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DK3298008T3 - Krystallinsk form af forbindelsen (s)-3-{4-[5-(2-cyclopentyl-6-methoxy-pyridin-4-yl)-[1,2,4]oxadiazol-3-yl]-2-ethyl-6-methyl-phenoxy}-propan-1,2-diol - Google Patents

Krystallinsk form af forbindelsen (s)-3-{4-[5-(2-cyclopentyl-6-methoxy-pyridin-4-yl)-[1,2,4]oxadiazol-3-yl]-2-ethyl-6-methyl-phenoxy}-propan-1,2-diol Download PDF

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Publication number
DK3298008T3
DK3298008T3 DK16724387.2T DK16724387T DK3298008T3 DK 3298008 T3 DK3298008 T3 DK 3298008T3 DK 16724387 T DK16724387 T DK 16724387T DK 3298008 T3 DK3298008 T3 DK 3298008T3
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Prior art keywords
oxadiazol
pyridin
cyclopentyl
phenoxy
diol
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DK16724387.2T
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English (en)
Inventor
Cyrille Lescop
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Idorsia Pharmaceuticals Ltd
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4245—Oxadiazoles
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
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    • C07B2200/13—Crystalline forms, e.g. polymorphs
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    • G01N23/20—Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups G01N3/00 – G01N17/00, G01N21/00 or G01N22/00 by using diffraction of the radiation by the materials, e.g. for investigating crystal structure; by using scattering of the radiation by the materials, e.g. for investigating non-crystalline materials; by using reflection of the radiation by the materials
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DK16724387.2T 2015-05-20 2016-05-19 Krystallinsk form af forbindelsen (s)-3-{4-[5-(2-cyclopentyl-6-methoxy-pyridin-4-yl)-[1,2,4]oxadiazol-3-yl]-2-ethyl-6-methyl-phenoxy}-propan-1,2-diol DK3298008T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP2015061153 2015-05-20
PCT/EP2016/061200 WO2016184939A1 (en) 2015-05-20 2016-05-19 Crystalline form of the compound (s)-3-{4-[5-(2-cyclopentyl-6-methoxy-pyridin-4-yl)-[1,2,4]oxadiazol-3-yl]-2-ethyl-6-methyl-phenoxy}-propane-1,2-diol

Publications (1)

Publication Number Publication Date
DK3298008T3 true DK3298008T3 (da) 2020-02-10

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DK16724387.2T DK3298008T3 (da) 2015-05-20 2016-05-19 Krystallinsk form af forbindelsen (s)-3-{4-[5-(2-cyclopentyl-6-methoxy-pyridin-4-yl)-[1,2,4]oxadiazol-3-yl]-2-ethyl-6-methyl-phenoxy}-propan-1,2-diol

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US (4) US10385043B2 (da)
EP (1) EP3298008B1 (da)
JP (1) JP6674967B2 (da)
KR (2) KR102220848B1 (da)
CN (2) CN114573574B (da)
AU (1) AU2016263472B2 (da)
BR (1) BR112017024785B1 (da)
CA (1) CA2981130C (da)
CL (1) CL2017002822A1 (da)
CY (1) CY1122506T1 (da)
DK (1) DK3298008T3 (da)
EA (1) EA035133B1 (da)
ES (1) ES2770348T3 (da)
HR (1) HRP20200001T1 (da)
HU (1) HUE047646T2 (da)
IL (1) IL255718B (da)
LT (1) LT3298008T (da)
MA (1) MA42107B1 (da)
MX (1) MX373293B (da)
MY (1) MY192358A (da)
PH (1) PH12017502097B1 (da)
PL (1) PL3298008T3 (da)
PT (1) PT3298008T (da)
RS (1) RS59788B1 (da)
SG (1) SG11201708794PA (da)
SI (1) SI3298008T1 (da)
TW (1) TWI711609B (da)
UA (1) UA119818C2 (da)
WO (1) WO2016184939A1 (da)

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UA129627C2 (uk) 2019-10-31 2025-06-18 Ідорсія Фармасьютікалз Лтд Комбінація антагоніста cxcr7 з модулятором рецептора s1p1
WO2021148314A1 (en) 2020-01-20 2021-07-29 Idorsia Pharmaceuticals Ltd Accelerated elimination of (s)-3-{4-[5-(2-cyclopentyl-6-methoxy-pyridin-4-yl)-[1,2,4]oxadiazol-3-yl]-2-ethyl-6-methyl-phenoxy}-propane-1,2-diol
EP4212156A1 (en) 2022-01-13 2023-07-19 Abivax Combination of 8-chloro-n-(4-(trifluoromethoxy)phenyl)quinolin-2-amine and its derivatives with a s1p receptor modulator
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