DK3286311T3 - Fremgangsmåde til behandling af maligniteter - Google Patents
Fremgangsmåde til behandling af maligniteter Download PDFInfo
- Publication number
- DK3286311T3 DK3286311T3 DK16769720.0T DK16769720T DK3286311T3 DK 3286311 T3 DK3286311 T3 DK 3286311T3 DK 16769720 T DK16769720 T DK 16769720T DK 3286311 T3 DK3286311 T3 DK 3286311T3
- Authority
- DK
- Denmark
- Prior art keywords
- malignities
- treating
- procedure
- treating malignities
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/0091—Purification or manufacturing processes for gene therapy compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/208—IL-12
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/327—Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5434—IL-12
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36002—Cancer treatment, e.g. tumour
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/22—Vectors comprising a coding region that has been codon optimised for expression in a respective host
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Radiology & Medical Imaging (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Endocrinology (AREA)
- Toxicology (AREA)
- Manufacturing & Machinery (AREA)
- Biotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562138793P | 2015-03-26 | 2015-03-26 | |
| US201662309131P | 2016-03-16 | 2016-03-16 | |
| PCT/US2016/024079 WO2016154473A1 (en) | 2015-03-26 | 2016-03-24 | Method for the treatment of malignancies |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3286311T3 true DK3286311T3 (da) | 2021-05-17 |
Family
ID=56978697
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK16769720.0T DK3286311T3 (da) | 2015-03-26 | 2016-03-24 | Fremgangsmåde til behandling af maligniteter |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US10426847B2 (da) |
| EP (2) | EP3881860A1 (da) |
| JP (2) | JP6879996B2 (da) |
| CA (1) | CA2981049A1 (da) |
| DK (1) | DK3286311T3 (da) |
| ES (1) | ES2873093T3 (da) |
| PL (1) | PL3286311T3 (da) |
| WO (1) | WO2016154473A1 (da) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA201691073A1 (ru) | 2013-12-05 | 2016-12-30 | РФЕМБ ХОЛДИНГС, ЭлЭлСи | Иммунотерапия рака с помощью радиочастотного электрического пробоя мембраны (rf-emb) |
| US11141216B2 (en) | 2015-01-30 | 2021-10-12 | Immunsys, Inc. | Radio-frequency electrical membrane breakdown for the treatment of high risk and recurrent prostate cancer, unresectable pancreatic cancer, tumors of the breast, melanoma or other skin malignancies, sarcoma, soft tissue tumors, ductal carcinoma, neoplasia, and intra and extra luminal abnormal tissue |
| DK3286311T3 (da) | 2015-03-26 | 2021-05-17 | Oncosec Medical Inc | Fremgangsmåde til behandling af maligniteter |
| US10478494B2 (en) | 2015-04-03 | 2019-11-19 | Astex Therapeutics Ltd | FGFR/PD-1 combination therapy for the treatment of cancer |
| EP3402517B1 (en) | 2016-01-15 | 2025-08-20 | RFEMB Holdings, LLC | Immunologic treatment of cancer by using a tumor ablation technic together with a combination of a ctla-4 inhibitor, a pd-1 inhibitor and gm-csf |
| US12403305B2 (en) | 2016-06-27 | 2025-09-02 | Galvanize Therapeutics, Inc. | Immunostimulation in the treatment of viral infection |
