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DK3766884T3 - Krystalform og salttype af triazolopyrimidinforbindelse og fremstillingsfremgangsmåde dertil - Google Patents

Krystalform og salttype af triazolopyrimidinforbindelse og fremstillingsfremgangsmåde dertil Download PDF

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Publication number
DK3766884T3
DK3766884T3 DK19793622.2T DK19793622T DK3766884T3 DK 3766884 T3 DK3766884 T3 DK 3766884T3 DK 19793622 T DK19793622 T DK 19793622T DK 3766884 T3 DK3766884 T3 DK 3766884T3
Authority
DK
Denmark
Prior art keywords
crystal form
manufacturing procedure
salt type
triazolopyrimidine compound
triazolopyrimidine
Prior art date
Application number
DK19793622.2T
Other languages
English (en)
Inventor
Kevin X Chen
Yanxin Yu
Xinde Chen
Li Zhang
Zhaoguo Chen
Cheng Xie
Original Assignee
Medshine Discovery Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medshine Discovery Inc filed Critical Medshine Discovery Inc
Application granted granted Critical
Publication of DK3766884T3 publication Critical patent/DK3766884T3/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK19793622.2T 2018-04-28 2019-04-28 Krystalform og salttype af triazolopyrimidinforbindelse og fremstillingsfremgangsmåde dertil DK3766884T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201810399876 2018-04-28
PCT/CN2019/084822 WO2019206336A1 (zh) 2018-04-28 2019-04-28 一种三唑并嘧啶类化合物的晶型、盐型及其制备方法

Publications (1)

Publication Number Publication Date
DK3766884T3 true DK3766884T3 (da) 2022-03-28

Family

ID=68294924

Family Applications (1)

Application Number Title Priority Date Filing Date
DK19793622.2T DK3766884T3 (da) 2018-04-28 2019-04-28 Krystalform og salttype af triazolopyrimidinforbindelse og fremstillingsfremgangsmåde dertil

Country Status (9)

Country Link
US (1) US11649239B2 (da)
EP (1) EP3766884B1 (da)
JP (1) JP7406691B2 (da)
CN (1) CN112105617B (da)
DK (1) DK3766884T3 (da)
ES (1) ES2908424T3 (da)
PL (1) PL3766884T3 (da)
PT (1) PT3766884T (da)
WO (1) WO2019206336A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7406691B2 (ja) * 2018-04-28 2023-12-28 イノレイク・バイオファーマ(ハンジョウ)・カンパニー・リミテッド トリアゾロピリミジン系化合物の結晶形、塩のタイプおよびその調製方法
TWI820209B (zh) 2018-09-12 2023-11-01 大陸商迪哲(江蘇)醫藥股份有限公司 三唑并-嘧啶化合物及其用途
WO2020106560A1 (en) 2018-11-20 2020-05-28 Merck Sharp & Dohme Corp. Substituted amino triazolopyrimidine and amino triazolopyrazine adenosine receptor antagonists, pharmaceutical compositions and their use
AU2020337350A1 (en) * 2019-08-26 2022-03-10 Incyte Corporation Triazolopyrimidines as A2A / A2B inhibitors
CN120022278A (zh) * 2023-11-22 2025-05-23 英诺湖医药(杭州)有限公司 用于治疗癌症的化合物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU743910B2 (en) * 1997-03-24 2002-02-07 Kyowa Hakko Kirin Co., Ltd. {1,2,4}triazolo{1,5-c}pyrimidine derivatives
AR038366A1 (es) 2001-11-30 2005-01-12 Schering Corp Compuestos de 1,2,4-triazolo [1,5-c] pirimidinas sustituidas, antagonistas del receptor de adenosina a2a, composiciones farmaceuticas, el uso de dichos compuestos para la manufactura de un medicamento para el tratamiento de enfermedades del sistema nervioso central y un kit que comprende combinacion
CA2500228A1 (en) * 2002-09-24 2004-04-08 Kyowa Hakko Kogyo Co., Ltd. [1,2,4]-triazolo[1,5-c]pyrimidine derivative
DK3611174T3 (da) 2017-04-07 2022-07-04 Medshine Discovery Inc [1,2,4]triazolo[1,5-c]pyrimidinderivat som a2a-receptorinhibitor
JP7406691B2 (ja) * 2018-04-28 2023-12-28 イノレイク・バイオファーマ(ハンジョウ)・カンパニー・リミテッド トリアゾロピリミジン系化合物の結晶形、塩のタイプおよびその調製方法

Also Published As

Publication number Publication date
PT3766884T (pt) 2022-03-31
ES2908424T3 (es) 2022-04-29
JP2021522335A (ja) 2021-08-30
EP3766884A1 (en) 2021-01-20
US11649239B2 (en) 2023-05-16
US20210094957A1 (en) 2021-04-01
CN112105617B (zh) 2022-04-05
PL3766884T3 (pl) 2022-07-18
CN112105617A (zh) 2020-12-18
WO2019206336A1 (zh) 2019-10-31
JP7406691B2 (ja) 2023-12-28
EP3766884B1 (en) 2022-02-09
EP3766884A4 (en) 2021-03-31

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