DK3570940T3 - Pridopidin til anvendelse i behandling af fragilt x-syndrom - Google Patents
Pridopidin til anvendelse i behandling af fragilt x-syndrom Download PDFInfo
- Publication number
- DK3570940T3 DK3570940T3 DK18741607.8T DK18741607T DK3570940T3 DK 3570940 T3 DK3570940 T3 DK 3570940T3 DK 18741607 T DK18741607 T DK 18741607T DK 3570940 T3 DK3570940 T3 DK 3570940T3
- Authority
- DK
- Denmark
- Prior art keywords
- pridopidine
- fragile
- syndrome
- treatment
- Prior art date
Links
- 208000001914 Fragile X syndrome Diseases 0.000 title 1
- YGKUEOZJFIXDGI-UHFFFAOYSA-N pridopidine Chemical compound C1CN(CCC)CCC1C1=CC=CC(S(C)(=O)=O)=C1 YGKUEOZJFIXDGI-UHFFFAOYSA-N 0.000 title 1
- 229950003764 pridopidine Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762448595P | 2017-01-20 | 2017-01-20 | |
| PCT/US2018/014169 WO2018136600A1 (en) | 2017-01-20 | 2018-01-18 | Use of pridopidine for the treatment of fragile x syndrome |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3570940T3 true DK3570940T3 (da) | 2024-02-19 |
Family
ID=62908348
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK18741607.8T DK3570940T3 (da) | 2017-01-20 | 2018-01-18 | Pridopidin til anvendelse i behandling af fragilt x-syndrom |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US11234973B2 (da) |
| EP (1) | EP3570940B1 (da) |
| JP (1) | JP7114604B2 (da) |
| CN (1) | CN110505902B (da) |
| AU (1) | AU2018210145B2 (da) |
| BR (1) | BR112019015000A2 (da) |
| CA (1) | CA3050700C (da) |
| DK (1) | DK3570940T3 (da) |
| ES (1) | ES2972205T3 (da) |
| HU (1) | HUE068300T2 (da) |
| IL (1) | IL268125B2 (da) |
| PL (1) | PL3570940T3 (da) |
| WO (1) | WO2018136600A1 (da) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG188298A1 (en) | 2010-09-03 | 2013-04-30 | Ivax Int Gmbh | Deuterated analogs of pridopidine useful as dopaminergic stabilizers |
| US11090297B2 (en) | 2013-06-21 | 2021-08-17 | Prilenia Neurotherapeutics Ltd. | Pridopidine for treating huntington's disease |
| EP4516356A3 (en) | 2016-08-24 | 2025-05-14 | Prilenia Neurotherapeutics Ltd. | Use of pridopidine for treating functional decline |
| BR112019003731A2 (pt) | 2016-08-24 | 2019-07-16 | Prilenia Therapeutics Dev Ltd | aplicação de pridopidina para tratamento de distonias |
| US12102627B2 (en) | 2016-09-16 | 2024-10-01 | Prilenia Neurotherapeutics Ltd. | Use of pridopidine for treating rett syndrome |
| JP2020533296A (ja) | 2017-09-08 | 2020-11-19 | プリレニア ニューロセラピューティクス リミテッド | 薬物誘発性ジスキネジアを治療するためのプリドピジン |
| US12036213B2 (en) | 2017-09-08 | 2024-07-16 | Prilenia Neurotherapeutics Ltd. | Pridopidine for treating drug induced dyskinesias |
| CN113395964A (zh) | 2019-02-04 | 2021-09-14 | 普瑞尼亚神经治疗有限公司 | 用于帕金森氏病和与帕金森症相关的其它疾病的低剂量普利多匹定 |
| EP4088721B1 (en) * | 2020-01-08 | 2025-09-17 | Neuroventi | Composition for treating fragile x syndrome or related developmental disorders, comprising lisuride compound as active ingredient |