| WO2018005511A1 (en) | 2016-06-27 | 2018-01-04 | Gala Therapeutics, Inc. | Generator and a catheter with an electrode and a method for treating a lung passageway |
| EP3515472A4 (en) * | 2016-09-23 | 2020-04-29 | OncoSec Medical Incorporated | MODULATION OF RESPONSES TO THERAPY BY CHECKPOINT INHIBITOR |
| WO2018068201A1 (en) * | 2016-10-11 | 2018-04-19 | Nanjing Legend Biotech Co., Ltd. | Single-domain antibodies and variants thereof against ctla-4 |
| GB201710973D0 (en) | 2017-07-07 | 2017-08-23 | Avacta Life Sciences Ltd | Scaffold proteins |
| WO2019133608A1 (en) | 2017-12-26 | 2019-07-04 | Gala Therapeutics, Inc. | Optimization of energy delivery for various applications |
| WO2019129221A1 (en) | 2017-12-28 | 2019-07-04 | Nanjing Legend Biotech Co., Ltd. | Single-domain antibodies and variants thereof against tigit |
| WO2019136305A1 (en) * | 2018-01-04 | 2019-07-11 | Neumedicines Inc. | Cell-based and immune checkpoint inhibitor therapies combined with il-12 for treating cancer |
| KR20250114571A (ko) | 2018-01-15 | 2025-07-29 | 난징 레전드 바이오테크 씨오., 엘티디. | Pd-1에 대한 단일-도메인 항체 및 이의 변이체 |
| US12318450B2 (en) | 2019-06-05 | 2025-06-03 | Emory University | Photolysis to unlock caged protein therapeutics |
| JP7586890B2 (ja) | 2019-07-16 | 2024-11-19 | ガルヴァナイズ セラピューティクス,インコーポレイテッド | パルス電界による生殖器の治療 |
| BR112022002406A2 (pt) | 2019-08-12 | 2022-07-19 | Purinomia Biotech Inc | Métodos e composições para promover e potencializar respostas imunes mediadas por célula t através do alvejamento de adcc de células que expressam cd39 |
| GB2700048A (en) | 2019-09-18 | 2025-08-13 | Aldevron Llc | synthetic dna vectors and method of use |
| TW202128775A (zh) | 2019-10-16 | 2021-08-01 | 英商阿法克塔生命科學有限公司 | PD-L1抑制劑-TGFβ抑制劑雙特異性藥物部分 |
| GB202101299D0 (en) | 2020-06-09 | 2021-03-17 | Avacta Life Sciences Ltd | Diagnostic polypetides and methods |
| KR102490645B1 (ko) * | 2020-07-16 | 2023-01-25 | 고려대학교 산학협력단 | 흡수에너지 기반 전기장 암치료 계획 시스템 및 방법 |
| EP4288140A1 (en) * | 2021-02-05 | 2023-12-13 | Iovance Biotherapeutics, Inc. | Adjuvant therapy for cancer |
| WO2022234003A1 (en) | 2021-05-07 | 2022-11-10 | Avacta Life Sciences Limited | Cd33 binding polypeptides with stefin a protein |
| US20240409638A1 (en) | 2021-10-07 | 2024-12-12 | Avacta Life Sciences Limited | Serum half-life extended pd-l1 binding polypeptides |
| EP4413038A1 (en) | 2021-10-07 | 2024-08-14 | Avacta Life Sciences Limited | Pd-l1 binding affimers |
| KR20230121575A (ko) | 2022-02-10 | 2023-08-18 | 주식회사 아피셀테라퓨틱스 | Cd40l에 특이적으로 결합하는 스테핀 a 단백질 변이체 및 이의 용도 |
| CN118354793A (zh) | 2022-04-29 | 2024-07-16 | 普瑞诺生物科技公司 | 用于治疗嗜酸性粒细胞驱动的疾病和病症的方法和组合物 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE371031T1 (de) | 1999-06-08 | 2007-09-15 | Uab Research Foundation | Herpes-simplex virus, das das gen von interleukin-12 exprimiert, und dessen verwendung zur behandlung von krebs |
| US7245963B2 (en) | 2002-03-07 | 2007-07-17 | Advisys, Inc. | Electrode assembly for constant-current electroporation and use |
| US8209006B2 (en) | 2002-03-07 | 2012-06-26 | Vgx Pharmaceuticals, Inc. | Constant current electroporation device and methods of use |
