Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Emp Biotech Gmbh filed Critical Emp Biotech Gmbh
Application granted granted Critical
Publication of DK3721221T3 publication Critical patent/DK3721221T3/da

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/20—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the sorbent material
    • B01D15/206—Packing or coating
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28002—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their physical properties
    • B01J20/28004—Sorbent size or size distribution, e.g. particle size
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28014—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
    • B01J20/28016—Particle form
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28014—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
    • B01J20/28052—Several layers of identical or different sorbents stacked in a housing, e.g. in a column
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28054—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
    • B01J20/28078—Pore diameter
    • B01J20/28083—Pore diameter being in the range 2-50 nm, i.e. mesopores
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28054—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
    • B01J20/28078—Pore diameter
    • B01J20/28085—Pore diameter being more than 50 nm, i.e. macropores
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/50—Conditioning of the sorbent material or stationary liquid
    • G01N30/52—Physical parameters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N2030/386—Radial chromatography, i.e. with mobile phase traversing radially the stationary phase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/50—Conditioning of the sorbent material or stationary liquid
    • G01N30/52—Physical parameters
    • G01N2030/524—Physical parameters structural properties
    • G01N2030/525—Physical parameters structural properties surface properties, e.g. porosity

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nanotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Health & Medical Sciences (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Vaporization, Distillation, Condensation, Sublimation, And Cold Traps (AREA)
DK18855121.2T 2017-12-07 2018-12-07 System og fremgangsmåde til anvendt radial-teknologikromatografi DK3721221T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762595826P 2017-12-07 2017-12-07
PCT/IB2018/001561 WO2019111057A1 (en) 2017-12-07 2018-12-07 System and method of applied radial technology chromatography

Publications (1)

Publication Number Publication Date
DK3721221T3 true DK3721221T3 (da) 2025-09-22

Family

ID=65685830

Family Applications (1)

Application Number Title Priority Date Filing Date
DK18855121.2T DK3721221T3 (da) 2017-12-07 2018-12-07 System og fremgangsmåde til anvendt radial-teknologikromatografi

Country Status (14)

Country Link
US (3) US11325104B2 (da)
EP (2) EP4596099A3 (da)
JP (2) JP7618446B2 (da)
KR (2) KR102810212B1 (da)
CN (1) CN111602050B (da)
AU (2) AU2018379811B2 (da)
CA (1) CA3084729A1 (da)
DK (1) DK3721221T3 (da)
ES (1) ES3042507T3 (da)
IL (2) IL316292A (da)
PT (1) PT3721221T (da)
SG (1) SG11202005247XA (da)
TW (1) TWI816721B (da)
WO (1) WO2019111057A1 (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022229381A1 (en) 2021-04-29 2022-11-03 Univercells Technologies Sa Systems and methods for the continuous production and purification of biologics