| CN116472043A (zh) * | 2020-10-20 | 2023-07-21 | 普瑞尼亚神经治疗有限公司 | 普利多匹定和类似物用于治疗焦虑和抑郁的用途 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USRE46117E1 (en) | 1999-12-22 | 2016-08-23 | Teva Pharmaceuticals International Gmbh | Modulators of dopamine neurotransmission |
| SE9904724D0 (sv) | 1999-12-22 | 1999-12-22 | Carlsson A Research Ab | New modulators of dopamine neurotransmission I |
| DK1802573T3 (da) | 2004-10-13 | 2016-12-19 | Teva Pharmaceuticals Int Gmbh | Fremgangsmåde til syntese af 4-(3-methansulfonylphenyl)-1-n-propyl-piperidin. |
| CN101711236B (zh) | 2007-04-12 | 2012-10-31 | Nsab神经研究瑞典公司分公司 | 表现出改善的心血管副作用特性的多巴胺受体稳定剂/调节剂的n-氧化物和/或二-n-氧化物衍生物 |
| TW200848063A (en) * | 2007-04-23 | 2008-12-16 | Combinatorx Inc | Methods and compositions for the treatment of neurodegenerative disorders |
| EP2598662A1 (en) | 2010-07-02 | 2013-06-05 | Aktiebolaget SKF | Mechanical component and method for surface hardening |
| SG188298A1 (en) | 2010-09-03 | 2013-04-30 | Ivax Int Gmbh | Deuterated analogs of pridopidine useful as dopaminergic stabilizers |
| HRP20171478T1 (hr) * | 2011-01-27 | 2017-11-17 | Neuren Pharmaceuticals Limited | Liječenje poremećaja autističnog spektra pomoću glicil-l-2-metilprolil-l-glutaminske kiseline |
| EA023462B1 (ru) | 2011-09-07 | 2016-06-30 | Тева Фармасьютикалз Интернэшнл Гмбх | Полиморфная форма гидрохлорида придопидина |
| TWI579272B (zh) | 2011-12-08 | 2017-04-21 | 梯瓦製藥國際有限責任公司 | 普多比啶（ｐｒｉｄｏｐｉｄｉｎｅ）之氫溴酸鹽 |
| KR20150013476A (ko) | 2012-04-04 | 2015-02-05 | 아이백스 인터내셔널 게엠베하 | 조합요법용 약학적 조성물 |
| EP2900226A4 (en) * | 2012-09-27 | 2016-03-30 | Teva Pharma | COMBINATION OF RASAGILIN AND PRIDOPIDIN FOR TREATING NEURODEGENERATIVE DISORDERS, ESPECIALLY HUNTINGTON'S DISEASE |
| JP2016523862A (ja) | 2013-06-21 | 2016-08-12 | テバ・ファーマシューティカルズ・インターナショナル・ゲーエムベーハーＴｅｖａ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｔｅｒｎａｔｉｏｎａｌ ＧｍｂＨ | ハンチントン病を治療するための高用量プリドピジンの使用 |
| HUE058288T2 (hu) | 2014-01-22 | 2022-07-28 | Prilenia Neurotherapeutics Ltd | Pridopidin módosított hatóanyag-leadású készítményei |
| TW201613859A (en) * | 2014-06-30 | 2016-04-16 | Teva Pharma | Analogs of PRIDOPIDINE, their preparation and use |
| WO2016106142A1 (en) | 2014-12-22 | 2016-06-30 | Teva Pharmaceuticals International Gmbh | L-tartrate salt of pridopidine |
| WO2016138135A1 (en) | 2015-02-25 | 2016-09-01 | Teva Pharmaceuticals International Gmbh | Sigma-1 receptor modulators for treating huntington's disease |
| EP4282479A3 (en) * | 2015-02-25 | 2024-02-21 | Prilenia Neurotherapeutics Ltd. | Use of pridopidine to treat depression or anxiety |
-
2018
- 2018-01-18 EP EP18741607.8A patent/EP3570940B1/en active Active
- 2018-01-18 ES ES18741607T patent/ES2972205T3/es active Active
- 2018-01-18 CA CA3050700A patent/CA3050700C/en active Active
- 2018-01-18 CN CN201880007913.2A patent/CN110505902B/zh active Active
