DK3523270T3 - METHOD OF MAKING CYCLOPROPYL-SUBSTITUTED ACETOPHENONES - Google Patents
METHOD OF MAKING CYCLOPROPYL-SUBSTITUTED ACETOPHENONES Download PDFInfo
- Publication number
- DK3523270T3 DK3523270T3 DK17780692.4T DK17780692T DK3523270T3 DK 3523270 T3 DK3523270 T3 DK 3523270T3 DK 17780692 T DK17780692 T DK 17780692T DK 3523270 T3 DK3523270 T3 DK 3523270T3
- Authority
- DK
- Denmark
- Prior art keywords
- substituted acetophenones
- cyclopropyl
- making
- making cyclopropyl
- acetophenones
- Prior art date
Links
- 150000008062 acetophenones Chemical class 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
- C07C29/38—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
- C07C29/40—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones with compounds containing carbon-to-metal bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/62—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C33/40—Halogenated unsaturated alcohols
- C07C33/50—Halogenated unsaturated alcohols containing six-membered aromatic rings and other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
- C07C45/57—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
- C07C45/58—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in three-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
- C07C49/225—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
- C07C49/813—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen polycyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/08—Compounds containing oxirane rings with hydrocarbon radicals, substituted by halogen atoms, nitro radicals or nitroso radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Epoxy Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16192300 | 2016-10-05 | ||
| PCT/EP2017/074802 WO2018065316A1 (en) | 2016-10-05 | 2017-09-29 | Method for producing cyclopropyl-substituted acetophenones |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3523270T3 true DK3523270T3 (en) | 2021-01-11 |
Family
ID=57103867
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK17780692.4T DK3523270T3 (en) | 2016-10-05 | 2017-09-29 | METHOD OF MAKING CYCLOPROPYL-SUBSTITUTED ACETOPHENONES |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US10633321B2 (en) |
| EP (1) | EP3523270B1 (en) |
| JP (1) | JP6944519B2 (en) |
| KR (1) | KR102440434B1 (en) |
| CN (1) | CN109715595B (en) |
| BR (1) | BR112019006963B1 (en) |
| DK (1) | DK3523270T3 (en) |
| ES (1) | ES2849961T3 (en) |
| IL (1) | IL265779B (en) |
| MX (1) | MX2019004024A (en) |
| TW (1) | TWI751203B (en) |
| WO (1) | WO2018065316A1 (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113121322B (en) * | 2019-12-30 | 2024-10-29 | 辽宁众辉生物科技有限公司 | Synthesis method of 1- (4-chlorophenyl) -2-cyclopropyl-1-acetone |
| CN113121321B (en) * | 2019-12-30 | 2023-11-24 | 江苏剑牌农化股份有限公司 | Recovery and reuse method of a-R alkoxy p-chlorobenzyl phosphate monoester |
| CN116396151B (en) * | 2022-12-06 | 2023-11-03 | 如东众意化工有限公司 | Synthesis method of 1- (4-chlorophenyl) -2-cyclopropyl-1-acetone |
| CN117402044B (en) * | 2023-10-17 | 2024-08-30 | 辽宁众辉生物科技有限公司 | Synthesis method of 1- (4-chlorophenyl) -2-cyclopropyl-1-acetone |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101857576B (en) | 2010-06-18 | 2012-07-25 | 中国科学院上海有机化学研究所 | Method for preparing cyproconazole by cyclopropyl methyl ketone |
| CN102603508B (en) | 2012-04-17 | 2014-03-12 | 江苏澄扬作物科技有限公司 | Preparation method of 1-(4-chlorophenyl)-2-cyclopropyl-1-acetone and intermediate thereof as well as preparation method of intermediate |
| CN102942465B (en) * | 2012-11-22 | 2015-10-28 | 江苏澄扬作物科技有限公司 | The Preparation Method And Their Intermediate of 1-(4-chloro-phenyl-)-2-cyclopropyl-1-acetone |
-
2017
- 2017-09-29 DK DK17780692.4T patent/DK3523270T3/en active
- 2017-09-29 JP JP2019518027A patent/JP6944519B2/en active Active
- 2017-09-29 EP EP17780692.4A patent/EP3523270B1/en active Active
- 2017-09-29 CN CN201780057357.5A patent/CN109715595B/en active Active
- 2017-09-29 WO PCT/EP2017/074802 patent/WO2018065316A1/en not_active Ceased
- 2017-09-29 MX MX2019004024A patent/MX2019004024A/en unknown
- 2017-09-29 US US16/337,798 patent/US10633321B2/en active Active
- 2017-09-29 BR BR112019006963-1A patent/BR112019006963B1/en active IP Right Grant
- 2017-09-29 ES ES17780692T patent/ES2849961T3/en active Active
- 2017-09-29 KR KR1020197012673A patent/KR102440434B1/en active Active
- 2017-10-02 TW TW106134002A patent/TWI751203B/en active
-
2019
- 2019-04-02 IL IL265779A patent/IL265779B/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| EP3523270B1 (en) | 2020-10-21 |
| MX2019004024A (en) | 2019-08-05 |
| JP2019531300A (en) | 2019-10-31 |
| IL265779B (en) | 2021-04-29 |
| BR112019006963B1 (en) | 2023-02-14 |
| US20200002259A1 (en) | 2020-01-02 |
| WO2018065316A1 (en) | 2018-04-12 |
| ES2849961T3 (en) | 2021-08-24 |
| KR102440434B1 (en) | 2022-09-05 |
| CN109715595A (en) | 2019-05-03 |
| CN109715595B (en) | 2022-03-11 |
| US10633321B2 (en) | 2020-04-28 |
| EP3523270A1 (en) | 2019-08-14 |
| BR112019006963A2 (en) | 2019-07-02 |
| KR20190055837A (en) | 2019-05-23 |
| TW201833065A (en) | 2018-09-16 |
| JP6944519B2 (en) | 2021-10-06 |
| IL265779A (en) | 2019-06-30 |
| TWI751203B (en) | 2022-01-01 |
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