Family Cites Families (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3782075A (en) 1972-04-07 1974-01-01 Du Pont Completely porous microspheres for chromatographic uses
IT1133340B (it) 1980-09-26 1986-07-09 Lussoria Antonietta Sciolla Apparecchiatura per la miscelazione di gas in un liquido,particolarmente per la ossigenazione di acque inquinate
US4751004A (en) 1981-09-18 1988-06-14 The Dow Chemical Company Liquid chromatographic method and apparatus with a packed tube membrane device for post-column derivatization/suppression reactions
DE3427410C1 (de) 1984-07-25 1986-02-06 Jörg Wolfgang 4130 Moers Buddenberg Silo mit kreisrundem Grundriss fuer Schuettgueter und einem an einer Stuetzsaeule heb- und senkbar angeordneten Querfoerderer
US4676898A (en) 1985-11-04 1987-06-30 Sepragen Corporation Chromatography column using horizontal flow
US4627918A (en) 1985-11-04 1986-12-09 Sepragen Corporation Chromatography column using horizontal flow
US5135650A (en) * 1988-12-22 1992-08-04 Bio-Rad Laboratories, Inc. Chromatography stationary phase material for high performance liquid chromatography
US5433847A (en) * 1989-11-01 1995-07-18 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Radial flow chromatography
WO1991016116A1 (en) 1990-04-23 1991-10-31 Cellpro Incorporated Immunoselection device and method
US5128291A (en) * 1990-12-11 1992-07-07 Wax Michael J Porous titania or zirconia spheres
US5466377A (en) 1994-01-19 1995-11-14 Grandics; Peter Chromatography media and their uses
US5429746A (en) * 1994-02-22 1995-07-04 Smith Kline Beecham Corporation Antibody purification
WO1997043024A1 (en) 1996-05-16 1997-11-20 Dyax Corporation Liquid chromatography column
US5817354A (en) 1996-08-22 1998-10-06 Sepragen Corporation High throughput debittering
CN1087641C (zh) 1997-01-24 2002-07-17 中国科学院大连化学物理研究所 径向色谱柱用金属螯合亲和膜色谱介质的合成方法
JP2001523811A (ja) 1997-11-14 2001-11-27 ダイアックス コーポレイション 液体クロマトグラフィカラム
US6022477A (en) 1997-11-14 2000-02-08 New Jersey Institute Of Technology Method and apparatus for isolation purification of biomolecules
US6986847B2 (en) 2002-05-10 2006-01-17 New Jersey Institute Of Technology Method and apparatus for isolation and purification of biomolecules
WO2005018802A2 (en) * 2003-08-25 2005-03-03 Cabot Corporation Compositions and chromatography materials for bioseparation
US7479222B2 (en) 2004-02-05 2009-01-20 Millipore Corporation Porous adsorptive or chromatographic media
WO2005077529A1 (en) 2004-02-05 2005-08-25 Millipore Corporation Porous adsorptive or chromatographic media
CN101119797A (zh) * 2005-02-14 2008-02-06 通用电气健康护理生物科学股份公司 液相色谱法
EP1957195A1 (en) * 2005-12-07 2008-08-20 MIP Technologies AB Methods for making polymer beads
US20070138076A1 (en) 2005-12-16 2007-06-21 Fluidigm Corporation Devices and methods for microfluidic chromatography
SG135990A1 (en) * 2006-03-16 2007-10-29 Nat Environment Agency Competitive enzyme linked immunosorbent assay (c-elisa) for the detection of a flavivirus specific antibody
DE102007008663A1 (de) 2007-02-20 2008-08-21 Merck Patent Gmbh Bindemittel
KR20170001720A (ko) * 2007-03-14 2017-01-04 다케다 백신즈 인코포레이티드 바이러스 유사 입자 정제
CN101385909B (zh) * 2008-09-12 2011-11-23 天津科技大学 径向色谱纯化天然可溶性多糖的方法
CA2755247A1 (en) 2009-03-13 2010-09-16 Terrasep, Llc Methods and apparatus for centrifugal liquid chromatography
US8293101B2 (en) 2009-03-13 2012-10-23 Terrasep, Llc Methods and apparatus for centrifugal liquid chromatography
WO2011035282A1 (en) 2009-09-21 2011-03-24 Ge Healthcare Bio-Sciences Ab Dual capture separation
US20110097464A1 (en) 2009-10-22 2011-04-28 Ge Healthcare Bio-Sciences Ab Method for liquid processing
JP2011179401A (ja) 2010-03-01 2011-09-15 Mitsubishi Heavy Ind Ltd ウエストゲートバルブ装置
CN103347581A (zh) 2010-03-25 2013-10-09 西门子私人有限公司 改善的径向流动管柱
EP2561345A4 (en) 2010-04-05 2015-02-25 Purdue Research Foundation METHOD OF PACKAGING CHROMATOGRAPHIC PILLARS
EP2598223B1 (en) 2010-07-30 2022-04-06 EMD Millipore Corporation Chromatography media and method
US8658039B2 (en) * 2010-11-17 2014-02-25 Brigham Young University Sonication for improved particle size distribution of core-shell particles
EP2652492A1 (en) 2010-12-16 2013-10-23 Marcellus Johannes Hubertus Raedts Disposable horizontal or radial flow type chromatographic column
JP2012185067A (ja) 2011-03-07 2012-09-27 Doshisha 管径方向分配クロマトグラフィーを用いた混合物の分離方法
CN102323360A (zh) * 2011-05-19 2012-01-18 周鑫 一种用于液相色谱柱的环型筛板
US9486799B2 (en) 2012-09-11 2016-11-08 Dionex Corporation Glycidol functionalized anion exchange stationary phases
BR112015005937A2 (pt) 2012-09-17 2017-07-04 Grace W R & Co meios e dispositivos cromatográficos
CN102989263A (zh) 2012-10-11 2013-03-27 田原宇 高效径向流吸附塔
EP2742982A1 (en) 2012-12-12 2014-06-18 Nederlandse Organisatie voor toegepast -natuurwetenschappelijk onderzoek TNO Highly productive simulated moving bed chromatographic separation
US10107729B2 (en) * 2013-02-15 2018-10-23 Douglas T. Gjerde Isolation, detection and use of biological cells
WO2014142940A1 (en) 2013-03-15 2014-09-18 Evoqua Water Technologies Pte. Ltd. Chemical and biological wastewater treatment system
HUE042072T2 (hu) * 2013-03-15 2019-06-28 Glaxosmithkline Biologicals Sa Eljárások RNS tisztítására
JP2016521858A (ja) * 2013-06-11 2016-07-25 ウオーターズ・テクノロジーズ・コーポレイシヨン 表面多孔性材料を含むクロマトグラフィーカラムおよび分離デバイス、および超臨界流体クロマトグラフィーおよび他のクロマトグラフィーのためのこれらの使用
US9375657B2 (en) 2013-11-12 2016-06-28 Orochem Technologies, Inc. Flash chromatography column apparatus
ES2887110T3 (es) * 2014-01-16 2021-12-21 Grace W R & Co Medios para cromatografía de afinidad y dispositivos para cromatografía
WO2015159414A1 (ja) 2014-04-17 2015-10-22 ユニサンティス エレクトロニクス シンガポール プライベート リミテッド 柱状半導体メモリ装置及びその製造方法
WO2015189916A1 (ja) 2014-06-10 2015-12-17 ユニサンティス エレクトロニクス シンガポール プライベート リミテッド 柱状半導体メモリ装置及びその製造方法
JP2020017796A (ja) * 2018-07-23 2020-01-30 キヤノン株式会社 撮像装置および撮像システム

