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DK3311824T3 - Cd47 målrettede terapier til behandlingen af infektionssygdomme - Google Patents

Cd47 målrettede terapier til behandlingen af infektionssygdomme Download PDF

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Publication number
DK3311824T3
DK3311824T3 DK17194591.8T DK17194591T DK3311824T3 DK 3311824 T3 DK3311824 T3 DK 3311824T3 DK 17194591 T DK17194591 T DK 17194591T DK 3311824 T3 DK3311824 T3 DK 3311824T3
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DK
Denmark
Prior art keywords
treatment
infectious diseases
targeted treatments
treatments
targeted
Prior art date
Application number
DK17194591.8T
Other languages
English (en)
Inventor
Kipp Weiskopf
Kim J Hasenkrug
Cheryl A Stoddart
Joseph M Mccune
Irving L Weissman
Original Assignee
Univ Leland Stanford Junior
Us Health
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Leland Stanford Junior, Us Health, Univ California filed Critical Univ Leland Stanford Junior
Application granted granted Critical
Publication of DK3311824T3 publication Critical patent/DK3311824T3/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1774Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Radiation-Therapy Devices (AREA)
DK17194591.8T 2013-02-05 2014-02-05 Cd47 målrettede terapier til behandlingen af infektionssygdomme DK3311824T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361761133P 2013-02-05 2013-02-05
EP14748994.2A EP2953633B1 (en) 2013-02-05 2014-02-05 Cd47 targeted therapies for the treatment of infectious disease

Publications (1)

Publication Number Publication Date
DK3311824T3 true DK3311824T3 (da) 2020-04-14

Family

ID=51300110

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17194591.8T DK3311824T3 (da) 2013-02-05 2014-02-05 Cd47 målrettede terapier til behandlingen af infektionssygdomme

Country Status (10)

Country Link
US (6) US9771428B2 (da)
EP (4) EP2953633B1 (da)
CA (1) CA2900256C (da)
DK (1) DK3311824T3 (da)
ES (4) ES2794700T3 (da)
HR (1) HRP20200565T1 (da)
PL (2) PL4119153T3 (da)
PT (1) PT3721888T (da)
SI (1) SI3721888T1 (da)
WO (1) WO2014124028A1 (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL4119153T3 (pl) * 2013-02-05 2024-09-02 The Board Of Trustees Of The Leland Stanford Junior University Terapie ukierunkowane na cd47 w leczeniu choroby zakaźnej
US10329354B2 (en) 2013-09-18 2019-06-25 The Board Of Trustees Of The Leland Stanford Junior University Modulation of efferocytosis pathways for treatment of atherosclerotic disease
EP4218812A1 (en) * 2015-02-27 2023-08-02 The Board of Trustees of the Leland Stanford Junior University Combination therapy for treatment of atherosclerosis
WO2016187226A1 (en) * 2015-05-18 2016-11-24 Ab Initio Biotherapeutics, Inc. Sirp polypeptide compositions and methods of use
JP6898303B2 (ja) 2015-08-07 2021-07-07 エーエルエックス オンコロジー インコーポレイテッド Sirp−アルファドメインまたはそのバリアントを有する構築物
US12344669B2 (en) 2016-06-17 2025-07-01 Changchun Genescience Pharmaceutical Co., Ltd. Anti-CD47 monoclonal antibody and use thereof
CN106084052B (zh) * 2016-06-17 2019-12-27 长春金赛药业股份有限公司 抗cd47单克隆抗体及其应用
JOP20190009A1 (ar) 2016-09-21 2019-01-27 Alx Oncology Inc أجسام مضادة ضد بروتين ألفا منظم للإشارات وطرق استخدامها
US10995152B2 (en) 2016-10-26 2021-05-04 The Board Of Trustees Of The Leland Stanford Junior University Modified immunoglobulin hinge regions to reduce hemagglutination
JP7173971B2 (ja) 2016-12-09 2022-11-16 アレクトル エルエルシー 抗SIRP-α抗体及びその使用方法
US11319360B2 (en) 2016-12-29 2022-05-03 Korea Institute Of Science And Technology Exosome-based anticancer agent
PL3658141T3 (pl) 2017-07-24 2023-06-12 Stichting Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Leczenie stanów patologicznych przez bezpośrednie i pośrednie celowanie w oddziaływanie sirpalfa - cd47
ES2963157T3 (es) 2017-07-26 2024-03-25 Forty Seven Inc Anticuerpos anti-SIRP-alfa y métodos relacionados
AU2018312222B2 (en) 2017-08-02 2024-11-21 Phanes Therapeutics, Inc. Anti-CD47 antibodies and uses thereof
AR113862A1 (es) 2017-12-01 2020-06-17 Seattle Genetics Inc Anticuerpos anti-cd47 y sus usos para tratar cáncer
PE20201265A1 (es) 2018-03-21 2020-11-19 Alx Oncology Inc Anticuerpos contra proteina alfa reguladora de senal y metodos de uso
GB201807945D0 (en) 2018-05-16 2018-06-27 Ospedale San Raffaele Srl Vector production
PE20210342A1 (es) 2018-05-25 2021-02-23 Alector Llc Anticuerpos anti-sirpa y metodos de utilizacion de los mismos
US11591390B2 (en) 2018-09-27 2023-02-28 Celgene Corporation SIRP-α binding proteins and methods of use thereof
BR112021005585A2 (pt) 2018-09-27 2021-06-29 Celgene Corporation proteínas de ligação a sirpa e métodos de uso das mesmas
US12331320B2 (en) 2018-10-10 2025-06-17 The Research Foundation For The State University Of New York Genome edited cancer cell vaccines
AU2019370031A1 (en) * 2018-10-29 2021-05-27 Umc Utrecht Holding B.V. IgA mediated killing of aberrant cells by CD47- SIRPα checkpoint inhibition of neutrophils
US11613564B2 (en) 2019-05-31 2023-03-28 ALX Oncology Inc. Methods of treating cancer
EP3756688A1 (en) 2019-06-25 2020-12-30 Université de Nantes Inhibitor of surface protein (sp-d) / sirpa / shp2 pathway for use in the prevention and/or treatment of secondary infection
JP2024520902A (ja) 2021-05-13 2024-05-27 エーエルエックス オンコロジー インコーポレイテッド がんを治療するための併用療法
KR102690136B1 (ko) * 2021-06-30 2024-07-31 연세대학교 산학협력단 바이러스 및 박테리아의 중복 감염 치료용 조성물

