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DK3224356T3 - Metoder til rekombinant udtrykkelse af beta-glucosidase-gen - Google Patents

Metoder til rekombinant udtrykkelse af beta-glucosidase-gen Download PDF

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Publication number
DK3224356T3
DK3224356T3 DK15862373.6T DK15862373T DK3224356T3 DK 3224356 T3 DK3224356 T3 DK 3224356T3 DK 15862373 T DK15862373 T DK 15862373T DK 3224356 T3 DK3224356 T3 DK 3224356T3
Authority
DK
Denmark
Prior art keywords
beta
methods
recombinant expression
glucosidase gene
glucosidase
Prior art date
Application number
DK15862373.6T
Other languages
English (en)
Inventor
Ana Zeng
Gang Wang
Qi Feng
Jun Xu
Original Assignee
Wilmar Shanghai Biotechnology Res & Dev Ct Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wilmar Shanghai Biotechnology Res & Dev Ct Co Ltd filed Critical Wilmar Shanghai Biotechnology Res & Dev Ct Co Ltd
Application granted granted Critical
Publication of DK3224356T3 publication Critical patent/DK3224356T3/da

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405Glucanases
    • C12N9/2434Glucanases acting on beta-1,4-glucosidic bonds
    • C12N9/2445Beta-glucosidase (3.2.1.21)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/58Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/02Monosaccharides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/14Preparation of compounds containing saccharide radicals produced by the action of a carbohydrase (EC 3.2.x), e.g. by alpha-amylase, e.g. by cellulase, hemicellulase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01021Beta-glucosidase (3.2.1.21)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/23Aspartic endopeptidases (3.4.23)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/23Aspartic endopeptidases (3.4.23)
    • C12Y304/23023Mucorpepsin (3.4.23.23)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
DK15862373.6T 2014-11-27 2015-11-27 Metoder til rekombinant udtrykkelse af beta-glucosidase-gen DK3224356T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201410699758.9A CN105695439B (zh) 2014-11-27 2014-11-27 一种β-葡萄糖苷酶基因的重组表达方法
PCT/CN2015/000826 WO2016082305A1 (en) 2014-11-27 2015-11-27 Methods for recombinant expression of beta-glucosidase gene

Publications (1)

Publication Number Publication Date
DK3224356T3 true DK3224356T3 (da) 2020-07-13

Family

ID=56073431

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15862373.6T DK3224356T3 (da) 2014-11-27 2015-11-27 Metoder til rekombinant udtrykkelse af beta-glucosidase-gen

Country Status (6)

Country Link
US (1) US9969995B2 (da)
EP (1) EP3224356B9 (da)
CN (1) CN105695439B (da)
DK (1) DK3224356T3 (da)
ES (1) ES2805092T3 (da)
WO (1) WO2016082305A1 (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106818885B (zh) * 2017-02-20 2021-05-14 华南理工大学 一种酸性蛋白酶在制备抑制病原菌制剂中的应用
CN106834336B (zh) * 2017-02-20 2020-12-22 华南理工大学 一种哈茨木霉酸性蛋白酶p6281的异源表达及纯化方法
CN106978409B (zh) * 2017-04-26 2020-09-11 福建福大百特生物科技有限公司 一种α-葡萄糖苷酶的高效制备方法
CN107365780A (zh) * 2017-08-10 2017-11-21 广东省生物资源应用研究所 一种黄胸散白蚁唾液腺β‑糖苷酶基因的克隆及原核表达方法
CN111876434B (zh) * 2020-07-23 2023-05-16 江西省科学院微生物研究所 密码子优化的β-葡萄糖苷酶基因及其表达载体
CN113403209B (zh) * 2021-07-30 2022-08-26 西南大学 天冬氨酸蛋白酶基因在改良球孢白僵菌菌株中的应用
CN114276954B (zh) * 2021-12-07 2023-09-26 广西大学 一株发根农杆菌菌株at13及其应用
CN118006573A (zh) * 2024-01-18 2024-05-10 华东理工大学 一种还原糖氧化酶及其分泌表达菌株的构建和应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6268196B1 (en) * 1993-12-17 2001-07-31 Genencor International, Inc. Method and compositions for treating cellulose containing fabrics using truncated cellulase enzyme compositions
CA2838451C (en) * 2004-03-25 2017-10-24 Novozymes, Inc. Methods for degrading or converting plant cell wall polysaccharides
BRPI0714870A2 (pt) 2006-07-21 2013-05-28 Novozymes Inc mÉtodo para produzir um polipeptÍdeo secretado tendo atividade biolàgica, proteÍna de fusço isolada, polinucleotÍdeo isolado, construÇço de proteÍna de fusço, vetor de expressço, cÉlula hospedeira féngica, mÉtodos para degradar ou conventer um material celulàsico e para produzir uma substÂncia
EP2250257A1 (en) 2008-03-07 2010-11-17 Danisco US Inc. Expression of catalase in trichoderma
US8900847B2 (en) * 2009-09-30 2014-12-02 Codexis, Inc. Polynucleotides encoding recombinant C1 beta-glucosidase for production of sugars from cellulosic biomass
JP2011205992A (ja) * 2010-03-30 2011-10-20 National Institute Of Advanced Industrial Science & Technology グルコース存在下で活性を増加するβ−グルコシダーゼ
CN103339252A (zh) * 2010-11-18 2013-10-02 诺维信股份有限公司 具有纤维素分解增强活性的嵌合多肽及其编码多核苷酸
SG190321A1 (en) * 2010-11-24 2013-06-28 Novartis Int Pharm Ltd Fusion enzymes having n-acetylglucosaminyltransferase activity
CN102220369B (zh) 2011-05-11 2012-10-10 天津大学 里氏木霉β-葡萄糖苷酶基因BGL1的重组载体、重组菌及在重组菌中的表达
DK2791350T3 (da) * 2011-12-13 2019-05-06 Danisco Us Inc Enzymcocktails fremstillet af blandede kulturer
WO2014145768A2 (en) * 2013-03-15 2014-09-18 Bp Corporation North America Inc. Use of non-fungal 5' utrs in filamentous fungi

Also Published As

Publication number Publication date
EP3224356B1 (en) 2020-04-29
EP3224356A4 (en) 2018-05-09
CN105695439B (zh) 2023-08-01
WO2016082305A1 (en) 2016-06-02
CN105695439A (zh) 2016-06-22
EP3224356A1 (en) 2017-10-04
US20170327807A1 (en) 2017-11-16
US9969995B2 (en) 2018-05-15
EP3224356B9 (en) 2020-11-04
ES2805092T3 (es) 2021-02-10

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