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DK3487873T3 - Forbedret filamentøs svampevært - Google Patents

Forbedret filamentøs svampevært Download PDF

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Publication number
DK3487873T3
DK3487873T3 DK17748673.5T DK17748673T DK3487873T3 DK 3487873 T3 DK3487873 T3 DK 3487873T3 DK 17748673 T DK17748673 T DK 17748673T DK 3487873 T3 DK3487873 T3 DK 3487873T3
Authority
DK
Denmark
Prior art keywords
filamentous fungal
fungal host
improved filamentous
improved
host
Prior art date
Application number
DK17748673.5T
Other languages
English (en)
Inventor
Kaihei Kojima
Hiroshi Teramoto
Preethi Ramaiya
Original Assignee
Novozymes As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novozymes As filed Critical Novozymes As
Application granted granted Critical
Publication of DK3487873T3 publication Critical patent/DK3487873T3/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/38Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from Aspergillus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01003Glucan 1,4-alpha-glucosidase (3.2.1.3), i.e. glucoamylase

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Botany (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK17748673.5T 2016-07-22 2017-07-19 Forbedret filamentøs svampevært DK3487873T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16180774 2016-07-22
PCT/EP2017/068242 WO2018015443A1 (en) 2016-07-22 2017-07-19 Improved filamentous fungal host

Publications (1)

Publication Number Publication Date
DK3487873T3 true DK3487873T3 (da) 2021-05-25

Family

ID=56511395

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17748673.5T DK3487873T3 (da) 2016-07-22 2017-07-19 Forbedret filamentøs svampevært

Country Status (5)

Country Link
US (1) US11046736B2 (da)
EP (1) EP3487873B1 (da)
CN (1) CN109476714A (da)
DK (1) DK3487873T3 (da)
WO (1) WO2018015443A1 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11046736B2 (en) * 2016-07-22 2021-06-29 Novozymes A/S Filamentous fungal host
CN113166211A (zh) * 2018-11-28 2021-07-23 诺维信公司 改善的丝状真菌宿主细胞
CN110184260B (zh) * 2019-06-30 2021-08-10 华南理工大学 一种经优化的耐热亮氨酸氨肽酶Thelap及其编码基因与应用
US20220251581A1 (en) * 2019-07-26 2022-08-11 Novozymes A/S Modified filamentous fungal host cell
CN113388597B (zh) * 2021-06-04 2022-06-03 福州大学 一种具有抗真菌活性的几丁质酶及其基因
WO2025226596A1 (en) 2024-04-24 2025-10-30 Novozymes A/S Methods for producing secreted polypeptides

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK122686D0 (da) 1986-03-17 1986-03-17 Novo Industri As Fremstilling af proteiner
US5989870A (en) 1986-04-30 1999-11-23 Rohm Enzyme Finland Oy Method for cloning active promoters
CN1192108C (zh) 1994-06-03 2005-03-09 诺沃奇梅兹生物技术有限公司 纯化的毁丝霉属漆酶及编码该酶的核酸
WO1996000787A1 (en) 1994-06-30 1996-01-11 Novo Nordisk Biotech, Inc. Non-toxic, non-toxigenic, non-pathogenic fusarium expression system and promoters and terminators for use therein
CN1197965C (zh) 1998-10-26 2005-04-20 诺维信公司 在丝状真菌细胞内构建和筛选目的dna文库
AU4025700A (en) 1999-03-22 2000-10-09 Novo Nordisk Biotech, Inc. Promoters for expressing genes in a fungal cell
ATE394496T1 (de) * 2000-03-24 2008-05-15 Genencor Int Herstellung von sekretierten proteinen durch rekombinante eukaryotische zellen
US8389269B2 (en) * 2006-11-02 2013-03-05 Dsm Ip Assets B.V. Production of secreted proteins by filamentous fungi
EP2356242A2 (en) 2008-09-30 2011-08-17 Novozymes Inc. Methods for using positively and negatively selectable genes in a filamentous fungal cell
KR101591104B1 (ko) * 2009-06-12 2016-02-02 엘지전자 주식회사 네트워크와 연결된 서비스 프로바이더에서 epg 데이터를 처리하는 방법 및 epg 데이터를 처리하는 디지털 방송 수신기
ES2565060T3 (es) 2010-04-14 2016-03-31 Novozymes A/S Polipéptidos que tienen actividad de glucoamilasa y polinucleótidos que codifican los mismos
KR101311196B1 (ko) * 2010-12-23 2013-09-27 중앙대학교 산학협력단 진균 감염 또는 뇌수막염 치료를 위한 upr 신호전달 유전자 ire1 및 hxl1의 용도
EP2527448A1 (en) 2011-05-23 2012-11-28 Novozymes A/S Simultaneous site-specific integrations of multiple gene-copies in filamentous fungi
EP3212768A1 (en) * 2014-10-29 2017-09-06 Novozymes A/S Filamentous fungal double-mutant host cells
US11046736B2 (en) * 2016-07-22 2021-06-29 Novozymes A/S Filamentous fungal host

Also Published As

Publication number Publication date
EP3487873A1 (en) 2019-05-29
WO2018015443A1 (en) 2018-01-25
US20190169238A1 (en) 2019-06-06
US11046736B2 (en) 2021-06-29
EP3487873B1 (en) 2021-03-31
CN109476714A (zh) 2019-03-15

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