DK3487873T3 - Forbedret filamentøs svampevært - Google Patents
Forbedret filamentøs svampevært Download PDFInfo
- Publication number
- DK3487873T3 DK3487873T3 DK17748673.5T DK17748673T DK3487873T3 DK 3487873 T3 DK3487873 T3 DK 3487873T3 DK 17748673 T DK17748673 T DK 17748673T DK 3487873 T3 DK3487873 T3 DK 3487873T3
- Authority
- DK
- Denmark
- Prior art keywords
- filamentous fungal
- fungal host
- improved filamentous
- improved
- host
- Prior art date
Links
- 230000002538 fungal effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
- C07K14/38—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from Aspergillus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/14—Fungi; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01003—Glucan 1,4-alpha-glucosidase (3.2.1.3), i.e. glucoamylase
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Plant Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Botany (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16180774 | 2016-07-22 | ||
| PCT/EP2017/068242 WO2018015443A1 (en) | 2016-07-22 | 2017-07-19 | Improved filamentous fungal host |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3487873T3 true DK3487873T3 (da) | 2021-05-25 |
Family
ID=56511395
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK17748673.5T DK3487873T3 (da) | 2016-07-22 | 2017-07-19 | Forbedret filamentøs svampevært |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US11046736B2 (da) |
| EP (1) | EP3487873B1 (da) |
| CN (1) | CN109476714A (da) |
| DK (1) | DK3487873T3 (da) |
| WO (1) | WO2018015443A1 (da) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11046736B2 (en) * | 2016-07-22 | 2021-06-29 | Novozymes A/S | Filamentous fungal host |
| CN113166211A (zh) * | 2018-11-28 | 2021-07-23 | 诺维信公司 | 改善的丝状真菌宿主细胞 |
| CN110184260B (zh) * | 2019-06-30 | 2021-08-10 | 华南理工大学 | 一种经优化的耐热亮氨酸氨肽酶Thelap及其编码基因与应用 |
| US20220251581A1 (en) * | 2019-07-26 | 2022-08-11 | Novozymes A/S | Modified filamentous fungal host cell |
| CN113388597B (zh) * | 2021-06-04 | 2022-06-03 | 福州大学 | 一种具有抗真菌活性的几丁质酶及其基因 |
| WO2025226596A1 (en) | 2024-04-24 | 2025-10-30 | Novozymes A/S | Methods for producing secreted polypeptides |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK122686D0 (da) | 1986-03-17 | 1986-03-17 | Novo Industri As | Fremstilling af proteiner |
| US5989870A (en) | 1986-04-30 | 1999-11-23 | Rohm Enzyme Finland Oy | Method for cloning active promoters |
| CN1192108C (zh) | 1994-06-03 | 2005-03-09 | 诺沃奇梅兹生物技术有限公司 | 纯化的毁丝霉属漆酶及编码该酶的核酸 |
| WO1996000787A1 (en) | 1994-06-30 | 1996-01-11 | Novo Nordisk Biotech, Inc. | Non-toxic, non-toxigenic, non-pathogenic fusarium expression system and promoters and terminators for use therein |
| CN1197965C (zh) | 1998-10-26 | 2005-04-20 | 诺维信公司 | 在丝状真菌细胞内构建和筛选目的dna文库 |
| AU4025700A (en) | 1999-03-22 | 2000-10-09 | Novo Nordisk Biotech, Inc. | Promoters for expressing genes in a fungal cell |
| ATE394496T1 (de) * | 2000-03-24 | 2008-05-15 | Genencor Int | Herstellung von sekretierten proteinen durch rekombinante eukaryotische zellen |
| US8389269B2 (en) * | 2006-11-02 | 2013-03-05 | Dsm Ip Assets B.V. | Production of secreted proteins by filamentous fungi |
| EP2356242A2 (en) | 2008-09-30 | 2011-08-17 | Novozymes Inc. | Methods for using positively and negatively selectable genes in a filamentous fungal cell |
| KR101591104B1 (ko) * | 2009-06-12 | 2016-02-02 | 엘지전자 주식회사 | 네트워크와 연결된 서비스 프로바이더에서 epg 데이터를 처리하는 방법 및 epg 데이터를 처리하는 디지털 방송 수신기 |
| ES2565060T3 (es) | 2010-04-14 | 2016-03-31 | Novozymes A/S | Polipéptidos que tienen actividad de glucoamilasa y polinucleótidos que codifican los mismos |
| KR101311196B1 (ko) * | 2010-12-23 | 2013-09-27 | 중앙대학교 산학협력단 | 진균 감염 또는 뇌수막염 치료를 위한 upr 신호전달 유전자 ire1 및 hxl1의 용도 |
| EP2527448A1 (en) | 2011-05-23 | 2012-11-28 | Novozymes A/S | Simultaneous site-specific integrations of multiple gene-copies in filamentous fungi |
| EP3212768A1 (en) * | 2014-10-29 | 2017-09-06 | Novozymes A/S | Filamentous fungal double-mutant host cells |
| US11046736B2 (en) * | 2016-07-22 | 2021-06-29 | Novozymes A/S | Filamentous fungal host |
-
2017
- 2017-07-19 US US16/319,780 patent/US11046736B2/en active Active
- 2017-07-19 CN CN201780044103.XA patent/CN109476714A/zh active Pending
- 2017-07-19 EP EP17748673.5A patent/EP3487873B1/en active Active
- 2017-07-19 DK DK17748673.5T patent/DK3487873T3/da active
- 2017-07-19 WO PCT/EP2017/068242 patent/WO2018015443A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP3487873A1 (en) | 2019-05-29 |
| WO2018015443A1 (en) | 2018-01-25 |
| US20190169238A1 (en) | 2019-06-06 |
| US11046736B2 (en) | 2021-06-29 |
| EP3487873B1 (en) | 2021-03-31 |
| CN109476714A (zh) | 2019-03-15 |
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