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DK3336197T3 - Epigenetiske markører og relaterede fremgangsmåder og midler til detektion og behandling af ovariekræft - Google Patents

Epigenetiske markører og relaterede fremgangsmåder og midler til detektion og behandling af ovariekræft Download PDF

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Publication number
DK3336197T3
DK3336197T3 DK16204822.7T DK16204822T DK3336197T3 DK 3336197 T3 DK3336197 T3 DK 3336197T3 DK 16204822 T DK16204822 T DK 16204822T DK 3336197 T3 DK3336197 T3 DK 3336197T3
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Prior art keywords
agents
detection
treatment
ovarian cancer
related methods
Prior art date
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DK16204822.7T
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Danish (da)
English (en)
Inventor
Martin Widschwendter
Allison Jones
Iona Evans
Harri Lemppiäinen
Johannes Eichner
Tamas Rujan
Timo Wittenberger
Tobias Paprotka
Benjamin Wahl
Original Assignee
Eurofins Genomics Europe Sequencing GmbH
Genedata AG
Ucl Business Ltd
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Application filed by Eurofins Genomics Europe Sequencing GmbH, Genedata AG, Ucl Business Ltd filed Critical Eurofins Genomics Europe Sequencing GmbH
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Publication of DK3336197T3 publication Critical patent/DK3336197T3/da

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/10Signal processing, e.g. from mass spectrometry [MS] or from PCR
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/112Disease subtyping, staging or classification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/154Methylation markers

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medical Informatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Public Health (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Evolutionary Biology (AREA)
  • Theoretical Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Data Mining & Analysis (AREA)
  • Primary Health Care (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Databases & Information Systems (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Signal Processing (AREA)
  • Artificial Intelligence (AREA)
  • Evolutionary Computation (AREA)
  • Bioethics (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Software Systems (AREA)
DK16204822.7T 2016-12-16 2016-12-16 Epigenetiske markører og relaterede fremgangsmåder og midler til detektion og behandling af ovariekræft DK3336197T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP16204822.7A EP3336197B1 (fr) 2016-12-16 2016-12-16 Marqueurs épigénétiques et procédés associés et moyens de détection et de gestion du cancer des ovaires

Publications (1)

Publication Number Publication Date
DK3336197T3 true DK3336197T3 (da) 2022-07-11

Family

ID=57609702

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16204822.7T DK3336197T3 (da) 2016-12-16 2016-12-16 Epigenetiske markører og relaterede fremgangsmåder og midler til detektion og behandling af ovariekræft

Country Status (9)

Country Link
US (3) US20190323090A1 (fr)
EP (3) EP3336197B1 (fr)
AU (2) AU2017378196A1 (fr)
CA (2) CA3047208A1 (fr)
DK (1) DK3336197T3 (fr)
HU (1) HUE059194T2 (fr)
IL (2) IL267302A (fr)
PL (1) PL3336197T3 (fr)
WO (2) WO2018109212A1 (fr)

