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DK3523270T3 - METHOD OF MAKING CYCLOPROPYL-SUBSTITUTED ACETOPHENONES - Google Patents

METHOD OF MAKING CYCLOPROPYL-SUBSTITUTED ACETOPHENONES Download PDF

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Publication number
DK3523270T3
DK3523270T3 DK17780692.4T DK17780692T DK3523270T3 DK 3523270 T3 DK3523270 T3 DK 3523270T3 DK 17780692 T DK17780692 T DK 17780692T DK 3523270 T3 DK3523270 T3 DK 3523270T3
Authority
DK
Denmark
Prior art keywords
substituted acetophenones
cyclopropyl
making
making cyclopropyl
acetophenones
Prior art date
Application number
DK17780692.4T
Other languages
Danish (da)
Inventor
Christoph Schotes
Original Assignee
Bayer Cropscience Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Cropscience Ag filed Critical Bayer Cropscience Ag
Application granted granted Critical
Publication of DK3523270T3 publication Critical patent/DK3523270T3/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/36Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
    • C07C29/38Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
    • C07C29/40Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones with compounds containing carbon-to-metal bonds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/62Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/40Halogenated unsaturated alcohols
    • C07C33/50Halogenated unsaturated alcohols containing six-membered aromatic rings and other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • C07C45/57Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
    • C07C45/58Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in three-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/20Unsaturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/225Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/80Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
    • C07C49/813Ketones containing a keto group bound to a six-membered aromatic ring containing halogen polycyclic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/08Compounds containing oxirane rings with hydrocarbon radicals, substituted by halogen atoms, nitro radicals or nitroso radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/02Systems containing only non-condensed rings with a three-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DK17780692.4T 2016-10-05 2017-09-29 METHOD OF MAKING CYCLOPROPYL-SUBSTITUTED ACETOPHENONES DK3523270T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16192300 2016-10-05
PCT/EP2017/074802 WO2018065316A1 (en) 2016-10-05 2017-09-29 Method for producing cyclopropyl-substituted acetophenones

Publications (1)

Publication Number Publication Date
DK3523270T3 true DK3523270T3 (en) 2021-01-11

Family

ID=57103867

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17780692.4T DK3523270T3 (en) 2016-10-05 2017-09-29 METHOD OF MAKING CYCLOPROPYL-SUBSTITUTED ACETOPHENONES

Country Status (12)

Country Link
US (1) US10633321B2 (en)
EP (1) EP3523270B1 (en)
JP (1) JP6944519B2 (en)
KR (1) KR102440434B1 (en)
CN (1) CN109715595B (en)
BR (1) BR112019006963B1 (en)
DK (1) DK3523270T3 (en)
ES (1) ES2849961T3 (en)
IL (1) IL265779B (en)
MX (1) MX2019004024A (en)
TW (1) TWI751203B (en)
WO (1) WO2018065316A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113121322B (en) * 2019-12-30 2024-10-29 辽宁众辉生物科技有限公司 Synthesis method of 1- (4-chlorophenyl) -2-cyclopropyl-1-acetone
CN113121321B (en) * 2019-12-30 2023-11-24 江苏剑牌农化股份有限公司 Recovery and reuse method of a-R alkoxy p-chlorobenzyl phosphate monoester
CN116396151B (en) * 2022-12-06 2023-11-03 如东众意化工有限公司 Synthesis method of 1- (4-chlorophenyl) -2-cyclopropyl-1-acetone
CN117402044B (en) * 2023-10-17 2024-08-30 辽宁众辉生物科技有限公司 Synthesis method of 1- (4-chlorophenyl) -2-cyclopropyl-1-acetone

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101857576B (en) 2010-06-18 2012-07-25 中国科学院上海有机化学研究所 Method for preparing cyproconazole by cyclopropyl methyl ketone
CN102603508B (en) 2012-04-17 2014-03-12 江苏澄扬作物科技有限公司 Preparation method of 1-(4-chlorophenyl)-2-cyclopropyl-1-acetone and intermediate thereof as well as preparation method of intermediate
CN102942465B (en) * 2012-11-22 2015-10-28 江苏澄扬作物科技有限公司 The Preparation Method And Their Intermediate of 1-(4-chloro-phenyl-)-2-cyclopropyl-1-acetone

Also Published As

Publication number Publication date
EP3523270B1 (en) 2020-10-21
MX2019004024A (en) 2019-08-05
JP2019531300A (en) 2019-10-31
IL265779B (en) 2021-04-29
BR112019006963B1 (en) 2023-02-14
US20200002259A1 (en) 2020-01-02
WO2018065316A1 (en) 2018-04-12
ES2849961T3 (en) 2021-08-24
KR102440434B1 (en) 2022-09-05
CN109715595A (en) 2019-05-03
CN109715595B (en) 2022-03-11
US10633321B2 (en) 2020-04-28
EP3523270A1 (en) 2019-08-14
BR112019006963A2 (en) 2019-07-02
KR20190055837A (en) 2019-05-23
TW201833065A (en) 2018-09-16
JP6944519B2 (en) 2021-10-06
IL265779A (en) 2019-06-30
TWI751203B (en) 2022-01-01

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