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DK3523339T3 - Smørende blok-copolymerer og deres anvendelse som biomimetiske grænsesmøremidler - Google Patents

Smørende blok-copolymerer og deres anvendelse som biomimetiske grænsesmøremidler

Info

Publication number
DK3523339T3
DK3523339T3 DK17859078.2T DK17859078T DK3523339T3 DK 3523339 T3 DK3523339 T3 DK 3523339T3 DK 17859078 T DK17859078 T DK 17859078T DK 3523339 T3 DK3523339 T3 DK 3523339T3
Authority
DK
Denmark
Prior art keywords
biomimetric
block copolymers
lubricant block
lubricants
interface
Prior art date
Application number
DK17859078.2T
Other languages
English (en)
Inventor
David Putnam
Lawrence Bonassar
Zhexun Sun
Original Assignee
Univ Cornell
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Cornell filed Critical Univ Cornell
Application granted granted Critical
Publication of DK3523339T3 publication Critical patent/DK3523339T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/785Polymers containing nitrogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/795Polymers containing sulfur
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10Esters
    • C08F220/26Esters containing oxygen in addition to the carboxy oxygen
    • C08F220/28Esters containing oxygen in addition to the carboxy oxygen containing no aromatic rings in the alcohol moiety
    • C08F220/285Esters containing oxygen in addition to the carboxy oxygen containing no aromatic rings in the alcohol moiety and containing a polyether chain in the alcohol moiety
    • C08F220/286Esters containing oxygen in addition to the carboxy oxygen containing no aromatic rings in the alcohol moiety and containing a polyether chain in the alcohol moiety and containing polyethylene oxide in the alcohol moiety, e.g. methoxy polyethylene glycol (meth)acrylate
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F293/00Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule
    • C08F293/005Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule using free radical "living" or "controlled" polymerisation, e.g. using a complexing agent
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00Chemical modification by after-treatment
    • C08F8/44Preparation of metal salts or ammonium salts
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2438/00Living radical polymerisation
    • C08F2438/03Use of a di- or tri-thiocarbonylthio compound, e.g. di- or tri-thioester, di- or tri-thiocarbamate, or a xanthate as chain transfer agent, e.g . Reversible Addition Fragmentation chain Transfer [RAFT] or Macromolecular Design via Interchange of Xanthates [MADIX]
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2800/00Copolymer characterised by the proportions of the comonomers expressed
    • C08F2800/10Copolymer characterised by the proportions of the comonomers expressed as molar percentages
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2810/00Chemical modification of a polymer
    • C08F2810/50Chemical modification of a polymer wherein the polymer is a copolymer and the modification is taking place only on one or more of the monomers present in minority

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Graft Or Block Polymers (AREA)
  • Materials For Medical Uses (AREA)
DK17859078.2T 2016-10-04 2017-10-04 Smørende blok-copolymerer og deres anvendelse som biomimetiske grænsesmøremidler DK3523339T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662403962P 2016-10-04 2016-10-04
PCT/US2017/055057 WO2018067648A1 (en) 2016-10-04 2017-10-04 Lubricating block copolymers and their use as biomimetic boundary lubricants

Publications (1)

Publication Number Publication Date
DK3523339T3 true DK3523339T3 (da) 2025-08-25

Family

ID=61831218

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17859078.2T DK3523339T3 (da) 2016-10-04 2017-10-04 Smørende blok-copolymerer og deres anvendelse som biomimetiske grænsesmøremidler

Country Status (7)

Country Link
US (2) US11376276B2 (da)
EP (1) EP3523339B1 (da)
JP (2) JP7085536B2 (da)
CN (2) CN110050003B (da)
DK (1) DK3523339T3 (da)
ES (1) ES3039978T3 (da)
WO (1) WO2018067648A1 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110050003B (zh) 2016-10-04 2022-07-22 康奈尔大学 润滑嵌段共聚物及其作为仿生型界面润滑剂的用途
CN110522953B (zh) * 2018-05-24 2022-02-15 中国科学院兰州化学物理研究所 一种仿生关节润滑剂及其制备方法
WO2025023312A1 (ja) * 2023-07-26 2025-01-30 株式会社高研 コラーゲン結合型膜透過性ペプチド、並びに、該ペプチド及びコラーゲン若しくはコラーゲン誘導体を含む運搬体
WO2025036294A1 (zh) * 2023-08-11 2025-02-20 科凝生物制药(深圳)有限公司 嵌段式共聚物的润滑组合物及其用途