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CN107532124B (zh) 2015-03-27 2022-08-09 精密科学公司 检测食管疾病
EP3336197B1 (fr) 2016-12-16 2022-04-06 Eurofins Genomics Europe Sequencing GmbH Marqueurs épigénétiques et procédés associés et moyens de détection et de gestion du cancer des ovaires
AU2018342449A1 (en) * 2017-09-26 2020-04-16 Juno Diagnostics, Inc. Devices, systems and methods for biomarker analysis
TWI834642B (zh) 2018-03-13 2024-03-11 美商格瑞爾有限責任公司 異常片段偵測及分類
US12462935B2 (en) 2018-03-30 2025-11-04 Nucleix Ltd. Deep learning-based methods, devices, and systems for prenatal testing
CA3102658A1 (fr) * 2018-06-27 2020-01-02 The Trustees Of Indiana University Procedes d'analyse de l'adn dans l'urine
EP3867405A4 (fr) 2018-10-17 2022-07-20 The University of Queensland Biomarqueur épigénétique et ses utilisations
WO2020132572A1 (fr) 2018-12-21 2020-06-25 Grail, Inc. Source de déconvolution d'origine basée sur des fragments de méthylation dans des échantillons d'adn acellulaire
KR102185527B1 (ko) * 2019-03-29 2020-12-02 가톨릭대학교 산학협력단 갑상선암 진단을 위한 갑상선암 특이적 dna 메틸화 바이오 마커의 검출 방법 및 조성물
WO2021003485A1 (fr) * 2019-07-03 2021-01-07 The Board Of Trustees Of The Leland Stanford Junior University Procédés d'évaluation de résultat clinique basé sur des probabilités mises à jour et traitements associés
US20220316013A1 (en) * 2019-08-23 2022-10-06 Agex Therapeutics, Inc. Differentially-methylated regions of the genome useful as markers of embryo-adult transitions
EP4028586A4 (fr) * 2019-09-13 2023-10-04 University Health Network Détection d'adn tumoral circulant à l'aide d'une capture hybride à double brin
CN112921086B (zh) * 2019-12-06 2022-12-02 广州医科大学附属第三医院(广州重症孕产妇救治中心、广州柔济医院) Circ-CRIM1作为卵巢癌诊断标志物及其应用
CN112921085B (zh) * 2019-12-06 2022-06-10 广州医科大学附属第三医院(广州重症孕产妇救治中心、广州柔济医院) Circ-NOLC1作为卵巢癌诊断标志物及其应用
US20230042332A1 (en) 2019-12-24 2023-02-09 Vib Vzw Disease Detection in Liquid Biopsies
JP2024506854A (ja) * 2021-01-29 2024-02-15 マヨ ファウンデーション フォア メディカル エデュケーション アンド リサーチ 複数の種類のがんの有無の検出
WO2022178108A1 (fr) * 2021-02-17 2022-08-25 University Of Southern California Test de méthylation d'adn acellulaire
EP4170661A1 (fr) * 2021-10-19 2023-04-26 Institut National de la Santé et de la Recherche Médicale (INSERM) Analyse de profil de méthylation à l'aide d'un procédé de lissage
WO2023183812A2 (fr) * 2022-03-21 2023-09-28 Billion Toone, Inc. Numération de molécules d'adn libre circulant méthylé pour une surveillance de traitement
KR20250148656A (ko) 2023-02-17 2025-10-14 이지 바이오메드 씨오., 엘티디. 췌장암의 조기 예측, 치료 반응, 재발 및 예후 모니터링을 위한 방법

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US6582908B2 (en) 1990-12-06 2003-06-24 Affymetrix, Inc. Oligonucleotides
US5786146A (en) 1996-06-03 1998-07-28 The Johns Hopkins University School Of Medicine Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids
US6017704A (en) 1996-06-03 2000-01-25 The Johns Hopkins University School Of Medicine Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids
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EP1862555A1 (fr) 2006-05-29 2007-12-05 Klinikum der Universität Regensburg Moyens et procédés de diagnostic du cancer ou prédisposition correspondante
EP2304057B1 (fr) * 2008-06-17 2014-09-17 Signature Diagnostics AG Methode pour detecter du cancer de l'ovaire
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WO2015116837A1 (fr) * 2014-01-30 2015-08-06 The Regents Of The University Of California Haplotypage de méthylation pour le diagnostic non invasif (monod)
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Also Published As

Publication number Publication date
EP3336197B1 (fr) 2022-04-06
IL267302A (en) 2019-08-29
EP3555309C0 (fr) 2023-09-13
PL3336197T3 (pl) 2022-08-08
EP3555308B1 (fr) 2023-12-13
EP3555308C0 (fr) 2023-12-13
WO2018109217A1 (fr) 2018-06-21
US12391995B2 (en) 2025-08-19
CA3047208A1 (fr) 2018-06-21
AU2017378196A1 (en) 2019-07-04
WO2018109212A1 (fr) 2018-06-21
IL267300A (en) 2019-08-29
EP3555308A1 (fr) 2019-10-23
US20240200142A1 (en) 2024-06-20
CA3047202A1 (fr) 2018-06-21
EP3555309A1 (fr) 2019-10-23
US20190323090A1 (en) 2019-10-24
HUE059194T2 (hu) 2022-10-28
US20190330703A1 (en) 2019-10-31
EP3555309B1 (fr) 2023-09-13
AU2017375038A1 (en) 2019-07-04
EP3336197A1 (fr) 2018-06-20
US11920200B2 (en) 2024-03-05

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