- 2018-01-18 IL IL268125A patent/IL268125B2/en unknown
- 2018-01-18 JP JP2019539958A patent/JP7114604B2/ja active Active
- 2018-01-18 HU HUE18741607A patent/HUE068300T2/hu unknown
- 2018-01-18 AU AU2018210145A patent/AU2018210145B2/en active Active
- 2018-01-18 WO PCT/US2018/014169 patent/WO2018136600A1/en not_active Ceased
- 2018-01-18 DK DK18741607.8T patent/DK3570940T3/da active
- 2018-01-18 BR BR112019015000A patent/BR112019015000A2/pt not_active Application Discontinuation
- 2018-01-18 PL PL18741607.8T patent/PL3570940T3/pl unknown
-
2019
- 2019-07-17 US US16/514,167 patent/US11234973B2/en active Active
-
2022
- 2022-01-31 US US17/588,403 patent/US20220202798A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP3570940B1 (en) | 2023-12-13 |
| ES2972205T3 (es) | 2024-06-11 |
| BR112019015000A2 (pt) | 2020-04-07 |
| WO2018136600A1 (en) | 2018-07-26 |
| IL268125B2 (en) | 2023-04-01 |
| IL268125B (en) | 2022-12-01 |
| CN110505902A (zh) | 2019-11-26 |
| PL3570940T3 (pl) | 2024-06-17 |
| JP7114604B2 (ja) | 2022-08-08 |
| IL268125A (en) | 2019-09-26 |
| US11234973B2 (en) | 2022-02-01 |
| EP3570940A4 (en) | 2020-10-28 |
| CA3050700A1 (en) | 2018-07-26 |
| AU2018210145A1 (en) | 2019-08-29 |
| AU2018210145B2 (en) | 2023-06-29 |
| CN110505902B (zh) | 2022-11-11 |
| US20220202798A1 (en) | 2022-06-30 |
| US20190336488A1 (en) | 2019-11-07 |
| HUE068300T2 (hu) | 2024-12-28 |
| CA3050700C (en) | 2023-10-03 |
| EP3570940A1 (en) | 2019-11-27 |
| JP2020514313A (ja) | 2020-05-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK3570940T3 (da) | Pridopidin til anvendelse i behandling af fragilt x-syndrom | |
| EP3446667A4 (en) | Absorbent article | |
| DK3227675T3 (da) | Activin-actrii-antagonister og anvendelser til behandling af myelodysplastisk syndrom | |
| EP3437612A4 (en) | VOIDABLE ARTICLE | |
| DK3307296T3 (da) | Timp2 til anvendelse til behandling af aldringsassocierede tilstande | |
| EP3446666A4 (en) | VOIDABLE ARTICLE | |
| EP3545925A4 (en) | ABSORBENT ARTICLE | |
| DK3710000T3 (da) | Tradipitant til anvendelse til behandling af gastroparese | |
| EP3470034A4 (en) | VOIDABLE ARTICLE | |
| EP3446668A4 (en) | VOIDABLE ARTICLE | |
| EP3505148A4 (en) | VOIDABLE ARTICLE | |
| EP3449883A4 (en) | VOIDABLE ARTICLE | |
| EP3384887A4 (en) | VOIDABLE ARTICLE | |
| EP3520752A4 (en) | ABSORBENT ARTICLE | |
| EP3470036A4 (en) | VOIDABLE ARTICLE | |
| EP3437608A4 (en) | VOIDABLE ARTICLE | |
| EP3354245A4 (en) | VOIDABLE ARTICLE | |
| EP3357469A4 (en) | VOIDABLE ARTICLE | |
| EP3437607A4 (en) | VOIDABLE ARTICLE | |
| HUE058314T2 (hu) | Pridopidin alkalmazása Rett-szindróma kezelésére | |
| EP3434240A4 (en) | SUCTIONABLE ARTICLE | |
| EP3549563A4 (en) | ABSORBENT ARTICLE | |
| EP3417840A4 (en) | Absorbent article | |
| EP3384888A4 (en) | VOIDABLE ARTICLE | |
| EP3554445C0 (en) | Absorbent article |