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3110615A (en) * 1957-09-30 1963-11-12 Congoleum Nairn Inc Urethane coating for cork surface and process therefor
US6024954A (en) * 1994-12-12 2000-02-15 Allergan Compositions and methods for disinfecting contact lenses and preserving contact lens care products
WO2002077075A1 (fr) 2001-03-22 2002-10-03 Rhodia Chimie Procede de fabrication de particules colloidales de forme controlee avec des copolymeres a blocs hydrosolubles comprenant un bloc hydrophobe et un bloc hydrophile
US7879820B2 (en) * 2002-04-22 2011-02-01 L'oreal S.A. Use of a cyclodextrin as pearlescent agent and pearlescent compositions
US20090018270A1 (en) * 2003-09-03 2009-01-15 Regan Crooks Copolymer having a controlled structure and use thereof
US20090088846A1 (en) * 2007-04-17 2009-04-02 David Myung Hydrogel arthroplasty device
AU2005291721A1 (en) * 2004-10-07 2006-04-13 Coloplast A/S A medical device having a wetted hydrophilic coating
WO2008130604A2 (en) * 2007-04-17 2008-10-30 The Board Of Trustees Of The Leland Stanford Junior University Hydrogel arthroplasty device
CN102066444A (zh) * 2008-05-13 2011-05-18 华盛顿大学 胶束装配体
JP5540599B2 (ja) * 2008-10-31 2014-07-02 Jsr株式会社 着色層形成用感放射線性組成物、カラーフィルタ及びカラー液晶表示素子
US20140051771A1 (en) * 2012-08-20 2014-02-20 Ticona Llc Biomedical Devices Comprising Molded Polyethylene Components
CN104870020A (zh) * 2012-10-19 2015-08-26 康奈尔大学 用于关节软骨的仿生型界面润滑剂
ES2792919T3 (es) 2013-04-01 2020-11-12 Terumo Corp Dispositivo médico y método para fabricar dispositivo médico
WO2015054452A1 (en) * 2013-10-11 2015-04-16 Basf Se Keratin conditioning bio-based polymers for use in personal care compositions
US10717803B2 (en) * 2014-03-27 2020-07-21 Sika Technology Ag Block copolymer
CA2955048C (en) * 2014-07-14 2020-11-03 University Of Utah Research Foundation In situ solidifying compositions and methods of making and using therof
US10646574B2 (en) * 2014-07-21 2020-05-12 Board Of Regents, The University Of Texas System Formulations of intraarticular pharmaceutical agents and methods for preparing and using the same
CN110050003B (zh) * 2016-10-04 2022-07-22 康奈尔大学 润滑嵌段共聚物及其作为仿生型界面润滑剂的用途

Also Published As

Publication number Publication date
EP3523339A1 (en) 2019-08-14
CN110050003B (zh) 2022-07-22
US20190231811A1 (en) 2019-08-01
US20230210892A1 (en) 2023-07-06
EP3523339B1 (en) 2025-05-14
JP7085536B2 (ja) 2022-06-16
CN110050003A (zh) 2019-07-23
US11376276B2 (en) 2022-07-05
US12364710B2 (en) 2025-07-22
JP2019534922A (ja) 2019-12-05
WO2018067648A1 (en) 2018-04-12
EP3523339A4 (en) 2020-06-03
ES3039978T3 (en) 2025-10-28
CN115386055B (zh) 2025-07-08
JP2022088630A (ja) 2022-06-14
CN115386055A (zh) 2022-11-25

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