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2189808T3 (es) * 1993-10-15 2003-07-16 Cytrx Corp Composiciones de aporte terapeutico y metodos de uso de las mismas.
US8377448B2 (en) 2006-05-15 2013-02-19 The Board Of Trustees Of The Leland Standford Junior University CD47 related compositions and methods for treating immunological diseases and disorders
EP2111869A1 (en) * 2008-04-23 2009-10-28 Stichting Sanquin Bloedvoorziening Compositions and methods to enhance the immune system
PL2429574T3 (pl) 2009-05-15 2015-12-31 Univ Health Network Kompozycje i sposoby leczenia nowotworów hematologicznych celujące w oddziaływanie SIRP-CD47
HRP20170254T1 (hr) 2010-05-14 2017-04-21 The Board of Trustees of the Leland Stanford Junior University Office of the General Counsel Humanizirana i kimerna monoklonska protutijela usmjerena na cd47
PL4119153T3 (pl) * 2013-02-05 2024-09-02 The Board Of Trustees Of The Leland Stanford Junior University Terapie ukierunkowane na cd47 w leczeniu choroby zakaźnej

Also Published As

Publication number Publication date
SI3721888T1 (sl) 2023-04-28
EP3311824A1 (en) 2018-04-25
US9771428B2 (en) 2017-09-26
US20150376288A1 (en) 2015-12-31
US10184004B2 (en) 2019-01-22
EP4119153B1 (en) 2024-04-24
US20170362332A1 (en) 2017-12-21
US20200354469A1 (en) 2020-11-12
CA2900256A1 (en) 2014-08-14
ES2983571T3 (es) 2024-10-23
US20230406952A1 (en) 2023-12-21
EP3721888B1 (en) 2022-07-20
ES2928001T3 (es) 2022-11-14
US20190092873A1 (en) 2019-03-28
ES2649165T3 (es) 2018-01-10
CA2900256C (en) 2023-03-21
EP3721888A1 (en) 2020-10-14
WO2014124028A1 (en) 2014-08-14
US11230607B2 (en) 2022-01-25
PL3721888T3 (pl) 2023-04-11
EP4119153A1 (en) 2023-01-18
ES2794700T3 (es) 2020-11-18
US11780931B2 (en) 2023-10-10
EP2953633A4 (en) 2016-09-14
PL4119153T3 (pl) 2024-09-02
HRP20200565T1 (hr) 2020-08-07
EP4119153C0 (en) 2024-04-24
PT3721888T (pt) 2022-11-02
US10723803B2 (en) 2020-07-28
EP2953633A1 (en) 2015-12-16
US20220098322A1 (en) 2022-03-31
US12410259B2 (en) 2025-09-09
EP2953633B1 (en) 2017-10-04
EP3311824B1 (en) 2020-03-25

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