Also Published As

Publication number Publication date
SG11202005247XA (en) 2020-07-29
US11325104B2 (en) 2022-05-10
IL275112A (en) 2020-07-30
CA3084729A1 (en) 2019-06-13
PT3721221T (pt) 2025-09-18
IL275112B1 (en) 2024-11-01
US20240157332A1 (en) 2024-05-16
US12318759B2 (en) 2025-06-03
KR20250077599A (ko) 2025-05-30
CN111602050A (zh) 2020-08-28
EP4596099A2 (en) 2025-08-06
WO2019111057A1 (en) 2019-06-13
IL316292A (en) 2024-12-01
KR102810212B1 (ko) 2025-05-21
CN111602050B (zh) 2024-04-26
TW201934997A (zh) 2019-09-01
AU2018379811A1 (en) 2020-07-02
EP3721221B1 (en) 2025-06-18
ES3042507T3 (en) 2025-11-21
JP7618446B2 (ja) 2025-01-21
JP2021505387A (ja) 2021-02-18
IL275112B2 (en) 2025-03-01
AU2024204668B2 (en) 2025-06-26
US20220297087A1 (en) 2022-09-22
AU2018379811B2 (en) 2024-04-11
TWI816721B (zh) 2023-10-01
US20190176127A1 (en) 2019-06-13
AU2024204668A1 (en) 2024-07-25
US11731107B2 (en) 2023-08-22
BR112020011341A2 (pt) 2020-11-17
KR20200097287A (ko) 2020-08-18
EP4596099A3 (en) 2025-11-19
EP3721221A1 (en) 2020-10-14
JP2025022899A (ja) 2025-02-14

Similar Documents

Publication Publication Date Title
EP3525009C0 (en) SATELLITE POSITIONING METHOD AND SYSTEM
DK3642743T3 (da) Fremgangsmåde og system til computerunderstøttet triage
DK3664245T3 (da) Styresystem og styringsmetode til parallelt omformersystem
DK3532838T3 (da) Fremgangsmåder og systemer til kromatografidataanalyse
DK3536008T3 (da) System og fremgangsmåde til udløsning af strålegenopretning
DK3539405T3 (da) Fastgørelsesindretning og fremgangsmåde til samling deraf
DK3398022T3 (da) Systemer og fremgangsmåder til tilpasning af uav-bane
DK3265947T3 (da) Fremgangsmåde og system til kryptering
DK4280177T3 (da) Systemer og fremgangsmåder til at påføre markeringer
DK3328285T3 (da) Fremgangsmåde og system til korrigering af fedt-inducerede aberrationer
DK4238495T3 (da) Medicinsk system og fremgangsmåde til fremstilling deraf
IS3065B (is) Dælukerfi og aðferð
DK3466167T3 (da) Fremgangsmåde og indretning til synkronisering
DK3231131T3 (da) System og fremgangsmåde til at erstatte fælles identificerende data
DK4008994T3 (da) Fremgangsmåde og system til vejovervågning
EP3617748A4 (en) POSITIONING METHOD, DEVICE AND SYSTEM
DK3367847T3 (da) Understøtningsplade, sengeanordning og fremgangsmåde til montering
DK3727623T3 (da) Legesystem og fremgangsmåde til detektering af legetøjselementer
DK3356615T3 (da) Monteringssystem til ovenlysvindue og anordning
DK3589742T3 (da) Fremgangsmåde til detektering
DK3020881T3 (da) Fremgangsmåde og system til tilvejebringelse af eftermonteret isolering
DK3522841T3 (da) Indretning til intrauterint system og indføringsmiddel dertil
DK3580736T3 (da) Indretning, system og fremgangsmåde til trafikstyring
DK3615141T3 (da) System og fremgangsmåde til bestråling af et objekt
DK3697520T3 (da) Glykoltørringsanlæg og fremgangsmåde til glykoltørring