| US8802643B1 (en) | 2003-05-30 | 2014-08-12 | University Of South Florida | Method for the treatment of malignancies |
| AU2004247071B2 (en) * | 2003-05-30 | 2010-03-11 | University Of South Florida | Method for the treatment of malignancies |
| US7923251B2 (en) | 2005-02-23 | 2011-04-12 | The Board Of Trustees Of The Leland Stanford Junior University | Method and apparatus for avalanche-mediated transfer of agents into cells |
| US8101169B2 (en) | 2005-02-23 | 2012-01-24 | The Board Of Trustees Of The Leland Stanford Junior University | Ocular gene therapy using avalanche-mediated transfection |
| NZ563193A (en) * | 2005-05-09 | 2010-05-28 | Ono Pharmaceutical Co | Human monoclonal antibodies to programmed death 1(PD-1) and methods for treating cancer using anti-PD-1 antibodies alone or in combination with other immunotherapeutics |
| CA3101783C (en) * | 2011-10-11 | 2023-01-31 | Universitat Zurich Prorektorat Mnw | Combination medicament comprising il-12 and an agent for blockade of t-cell inhibitory molecules for tumour therapy |
| US8994173B2 (en) * | 2013-06-26 | 2015-03-31 | International Business Machines Corporation | Solder bump connection and method of making |
| EP4141032B1 (en) | 2014-11-20 | 2024-05-29 | F. Hoffmann-La Roche AG | Combination therapy of t cell activating bispecific antigen binding molecules and pd-1 axis binding antagonists |
| DK3286311T3 (da) | 2015-03-26 | 2021-05-17 | Oncosec Medical Inc | Fremgangsmåde til behandling af maligniteter |
| KR20190031424A (ko) | 2015-12-18 | 2019-03-26 | 온코섹 메디컬 인코포레이티드 | 이종 단백질 발현을 위한 플라스미드 작제물 및 사용 방법 |
| EP3515472A4 (en) | 2016-09-23 | 2020-04-29 | OncoSec Medical Incorporated | MODULATION OF RESPONSES TO THERAPY BY CHECKPOINT INHIBITOR |
-
2016
- 2016-03-24 DK DK16769720.0T patent/DK3286311T3/da active
- 2016-03-24 EP EP21171723.6A patent/EP3881860A1/en active Pending
- 2016-03-24 EP EP16769720.0A patent/EP3286311B1/en active Active
- 2016-03-24 JP JP2018502042A patent/JP6879996B2/ja active Active
- 2016-03-24 CA CA2981049A patent/CA2981049A1/en active Pending
- 2016-03-24 PL PL16769720T patent/PL3286311T3/pl unknown
- 2016-03-24 ES ES16769720T patent/ES2873093T3/es active Active
- 2016-03-24 WO PCT/US2016/024079 patent/WO2016154473A1/en not_active Ceased
- 2016-03-24 US US15/561,915 patent/US10426847B2/en active Active
-
2019
- 2019-08-26 US US16/550,475 patent/US11564999B2/en active Active
-
2021
- 2021-04-30 JP JP2021078114A patent/JP2021119181A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP3286311B1 (en) | 2021-05-05 |
| JP6879996B2 (ja) | 2021-06-02 |
| US20180318393A1 (en) | 2018-11-08 |
| US10426847B2 (en) | 2019-10-01 |
| HK1251614A1 (en) | 2019-02-01 |
| EP3881860A1 (en) | 2021-09-22 |
| EP3286311A4 (en) | 2018-11-21 |
| CA2981049A1 (en) | 2016-09-29 |
| US20200000938A1 (en) | 2020-01-02 |
| WO2016154473A1 (en) | 2016-09-29 |
| US11564999B2 (en) | 2023-01-31 |
| ES2873093T3 (es) | 2021-11-03 |
| PL3286311T3 (pl) | 2021-09-13 |
| EP3286311A1 (en) | 2018-02-28 |
| WO2016154473A8 (en) | 2017-04-20 |
| JP2021119181A (ja) | 2021-08-12 |
| JP2018509477A (ja) | 2018-04-05 |
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